A review of the main bacterial fish diseases in mariculture systems

Aquaculture - Tập 246 - Trang 37-61 - 2005
Alicia E. Toranzo1, Beatriz Magariños1, Jesús L. Romalde1
1Departamento de Microbiología y Parasitología, Facultad de Biología and Instituto de Acuicultura, Universidad de Santiago de Compostela, 15782, Spain

Tài liệu tham khảo

Actis, 1999, Vibriosis, vol. 3, 523 Alday-Sanz, 1994, An immunohistochemical diagnostic test for rickettsial disease, J. Fish Dis., 17, 189, 10.1111/j.1365-2761.1994.tb00213.x Almendras, 1997, Salmonid rickettsial septicemia caused by Piscirickettsia salmonis: a review, Dis. Aquat. Org., 29, 137, 10.3354/dao029137 Amaro, 1996, Vibrio vulnifucus biotype 2, pathogenic for eels, is also an opportunistic pathogen for humans, Appl. Environ. Microbiol., 62, 1454, 10.1128/AEM.62.4.1454-1457.1996 Amaro, 1992, Comparative study of phenotypic and virulence properties in Vibrio vulnificus biotype 1 and 2 obtained from a European eel farm experiencing mortalities, Dis. Aquat. Org., 13, 29, 10.3354/dao013029 Arias, 1995, Nested PCR method for rapid and sensitive detection of Vibrio vulnificus in fish, sediments, and water, Appl. Environ. Microbiol., 61, 3476, 10.1128/AEM.61.9.3476-3478.1995 Arias, 1997, Intraspecific differentiation of Vibrio vulnificus biotypes by amplified fragment length polymorphism and ribotyping, Appl. Environ. Microbiol., 63, 2600, 10.1128/AEM.63.7.2600-2606.1997 Austin, 1996, Fish pathogens, 197 Austin, 1999 Avendaño-Herrera, 2004, Phenotypic characterization and description of two major O-serotypes in Tenacibaculum maritimum strains from marine fishes, Dis. Aquat. Org., 58, 1, 10.3354/dao058001 Avendaño-Herrera, 2004, Intraspecific diversity of the marine fish pathogen Tenacibaculum maritimum as determined by randomly amplified polymorphic DNA-PCR, J. Appl. Microbiol., 96, 871, 10.1111/j.1365-2672.2004.02217.x Avendaño-Herrera, 2004, Comparative evaluation of species-specific polymerase chain reaction primer sets for the routine identification of Tenacibaculum maritimum, Dis. Aquat. Org., 62, 75, 10.3354/dao062075 Aznar, 1993, Ribotyping and randomly amplified polymorphic DNA analysis of Vibrio vulnificus biotypes, Syst. Appl. Microbiol., 16, 303, 10.1016/S0723-2020(11)80484-4 Bachrach, 2001, Recovery of Streptococcus iniae from diseased fish previously vaccinated with a Streptococcus vaccine, Appl. Environ. Microbiol., 67, 3756, 10.1128/AEM.67.8.3756-3758.2001 Bader, 1998, Identification of Flavobacterium and Flexibacter species by species-species polymerase chain reaction primers to the 16S ribosomal RNA gene, J. Aquat. Anim. Health, 10, 311, 10.1577/1548-8667(1998)010<0311:IOFAFS>2.0.CO;2 Bakopoulos, 1997, Development of an ELISA to detect Pasteurella piscicida in cultured and ‘spiked’ fish tissue, Aquaculture, 156, 359, 10.1016/S0044-8486(97)00137-3 Bandín, 1993, Detection of a common antigen among Renibacterium salmoninarum, Corynebacterium aquaticum, and Carnobacterium piscicola by the Western blot technique, J. Aquat. Anim. Health, 5, 172, 10.1577/1548-8667(1993)005<0172:DOACAA>2.3.CO;2 Bandín, 1995, Effect of serum factors on the survival of Renibacterium salmoninarum within rainbow trout macrophages, Dis. Aquat. Org., 23, 221, 10.3354/dao023221 Bandín, 1996, Growth of the fish pathogen Renibacterium salmoninarum on different media, Microbiología (SEM), 12, 439 Bandín, 1996, Comparison of different ELISA Kits for detecting Renibacterium salmoninarum, Bull. Eur. Assoc. Fish Pathol., 16, 19 Barja, 2003, Posibilidades prácticas y limitaciones del control saniario en el salmón Atlantico. Actuaciones desde la Consellería de Medio Ambiente, 145 Bark, 2001, The first occurrence of lactococcosis in farmed trout in England, Trout News, 31, 9 Bast, 1988, Evaluation of profiles of Aeromonas salmonicida as epidemiological markers of furunculosis infections in fish, J. Fish Dis., 11, 133, 10.1111/j.1365-2761.1988.tb00533.x Beaz, 2003, Nuevos cebadores del gen fstA, receptor del complejo hierro-sideróforo para detectar Aeromonas salmonicida por PCR, 16 Benediktsdóttir, 1991, Incubation time for the cultivation of Renibacterium salmoninarum from Atlantic salmon, Salmo salar L., broodfish, J. Fish Dis., 14, 97, 10.1111/j.1365-2761.1991.tb00580.x Benediktsdóttir, 1998, Vibrio spp. isolated from salmonids with shallow skin lesions and reared at low temperature, J. Fish Dis., 21, 19, 10.1046/j.1365-2761.1998.00065.x Benediktsdóttir, 2000, Characterization of Vibrio viscosus and Vibrio wodanis isolated at different geographical locations: a proposal for reclassification of Vibrio viscosus as Moritella viscosa comb. nov., Int. J. Syst. Evol. Microbiol., 50, 479, 10.1099/00207713-50-2-479 Bercovier, 1997, Immunization with bacterial antigens: infections with streptococci and related organisms, 153 Bernadet, 1997, Immunization with bacterial antigens: Flavobacterium and Flexibacter infections, 179 Bernardet, 1989, Deoxyribonucleic acid relatedness and phenotypic characteristics of Flexibacter columnaris sp. nov. nom. rev. Flexibacter psychrophilus sp. nov. nom rev. and Flexibacter maritimus Wakabayashi, Hikida and Masamura, 1986, Int. J. Syst. Bacteriol., 39, 346, 10.1099/00207713-39-3-346 Bernoth, 