T-cell regulation by CD4 regulatory T cells during hepatitis B and C virus infections: facts and controversies
Tài liệu tham khảo
Rehermann, 2005, Immunology of hepatitis B virus and hepatitis C virus infection, Nat Rev Immunol, 5, 215, 10.1038/nri1573
Wieland, 2005, Stealth and cunning: hepatitis B and hepatitis C viruses, J Virol, 79, 9369, 10.1128/JVI.79.15.9369-9380.2005
Rollier, 2007, Vaccine-induced early control of hepatitis C virus infection in chimpanzees fails to impact on hepatic PD-1 and chronicity, Hepatology, 45, 602, 10.1002/hep.21573
Dolganiuc, 2003, Hepatitis C virus core and nonstructural protein 3 proteins induce pro- and anti-inflammatory cytokines and inhibit dendritic cell differentiation, J Immunol, 170, 5615, 10.4049/jimmunol.170.11.5615
Kanto, 1999, Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals, J Immunol, 162, 5584, 10.4049/jimmunol.162.9.5584
Sarobe, 2002, Abnormal priming of CD4(+) T cells by dendritic cells expressing hepatitis C virus core and E1 proteins [erratum in J Virol 2004; 138: 193], J Virol, 76, 5062, 10.1128/JVI.76.10.5062-5070.2002
Shevach, 2006, The lifestyle of naturally occurring CD4+ CD25+ FOXP3+ regulatory T cells, Immunol Rev, 212, 60, 10.1111/j.0105-2896.2006.00415.x
Zhao, 2006, Activated CD4+CD25+ T cells selectively kill B lymphocytes, Blood, 107, 3925, 10.1182/blood-2005-11-4502
Ghiringhelli, 2006, The role of regulatory T cells in the control of natural killer cells: relevance during tumor progression, Immunol Rev, 214, 229, 10.1111/j.1600-065X.2006.00445.x
La Cava, 2006, CD4+CD25+ Tregs and NKT cells: regulators regulating regulators, Trends Immunol, 27, 322, 10.1016/j.it.2006.05.003
Mahnke, 2005, Dendritic cells: key cells for the induction of regulatory T cells?, Curr Top Microbiol Immunol, 293, 133
Knoechel, 2005, Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen, J Exp Med, 202, 1375, 10.1084/jem.20050855
Sakaguchi, 2004, Naturally arising CD4+ regulatory T cells for immunologic self-tolerance and negative control of immune responses, Annu Rev Immunol, 22, 531, 10.1146/annurev.immunol.21.120601.141122
Itoh, 1999, Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance, J Immunol, 162, 5317, 10.4049/jimmunol.162.9.5317
Shimizu, 2002, Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance, Nat Immunol, 3, 135, 10.1038/ni759
Baecher-Allan, 2004, Suppressor T cells in human diseases, J Exp Med, 200, 273, 10.1084/jem.20040812
Jonuleit, 2001, Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood, J Exp Med, 193, 1285, 10.1084/jem.193.11.1285
Thornton, 1998, CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production, J Exp Med, 188, 287, 10.1084/jem.188.2.287
Shevach, 2006, From vanilla to 28 flavors: multiple varieties of T regulatory cells, Immunity, 25, 195, 10.1016/j.immuni.2006.08.003
Bluestone, 2003, Natural versus adaptive regulatory T cells, Nat Rev Immunol, 3, 253, 10.1038/nri1032
Roncarolo, 2006, Interleukin-10-secreting type 1 regulatory T cells in rodents and humans, Immunol Rev, 212, 28, 10.1111/j.0105-2896.2006.00420.x
Groux, 1997, A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis, Nature, 389, 737, 10.1038/39614
Kitani, 2000, Activated self-MHC-reactive T cells have the cytokine phenotype of Th3/T regulatory cell 1 T cells, J Immunol, 165, 691, 10.4049/jimmunol.165.2.691
Lewkowich, 2005, CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function, J Exp Med, 202, 1549, 10.1084/jem.20051506
Cederbom, 2000, CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells, Eur J Immunol, 30, 1538, 10.1002/1521-4141(200006)30:6<1538::AID-IMMU1538>3.0.CO;2-X
Veldhoen, 2006, Modulation of dendritic cell function by naive and regulatory CD4+ T cells, J Immunol, 176, 6202, 10.4049/jimmunol.176.10.6202
Houot, 2006, Human CD4+CD25high regulatory T cells modulate myeloid but not plasmacytoid dendritic cells activation, J Immunol, 176, 5293, 10.4049/jimmunol.176.9.5293
Kryczek, 2006, Cutting edge: induction of B7-H4 on APCs through IL-10: novel suppressive mode for regulatory T cells, J Immunol, 177, 40, 10.4049/jimmunol.177.1.40
