Regulation of nitric oxide and soluble guanylyl cyclase

Brain Research Bulletin - Tập 62 - Trang 505-515 - 2004
Joshua S. Krumenacker1, Khalid A. Hanafy1, Ferid Murad1
1Department of Integrative Biology and Pharmacology, Institute of Molecular Medicine, University of Texas Houston Medical School, 6431 Fannin Street, Houston, TX 77030, USA

Tài liệu tham khảo

Ashman, 1963, Isolation of adenosine 3′:5′ monophosphate and guanosine 3′:5′-monophosphate from rat urine, Biochem. Biophys. Res. Commun., 11, 330, 10.1016/0006-291X(63)90566-7 Aszodi, 1999, The vasodilator-stimulated phosphoprotein (VASP) is involved in cGMP- and cAMP-mediated inhibition of agonist-induced platelet aggregation, but is dispensable for smooth muscle function, EMBO J., 18, 37, 10.1093/emboj/18.1.37 Azam, 1998, Genetic mapping of soluble guanylyl cyclase genes: implications for linkage to blood pressure in the Dahl rat, Hypertension, 32, 149, 10.1161/01.HYP.32.1.149 Balabanli, 1999, Requirements for heme and thiols for the nonenzymatic modification of nitrotyrosine, Proc. Natl. Acad. Sci. U.S.A., 9, 13136, 10.1073/pnas.96.23.13136 Balciuniene, 1995, A gene for autosomal dominant progressive cone dystrophy (CORD5) maps to chromosome 17p12-p13, Genomics, 30, 281, 10.1006/geno.1995.9876 Beckman, 1996, Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and the ugly, Am. J. Physiol., 271, C1424, 10.1152/ajpcell.1996.271.5.C1424 Behrends, 1995, A variant of the alpha 2 subunit of soluble guanylyl cyclase contains an insert homologous to a region within adenylyl cyclases and functions as a dominant negative protein, J. Biol. Chem., 270, 21109, 10.1074/jbc.270.36.21109 Behrends, 1999, Assignment of GUCY1B2, the gene coding for the beta2 subunit of human guanylyl cyclase to chromosomal band 13q14.3 between markers D13S168 and D13S155, Genomics, 55, 126, 10.1006/geno.1998.5613 Behrends, 2000, Expression of nitric oxide-sensitive guanylyl cyclase subunits in human corpus cavernosum, Biochem. Pharmacol., 59, 713, 10.1016/S0006-2952(99)00381-0 Biel, 1999, Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3, Proc. Natl. Acad. Sci. U.S.A., 96, 7553, 10.1073/pnas.96.13.7553 Bloch, 1997, Pulmonary soluble guanylate cyclase, a nitric oxide receptor, is increased during the perinatal period, Am. J. Physiol., 272, L400 Boolell, 1996, Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction, Int. J. Impot. Res., 8, 47 Bredt, 1992, Nitric oxide, a novel neuronal messenger, Neuron, 8, 3, 10.1016/0896-6273(92)90104-L Budworth, 1999, Tissue distribution of the human soluble guanylate cyclases, Biochem. Biophys. Res. Commun., 263, 696, 10.1006/bbrc.1999.1444 Buechler, 1991, Expression of soluble guanylate cyclase activity requires both enzyme subunits, Biochem. Biophys. Res. Commun., 174, 351, 10.1016/0006-291X(91)90527-E Caccone, 1999, Characterization of the soluble guanylyl cyclase beta-subunit gene in the mosquito Anopheles gambiae, Insect. Mol. Biol., 8, 23, 10.1046/j.1365-2583.1999.810023.x Chhajlani, 1991, Heterogeneity in human soluble guanylate cyclase due to alternative splicing, FEBS Lett., 290, 157, 10.1016/0014-5793(91)81248-7 Crepel, 1990, Protein kinases, nitric oxide and long-term depression of synapses in the cerebellum, Neuroreport, 1, 133, 10.1097/00001756-199010000-00013 Davis, 2001, Novel effects of nitric oxide, Annu. Rev. Pharmacol. Toxicol., 41, 203, 10.1146/annurev.pharmtox.41.1.203 Deguchi, 1982, l-Arginine identified as an endogenous activator for soluble guanylate cyclase from neuroblastoma cells, J. Biol. Chem., 257, 10147, 10.1016/S0021-9258(18)33996-6 Deng, 1994, Genetic