Effects of nonionic surfactants on membrane transporters in Caco-2 cell monolayers

Badary, 1998, Effect of Cremophor EL on the pharmacokinetics, antitumor activity and toxicity of doxorubicin in mice, Anticancer Drugs, 9, 809, 10.1097/00001813-199810000-00011 Brandsch, 1994, Expression and protein kinase C-dependent regulation of peptide/H+ co-transport system in the Caco-2 human colon carcinoma cell line, Biochem. J., 299, 253, 10.1042/bj2990253 Castro, 1999, Mechanism of inhibition of P-glycoprotein-mediated drug transport by protein kinase C blockers, Biochem. Pharmacol., 58, 1723, 10.1016/S0006-2952(99)00288-9 Chang, 1996, The effect of water-soluble vitamin E on cyclosporine pharmacokinetics in healthy volunteers, Clin. Pharmacol. Ther., 59, 297, 10.1016/S0009-9236(96)80007-5 Chervinsky, 1993, Reversal of C1300 murine neuroblastoma multidrug resistance by cremophor EL, a solvent for cyclosporin A, Cancer Biother., 8, 67, 10.1089/cbr.1993.8.67 Davis, 1970, Normal and promoted gastrointestinal absorption of water-soluble substances. I. Induced rapidly reversible hyperabsorptive state in the canine fundic stomach pouch, J. Pharm. Sci., 59, 960, 10.1002/jps.2600590708 Dudeja, 1995, Reversal of multidrug resistance phenotype by surfactants: relationship to membrane lipid fluidity, Arch. Biochem. Biophys., 319, 309, 10.1006/abbi.1995.1298 Germann, 1995, Effects of phosphorylation of P-glycoprotein on multidrug resistance, J. Bioenerg. Biomembr., 27, 53, 10.1007/BF02110331 Hu, 1995, Mechanisms of transport of quinapril in Caco-2 cell monolayers: comparison with cephalexin, Pharm. Res., 12, 1120, 10.1023/A:1016247523311 Koga, 1998, Effects of fatty acid sucrose esters on ceftibuten transport by rat intestinal brush-border membrane vesicles, Biol. Pharm. Bull., 21, 747, 10.1248/bpb.21.747 Koga, 1999, Effects of fatty acid glycerol esters on intestinal absorptive and secretory transport of ceftibuten, Biol. Pharm. Bull., 22, 402, 10.1248/bpb.22.402 Koga, 1999, Modification of ceftibuten transport by changes in lipid fluidity caused by fatty acid glycerol esters, Biol. Pharm. Bull., 22, 103, 10.1248/bpb.22.103 Koga, 2000, Modification of ceftibuten transport by the addition of non-ionic surfactants, Eur. J. Pharm. Biopharm., 49, 17, 10.1016/S0939-6411(99)00059-4 Lebo, 1995, Modulation of membrane cholesterol content in cultured LLC-PK1 cells, Int. J. Pharm., 125, 1, 10.1016/0378-5173(95)00095-Z Lee, 1999, Modulation of sulfate renal transport by alterations in cell membrane fluidity, J. Pharm. Sci., 88, 976, 10.1021/js990114c Lentz, 2000, Influence of passive permeability on apparent P-glycoprotein kinetics, Pharm. Res., 17, 1456, 10.1023/A:1007692622216 Miller, 1999, Inhibition of multidrug resistance-associated protein (MRP) functional activity with pluronic block copolymers, Pharm. Res., 16, 396, 10.1023/A:1018873702411 Mountfield, 2000, Potential inhibitory effects of formulation ingredients on intestinal cytochrome P450, Int. J. Pharm., 211, 89, 10.1016/S0378-5173(00)00586-X Nabekura, 1996, Modulation of organic cation transport and lipid fluidity by benzyl alcohol in rat renal brush-border membranes, Pharm. Res., 13, 1069, 10.1023/A:1016066926269 Nerurkar, 1996, The use of surfactants to enhance the permeability of peptides through Caco-2 cells by inhibition of an apically polarized efflux system, Pharm. Res., 13, 528, 10.1023/A:1016033702220 Nerurkar, 1997, Mechanistic roles of neutral surfactants on concurrent polarized and passive membrane transport of a model peptide in Caco-2 cells, J. Pharm. Sci., 86, 813, 10.1021/js960483y Polli, 1999, Role of P-glycoprotein on the CNS disposition of amprenavir (141W94), an HIV protease inhibitor, Pharm. Res., 16, 1206, 10.1023/A:1018941328702 Rege, 2001, Effect of common excipients on Caco-2 transport of low permeability drugs, J. Pharm. Sci., 90, 1776, 10.1002/jps.1127 Saeki, 1992, Specific drug binding by purified lipid-reconstituted P-glycoprotein: dependence on the lipid composition, Biochim. Biophys. Acta, 1107, 105, 10.1016/0005-2736(92)90334-I Sinicrope, 1992, Modulation of P-glycoprotein-mediated drug transport by alterations in lipid fluidity of rat liver canalicular membrane vesicles, J. Biol. Chem., 267, 24995, 10.1016/S0021-9258(19)73996-9 Sokol, 1991, Improvement of cyclosporin absorption in children after liver transplantation by means of water-soluble vitamin E, Lancet, 338, 212, 10.1016/0140-6736(91)90349-T Sparreboom, 1997, Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine, Proc. Natl. Acad. Sci. USA, 94, 2031, 10.1073/pnas.94.5.2031 Thwaites, 1993, Transepithelial glycylsarcosine transport in intestinal Caco-2 cells mediated by expression of H(+)-coupled carriers at both apical and basal membranes, J. Biol. Chem., 268, 7640, 10.1016/S0021-9258(18)53004-0 Thwaites, 1993, H(+)-coupled dipeptide (glycylsarcosine) transport across apical and basal borders of human intestinal Caco-2 cell monolayers display distinctive characteristics, Biochim. Biophys. Acta, 1151, 237, 10.1016/0005-2736(93)90108-C Troutman, 2001, P-glycoprotein (P-gp) is not responsible for the inability of rhodamine 123 to enter Caco-2 cells across apical membrane during absorptive transport, AAPSPharmSci., 3 Tsuji, 1994, Transcellular transport of benzoic acid across Caco-2 cells by a pH-dependent and carrier-mediated transport mechanism, Pharm. Res., 11, 30, 10.1023/A:1018933324914 van Heeswijk, 2001, Combination of protease inhibitors for the treatment of HIV-1-infected patients: a review of pharmacokinetics and clinical experience, Antivir. Ther., 6, 201, 10.1177/135965350200600401 Woodcock, 1992, Reversal of multidrug resistance by surfactants, Br. J. Cancer, 66, 62, 10.1038/bjc.1992.217 Wu, 2000, Atorvastatin transport in the Caco-2 cell model: contributions of P-glycoprotein and the proton-monocarboxylic acid co-transporter, Pharm. Res., 17, 209, 10.1023/A:1007525616017 Yu, 1999, Vitamin E-TPGS increases absorption flux of an HIV protease inhibitor by enhancing its solubility and permeability, Pharm. Res., 16, 1812, 10.1023/A:1018939006780 Yumoto, 1999, Transport of rhodamine 123, a P-glycoprotein substrate, across rat intestine and Caco-2 cell monolayers in the presence of cytochrome P-450 3A-related compounds, J. Pharmacol. Exp. Ther., 289, 149 Zhao, 1989, Cremophor EL, a widely used parenteral vehicle, is a potent inhibitor of protein kinase C, Biochem. Biophys. Res. Commun., 159, 1359, 10.1016/0006-291X(89)92260-2