Combination of biomarkers to predict mortality in elderly patients with myocardial infarction

Anderson, 2005, Candidate-based proteomics in the search for biomarkers of cardiovascular disease, J. Physiol., 563, 23, 10.1113/jphysiol.2004.080473 Antonicelli, 2005, Tumor necrosis factor-alpha gene −308G>A polymorphism is associated with ST-elevation myocardial infarction and with high plasma levels of biochemical ischemia markers, Coron. Artery Dis., 16, 489, 10.1097/00019501-200512000-00006 Antonicelli, 2005, The interleukin-6 −174 G>C promoter polymorphism is associated with an higher risk of death after an acute coronary syndrome in male elderly patients, Int. J. Cardiol., 103, 266, 10.1016/j.ijcard.2004.08.064 Austin, 2007, A comparison of regression trees, logistic regression, generalized additive models, and multivariate adaptive regression splines for predicting AMI mortality, Stat. Med., 26, 2937, 10.1002/sim.2770 Bathum, 2007, Methylenetetrahydrofolate reductase 677C>T and methionine synthase 2756A>G mutations: no impact on survival, cognitive functioning, or cognitive decline in nonagenarians, J. Gerontol. A Biol. Sci. Med. Sci., 62, 196, 10.1093/gerona/62.2.196 Beckman, 2005, Comparison of usefulness of inflammatory markers in patients with versus without peripheral arterial disease in predicting adverse cardiovascular outcomes (myocardial infarction, stroke, and death), Am. J. Cardiol., 96, 1374, 10.1016/j.amjcard.2005.07.041 Bertrand, 2002, Task Force on the Management of Acute Coronary Syndromes of the European Society of Cardiology Management of acute coronary syndromes in patients presenting without persistent ST-segment elevation, Eur. Heart J., 23, 1809, 10.1053/euhj.2002.3385 Bonaa, 2006, NORVIT Trial Investigators, 2006. Homocysteine lowering and cardiovascular events after acute myocardial infarction, N. Engl. J. Med., 354, 1578 Concato, 1993, The risk of determining risk with multivariable models, Ann. Intern. Med., 118, 201, 10.7326/0003-4819-118-3-199302010-00009 Cummings, 2006, Combining serum biomarkers: the association of C-reactive protein, insulin sensitivity, and homocysteine with cardiovascular disease history in the general US population, Eur. J. Cardiovasc. Prev. Rehabil., 13, 180, 10.1097/01.hjr.0000185973.59512.d3 Dickens, 2007, Depression is a risk factor for mortality after myocardial infarction: fact or artifact?, J. Am. Coll. Cardiol., 49, 1834, 10.1016/j.jacc.2007.01.075 European Society of Hypertension-European Society of Cardiology Guidelines and Committee, European Society of Hypertension-European Society of Cardiology Guidelines Committee. 2003 European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension. J. Hypertens. 21, 1011–1053. Fletcher, 2006, Update on exercise stress testing, Am. Fam. Phys., 74, 1749 Foussas, 2005, Early prognostic usefulness of C-reactive protein added to the Thrombolysis in Myocardial Infarction risk score in acute coronary syndromes, Am. J. Cardiol., 96, 533, 10.1016/j.amjcard.2005.04.015 Franceschi, 2000, Inflamm-aging. An evolutionary perspective on immunosenescence, Ann. N.Y. Acad. Sci., 908, 244, 10.1111/j.1749-6632.2000.tb06651.x Franceschi, 2007, Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans, Mech. Ageing Dev., 128, 92, 10.1016/j.mad.2006.11.016 Giacconi, 2004, The −174G/C polymorphism of IL-6 is useful to screen old subjects at risk for atherosclerosis or to reach successful ageing, Exp. Gerontol., 39, 621, 10.1016/j.exger.2003.12.013 Giacconi, 2006, Involvement of −308 TNF-alpha and 1267 Hsp70-2 polymorphisms and zinc status in the susceptibility of coronary artery disease (CAD) in old patients, Biogerontology, 7, 347, 10.1007/s10522-006-9049-3 Girelli, 2006, Hyperhomocysteinemia and mortality after coronary artery bypass grafting, PLoS ONE, 20, e83, 10.1371/journal.pone.0000083 Gori, 2005, A proinflammatory state is associated with hyperhomocysteinemia in the elderly, Am. J. Clin. Nutr., 82, 335, 10.1093/ajcn/82.2.335 Gruenewald, 2006, Combinations of biomarkers predictive of later life mortality, Proc. Natl. Acad. Sci. U.S.A., 103, 14158, 10.1073/pnas.0606215103 Hultdin, 2004, Elevated plasma homocysteine: cause or consequence of myocardial infarction?, J. Intern. Med., 256, 491, 10.1111/j.1365-2796.2004.01415.x Kammersgaard, 2006, Cardiovascular risk factors and 5-year mortality in the Copenhagen Stroke Study, Cerebrovasc. Dis., 21, 187, 10.1159/000090531 