1997, Furunculosis: the history of the disease and of disease research, 1 Berthe, 1995, Identification of Pseudomonas anguilliseptica isolated from several fish species in France, Dis. Aquat. Org., 21, 151, 10.3354/dao021151 Biosca, 1991, First record of Vibrio vulnificus biotype 2 from diseased European eel, Anguilla anguilla, L., J. Fish Dis., 14, 103, 10.1111/j.1365-2761.1991.tb00581.x Biosca, 1997, Phenotypic and genotypic characterization of Vibrio vulnificus: proposal for the substitution of the subspecific taxon for serovar, Appl. Environ. Microbiol., 63, 1460, 10.1128/AEM.63.4.1460-1466.1997 Birkbeck, 2002, Pasteurella skyensis sp. nov., isolated from Atlantic salmon (Salmo salar L.), Int. J. Syst. Evol. Microbiol., 52, 699, 10.1099/ijs.0.01884-0 Birrell, 2003, Piscirickettsia salmonis in farmed Atlantic salmon, Salmo salar in Scotland, Bull. Eur. Assoc. Fish Pathol., 23, 213 Blanco, 2002, PCR detection and PFGE DNA macrorestriction analysis of clinical isolates of Pseudomonas anguilliseptica from winter disease outbreaks in sea bream Sparus aurata, Dis. Aquat. Org., 50, 19, 10.3354/dao050019 Bragg, 1990, Mycobacterium fortuitum isolated from three species of fish in South Africa, Onderstepoort J. Vet. Res., 57, 101 Branson, 1991, Description of a new disease condition occurring in farmed coho salmon, Oncorhynchus kisutch (Walbaum), in South America, J. Fish Dis., 14, 147, 10.1111/j.1365-2761.1991.tb00585.x Bravo, 1994, Piscirickettsiosis in fresh water, Bull. Eur. Assoc. Fish Pathol., 14, 137 Bravo, 1989, Coho salmo syndrome in Chile, FHS/AFS Newsl., 17, 3 Bricknell, 1999, Susceptibility of halibut, Hippoglossus hippoglossus (L.), to infection with Aeromons salmonicida, Aquaculture, 175, 1, 10.1016/S0044-8486(99)00025-3 Bromage, 1999, Streptococcus iniae, a bacterial infection in barramundi Lates calcarifer, Dis. Aquat. Org., 36, 177, 10.3354/dao036177 Brown, 1994, Use of polymerase chain reaction (PCR) to detect DNA from Renibacterium salmoninarum within individual salmonid eggs, Dis. Aquat. Org., 18, 165, 10.3354/dao018165 Brown, 1995, Bacterial species other than Renibacterium salmoninarum cross-react with antisera against R. salmoninarum but are negative for the p57 gene of Renibacterium salmoninarum as detected by the polymerase chain reaction (PCR), Dis. Aquat. Org., 21, 227, 10.3354/dao021227 Bruno, 1986, Histopathology of bacterial kidney disease in laboratory infected rainbow trout, Salmo gaidneri (Richarson), and Atlantic salmon, Salmo salar L., with reference to naturally infected fish, J. Fish Dis., 9, 523, 10.1111/j.1365-2761.1986.tb01049.x Bruno, 1986, Observations on Renibacterium salmoninarum and the salmonid egg, Dis. Aquat. Org., 1, 83, 10.3354/dao001083 Bruno, 1986, Uniformity in the biochemical properties of Renibacterium salmoninarum isolates obtained from several sources, FEMS Microbiol. Lett., 33, 247, 10.1111/j.1574-6968.1986.tb01280.x Bruno, 1986, Histopathology, bacteriology and experimental transmission of a cold water vibriosis in Atlantic salmon Salmo salar, Dis. Aquat. Org., 1, 163, 10.3354/dao001163 Bruno, 1998, Vibrio viscosus in farmed Atlantic salmon Salmo salar in Scotland: field and experimental observations, Dis. Aquat. Org., 34, 161, 10.3354/dao034161 Bruno, 1998, Pathology attributed to Mycobacterium chelonae infection among farmed and laboratory-infected Atlantic salmon Salmo salar, Dis. Aquat. Org., 33, 101, 10.3354/dao033101 Chase, 1998, Development of a nested polymerase chain reaction for amplification of a sequence of the p57 gene of Renibacterium salmoninarum that provides a highly sensitive method for detection of the bacterium in salmonid kidney, Dis. Aquat. Org., 34, 223, 10.3354/dao034223 Chen, 1995, Isolation of Flexibacter maritimus from California, FHS/AFS Newsl., 22, 7 Chinabut, 1999, Mycobacteriosis and Nocardiosis, vol. 3, 319 Cipriano, 1992, Detection of Aeromonas salmonicida in the mucus of salmonid fish, J. Aquat. Anim. Health, 4, 114, 10.1577/1548-8667(1992)004<0114:DOASIT>2.3.CO;2 Cipriano, 1994, Evaluation of mucus as a valid site to isolate Aeromonas salmonicida among asymptomatic populations of lake trout (Salvelinus mamaycush), Biomed. Lett., 49, 229 Cipriano, 1996, Use of non-lethal procedures to detect and monitor Aeromonas salmonicida in potentially endangered or threatened populations of migrating and post-spawning salmon, Dis. Aquat. Org., 27, 233, 10.3354/dao027233 Coleman, 1996, Optimization of conditions for the polymerase chain reaction amplification of DNA from culturable and nonculturable cells of Vibrio vulnificus, FEMS Microbiol. Ecol., 19, 127, 10.1111/j.1574-6941.1996.tb00205.x Colorni, 1992, A systemic mycobacteriosis in the European seabass Dicentrarchus labrax cultured in Eilat (Red Sea), Isr. J. Aquac.