Cortesini, 2002, Tailoring of immunosuppression in renal and liver allograft recipients displaying donor specific T-suppressor cells, Hum Immunol, 63, 1010, 10.1016/S0198-8859(02)00442-1
Fallarino, 2003, Modulation of tryptophan catabolism by regulatory T cells, Nat Immunol, 4, 1206, 10.1038/ni1003
Cottrez, 2001, Regulation of TGF-beta response during T cell activation is modulated by IL-10, J Immunol, 167, 773, 10.4049/jimmunol.167.2.773
Kitani, 2003, Transforming growth factor (TGF)-β1-producing regulatory T cells induce SMAD-mediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-β1-mediated fibrosis, J Exp Med, 198, 1179, 10.1084/jem.20030917
Jonuleit, 2002, Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells, J Exp Med, 196, 255, 10.1084/jem.20020394
Barrat, 2002, In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines, J Exp Med, 195, 603, 10.1084/jem.20011629
Gregori, 2005, An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells, J Exp Med, 201, 1293, 10.1084/jem.20040912
Wakkach, 2001, Differentiation of regulatory T cells 1 is induced by CD2 costimulation, J Immunol, 167, 3107, 10.4049/jimmunol.167.6.3107
Levings, 2001, IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells, J Immunol, 166, 5530, 10.4049/jimmunol.166.9.5530
Weiner, 2001, Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells, Immunol Rev, 182, 207, 10.1034/j.1600-065X.2001.1820117.x
Battaglia, 2006, Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance, Diabetes, 55, 40, 10.2337/diabetes.55.01.06.db05-0613
MacDonald, 2002, CD4 T helper type 1 and regulatory T cells induced against the same epitopes on the core protein in hepatitis C virus-infected persons, J Infect Dis, 185, 720, 10.1086/339340
Marshall, 2003, Regulatory T cells secreting IL-10 dominate the immune response to EBV latent membrane protein 1, J Immunol, 170, 6183, 10.4049/jimmunol.170.12.6183
Boussiotis, 2000, IL-10-producing T cells suppress immune responses in anergic tuberculosis patients, J Clin Invest, 105, 1317, 10.1172/JCI9918
Plebanski, 1999, Interleukin 10-mediated immunosuppression by a variant CD4 T cell epitope of Plasmodium falciparum, Immunity, 10, 651, 10.1016/S1074-7613(00)80064-3
Doetze, 2000, Antigen-specific cellular hyporesponsiveness in a chronic human helminth infection is mediated by T(h)3/T(r)1-type cytokines IL-10 and transforming growth factor-beta but not by a T(h)1 to T(h)2 shift, Int Immunol, 12, 623, 10.1093/intimm/12.5.623
Lohr, 2006, Regulatory T cells in the periphery, Immunol Rev, 212, 149, 10.1111/j.0105-2896.2006.00414.x
Hori, 2003, Control of regulatory T cell development by the transcription factor FOXP3, Science, 299, 1057, 10.1126/science.1079490
Bacchetta, 2006, Defective regulatory and effector T cell functions in patients with FOXP3 mutations, J Clin Invest, 116, 1713, 10.1172/JCI25112
Morgan, 2005, Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans, Hum Immunol, 66, 13, 10.1016/j.humimm.2004.05.016
Pillai, 2007, Transient regulatory T-cells: a state attained by all activated human T-cells, Clin Immunol, 123, 18, 10.1016/j.clim.2006.10.014
Wang, 2007, Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells, Eur J Immunol, 37, 129, 10.1002/eji.200636435
Walker, 2003, Induction of FOXP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells, J Clin Invest, 112, 1437, 10.1172/JCI19441
Roncador, 2005, Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level, Eur J Immunol, 35, 1681, 10.1002/eji.200526189
Gavin, 2006, Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development, Proc Natl Acad Sci USA, 103, 6659, 10.1073/pnas.0509484103
Allan, 2007, Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production, Int Immunol, 19, 345, 10.1093/intimm/dxm014
Yamagiwa, 2001, A role for TGF-β in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood, J Immunol, 166, 7282, 10.4049/jimmunol.166.12.7282
Zheng, 2007, IL-2 is essential for TGF-β to convert naive CD4+CD25− cells to CD25+FOXP3+ regulatory T cells and for expansion of these cells, J Immunol, 178, 2018, 10.4049/jimmunol.178.4.2018