mapping of two new blood pressure quantitative trait loci in the rat by genotyping endothelin system genes, J. Clin. Invest., 93, 2701, 10.1172/JCI117284 Deng, 1994, Mapping of a quantitative trait locus for blood pressure on rat chromosome 2, J. Clin. Invest., 94, 431, 10.1172/JCI117341 Deng, 1997, Congenic strains for the blood pressure quantitative trait locus on rat chromosome 2, Hypertension, 30, 199, 10.1161/01.HYP.30.2.199 Endo, 1999, Molecular identification of human G-substrate, a possible downstream component of the cGMP-dependent protein kinase cascade in cerebellar Purkinje cells, Proc. Natl. Acad. Sci. U.S.A., 96, 2467, 10.1073/pnas.96.5.2467 Fedele, 1999, In vivo studies of the cerebral glutamate receptor/NO/cGMP pathway, Prog. Neurobiol., 58, 89, 10.1016/S0301-0082(98)00077-X Filippov, 1997, Nitric oxide decreases stability of mRNAs encoding soluble guanylate cyclase subunits in rat pulmonary artery smooth muscle cells, J. Clin. Invest., 100, 942, 10.1172/JCI119610 Foerster, 1996, A functional heme-binding site of soluble guanylyl cyclase requires intact N-termini of alpha 1 and beta 1 subunits, Eur. J. Biochem., 240, 380, 10.1111/j.1432-1033.1996.0380h.x Friebe, 1998, Mechanism of YC-1-induced activation of soluble guanylyl cyclase, Mol. Pharmacol., 53, 123, 10.1124/mol.53.1.123 Friebe, 1997, Functions of conserved cysteines of soluble guanylyl cyclase, Biochemistry, 36, 1194, 10.1021/bi962047w B. Gaston, J.S. Stamler, Biochemistry of Nitric Oxide, Nitric Oxide and Infection, Kluwer Academic/Plenum Publishers, Dordrecht/New York, 1999, pp. 37–55. Gibbs, 1998, Nitric oxide and cyclic GMP regulate retinal patterning in the optic lobe of Drosophila, Neuron, 20, 83, 10.1016/S0896-6273(00)80436-5 Giuili, 1993, Colocalization of the genes coding for the alpha 3 and beta 3 subunits of soluble guanylyl cyclase to human chromosome 4 at q31.3-q33a, Hum. Genet., 91, 91257, 10.1007/BF00218267 Gow, 1996, Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation, FEBS Lett., 385, 63, 10.1016/0014-5793(96)00347-X Guimaraes, 2001, Paracrine neuroprotective effect of nitric oxide in the developing retina, J. Neurochem., 76, 1233, 10.1046/j.1471-4159.2001.00126.x Gupta, 1997, The beta2 subunit inhibits stimulation of the alpha1/beta1 form of soluble guanylyl cyclase by nitric oxide. Potential relevance to regulation of blood pressure, J. Clin. Invest., 100, 1488, 10.1172/JCI119670 Hanafy, 2001, NO, nitrotyrosine and cGMP in signal transduction, Med. Sci. Monit., 7, 801 Hardman, 1969, Guanylyl cyclase, an enzyme catalyzing the formation of guanosine 3′,5′-monophosphate from guanosine triphosphate, J. Biol. Chem., 244, 6363, 10.1016/S0021-9258(18)63473-8 Harteneck, 1991, Molecular cloning and expression of a new alpha-subunit of soluble guanylyl cyclase. Interchangeability of the alpha-subunits of the enzyme, FEBS Lett., 292, 217, 10.1016/0014-5793(91)80871-Y Haynes, 2000, Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells, Circ. Res., 87, 677, 10.1161/01.RES.87.8.677 Hibbs, 1987, Macrophage cytotoxicity: role for l-arginine deiminase and imino nitrogen oxidation to nitrite, Science, 235, 473, 10.1126/science.2432665 Hobbs, 1997, Soluble guanylate cyclase: the forgotten sibling, Trends Pharmacol. Sci., 18, 484, 10.1016/S0165-6147(97)90687-8 Hughes, 1998, Fine localisation of the gene for central areolar choroidal dystrophy on chromosome 17p, J. Med. Genet., 35, 770, 10.1136/jmg.35.9.770 Huie, 1993, The reaction of NO with superoxide, Free Radic. Res. Commun., 18, 195, 10.3109/10715769309145868 Humbert, 1990, Purification of soluble guanylyl cyclase from