-Bamidgeh, 44, 75 Colorni, 1993, Detection of mycobacteriosis in fish using the polymerase chain reaction technique, Bull. Eur. Assoc. Fish Pathol., 13, 195 Colorni, 1996, Epizootiology of Mycobacterium spp. in seabass, seabream and other commercial fish, 259 Colorni, 2002, Streptococcus iniae infections in red seacage-cultured and wild fishes, Dis. Aquat. Org., 49, 165, 10.3354/dao049165 Colorni, 2003, Lactococcus garvieae in wild red sea wrasse Coris aygula (Labriidae), Dis. Aquat. Org., 56, 275, 10.3354/dao056275 Comps, 1996, Rickettsia-like organism infecting juvenile sea-bass Dicentrarchus labrax, Bull. Eur. Assoc. Fish Pathol., 16, 30 Cook, 1999, A sensitive nested reverse transcriptase PCR-assay to detect viable cells of the fish pathogen Renibacterium salmoninarum in Atlantic salmon (Salmo salar L.), Appl. Environ. Microbiol., 65, 3042, 10.1128/AEM.65.7.3042-3047.1999 Cvitanich, 1991, The isolation of a Rickettsia-like organism causing disease and mortality in Chilean salmonids and its confirmation by Koch's postulate, J. Fish Dis., 14, 121, 10.1111/j.1365-2761.1991.tb00584.x Dalsgaard, 1998, Indole-positive Vibrio vulnificus isolated from outbreaks on a Danish eel farm, Dis. Aquat. Org., 35, 187, 10.3354/dao035187 Daly, 1993, Nutritional requirements of Renibacterium salmoninarum on agar and in broth media, Appl. Environ. Microbiol., 59, 2178, 10.1128/AEM.59.7.2178-2183.1993 Daly, 2001, Characterization of attenuated Renibacterium salmoninarum strains and their use as live vaccines, Dis. Aquat. Org., 44, 121, 10.3354/dao044121 Decostere, 2004, Piscine mycobacteriosis: a literature review covering the agent and the disease it causes in fish and humans, Vet. Microbiol., 99, 159, 10.1016/j.vetmic.2003.07.011 Devesa, 1989, Ulcerative and skin and fin lesions in reared turbot (Scophthalmus maximus L.), J. Fish Dis., 12, 323, 10.1111/j.1365-2761.1989.tb00321.x Diamant, 2000, Mycobacteriosis in wild rabbitfish Siganus rivulatus associated with cage farming in the Gulf of Eilat, Red Sea, Dis. Aquat. Org., 39, 211, 10.3354/dao039211 Doménech, 1996, Streptococcosis in cultured turbot, Scophthalmus maximus (L.), associated with Streptococcus parauberis, J. Fish Dis., 19, 33, 10.1111/j.1365-2761.1996.tb00117.x Doménech, 1997, Winter disease outbreak in sea bream (Sparus aurata) associated with Pseudomonas anguilliseptica infection, Aquaculture, 156, 317, 10.1016/S0044-8486(97)00069-0 dos Santos, 2002, Mycobacterial infection in farmed turbot Scophthalmus maximus, Dis. Aquat. Org., 52, 87, 10.3354/dao052087 Egidius, 1986, Vibrio salmonicida sp. nov., a new fish pathogen, Int. J. Syst. Bacteriol., 36, 518, 10.1099/00207713-36-4-518 Eldar, 1999, Lactococcus garvieae and Streptococcus iniae infections in rainbow trout Oncorhynchus mykiss: similar, but different diseases, Dis. Aquat. Org., 36, 227, 10.3354/dao036227 Eldar, 1995, Streptococcus shiloi, the name for an agent causing septicemic infection in fish, is a junior synonym of Streptococcus iniae, Int. J. Syst. Bacteriol., 45, 840, 10.1099/00207713-45-4-840 Eldar, 1996, Enterococcus seriolicida is a junior synonym of Lactococcus garvieae, a causative agent of septicemia and meningoencephalitis in fish, Curr. Microbiol., 32, 85, 10.1007/s002849900015 Eldar, 1997, Restriction fragment length polymorphisms of 16S rDNA and of whole rRNA genes (ribotyping) of Streptococcus iniae strains from the United States and Israel, FEMS Microbiol. Lett., 151, 155, 10.1111/j.1574-6968.1997.tb12564.x Eldar, 1997, Development and efficacy of a vaccine against Streptococcus iniae infection in farmed rainbow trout, Vet. Immunol. Immunopathol., 56, 175, 10.1016/S0165-2427(96)05738-8 Eldar, 1999, Biodiversity of Lactococcus garvieae isolated from fish in Europe, Asia, and Australia, Appl. Environ. Microbiol., 65, 1005, 10.1128/AEM.65.3.1005-1008.1999 Eldar, 1999, Red drum Sciaenops ocellatus mortalities associated with Streptococcus iniae infection, Dis. Aquat. Org., 36, 121, 10.3354/dao036121 Ellis, 1997, Immunization with bacterial antigens: furunculosis, 107 Enger, 1997, Survival and inactivation of Aeromonas salmonicida outside the host—a most superficial way of life, 159 Espelid, 1987, The specificity of Atlantic salmon antibodies made against the fish pathogen Vibrio salmonicida, establishing the surface protein VS-P1 as the predominant antigen, Dev. Comp. Immunol., 11, 529, 10.1016/0145-305X(87)90042-5 Esteve-Gassent, 2004, Efficacy of oral reimmunisation after immersion vaccination against Vibrio vulnificus in farmed European eels, Aquaculture, 231, 9, 10.1016/j.aquaculture.2003.10.006 Evelyn, 1977, An improved growth medium for the kidney disease bacterium and some notes using the medium, Bull.-Off. Int. Epizoot., 87, 511 Evelyn, 1993, Bacterial kidney diseases—BKD, 177 Evelyn, 1990, Two new techniques for obtaining consistent results when growing Renibacterium salmoninarum on KDM2 culture, Dis. Aquat. Org., 9, 209, 10.3354/dao009209 Evsenden, 1993, Renibacterium salmoninarum and bacterial kidney disease—the unfinished jigsaw, Annu. Rev. Fish Dis., 3, 87, 10.1016/0959-8030(93)90030-F Falkinham, 1996, Epidemiology of infection by nontuberculosis mycobacteria, Clin. Microbiol. Rev., 9, 177, 10.1128/CMR.9.2.177 FAO, 2003 Fouz, 2003, Isolation of a new serovar of Vibrio vulnificus pathogenic for eels cultured in freshwater farms, Aquaculture, 217, 667, 10.1016/S0044-8486(02)00200-4 Fouz, 2001, Field testing of a vaccine against eel diseases caused by Vibrio vulnificus, Dis. Aquat. Org., 45, 183, 10.3354/dao045183 Fryer, 1993, The history and current status of Renibacterium salmoninarum, the causative agent of bacterial kidney disease in Pacific salmon, Fish. Res., 17, 