Chen, 2003, Conversion of peripheral CD4+CD25− naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor FOXP3, J Exp Med, 198, 1875, 10.1084/jem.20030152
Tran, 2007, Induction of FOXP3 expression in naive human CD4+FOXP3− T cells by T cell receptor stimulation is TGFβ-dependent but does not confer a regulatory phenotype, Blood, 10.1182/blood-2007-06-094656
Lau, 2003, Dendritic cells and immune regulation in the liver, Gut, 52, 307, 10.1136/gut.52.2.307
Borsellino, 2007, Expression of ectonucleotidase CD39 by FOXP3+ Treg cells: hydrolysis of extracellular ATP and immune suppression, Blood, 110, 1225, 10.1182/blood-2006-12-064527
Liu, 2006, CD127 expression inversely correlates with FOXP3 and suppressive function of human CD4+ T reg cells, J Exp Med, 203, 1701, 10.1084/jem.20060772
Seddiki, 2006, Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells, J Exp Med, 203, 1693, 10.1084/jem.20060468
Golden-Mason, 2006, Loss of IL-7 receptor alpha-chain (CD127) expression in acute HCV infection associated with viral persistence, Hepatology, 44, 1098, 10.1002/hep.21365
Sugimoto, 2003, Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection, Hepatology, 38, 1437
Cabrera, 2004, An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection, Hepatology, 40, 1062, 10.1002/hep.20454
Boettler, 2005, T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection, J Virol, 79, 7860, 10.1128/JVI.79.12.7860-7867.2005
Rushbrook, 2005, Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection, J Virol, 79, 7852, 10.1128/JVI.79.12.7852-7859.2005
Manigold, 2006, FOXP3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C, Blood, 107, 4424, 10.1182/blood-2005-09-3903
Bolacchi, 2006, Increased hepatitis C virus (HCV)-specific CD4+CD25+ regulatory T lymphocytes and reduced HCV-specific CD4+ T cell response in HCV-infected patients with normal versus abnormal alanine aminotransferase levels, Clin Exp Immunol, 144, 188, 10.1111/j.1365-2249.2006.03048.x
Li, 2007, Defining target antigens for CD25+FOXP3+IFN-γ− regulatory T cells in chronic hepatitis C virus infection, Immunol Cell Biol, 85, 197, 10.1038/sj.icb.7100020
Farci, 2000, Clinical significance of hepatitis C virus genotypes and quasispecies, Semin Liver Dis, 20, 103
Cacciarelli, 1996, Immunoregulatory cytokines in chronic hepatitis C virus infection: pre- and posttreatment with interferon alfa, Hepatology, 24, 6, 10.1002/hep.510240102
Lechmann, 1999, Decreased frequency of HCV core-specific peripheral blood mononuclear cells with type 1 cytokine secretion in chronic hepatitis C, J Hepatol, 31, 971, 10.1016/S0168-8278(99)80307-9
Brady, 2003, Hepatitis C virus non-structural protein 4 suppresses Th1 responses by stimulating IL-10 production from monocytes, Eur J Immunol, 33, 3448, 10.1002/eji.200324251
Franzese, 2005, Modulation of the CD8+-T-cell response by CD4+ CD25+ regulatory T cells in patients with hepatitis B virus infection, J Virol, 79, 3322, 10.1128/JVI.79.6.3322-3328.2005
Stoop, 2005, Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection, Hepatology, 41, 771, 10.1002/hep.20649
Xu, 2006, Circulating and liver resident CD4+CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B, J Immunol, 177, 739, 10.4049/jimmunol.177.1.739
Kondo, 2006, Mechanism of T cell hyporesponsiveness to HBcAg is associated with regulatory T cells in chronic hepatitis B, World J Gastroenterol, 12, 4310, 10.3748/wjg.v12.i27.4310
Stoop, 2007, Inhibition of viral replication reduces regulatory T cells and enhances the antiviral immune response in chronic hepatitis B, Virology, 361, 141, 10.1016/j.virol.2006.11.018
Feng, 2007, HBcAg-specific CD4(+)CD25(+) regulatory T cells modulate immune tolerance and acute exacerbation on the natural history of chronic hepatitis B virus infection, J Biomed Sci, 14, 43, 10.1007/s11373-006-9129-z
Yang, 2007, Association of CD4+CD25+FOXP3+ regulatory T cells with chronic activity and viral clearance in patients with hepatitis B, Int Immunol, 19, 133, 10.1093/intimm/dxl130