bovine lung by a new immunoaffinity chromatographic method, Eur. J. Biochem., 190, 273, 10.1111/j.1432-1033.1990.tb15572.x Idriss, 1999, Nitric oxide regulation of gene transcription via soluble guanylate cyclase and type I cGMP-dependent protein kinase, J. Biol. Chem., 274, 9489, 10.1074/jbc.274.14.9489 Ignarro, 1982, Activation of purified guanylate cyclase by nitric oxide requires heme. Comparison of heme-deficient heme-reconstituted and heme-containing forms of soluble enzyme from bovine lung, Biochim. Biophys. Acta, 718, 49, 10.1016/0304-4165(82)90008-3 Itoh, 1998, Pregnancy increases soluble and particulate guanylate cyclases and decreases the clearance receptor of natriuretic peptides in ovine uterine, but not systemic, arteries, Endocrinology, 139, 3329, 10.1210/en.139.7.3329 Jarchau, 1994, Cloning, expression, and in situ localization of rat intestinal cGMP-dependent protein kinase II, Proc. Natl. Acad. Sci. U.S.A., 91, 9426, 10.1073/pnas.91.20.9426 Kamisaki, 1986, Soluble guanylate cyclase from rat lung exists as a heterodimer, J. Biol. Chem., 261, 7236, 10.1016/S0021-9258(17)38380-1 Kamisaki, 1998, An activity in rat tissues that modifies nitrotyrosine-containing proteins, Proc. Natl. Acad. Sci. U.S.A., 29, 11584, 10.1073/pnas.95.20.11584 Katsuki, 1977, Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine, J. Cyclic Nucleotide Res., 3, 23 Kelly, 2001, Rapid actions of plasma membrane estrogen receptors, Trends Endocrinol. Metab., 12, 12152, 10.1016/S1043-2760(01)00377-0 Kelsell, 1998, Mutations in the retinal guanylate cyclase (RETGC-1) gene in dominant cone-rod dystrophy, Hum. Mol. Genet., 7, 1179, 10.1093/hmg/7.7.1179 Kimura, 1975, Activation of guanylate cyclase from rat liver and other tissues by sodium azide, J. Biol. Chem., 250, 8016, 10.1016/S0021-9258(19)40809-0 Kimura, 1975, Two forms of guanylate cyclase in mammalian tissues and possible mechanisms for their regulation, Metabolism, 24, 439, 10.1016/0026-0495(75)90123-7 Kishimoto, 1996, The heart communicates with the kidney exclusively through the guanylyl cyclase-A receptor: acute handling of sodium and water in response to volume expansion, Proc. Natl. Acad. Sci. U.S.A., 93, 6215, 10.1073/pnas.93.12.6215 Klatt, 1999, Nitric oxide inhibits c-Jun DNA binding by specifically targeted S-glutathionylation, J. Biol. Chem., 274, 15857, 10.1074/jbc.274.22.15857 Kloss, 2000, Aging and chronic hypertension decrease expression of rat aortic soluble guanylyl cyclase, Hypertension, 35, 43, 10.1161/01.HYP.35.1.43 Koesling, 1999, Studying the structure and regulation of soluble guanylyl cyclase, Methods, 19, 485, 10.1006/meth.1999.0891 Kojima, 1995, A new type soluble guanylyl cyclase, which contains a kinase-like domain: its structure and expression, Biochem. Biophys. Res. Commun., 217, 993, 10.1006/bbrc.1995.2868 Komalavilas, 1994, Phosphorylation of the inositol 1,4,5-trisphosphate receptor by cyclic GMP-dependent protein kinase, J. Biol. Chem., 269, 8701, 10.1016/S0021-9258(17)37024-2 Koss, 1999, Functional role of nitric oxide in regulation of ocular blood flow, Eur. J. Pharmacol., 374, 161, 10.1016/S0014-2999(99)00242-3 Krumenacker, 2001, Estradiol rapidly inhibits soluble guanylyl cyclase expression in rat uterus, Proc. Natl. Acad. Sci. U.S.A., 98, 717, 10.1073/pnas.98.2.717 Krupinski, 1989, Adenylyl cyclase amino acid sequence: possible channel- or transporter-like structure, Science, 244, 1558, 10.1126/science.2472670 Lacaille, 1989, Electrophysiological and morphological characterization of hippocampal interneurons, The Hippocampus-New Vistas, 52, 287 Lander, 1995, Nitric