15, 10.1016/0165-7836(93)90004-Q Fryer, 1996, Rickettsial infections of fish, Annu. Rev. Fish Dis., 6, 3, 10.1016/S0959-8030(96)90002-2 Fryer, 1990, Isolation of a rickettsiales-like organism from diseased coho salmon (Oncorhynchus kisutch) in Chile, Fish Pathol., 25, 107, 10.3147/jsfp.25.107 Fryer, 1992, Piscirickettsia salmonis gen. nov., sp. nov., the causative agent of an epizootic disease in salmonid fishes, Int. J. Syst. Bacteriol., 42, 120, 10.1099/00207713-42-1-120 Gaggero, 1995, First isolation of Piscirickettsia salmonis from coho salmon, Oncorhynchus kisutch (Walbaum), and rainbow trout, Oncorhynchus mykiss (Walbaum), during the freshwater stage of their life cycle, J. Fish Dis., 18, 227, 10.1111/j.1365-2761.1995.tb00303.x Gómez, 1993, Fish mycobacteriosis: morphological and immunocytochemical aspects, J. Fish Dis., 16, 137, 10.1111/j.1365-2761.1993.tb00857.x Grant, 1996, Rickettsia-like organism in farmed salmon, Vet. Rec., 138, 423 Grayson, 1999, Molecular differentiation of Renibacterium salmoninarum isolates from worldwide locations, Appl. Environ. Microbiol., 65, 961, 10.1128/AEM.65.3.961-968.1999 Grayson, 2000, Molecular diversity of Renibacterium salmoninarum isolates determined by random amplified polymorphic DNA analysis, Appl. Environ. Microbiol., 66, 435, 10.1128/AEM.66.1.435-438.2000 Greger, 1999, Vaccine development for winter ulcer dosese, Vibrio viscosus, in Atlantic salmon, Salmo salar L., J. Fish Dis., 22, 193, 10.1046/j.1365-2761.1999.00163.x Griffiths, 1998, Reduction of Renibacterium salmoninarum culture activity in Atlantic salmon following vaccination with avirulent strains, Fish Shellfish Immunol., 8, 607, 10.1006/fsim.1998.0169 Gudmundsdóttir, 2003, Protection against atypical furunculosis in Atlantic halibut, Hippoglossus hippoglossus (L); comparison of a commercial furunculosis vaccine and an autogenous vaccine, J. Fish Dis., 26, 331, 10.1046/j.1365-2761.2003.00462.x Gustafson, 1992, Detection of Aeromonas salmonicida from fish by using polymerase chain reaction amplification of the virulence surface array protein gene, Appl. Environ. Microbiol., 58, 3816, 10.1128/AEM.58.12.3816-3825.1992 Handlinger, 1997, The pathology of Flexibacter maritimus in aquaculture species of Tasmania, Australia, J. Fish Dis., 20, 159, 10.1046/j.1365-2761.1997.00288.x Hawke, 2003, Molecular and phenotypic characterization of Photobacterium damslae subsp piscicida isolated from hybrid striped bass cultured in Louisiana, USA, J. Aquat. An. Health, 15, 189, 10.1577/H02-043 Heath, 2000, Monitoring Piscirickettsia salmonis by denaturant gel electrophoresis and competitive PCR, Dis. Aquat. Org., 41, 19, 10.3354/dao041019 Hedrick, 1987, Mycobacteriosis in cultured striped bass from California, J. Wildl. Res., 23, 391, 10.7589/0090-3558-23.3.391 Herbst, 2001, Granulomatous skin lesions in Moray eels caused by a novel Mycobacterium species related to Mycobacterium triplex, Infect. Immun., 69, 4639, 10.1128/IAI.69.7.4639-4646.2001 Hiney, 1999, Furunculosis (Aeromonas salmonicida), vol. 3, 341 Hjelmeland, 1988, Isolation and characterization of a surface layer antigen from Vibrio salmonicida, J. Fish Dis., 11, 197, 10.1111/j.1365-2761.1988.tb00540.x Høie, 1997, Evaluation of a polymerase chain reaction-based assay for the detection of Aeromonas salmonicida subsp. salmonicida in Atlantic salmon, Salmo salar, Dis. Aquat. Org., 30, 27, 10.3354/dao030027 Hsu, 1991, Development and evaluation of a monoclonal-antibody-based-enzyme-linked immunosorbent assay for the diagnosis of Renibacterium salmoninarum infection, J. Aquat. Anim. Health, 3, 168, 10.1577/1548-8667(1991)003<0168:DAEOAM>2.3.CO;2 Jones, 1999, Clinical disease in sea farmed Atlantic salmon (Salmo salar) associated with a member of the family Pasteurellaceae, Bull. Eur. Assoc. Fish Pathol., 19, 75 Jones, 1998, Virulence and antigenic characteristics of a cultured Rickettsiales-like organism isolated from farmed Atlantic salmon Salmo salar in eastern Canada, Dis. Aquat. Org., 33, 25, 10.3354/dao033025 Kaattari, 1997, Immunization with bacterial antigens: bacterial kidney disease, 145 Kitao, 1993, Streptococcal infections, 196 Knibb, 1993, Detection and identification of a pathogenic Mycobacterium from European seabass Dicentrarchus labrax using polymerase chain reaction and direct sequencing of 16S rRNA sequences, Mol. Mar. Biol. Biotechnol., 2, 225 Kuo, 1978, Pseudomonas anguilliseptica isolated from red spot disease of pond-cultured eel, Anguilla japonica, Rep. Inst. Fish. Biol., Min. Econ. Aff. Nat. Taiwan Univ., 3, 19 Kusuda, 1991, Enterococcus seriolicida sp. nov., a fish pathogen, Int. J. Syst. Bacteriol., 41, 406, 10.1099/00207713-41-3-406 Kuzyk, 2001, A recombinant subunit vaccine against Piscirickettsia salmonis, O–107 Kvitt, 2002, Photobacterium damselae ssp. piscicida: detection by direct amplification of 16S rRNA gene sequences and genotypic variation as determined by amplified fragment length polymorphism (AFLP), Dis. Aquat. Org., 48, 187 Laidler, 1999, Preliminary investigations into the bacteriology of skin lesions of Atlantic salmon reared in seawater in Scotland, Fish Vet. J., 3, 31 Lämmler, 1998, Differentiation of Streptococcus uberis and Streptococcus parauberis by