Fu, 2006, The characterization of regulatory T cells in peripheral blood of HBV-infected patients, Zhonghua Yi Xue Za Zhi, 86, 1522
Hyodo, 2003, Frequencies of interferon-gamma and interleukin-10 secreting cells in peripheral blood mononuclear cells and liver infiltrating lymphocytes in chronic hepatitis B virus infection, Hepatol Res, 27, 109, 10.1016/S1386-6346(03)00199-2
Szkaradkiewicz, 2003, HBcAg-specific cytokine production by CD4 T lymphocytes of children with acute and chronic hepatitis B, Virus Res, 97, 127, 10.1016/j.virusres.2003.08.013
Taams, 2002, Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells, Eur J Immunol, 32, 1621, 10.1002/1521-4141(200206)32:6<1621::AID-IMMU1621>3.0.CO;2-Q
Kursar, 2002, Regulatory CD4+CD25+ T cells restrict memory CD8+ T cell responses, J Exp Med, 196, 1585, 10.1084/jem.20011347
Suvas, 2003, CD4+CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses, J Exp Med, 198, 889, 10.1084/jem.20030171
Toka, 2004, CD4+ CD25+ T cells regulate vaccine-generated primary and memory CD8+ T-cell responses against herpes simplex virus type 1, J Virol, 78, 13082, 10.1128/JVI.78.23.13082-13089.2004
Aandahl, 2004, Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens, J Virol, 78, 2454, 10.1128/JVI.78.5.2454-2459.2004
Kinter, 2004, CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status, J Exp Med, 200, 331, 10.1084/jem.20032069
Weiss, 2004, Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients, Blood, 104, 3249, 10.1182/blood-2004-01-0365
Dittmer, 2004, Functional impairment of CD8(+) T cells by regulatory T cells during persistent retroviral infection, Immunity, 20, 293, 10.1016/S1074-7613(04)00054-8
Beilharz, 2004, Timed ablation of regulatory CD4+ T cells can prevent murine AIDS progression, J Immunol, 172, 4917, 10.4049/jimmunol.172.8.4917
Brooks, 2005, Intrinsic functional dysregulation of CD4 T cells occurs rapidly following persistent viral infection, J Virol, 79, 10514, 10.1128/JVI.79.16.10514-10527.2005
Crispe, 2006, Cellular and molecular mechanisms of liver tolerance, Immunol Rev, 213, 101, 10.1111/j.1600-065X.2006.00435.x
Lee, 2005, Liver stellate cells suppress dendritic cells through IL-10, Transplant Proc, 37, 10, 10.1016/j.transproceed.2004.12.277
Pasare, 2003, Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells, Science, 299, 1033, 10.1126/science.1078231
Pasare, 2004, Toll-dependent control mechanisms of CD4 T cell activation, Immunity, 21, 733, 10.1016/j.immuni.2004.10.006
Lenardo, 1999, Mature T lymphocyte apoptosis—immune regulation in a dynamic and unpredictable antigenic environment, Annu Rev Immunol, 17, 221, 10.1146/annurev.immunol.17.1.221
Russell, 1991, Receptor-stimulated death pathway is opened by antigen in mature T cells, Proc Natl Acad Sci USA, 88, 2151, 10.1073/pnas.88.6.2151
Rouse, 2004, Regulatory cells and infectious agents: detentes cordiale and contraire, J Immunol, 173, 2211, 10.4049/jimmunol.173.4.2211
Tiegs, 1992, A T cell-dependent experimental liver injury in mice inducible by concanavalin A, J Clin Invest, 90, 196, 10.1172/JCI115836
Erhardt, 2007, IL-10, regulatory T cells, and Kupffer cells mediate tolerance in concanavalin A-induced liver injury in mice, Hepatology, 45, 475, 10.1002/hep.21498
Oswald-Richter, 2004, HIV infection of naturally occurring and genetically reprogrammed human regulatory T-cells, PLoS Biol, 2, e198, 10.1371/journal.pbio.0020198
Belkaid, 2002, CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity, Nature, 420, 502, 10.1038/nature01152
Wang, 2003, Virus-specific CD8 T cells in peripheral tissues are more resistant to apoptosis than those in lymphoid organs, Immunity, 18, 631, 10.1016/S1074-7613(03)00116-X
Chazouilleres, 1994, “Occult” hepatitis B virus as source of infection in liver transplant recipients, Lancet, 343, 142, 10.1016/S0140-6736(94)90934-2
Pham, 2004, Hepatitis C virus persistence after spontaneous or treatment-induced resolution of hepatitis C, J Virol, 78, 5867, 10.1128/JVI.78.11.5867-5874.2004
Zinkernagel, 2003, On natural and artificial vaccinations, Annu Rev Immunol, 21, 515, 10.1146/annurev.immunol.21.120601.141045