oxide-stimulated guanine nucleotide exchange on p21ras, J. Biol. Chem., 270, 7017, 10.1074/jbc.270.13.7017 Lee, 2000, Human recombinant soluble guanylyl cyclase: expression, purification, and regulation, Proc. Natl. Acad. Sci. U.S.A., 97, 10763, 10.1073/pnas.190333697 Lincoln, 1995, cGMP signaling through cAMP- and cGMP-dependent protein kinases, Adv. Pharmacol., 34, 305, 10.1016/S1054-3589(08)61094-7 Liu, 1997, Nerve growth factor decreases soluble guanylate cyclase in rat pheochromocytoma PC12 cells, J. Biol. Chem., 272, 6038, 10.1074/jbc.272.9.6038 Liu, 2001, A metabolic enzyme for S-nitrosothiol conserved from bacteria to humans, Nature, 410, 490, 10.1038/35068596 Lohmann, 1997, Distinct and specific functions of cGMP-dependent protein kinases, Trends Biochem. Sci., 22, 307, 10.1016/S0968-0004(97)01086-4 Lopez, 1995, Salt-resistant hypertension in mice lacking the guanylyl cyclase-A receptor for atrial natriuretic peptide, Nature, 378, 65, 10.1038/378065a0 Lucas, 2000, Guanylyl cyclases and signaling by cyclic GMP, Pharmacol. Rev., 52, 375 Mann, 1997, Mice lacking the guanylyl cyclase C receptor are resistant to STa-induced intestinal secretion, Biochem. Biophys. Res. Commun., 239, 463, 10.1006/bbrc.1997.7487 Marletta, 1994, Nitric oxide synthase: aspects concerning structure and catalysis, Cell, 78, 927, 10.1016/0092-8674(94)90268-2 Matthews, 1996, Inhibition of NF-κB DNA binding by nitric oxide, Nucleic Acids Res., 24, 2236, 10.1093/nar/24.12.2236 Mikami, 1999, Tandem organization of medaka fish soluble guanylyl cyclase alpha1 and beta1 subunit genes. Implications for coordinated transcription of two subunit genes, J. Biol. Chem., 274, 18567, 10.1074/jbc.274.26.18567 Nakane, 1990, Molecular cloning and expression of cDNAs coding for soluble guanylate cyclase from rat lung, J. Biol. Chem., 265, 16841, 10.1016/S0021-9258(17)44837-X Nakane, 1988, Molecular cloning of a cDNA coding for 70 kilodalton subunit of soluble guanylate cyclase from rat lung, Biochem. Biophys. Res. Commun., 157, 1139, 10.1016/S0006-291X(88)80992-6 Nathan, 1992, Nitric oxide as a secretory product of mammalian cells, FASEB J., 6, 3051, 10.1096/fasebj.6.12.1381691 Nathan, 1994, Nitric oxide synthases: roles, tolls, and controls, Cell, 78, 915, 10.1016/0092-8674(94)90266-6 Nathanson, 1995, Alterations of ocular nitric oxide synthase in human glaucoma, Invest. Ophthalmol. Vis. Sci., 36, 1774 Neufeld, 1998, New conceptual approaches for pharmacological neuroprotection in glaucomatous neuronal degeneration, J. Glaucoma, 7, 434, 10.1097/00061198-199812000-00014 Neufeld, 1997, Nitric oxide synthase in the human glaucomatous optic nerve head, Arch. Ophthalmol., 115, 497, 10.1001/archopht.1997.01100150499009 Neufeld, 1999, Inhibition of nitric-oxide synthase 2 by aminoguanidine provides neuroprotection of retinal ganglion cells in a rat model of chronic glaucoma, Proc. Natl. Acad. Sci. U.S.A., 96, 9944, 10.1073/pnas.96.17.9944 Nighorn, 1999, Identification and characterization of a novel beta subunit of soluble guanylyl cyclase that is active in the absence of a second subunit and is relatively insensitive to nitric oxide, J. Biol. Chem., 274, 2525, 10.1074/jbc.274.4.2525 Oliver, 1997, Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A, Proc. Natl. Acad. Sci. U.S.A., 94, 14730, 10.1073/pnas.94.26.14730 Orstavik, 1996, Molecular cloning, cDNA structure, and chromosomal localization of the human type II cGMP-dependent protein kinase, Biochem. Biophys. Res. Commun., 220, 759, 10.1006/bbrc.1996.0477 Papapetropoulos, 1995, Regulation of vascular smooth muscle soluble guanylate cyclase activity, mRNA, and