restriction fragment length polymorphism analysis of the 16S ribosomal RNA gene and further studies on serological properties, Med. Sci. Res., 26, 177 Lannan, 1991, A fluorescent antibody test for detection of the rickettsia causing disease in Chilean salmonids, J. Aquat. Anim. Health, 3, 229, 10.1577/1548-8667(1991)003<0229:AFATFD>2.3.CO;2 Lannan, 1999, Rickettsial and chlamydial infections, vol. 3, 245 Lansdell, 1993, Isolation of several Mycobacterium species from fish, J. Aquat. Anim. Health, 5, 73, 10.1577/1548-8667(1993)005<0073:CIOSMS>2.3.CO;2 Larenas, J.J., Contreras, J., Smith, P., 1999. Estado actual de la Piscirickettsiosis en salmones. AquaTIC1,1–20 (Electronic Journal URL: http://ww.aquatic.unizar.es/N1/art505/ piscrick.htm). Larenas, 2003, Experimental vertical transmission of Piscirickettsia salmonis and in vitro study of attachment and mode of entrance into the fish ovum, Dis. Aquat. Org., 56, 25, 10.3354/dao056025 Larsen, 1994, Vibrio anguillarum serovars associated with vibriosis in fish, J. Fish Dis., 17, 259, 10.1111/j.1365-2761.1994.tb00221.x Lee, 1990, Glycerophospholipid: cholesterol acyltransferase complexed with LPS is a major lethal exotoxin and cytolysin of Aeromonas salmonicida: LPS stabilises and enhances toxicity of the enzyme, J. Bacteriol., 172, 5382, 10.1128/jb.172.9.5382-5393.1990 Lee, 1991, The role of extracellular lethal cytolysin of Aeromonas salmonicida in the pathology of furunculosis, J. Fish Dis., 14, 453, 10.1111/j.1365-2761.1991.tb00597.x Lillehaug, 1990, Cross-protection after immunization of Atlantic salmon Salmo salar L., against different strains of Vibrio salmonicida, J. Fish Dis., 13, 519, 10.1111/j.1365-2761.1990.tb00811.x Lönnström, 1994, Pseudomonas anguilliseptica isolated from Baltic herring Clupea harengus membras with eye lesions, Dis. Aquat. Org., 18, 143, 10.3354/dao018143 López-Romalde, 2003, Phenotypic and genetic characterization of Pseudomonas anguilliseptica strains isolated from fish, J. Aquat. Anim. Health, 15, 39, 10.1577/1548-8667(2003)015<0039:PAGCOP>2.0.CO;2 López-Romalde, 2003, Existence of two O-serotypes in the emerging fish pathogen Pseudomonas anguilliseptica, Vet. Microbiol., 94, 325, 10.1016/S0378-1135(03)00124-X López-Romalde, 2003, Black spot seabream (Pagellus bogaraveo), a new susceptible host for Pseudomonas anguilliseptica, Bull. Eur. Assoc. Fish Pathol., 23, 258 Lunder, 1995, “Winter ulcer” in the Atlantic salmon Salmo salar. Pathological and bacteriological investigations and transmission experiments, Dis. Aquat. Org., 23, 39, 10.3354/dao023039 Lunder, 2000, Phenotypic and genotypic characterization of Vibrio viscosus sp. nov. and Vibrio wodanis sp. nov. isolated from Atlantic salmon (Salmo salar) with “winter ulcer”, Int. J. Syst. Bacteriol., 50, 427, 10.1099/00207713-50-2-427 Magariños, 1992, Phenotypic, antigenic and molecular characterization of Pasteurella piscicida isolated from fish, Appl. Environ. Microbiol., 58, 3316, 10.1128/AEM.58.10.3316-3322.1992 Magariños, 1992, Pathogenic activities of the live cells and extracellular products of the fish pathogen Pasteurella piscicida, J. Gen. Microbiol., 138, 2491, 10.1099/00221287-138-12-2491 Magariños, 1994, Evidence of a dormant but infective state of the fish pathogen Pasteurella piscicida in sea water and sediment, Appl. Environ. Microbiol., 60, 180, 10.1128/AEM.60.1.180-186.1994 Magariños, 1995, Response of Pasteurella piscicida and Flexibacter maritimus to the skin mucus of marine fish, Dis. Aquat. Org., 21, 103, 10.3354/dao021103 Magariños, 1996, Phenotypic and pathobiological characteristics of Pasteurella piscicida, Annu. Rev. Fish Dis., 6, 41, 10.1016/S0959-8030(96)00004-X Magariños, 1997, Applicability of ribotyping for intraspecific classification and epidemiological studies of Pasteurella piscicida, Syst. Appl. Microbiol., 20, 634, 10.1016/S0723-2020(97)80035-5 Magariños, 1999, Protection of gilthead seabream against pasteurellosis at the larval stages, Bull. Eur. Assoc. Fish Pathol., 19, 159 Magariños, 2000, Existence of two geographically linked clonal lineages in the bacterial pathogen Photobacterium damselae subsp. piscicida, Epidemiol. Infect., 125, 213, 10.1017/S0950268899004252 Magariños, 2001, Effect of temperature on the development of pasteurellosis in carrier gilthead seabream (Sparus aurata), Aquaculture, 195, 17, 10.1016/S0044-8486(00)00547-0 Magariños, 2003, Pathobiological characterization of Photobacterium damselae subsp. piscicida strains isolated from cultured sole (Solea senegalensis), Bull. Eur. Assoc. Fish Pathol., 23, 183 Magnússon, 1994, Renibacterium salmoninarum, the causative agent of bacterial kidney disease in salmonid fish, detected by nested reverse transcription-PCR of 16S rRNA sequences, Appl. Environ. Microbiol., 60, 4580, 10.1128/AEM.60.12.4580-4583.1994 Marco-Noales, 2001, Transmission to eels, portals of entry, and putative reservoirs of Vibrio vulnificus serovar E (biotype 2), Appl. Environ. Microbiol., 67, 4717, 10.1128/AEM.67.10.4717-4725.2001 Marschall, 1998, Minimally invasive detection of Piscirickettsia salmonis in cultivated salmonids via PCR, Appl. Environ. Microbiol., 64, 3066, 10.1128/AEM.64.8.3066-3069.1998 Mauel, 1996, Development of polymerase