Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition

Cell Host & Microbe - Tập 29 - Trang 44-57.e9 - 2021
Allison J. Greaney1,2, Tyler N. Starr, Pavlo Gilchuk3, Seth J. Zost3, Elad Binshtein3, Andrea N. Loes1,4, Sarah K. Hilton1, John Huddleston5, Rachel Eguia1, Katharine H.D. Crawford1,2, Adam S. Dingens1, Rachel S. Nargi3, Rachel E. Sutton3, Naveenchandra Suryadevara3, Paul W. Rothlauf6,7, Zhuoming Liu6, Sean P.J. Whelan6, Robert H. Carnahan4,8, James E. Crowe4,8,9, Jesse D. Bloom1,2,4
1Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
2Department of Genome Sciences & Medical Scientist Training Program, University of Washington, Seattle, WA 98195, USA
3Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA
4Howard Hughes Medical Institute, Seattle, WA 98109 USA
5Molecular and Cell Biology, University of Washington, Seattle, WA 98195 USA
6Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA
7Program in Virology, Harvard Medical School, Boston, MA 02115, USA
8Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA
9Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA

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