Kass, 1980, An exploratory technique for investigating large quantities of categorical data, Appl. Stat., 29, 119, 10.2307/2986296 Klerk, 2002, MTHFR Studies Collaboration Group. MTHFR 677C→T polymorphism and risk of coronary heart disease: a meta-analysis, JAMA, 288, 2023, 10.1001/jama.288.16.2023 Lange, 2006, Association of polymorphisms in the CRP gene with circulating C-reactive protein levels and cardiovascular events, JAMA, 296, 2703, 10.1001/jama.296.22.2703 Laupacis, 1990, The cost-effectiveness of routine post myocardial infarction exercise stress testing, Can. J. Cardiol., 6, 157 Lee, 2006, Relative value of multiple plasma biomarkers as risk factors for coronary artery disease and death in an angiography cohort, CMAJ, 174, 461, 10.1503/cmaj.050880 Lonn, 2006, Heart Outcomes Prevention Evaluation (HOPE) 2 Investigators Homocysteine lowering with folic acid and B vitamins in vascular disease, N. Engl. J. Med., 354, 1567, 10.1056/NEJMoa060900 Lowe, 2006, The association between elevated levels of inflammation biomarkers and coronary artery disease and death, CMAJ, 174, 479, 10.1503/cmaj.060054 Lowe, 2005, Circulating inflammatory markers and risks of cardiovascular and non-cardiovascular disease, J. Thromb. Haemost., 3, 1618, 10.1111/j.1538-7836.2005.01416.x McDade, 2006, Psychosocial and behavioral predictors of inflammation in middle-aged and older adults: the Chicago health, aging, and social relations study, Psychosom. Med., 68, 376, 10.1097/01.psy.0000221371.43607.64 Malavolta, 2004, New trends in biomedical aging research, Gerontology, 50, 420, 10.1159/000080182 Mager, 2005, Family history, plasma homocysteine, and age at onset of symptoms of myocardial ischemia in patients with different methylenetetrahydrofolate reductase genotypes, Am. J. Cardiol., 95, 1420, 10.1016/j.amjcard.2005.01.097 Palazzuoli, 2006, Brain natriuretic peptide and other risk markers for outcome assessment in patients with non-ST-elevation coronary syndromes and preserved systolic function, Am. J. Cardiol., 98, 1322, 10.1016/j.amjcard.2006.06.023 Pearson, 2003, Centers for Disease Control and Prevention; American Heart Association. 2003. Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association, Circulation, 107, 499, 10.1161/01.CIR.0000052939.59093.45 Pearte, 2006, Characteristics and baseline clinical predictors of future fatal versus nonfatal coronary heart disease events in older adults: the Cardiovascular Health Study, Circulation, 113, 2177, 10.1161/CIRCULATIONAHA.105.610352 Ranjit, 2007, Psychosocial factors and inflammation in the multi-ethnic study of atherosclerosis, Arch. Intern. Med., 167, 174, 10.1001/archinte.167.2.174 Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus, 1997. Diabetes Care 20, 1183–1197. Roest, 2001, Methylenetetrahydrofolate reductase 677 C/T genotype and cardiovascular disease mortality in postmenopausal women, Am. J. Epidemiol., 153, 673, 10.1093/aje/153.7.673 Rossi, 2006, Hyperhomocysteinemia predicts total and cardiovascular mortality in high-risk women, J. Hypertens., 24, 851, 10.1097/01.hjh.0000222754.75196.5c Rozanski, 2005, The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice: the emerging field of behavioral cardiology, J. Am. Coll. Cardiol., 45, 637, 10.1016/j.jacc.2004.12.005 Schmaltz, 2007, Living alone, patient sex and mortality after acute myocardial infarction, J. Gen. Intern. Med., 22, 572, 10.1007/s11606-007-0106-7 Stork, 2006, Prediction of mortality risk in the elderly, Am. J. Med., 119, 519, 10.1016/j.amjmed.2005.10.062 Sun, 2005, Methylenetetrahydrofolate reductase polymorphism associated with susceptibility to coronary heart disease in Chinese type 2 diabetic patients, Mol. Cell. Endocrinol., 229, 95, 10.1016/j.mce.2004.09.003 Tuomisto, 2006, C-reactive protein, interleukin-6 and tumor necrosis factor alpha as predictors of incident coronary and cardiovascular events and total mortality. A population-based, prospective study, Thromb. Haemost., 95, 511, 10.1160/TH05-08-0571 Weikert, 2005, A homocysteine metabolism-related dietary pattern and the risk of coronary heart disease in two independent German study populations, J. Nutr., 135, 1981, 10.1093/jn/135.8.1981 Zee, 2007, Homocysteine, 5,10-methylenetetrahydrofolate reductase 677C>T polymorphism, nutrient intake, and incident cardiovascular disease in 24,968 initially healthy women, Clin. Chem., 53, 845, 10.1373/clinchem.2006.083881