chain reaction assays for detection, identification, and differentiation of Piscirickettsia salmonis, Dis. Aquat. Org., 26, 189, 10.3354/dao026189 Mauel, 1999, Phylogenetic analysis of Piscirickettsia salmonis by 16S, internal transcribed spacer (ITS) and 23S ribosomal DNA sequencing, Dis. Aquat. Org., 35, 115, 10.3354/dao035115 Mauel, 2003, Characterization of a piscirickettsiosis-like disease in Hawaiian tilapia, Dis. Aquat. Org., 53, 249, 10.3354/dao053249 McIntosh, 1996, A simplified PCR-based method for the detection of Renibacterium salmoninarum utilizing preparations of rainbow trout (Oncorhynchus mykiss, walbaum) lymphocytes, Appl. Environ. Microbiol., 62, 2932, 10.1128/AEM.62.11.3929-3932.1996 McVicar, 1979, Fin and skin necrosis of Dover sole Solea solea (L.), J. Fish Dis., 2, 557, 10.1111/j.1365-2761.1979.tb00418.x McVicar, 1982, The prevention and cure of an infectious disease in cultivated juvenile Dover sole Solea solea (L.), Aquaculture, 26, 213, 10.1016/0044-8486(82)90157-0 Midtlyng, 1997, Vaccination against furunculosis, 382 Midtlyng, 1998, Growth of Atlantic salmon Salmo salar after intraperitoneal administration of vaccines containing adjuvants, Dis. Aquat. Org., 32, 91, 10.3354/dao032091 Miriam, 1997, PCR and probe-PCR assays to monitor broodstock Atlantic salmon (Salmo salar, L.) ovarian fluid and kidney tissue for presence of DNA of the fish pathogen Renibacterium salmoninarum, J. Clin. Microbiol., 35, 1322, 10.1128/JCM.35.6.1322-1326.1997 Munn, 1994, The use of recombinant DNA technology in the development of fish vaccines, Fish Shellfish Immunol., 4, 459, 10.1006/fsim.1994.1041 Mutharia, 1992, Antibody specificities of polyclonal rabbit and rainbow trout antisera against Vibrio ordalii and serotype O2 strains of Vibrio anguillarum, Can. J. Microbiol., 39, 492, 10.1139/m93-070 Nakai, 1985, Resistance of Pseudomonas anguilliseptica to bactericidal action of fish serum, Bull. Jpn. Soc. Sci. Fish., 51, 1431, 10.2331/suisan.51.1431 Nakai, 1985, First record of Pseudomonas anguilliseptica infection in cultured ayu, Plecoglossus altivelis, Fish Pathol., 20, 481, 10.3147/jsfp.20.481 Newman, 1993, Bacterial vaccines of fish, Annu. Rev. Fish Dis., 3, 145, 10.1016/0959-8030(93)90033-8 Nguyen, 1999, Selective agars for the isolation of Streptococcus iniae from Japanese flounder, Paralichthys olivaceous, and its cultural environment, J. Appl. Microbiol., 86, 769, 10.1046/j.1365-2672.1999.00724.x Noya, 1995, Interactions between peritoneal exudate cells (PECs) of gilthead seabream (Sparus aurata) and Pasteurella piscicida. A morphological study, Aquaculture, 131, 11, 10.1016/0044-8486(94)00353-P Office International des Epizooties (O.I.E), 2000 Olea, 1993, Detection of Renibacterium salmoninarum in naturally infected Atlantic salmon Salmo salar L., and rainbow trout Oncorhynchus mykiss Walbaum using an enzyme linked immunosorbent assay, Aquaculture, 116, 99, 10.1016/0044-8486(93)90001-F Olsen, 1993, Ribotypes and plasmid contents of Vibrio anguillarum strains in relation to serovars, Appl. Environ. Microbiol., 59, 3863, 10.1128/AEM.59.11.3863-3870.1993 Olsen, 1997, Piscirickettsia salmonis infection in Atlantic salmon Salmo salar in Norway—epidemiological, pathological and microbiological findings, Dis. Aquat. Org., 31, 35, 10.3354/dao031035 Ooyama, 1999, The protective immune response of yellowtail Seriola quinqueradiata to the bacterial fish pathogen Lactococcus garvieae, Dis. Aquat. Org., 37, 121, 10.3354/dao037121 Osorio, 2002, DNA-based diagnostics in sea framing, vol. 7, 253 Osorio, 1999, 16S rRNA sequence analysis of Photobacterium damselae ssp. piscicida and nested PCR method for the rapid detection of the causative agent of fish pasteurellosis, Appl. Environ. Microbiol., 65, 2942, 10.1128/AEM.65.7.2942-2946.1999 Osorio, 2000, Multiplex PCR assay for ureC and 16S rRNA genes clearly discriminates between both subspecies of Photobacterium damselae, Dis. Aquat. Org., 40, 177, 10.3354/dao040177 Ostland, 1999, Flexibacter maritimus associated with a bacterial stomatitis in Atlantic salmon smolts reared in net-pens in British Columbia, J. Aquat. Anim. Health, 11, 35, 10.1577/1548-8667(1999)011<0035:FMAWAB>2.0.CO;2 Palmer, 1997, A piscirickettsiosis-like disease on farmed Atlantic salmon in Ireland—isolation of the agent, Bull. Eur. Assoc. Fish Pathol., 17, 68 Pascho, 1987, Enzyme-linked immunosorbent assay for a soluble antigen of Renibacterium salmoninarum, the causative agent of bacterial kidney disease, Can. J. Fish. Aquat. Sci., 44, 183, 10.1139/f87-024 Pascho, 1987, Comparison of five techniques for the detection of Renibacterium salmoninarum in coho salmon, Trans. Am. Fish. Soc., 11, 882, 10.1577/1548-8659(1987)116<882:COFTFT>2.0.CO;2 Pascho, 1991, Brood stock segregation of spring salmon Oncorhynchus tshawystcha by use of the enzyme linked immunosorbent assay (ELISA) and the fluorescent antibody technique (FAT) affects the prevalence and levels of Renibacterium salmoninarum infection in progeny, Dis. Aquat. Org., 12, 25, 10.3354/dao012025 Pazos, 1993, Increasing occurrence of Flexibacter maritimus in marine aquaculture of Spain, FHS/AFS Newsl., 21, 1 Pazos, 1996, Evaluation of media for the successful culture of Flexibacter