1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor

Bioorganic & Medicinal Chemistry Letters - Tập 11 - Trang 1907-1910 - 2001
Roderick A Porter1, Wai N Chan1, Steven Coulton1, Amanda Johns1, Michael S Hadley1, Katherine Widdowson2, Jeffrey C Jerman1, Stephen J Brough1, Martyn Coldwell1, Darren Smart1, Frances Jewitt1, Phillip Jeffrey3, Nigel Austin3
1GlaxoSmithKline Pharmaceuticals, New Frontiers Science Park North, Third Avenue, Harlow, Essex CM19 5AW, UK
2GlaxoSmithKline Pharmaceuticals, King of Prussia, PA 19406, USA
3GlaxoSmithKline Pharmaceuticals, The Frythe, Welwyn, Herts AL6 9AR, UK

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