Distribution of Macrolide-Resistance Genes in Staphylococcus aureus Blood-Culture Isolates from Fifteen German University Hospitals

European Journal of Clinical Microbiology and Infectious Diseases - Tập 19 - Trang 385-387 - 2000
F.-J. Schmitz1, J. Petridou2, A. C. Fluit1, U. Hadding2, G. Peters3, C. von Eiff3
1Eijkman-Winkler Institute for Clinical Microbiology, Utrecht Medical Center, University of Utrecht, The Netherlands, , NL
2Institute for Medical Microbiology and Virology, Heinrich-Heine-Universität Düsseldorf, Universitätsstraße 1, Geb. 22.21, 40225 Düsseldorf, Germany e-mail: [email protected], , DE
3Institute of Medical Microbiology, Westfälische Wilhelms University Münster, Germany, , DE

Tóm tắt

 The purpose of the study was to analyze the distribution of the macrolide-resistance genes in 134 erythromycin-resistant Staphylococcus aureus blood-culture isolates collected at 15 German university hospitals. The most prevalent resistance gene was ermC (68/134; 50.7%), followed by ermA (52/134; 38.8%), ereB (10/134; 7.5%), and mrsA/msrB (4/134; 6%). The least common genes were ermB (3/134; 2.2%) and ereA (1/134; 0.7%). Overall, resistance to erythromycin was predominantly due to the presence of two erm genes, although with different distributions, depending on the methicillin-resistance pattern.

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European Journal of Clinical Microbiology and Infectious Diseases

Tập 19

385-387

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