Amberlyst A-15: Reusable catalyst for the synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted-1H-imidazoles under MW irradiation

SHIVAJI S PANDIT1, SWAPNIL K BHALERAO1, UDDHAV S AHER1, GORAKSHANATH L ADHAV1, VIKRAM U PANDIT2
1Post Graduate and Research Centre, Department of Chemistry, Padmashri Vikhe Patil College Pravaranagar (Loni Kd), Ahmednagar, India
2Post Graduate and Research Centre, Department of Chemistry, Fergusson College Pune, Pune, India

Tóm tắt

One-pot multi-component condensation of benzyl, aldehydes, ammonium acetate and primary amines were used for synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted-1H-imidazole derivatives under MW radiation using amberlyst A-15 as a catalysts. This catalyst has several advantages (simple work-up, low cost and reusability).

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