protein levels by cAMP-elevating agents, Hypertension, 26, 696, 10.1161/01.HYP.26.4.696 Perrault, 1996, Retinal-specific guanylate cyclase gene mutations in Leber’s congenital amaurosis, Nat. Genet., 14, 461, 10.1038/ng1296-461 Pollock, 1991, Purification and characterization of particulate EDRF synthase from cultured and native bovine aortic endothelial cells, Proc. Natl. Acad. Sci. U.S.A., 88, 10480, 10.1073/pnas.88.23.10480 Pryzwansky, 1995, Cyclic guanosine monophosphate-dependent protein kinase is targeted to intermediate filaments and phosphorylates vimentin in A23187-stimulated human neutrophils, Blood, 85, 222, 10.1182/blood.V85.1.222.bloodjournal851222 Quigley, 1994, Risk factors for the development of glaucomatous visual field loss in ocular hypertension, Arch. Ophthalmol., 112, 644, 10.1001/archopht.1994.01090170088028 Raeymaekers, 1990, Effects of cyclic nucleotide dependent protein kinases on the endoplasmic reticulum Ca2+ pump of bovine pulmonary artery, Cell Calcium, 11, 261, 10.1016/0143-4160(90)90002-C Rapoport, 1983, Endothelium-dependent and nitrovasodilator-induced relaxation of vascular smooth muscle: role of cyclic GMP, J. Cyclic Nucleotide Protein Phosphorylation Res., 9, 281 Ritter, 2000, Alternative splicing for the alpha1 subunit of soluble guanylate cyclase, Biochem. J., 346, 811, 10.1042/0264-6021:3460811 Ruetten, 1999, Downregulation of soluble guanylyl cyclase in young and aging spontaneously hypertensive rats, Circ. Res., 85, 534, 10.1161/01.RES.85.6.534 Russwurm, 1998, Functional properties of a naturally occurring isoform of soluble guanylyl cyclase, Biochem. J., 335, 125, 10.1042/bj3350125 A. Savchenko, T.W. Kraft, E. Molokanova, R.H. Kramer, Growth factors regulate phototransduction in retinal rods by modulating cyclic nucleotide-gated channels through dephosphorylation of a specific tyrosine residue, Proc. Natl. Acad. Sci. U.S.A. (2001) (epub ahead of print). Schmidt, 1994, NO at work, Cell, 78, 919, 10.1016/0092-8674(94)90267-4 Schoser, 2001, Soluble guanylyl cyclase is localized at the neuromuscular junction in human skeletal muscle, Neuroreport, 12, 979, 10.1097/00001756-200104170-00023 Schulz, 1997, Disruption of the guanylyl cyclase-C gene leads to a paradoxical phenotype of viable but heat-stable enterotoxin-resistant mice, J. Clin. Invest., 100, 1590, 10.1172/JCI119683 Schuman, 1994, Nitrovasodilator effects on intraocular pressure and outflow facility in monkeys, Exp. Eye Res., 58, 99, 10.1006/exer.1994.1199 Scott, 1998, Escherichia coli lipopolysaccharide downregulates soluble guanylate cyclase in pulmonary artery smooth muscle, J. Surg. Res., 80, 309, 10.1006/jsre.1998.5442 Shareef, 1999, Isoforms of nitric oxide synthase in the optic nerves of rat eyes with chronic moderately elevated intraocular pressure, Invest. Ophthalmol. Vis. Sci., 40, 2884 Sharina, 2000, Genomic organization of alpha1 and beta1 subunits of the mammalian soluble guanylyl cyclase genes, Proc. Natl. Acad. Sci. U.S.A., 97, 10878, 10.1073/pnas.190331697 Shimouchi, 1993, cAMP regulates soluble guanylate cyclase beta 1-subunit gene expression in RFL-6 rat fetal lung fibroblasts, Am. J. Physiol., 265, L456 Simpson, 1999, Identification of a novel guanylyl cyclase that is related to receptor guanylyl cyclases, but lacks extracellular and transmembrane domains, J. Biol. Chem., 274, 4440, 10.1074/jbc.274.7.4440 Sloviter, 1991, Feedforward and feedback inhibition of hippocampal principal cell activity evoked by perforant path stimulation: GABA-mediated mechanisms that regulate excitability in vivo, Hippocampus, 1, 31, 10.1002/hipo.450010105 