Adenosine Triphosphate Binding Cassette (ABC) Transporters Are Expressed and Regulated During Terminal Keratinocyte Differentiation: A Potential Role for ABCA7 in Epidermal Lipid Reorganization

Baron, 2001, Expression of multiple cytochrome p450 enzymes and multidrug resistance-associated transport proteins in human skin keratinocytes, 116, 541 Bergen, 2000, Mutations in ABCC6 cause pseudoxanthoma elasticum, Nat Genet, 25, 228, 10.1038/76109 Bligh, 1956, A rapid method of total lipid extraction and purification, Can J Biochem Physiol, 37, 911, 10.1139/y59-099 Boyce, 1983, Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture, J Invest Dermatol, 81, 33s, 10.1111/1523-1747.ep12540422 Brügger, 1997, Quantitative analysis of biological membrane lipids at the low picomole level by nano-electrospray ionization tandem mass spectrometry, Proc Natl Acad Sci USA, 94, 2339, 10.1073/pnas.94.6.2339 Candi, 1999, Transglutaminase cross-linking properties of the small proline-rich 1 family of cornified cell envelope proteins. Integration with loricrin, J Biol Chem, 274, 7226, 10.1074/jbc.274.11.7226 Chirgwin, 1979, Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease, Biochemistry, 18, 5294, 10.1021/bi00591a005 Cuvillier, 1996, Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate, Nature, 381, 800, 10.1038/381800a0 Di Nardo, 2000, Ceramide 2 (N-acetyl sphingosine) is associated with reduction in Bcl-2 protein levels by Western blotting and with apoptosis in cultured human keratinocytes, Br J Dermatol, 143, 491, 10.1111/j.1365-2133.2000.03700.x Hannun, 2001, Enzymes of sphingolipid metabolism: From modular to integrative signaling, Biochemistry, 40, 4893, 10.1021/bi002836k Harris, 1997, Permeability barrier disruption coordinately regulates mRNA levels for key enzymes of cholesterol, fatty acid, and ceramide synthesis in the epidermis, J Invest Dermatol, 109, 783, 10.1111/1523-1747.ep12340962 Harris, 1998, Expression and regulation of mRNA for putative fatty acid transport related proteins and fatty acyl CoA synthase in murine epidermis and cultured human keratinocytes, J Invest Dermatol, 111, 722, 10.1046/j.1523-1747.1998.00383.x van Helvoort, 1996, MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine, Cell, 87, 507, 10.1016/S0092-8674(00)81370-7 Herrmann, 2003, Mice with targeted disruption of the fatty acid transport protein 4 (FATP4, Slc27a4) gene show features of lethal restrictive dermopathy, J Cell Biol, 161, 1105, 10.1083/jcb.200207080 Jarvis, 1996, Ceramide and the induction of apoptosis, Clin Cancer Res, 2, 1 Jensen, 1999, Roles for tumor necrosis factor receptor p55 and sphingomyelinase in repairing the cutaneous permeability barrier, J Clin Invest, 104, 1761, 10.1172/JCI5307 Kaminski, 2000, Identification of a novel human sterol-sensitive ATP-binding cassette transporter (ABCA7), Biochem Biophys Res Commun, 273, 532, 10.1006/bbrc.2000.2954 Klucken, 2000, ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport, Proc Natl Acad Sci USA, 97, 817, 10.1073/pnas.97.2.817 Kolesnick, 1999, Ceramide and apoptosis, Trends Biochem Sci, 24, 224, 10.1016/S0968-0004(99)01408-5 König, 1999, Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance, Biochim Biophys Acta, 1461, 377, 10.1016/S0005-2736(99)00169-8 Kreder, 1999, Impaired neutral sphingomyelinase activation and cutaneous barrier repair in FAN-deficient mice, EMBO J, 18, 2472, 10.1093/emboj/18.9.2472 Langmann, 1999, Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): Evidence for sterol-dependent regulation in macrophages, Biochem Biophys Res Commun, 257, 29, 10.1006/bbrc.1999.0406 Le Saux, 2000, Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum, Nat Genet, 25, 223, 10.1038/76102 Lee, 1999, Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate, Cell, 99, 301, 10.1016/S0092-8674(00)81661-X Liebisch, 1999, Quantitative measurement of different ceramide species from crude cellular extracts by electrospray ionization tandem mass spectrometry (ESI-MS/MS), J Lipid Res, 40, 1539, 10.1016/S0022-2275(20)33398-8 Menon, 1992, Lamellar bodies as delivery systems of hydrolytic enzymes: Implications for normal and abnormal desquamation, Br J Dermatol, 126, 337, 10.1111/j.1365-2133.1992.tb00675.x Mosser, 1993, Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters, Nature, 361, 726, 10.1038/361726a0 Orso, 2000, Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice, Nat Genet, 24, 192, 10.1038/72869 Ringpfeil, 2000, Pseudoxanthoma elasticum: Mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter, Proc Natl Acad Sci USA, 97, 6001, 10.1073/pnas.100041297 Robinson, 1997, S100A11, S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes, J Biol Chem, 272, 12035, 10.1074/jbc.272.18.12035 Schaffer, 1994, Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein, Cell, 79, 427, 10.1016/0092-8674(94)90252-6 Schmitz, 2001, ABC transporters and cholesterol metabolism, Front Biosci, 6, 505, 10.2741/A622 Schmitz, 2000, ABC transporters in cellular lipid trafficking, Curr Opin Lipidol, 11, 493, 10.1097/00041433-200010000-00007 Schmuth, 2000, Permeability barrier disorder in Niemann-Pick disease: Sphingomyelin-ceramide processing required for normal barrier homeostasis, J Invest Dermatol, 115, 459, 10.1046/j.1523-1747.2000.00081.x Schurer, 2001, Skin lipids, 27 Szakacs, 2001, Characterization of the ATPase cycle of human ABCA1: Implications for its function as a regulator rather than an active transporter, Biochem Biophys Res Commun, 288, 1258, 10.1006/bbrc.2001.5905 Tarcsa, 1998, Structural and transglutaminase substrate properties of the small proline-rich 2 family of cornified cell envelope proteins, J Biol Chem, 273, 23297, 10.1074/jbc.273.36.23297 Uchida, 2000, Epidermal sphingomyelins are precursors for selected stratum corneum ceramides, J Lipid Res, 41, 2071, 10.1016/S0022-2275(20)32369-5 Yamano, 2001, ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells, FEBS Lett, 508, 221, 10.1016/S0014-5793(01)03056-3