maritimus, J. Fish Dis., 19, 193, 10.1111/j.1365-2761.1996.tb00701.x Pedersen, 1993, rRNA gene restriction patterns of Vibrio anguillarum serogroup O1, Dis. Aquat. Org., 16, 121, 10.3354/dao016121 Pedersen, 1999, Extended serotyping scheme for Vibrio anguillarum with the definition of seven provisional O-serogroups, Curr. Microbiol., 38, 183, 10.1007/PL00006784 Perera, 1994, Streptococcus iniae associated with mortality of Tilapia nilotica×T. aurea hybrids, J. Aquat. Anim. Health, 6, 335, 10.1577/1548-8667(1994)006<0335:SIAWMO>2.3.CO;2 Piganelli, 1999, Evaluation of a whole cell, p57-vaccine against the pathogen Renibacterium salmoninarum, Dis. Aquat. Org., 39, 37, 10.3354/dao036037 Ransom, 1984, Comparison of histopathology caused by Vibrio anguillarum and Vibrio ordalii and three species of Pacific salmon, J. Fish Dis., 7, 107, 10.1111/j.1365-2761.1984.tb00913.x Ravelo, 2001, Conventional versus miniaturized systems for the phenotypic characterization of Lactococcus garvieae, Bull. Eur. Assoc. Fish Pathol., 21, 136 Ravelo, 2003, Molecular fingerprinting of Lactococcus garvieae strains by RAPD analysis, J. Clin. Microbiol., 41, 751, 10.1128/JCM.41.2.751-756.2003 Rhodes, 2001, A unique Mycobacterium species isolated from an epizootic of striped bass (Morone saxatilis), Emerg. Infect. Dis., 7, 896, 10.3201/eid0705.010523 Rodger, 1993, Observation of a rickettsia-like organism in Atlantic salmon, Salmo salar L., in Ireland, J. Fish Dis., 16, 361, 10.1111/j.1365-2761.1993.tb00869.x Romalde, 1997, Immunization with bacterial antigens: pasteurellosis, 167 Romalde, 1999, Streptococcosis of marine fish, 1 Romalde, 2002, Molecular approaches for the study and diagnosis of salmonid streptococcosis, 211 Romalde, 1995, Evaluation of Bionor mono-kits for rapid detection of bacterial fish pathogens, Dis. Aquat. Org., 21, 25, 10.3354/dao021025 Romalde, 1999, Pasteurellosis: pathological and epizootiological aspects of the Pasteurella piscicida infection, 1 Romalde, 1999, Assessment of a magnetic bead-EIA based kit for rapid diagnosis of fish pasteurellosis, J. Microbiol. Methods, 38, 147, 10.1016/S0167-7012(99)00088-3 Romalde, 1999, Genetic analysis of turbot pathogenic Streptococcus parauberis strains by ribotyping and random amplified polymorphic DNA, FEMS Microbiol. Lett., 459, 297, 10.1111/j.1574-6968.1999.tb08741.x Romalde, 1999, Prevention of streptococcosis in turbot by intraperitoneal vaccination: a review, J. Appl. Ichthyol., 15, 153 Romalde, 2004, Development and validation of a PCR-based protocol for the detection of Pseudomonas anguilliseptica, Fish Pathol., 39, 33, 10.3147/jsfp.39.33 Romalde, 2005, Vaccination strategies to prevent important emerging diseases for Spanish aquaculture, 85 Salonius, 2003, Further characterization of Arthrobacter davidanieli and use as a live vaccine to immunize against intracellular pathogens of salmonids, 41 Salte, 1994, Winter ulcers of the skin in Atlantic salmon, Salmo salar L., pathogenesis and possible aetiology, J. Fish Dis., 17, 661, 10.1111/j.1365-2761.1994.tb00265.x Sanders, 1980, Renibacterium salmoninarum gen. nov., sp. nov., the causative agent of bacterial kidney disease in salmonid fishes, Int. J. Syst. Bacteriol., 30, 496, 10.1099/00207713-30-2-496 Santos, 1995, Analysis of antigens present in the extracellular products and cell surface of Vibrio anguillarum O1, O2 and O3, Appl. Environ. Microbiol., 61, 2493, 10.1128/AEM.61.7.2493-2498.1995 Santos, 1999, Flexibacter maritimus, causal agent of flexibacteriosis in marine fish, 1 Schieve, 1981, Molecular characterization of Vibrio anguillarum biotype 2, Can. J. Microbiol., 27, 1011, 10.1139/m81-158 Skarmeta, 1995, In vitro killing of Pasteurella piscicida by fish macrophages, Dis. Aquat. Org., 23, 51, 10.3354/dao023051 Skarmeta, 2000, Isolation of a virulent Piscirickettsia salmonis from the brain of naturally infected coho salmon, Bull. Eur. Assoc. Fish Pathol., 20, 261 Skov, 1995, Comparison of pulse-field gel electrophoresis, ribotyping and plasmid profiling for typing of Vibrio anguillarum serovar O1, Appl. Environ. Microbiol., 61, 1540, 10.1128/AEM.61.4.1540-1545.1995 Smith, 1997, Immunization with bacterial antigens: Piscirickettsiosis, 161 Sørensen, 1986, Serotyping of Vibrio anguillarum, Appl. Environ. Microbiol., 51, 593, 10.1128/AEM.51.3.593-597.1986 Sørum, 1990, Plasmid profiling of Vibrio salmonicida for epidemiological studies of cold-water vibriosis in Atlantic salmon (Salmo salar) and cod (Gadus morhua), Appl. Environ. Microbiol., 56, 1033, 10.1128/AEM.56.4.1033-1037.1990 Starliper, 1996, Genetic diversity of North American isolates of Renibacterium salmoninarum, Dis. Aquat. Org., 27, 207, 10.3354/dao027207 Steiropoulos, 2002, Detection of Rickettsia-like organisms (RLOs) in European seabass (Dicentrarchus labrax, L.), Bull. Eur. Assoc. Fish Pathol., 22, 338 Stewart, 1983, An outbreak of “sekiten-byo” among cultured European eels, Anguilla anguilla L., in Scotland, J. Fish Dis., 6, 75, 10.1111/j.1365-2761.1983.tb00052.x Sukui, 2001, Int. J. Syst. Evol. Microbiol., 51, 1639, 10.1099/00207713-51-5-1639 Tajima, 1985, Studies on the taxonomy and serology of causative organisms of fish vibriosis, Fish Pathol., 20, 131, 10.3147/jsfp.20.131 