1College of Medicine, Department of Internal Medicine, Division of Digestive Diseases and Nutrition, 800 Rose Street, MN649A-0298, University of Kentucky, Lexington, KY 40536, USA
2School of Medicine, Department of Pharmacology and Toxicology, 500 South Preston Street, University of Louisville, Louisville, KY 40292, USA
3Cleveland Clinic Foundation, Department of Biostatistics and Epidemiology, 9500 Euclid Avenue, OH 44196, USA
4School of Medicine, Department of Medicine, Division of Gastroenterology/Hepatology, 550 South Jackson Street, University of Louisville, Louisville, KY 40292, USA