Stasch, 2001, NO-independent regulatory site on soluble guanylate cyclase, Nature, 410, 212, 10.1038/35065611 Stone, 1994, Soluble guanylate cyclase from bovine lung: activation with nitric oxide and carbon monoxide and spectral characterization of the ferrous and ferric states, Biochemistry, 33, 5636, 10.1021/bi00184a036 Sunahara, 1998, Exchange of substrate and inhibitor specificities between adenylyl and guanylyl cyclases, J. Biol. Chem., 273, 16332, 10.1074/jbc.273.26.16332 Surks, 1999, Regulation of myosin phosphatase by a specific interaction with cGMP-dependent protein kinase Ialpha, Science, 286, 1583, 10.1126/science.286.5444.1583 Takata, 2001, Cytokines decrease sGC in pulmonary artery smooth muscle cells via NO-dependent and NO-independent mechanisms, Am. J. Physiol. Lung Cell. Mol. Physiol., 280, L272, 10.1152/ajplung.2001.280.2.L272 Tamura, 1996, cDNA cloning and gene expression of human type Ialpha cGMP-dependent protein kinase, Hypertension, 27, 552, 10.1161/01.HYP.27.3.552 Thorpe, 1989, The membrane form of guanylate cyclase. Homology with a subunit of the cytoplasmic form of the enzyme, J. Biol. Chem., 264, 6545, 10.1016/S0021-9258(18)83382-8 Uhler, 1993, Cloning and expression of a novel cyclic GMP-dependent protein kinase from mouse brain, J. Biol. Chem., 268, 13586, 10.1016/S0021-9258(19)38689-2 Varol, 2000, Nerve growth factor (NGF) and NGF mRNA change in rat uterus during pregnancy, Neurosci. Lett., 294, 58, 10.1016/S0304-3940(00)01533-0 Viner, 1999, Protein modification during biological aging: selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle, Biochem. J., 340, 657, 10.1042/0264-6021:3400657 Walter, 1989, Physiological role of cGMP and cGMP-dependent protein kinase in the cardiovascular system, Rev. Physiol. Biochem. Pharmacol., 113, 42 Wedel, 2001, The guanylyl cyclase family at y2k, Annu. Rev. Physiol., 63, 215, 10.1146/annurev.physiol.63.1.215 Wedel, 1995, Functional domains of soluble guanylyl cyclase, J. Biol. Chem., 270, 24871, 10.1074/jbc.270.42.24871 Wedel, 1994, Mutation of His-105 in the beta 1 subunit yields a nitric oxide-insensitive form of soluble guanylyl cyclase, Proc. Natl. Acad. Sci. U.S.A., 91, 2592, 10.1073/pnas.91.7.2592 Wiederholt, 1994, Relaxation of trabecular meshwork and ciliary muscle by release of nitric oxide, Invest. Ophthalmol. Vis. Sci., 35, 2515 Wilson, 1995, Identification of sequences mediating guanylyl cyclase dimerization, Biochemistry, 34, 4696, 10.1021/bi00014a025 Xu, 1998, Activation of the cardiac calcium release channel (ryanodine receptor) by poly-S-nitrosylation, Science, 279, 234, 10.1126/science.279.5348.234 Yamakura, 1998, Inactivation of human manganese-superoxide dismutase by peroxynitrite is caused by exclusive nitration of tyrosine 34 to 3-nitrotyrosine, J. Biol. Chem., 273, 14085, 10.1074/jbc.273.23.14085 Yuen, 1990, A new form of guanylyl cyclase is preferentially expressed in rat kidney, Biochemistry, 29, 10872, 10.1021/bi00501a002 Zabel, 1999, Homodimerization of soluble guanylyl cyclase subunits. Dimerization analysis using a glutathione S-transferase affinity tag, J. Biol. Chem., 274, 18149, 10.1074/jbc.274.26.18149 Zhao, 2000, Inhibition of soluble guanylate cyclase by ODQ, Biochemistry, 39, 10848, 10.1021/bi9929296 Zhuo, 1995, Long-term depression: a learning-related type of synaptic plasticity in the mammalian central nervous system, Rev. Neurosci., 6, 259, 10.1515/REVNEURO.1995.6.3.259 Zou, 1998, Interleukin 1beta decreases prostacyclin synthase activity in rat mesangial cells via endogenous peroxynitrite formation, Biochem. J., 336, 507, 10.1042/bj3360507