Morphological studies by light and electron microscopy of pancreatic acinar cells under the effect of Tityus serrulatus venom

Springer Science and Business Media LLC - Tập 278 Số 2 - Trang 255-264 - 1994
Maryann D. Fletcher1, Lourival D. Possani2, Paul L. Fletcher1
1Department of Microbiology and Immunology, East Carolina University School of Medicine, Greenville, USA
2Departmento de Bioquimica, Instituto de Biotecnologia, National Autonomous University of Mexico, Av., Cuernavaca, Mexico

Tóm tắt

Từ khóa


Tài liệu tham khảo

Adler G, Hupp T, Kern HT (1979) Course and spontaneous regression of acute pancreatitis in the rat. Virchows Arch [A] 382:31–47

Aho HJ, Nevalainen TJ, Havia VT, Heinonen RJ, Aho AJ (1982) Human acute pancreatitis: A light and electron microscopic study. Acta Pathol Microbiol Immunol Scand Sect A 90:367–373

Bartholomew C (1970) Acute scorpion pancreatitis in Trinidad. Br Med J 1:666–668

Bernfeld P (1955) Amylases, α and β. In: Colowick SP, Kaplan NO (eds) Methods in enzymology, vol I. Academic Press, New York, pp 149–158

Bohm GM, Pompolo S, Diniz CR, Gomez MV, Pimenta AF, Netto JC (1974) Ultrastructural alterations of mouse diaphragm nerve endings induced by purified scorpion venom tityustoxin. Toxicon 12:509–511

Corrado AP, Neto FR, Antonio A (1974) The mechanism of the hypertensive effect of Brazilian scorpion venom (Tityus serrulatus Lutz and Mello). Toxicon 12:145–150

Diniz CR (1971) Clinical and pharmacological properties of Tityus venoms. In: Bucherl W, Buckley EE (eds) Venomous animals and their venoms. Venomous invertebrates, vol III. Academic Press, New York, pp 311–315

Fletcher PL Jr, Fletcher MD, Possani LD (1992) Characteristics of pancreatic exocrine secretion procuced by venom from the Brazilian scorpion Tityus serrulatus. Eur J Cell Biol 58:259–270

Freire-Maia L, Azevedo AD, Costa Val VP (1973) Respiratory arrhythmias produced by purified scorpion toxin. Toxicon 11:255–257

Freire-Maia L, Pinto GI, Franco I (1974) Mechanism of the cardiovascular effects produced by purified scorpion toxin in the rat. J Pharmacol Exper Ther 188:207–213

Rreire-Maia L, Azevedo AD, Lima EG (1976 a) Pharmacological blockade of the cardiovascular and respiratory effects produced by Tityustoxin in the rat. In: Ohsaka A, Hayashi K, Sawai Y (eds) Animal plant and microbial toxins, vol 2. Plenum Press, New York, pp 287–298

Freire-Maia L, Cunha-Melo JR, Futuro-Neto HA, Azevedo AD, Weinberg J (1976 b) Cholinergic and adrenergic effects of Tityustoxin. Gen Pharmacol 7:115–121

Freire-Maia L, Cunha-Melo JR, Gomez MV, Maria TA, Calixto SL, Futuro-Neto HA (1976 c) Studies on the mechanism of action of Tityustoxin. In: Ohsaka A, Hayashi K, Sawai Y (eds) Animal plant and microbial toxins, vol 2. Plenum Press, New York, pp 273–285

Hendricks LC, McCaffery M, Palade GE, Farquhar MG (1993) Disruption of endoplasmic reticulum to Golgi transport leads to the accumulation of large aggregates containing β-COP in pancreatic acinar cells. Mol Biol Cell 4:413–424

Kloppel G, Dreyer T, Willemer S, Kern H, Adler G (1986) Human acute pancreatitis: its pathogenesis in the light of immunocytochemical and ultrastructural findings in acinar cells. Virchows Arch [A] 409:791–803

Kulka RG, Sternlicht E (1968) Enzyme secretion in mouse pancreas mediated by adenosine-3′5′-cyclic phosphate and inhibited by adenosine-3′-phosphate. Proc Natl Acad Sci USA 61:1123–1128

Lampel M, Kern H (1977) Acute interstitial pancreatitis in the rat induced by excessive doses of a pancreatic secretagogue. Virchows Arch [A] 373:97–117

Lima EG, Almeida HO, Gomez MV, Freire-Maia L (1975) Acute pulmonary edema induced by injection of Tityustoxin into the lateral ventricles of rats. Toxicon 13:205–206

Machado JC, Silveira JF da (1977) Induction of acute hemornhagic pancreatitis in dog by escorpionic venom of T. serrulatus. Mem Inst Butantan 40/41:1–9

Merisko EM, Fletcher M, Palade GE (1986) The reorganization of the Golgi complex in anoxic pancreatic cells. Pancreas 1:95–109

Novaes G, Catanzaro OL, Beraldo WT, Freire-Maia L (1982) Effect of purified scorpion toxin (Tityustoxin) on the pancreatic secretion of the rat. Toxicon 20:847–853

Oprins A, Duden R, Kreis TE, Geuze HJ, Slot JW (1993) β-COP localizes mainly to the cis-Golgi side in exocrine pancreas. J Cell Biol 121:49–59

Pantoja JL, Renner IG, Abramson SB, Edmonson HA (1983) Production of acute hemorrhagic pancreatitis in the dog using venom of the scorpion Buthus quinquestriatus. Dig Dis Sci 28:429–439

Poon-King T (1963) Myocarditis from scorpion stings. Br Med J 1:374

Possani LD (1984) Structure of scorpion toxins. In: Tu AT (ed) Handbook of natural toxins, vol II. Marcel Dekker, New York, pp 513–550

Possani LD, Alagon AC, Fletcher PL Jr, Erickson BW (1977) Purification and properties of mammalian toxins from the venom of the Brazilian scorpion Tityus serrulatus Lutz and Mello. Arch Biochem Biophys 180:394–403

Possani LD, Martin BM, Fletcher MD, Fletcher PL Jr (1991) Discharge effect on pancreatic exocrine secretion produced by toxins purified from Tityus serrulatus scorpion venom. J Biol Chem 266:3178–3185

Rossi MA, Ferreira AL, Paiva SM (1974) Fine structures of pulmonary changes induced by Brazilian scorpion venom. Arch Pathol 97:284–288

Scheele GA, Palade GE (1975) Studies on the guinea pig pancreas. Parallel discharge of exocrine enzyme activities. J Biol Chem 250:2660–2770

Scheele G, Adler G, Kern H (1987) Exocytosis occurs at the lateral plasma membrane of the pancreatic acinar cell during supramaximal secretagogue stimulation. Gastroenterology 92:345–353

Sofer S, Shalev H, Weizman Z, Shahak E, Gueron M (1991) Acute pancreatitis in children following envenomation by the yellow scorpion Leiurus quinquestriatus. Toxicon 29:125–128

Tafuri WL, Maria TA, Freire-Maia L, Cunha-Melo JR (1974) Effect of the scorpion toxin on the granular vesicles in the Auerbach's plexus of the rat ileum. J Neural Trans 35:233–240

Vincent D, Bauduin H (1972) Influence of cerulein on the secretion and metabolism of the rat exocrine pancreas in vitro. Biol Gastroenterol 5:85–90

Watanabe O, Baccino FM, Steer ML, Meldolesi J (1984) Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: early morphological changes during development of experimental pancreatitis. Am J Physiol 246:G457–467

Waterman JA (1938) Some notes on scorpion poisoning in Trinidad. Trans R Soc Trop Med Hyg 31:607–624