Talaat, 1997, Identification of mycobacteria infecting fish to the species level using polymerase chain reaction and restriction enzyme analysis, Vet. Microbiol., 58, 229, 10.1016/S0378-1135(97)00120-X Talaat, 1999, Pathogenicity of Mycobacterium fortuitum and Mycobacterium smegmatis to gold fish, Carassius auratus, Vet. Microbiol., 66, 151, 10.1016/S0378-1135(99)00002-4 Thornton, 1991, Surface disorganized, attenuated mutants of Aeromonas salmonicida as forunculosis vaccines, Microb. Pathog., 11, 85, 10.1016/0882-4010(91)90002-R Thornton, 1994, The development of live vaccines for forunculosis lacking the A-layer and O-antigen of Aeromonas salmonicida, J. Fish Dis., 17, 195, 10.1111/j.1365-2761.1994.tb00215.x Thune, 2003, Construction of a safe, stable, efficacious vaccine against Photobacterium damselae sp. piscicida, Dis. Aquat. Org., 57, 51, 10.3354/dao057051 Thyssen, 2000, Application of AFLP for taxonomic and epidemiological studies of Photobacterium damselae ssp. piscicida, Int. J. Syst. Evol. Microbiol., 50, 1013, 10.1099/00207713-50-3-1013 Tiainen, 1995, Ribotyping and plasmid profiling of Vibrio anguillarum serovar O2 and Vibrio ordalii, J. Appl. Bacteriol., 79, 384, 10.1111/j.1365-2672.1995.tb03152.x Tison, 1982, Vibrio vulnificus biotype 2: new biogroup pathogenic for eels, Appl. Environ. Microbiol., 44, 640, 10.1128/AEM.44.3.640-646.1982 Toranzo, 1990, A review of the taxonomy and seroepizootiology of Vibrio anguillarum, with special reference to aquaculture in the northwest of Spain, Dis. Aquat. Org., 9, 73, 10.3354/dao009073 Toranzo, 1992, First report of furunculosis in turbot reared in floating cages in northwest of Spain, Bull. Eur. Assoc. Fish Pathol., 12, 147 Toranzo, 1993, Virulence factors of bacteria pathogenic for cold water fish, Annu. Rev. Fish Dis., 3, 5, 10.1016/0959-8030(93)90027-9 Toranzo, 1983, Characterization of plasmids in bacterial fish pathogens, Infect. Immun., 39, 184, 10.1128/IAI.39.1.184-192.1983 Toranzo, 1987, Specificity of slide agglutination test for detecting bacterial fish pathogens, Aquaculture, 61, 81, 10.1016/0044-8486(87)90361-9 Toranzo, 1991, Pasteurellosis in cultured gilthead seabream (Sparus aurata): first report in Spain, Aquaculture, 99, 1, 10.1016/0044-8486(91)90284-E Toranzo, 1991, Biochemical and serological characteristics, drug resistance, and plasmid profiles of Spanish isolates of Aeromonas salmonicida, Fish Pathol., 26, 55, 10.3147/jsfp.26.55 Toranzo, 1994, Streptococcosis in cultured turbot caused by an Enterococcus-like bacterium, Bull. Eur. Assoc. Fish Pathol., 14, 19 Toranzo, 1995, Antigenic characterization of Enterococcus strains pathogenic for turbot and their relationship with other gram positive bacteria, Dis. Aquat. Org., 21, 187, 10.3354/dao021187 Toranzo, 1995, Efficacy of intraperitoneal and immersion vaccination against Enterococcus sp. infection in turbot, Aquaculture, 134, 17, 10.1016/0044-8486(95)00038-4 Toranzo, 1997, Immunization with bacterial antigens: Vibrio infections, 93 Toyama, 1996, Identification of Flexibacter maritimus, Flavobacterium branchiophilum and Cytophaga columnaris by PCR targeted 16S ribosomal DNA, Fish Pathol., 31, 25, 10.3147/jsfp.31.25 Vaughan, 1993, An aromatic-dependent mutant of the fish pathogen Aeromonas salmonicida, is attenuated and its effective as a live vaccine against the salmonid disease, furunculosis, Infect. Immun., 61, 2172, 10.1128/IAI.61.5.2172-2181.1993 Vela, 2000, Phenotypic and genetic characterization of Lactococcus garvieae isolated in Spain from lactococcosis outbreaks in comparison with isolates of other countries and sources, J. Clin. Microbiol., 38, 3791, 10.1128/JCM.38.10.3791-3795.2000 Wakabayashi, 1972, Characteristics of a Pseudomonas sp. from an epizootic of pond-cultured eels (Anguilla japonica), Bull. Jpn. Soc. Sci. Fish., 38, 577, 10.2331/suisan.38.577 Wakabayashi, 1986, Flexibacter maritimus sp. nov., a pathogen of marine fishes, Int. J. Syst. Bacteriol., 36, 396, 10.1099/00207713-36-3-396 Weinstein, 1997, Invasive infections due to a fish pathogen, Streptococcus iniae, N. Engl. J. Med., 337, 589, 10.1056/NEJM199708283370902 Wiens, 1999, Bacterial kidney disease (Renibacterium salmoninarum), vol. 3, 269 Wiklund, 1990, Pseudomonas anguilliseptica as a pathogen of salmonid fish in Finland, Dis. Aquat. Org., 8, 13, 10.3354/dao008013 Wood, 1996, Enhanced immunogenicity of Renibacterium salmoninarum in chinook salmon after removal of the bacterial cell surface-associated 57 kDa protein, Dis. Aquat. Org., 25, 71, 10.3354/dao025071 Yoshida, 1996, Phenotypic variation associated with an antiphagocytic factor in the bacterial fish pathogen Enterococcus seriolicida, Dis. Aquat. Org., 25, 81, 10.3354/dao025081 Zlotkin, 1998, Possible transmission of Streptococcus iniae from wild fish to cultured marine fish, Appl. Environ. Microbiol., 64, 4065, 10.1128/AEM.64.10.4065-4067.1998 Zlotkin, 1998, Identification of Lactococcus garvieae by PCR, J. Clin. Microbiol., 36, 983, 10.1128/JCM.36.4.983-985.1998 Zorrilla, 1999, Isolation and characterization of the causative agent of pasteurellosis, Photobacterium damsela ssp. piscicida, from sole Solea senegalensis (Kaup), J. Fish Dis., 22, 167, 10.1046/j.1365-2761.1999.00157.x