Constipation and risk of Parkinson’s disease: A Danish population-based cohort study

Ross, 2012, Pre-motor features of Parkinson’s disease: the Honolulu-Asia aging study experience, Park. Relat. Disord., 18, S199, 10.1016/S1353-8020(11)70062-1 Chen, 2015, Meta-analyses on prevalence of selected Parkinson’s nonmotor symptoms before and after diagnosis, Transl. Neurodegener., 4, 1, 10.1186/2047-9158-4-1 Noyce, 2012, Meta-analysis of early nonmotor features and risk factors for Parkinson disease, Ann. Neurol., 72, 893, 10.1002/ana.23687 Abbott, 2001, Frequency of bowel movements and the future risk of Parkinson’s disease, Neurology, 57, 456, 10.1212/WNL.57.3.456 Adams-Carr, 2015, Constipation preceding Parkinson’s disease: a systematic review and meta-analysis, J. Neurol. Neurosurg. Psychiatry, 10.1136/jnnp-2015-312379.98 McCrea, 2009, A review of the literature on gender and age differences in the prevalence and characteristics of constipation in North America, J. Pain Symptom Manage, 37, 737, 10.1016/j.jpainsymman.2008.04.016 Savica, 2009, Medical records documentation of constipation preceding Parkinson disease: a case-control study, Neurology, 73, 1752, 10.1212/WNL.0b013e3181c34af5 Gao, 2011, A prospective study of bowel movement frequency and risk of Parkinson’s disease, Am. J. Epidemiol., 174, 546, 10.1093/aje/kwr119 Savica, 2010, When does Parkinson disease start?, Arch. Neurol., 67, 798, 10.1001/archneurol.2010.135 Schmidt, 2014, The danish civil registration system as a tool in epidemiology, Eur. J. Epidemiol., 29, 541, 10.1007/s10654-014-9930-3 Lynge, 2011, The danish national patient register, Scand. J. Public Health, 39, 30, 10.1177/1403494811401482 World Health Organization, 1993 Wirdefeldt, 2011, Epidemiology and etiology of Parkinson’s disease: a review of the evidence, Eur. J. Epidemiol., 26, S1, 10.1007/s10654-011-9581-6 Ritz, 2014, Parkinson disease and smoking revisited: ease of quitting is an early sign of the disease, Neurology, 83, 1396, 10.1212/WNL.0000000000000879 Hajek, 2003, Stopping smoking can cause constipation, Addiction, 98, 1563, 10.1046/j.1360-0443.2003.00497.x Bytzer, 2001, Prevalence of gastrointestinal symptoms associated with diabetes mellitus: a population-based survey of 15,000 adults, Arch. Intern Med., 161, 1989, 10.1001/archinte.161.16.1989 Ehrenstein, 2010, Existing data sources for clinical epidemiology: Aarhus University prescription Database, Clin. Epidemiol., 2, 273, 10.2147/CLEP.S13458 Rief, 2009, Differences in adverse effect reporting in placebo groups in SSRI and tricyclic antidepressant trials: a systematic review and meta-analysis, Drug Saf., 32, 1041, 10.2165/11316580-000000000-00000 Miller, 2010, Gender differences in Parkinson’s disease: clinical characteristics and cognition, Mov. Disord., 25, 2695, 10.1002/mds.23388 Oh, 2013, Estrogen rather than progesterone cause constipation in both female and male mice, Korean J. Physiol. Pharmacol., 17, 423, 10.4196/kjpp.2013.17.5.423 Liu, 2007, Oestrogen and nigrostriatal dopaminergic neurodegeneration: animal models and clinical reports of Parkinson’s disease, Clin. Exp. Pharmacol. Physiol., 34, 555, 10.1111/j.1440-1681.2007.04616.x Greene, 2014, Reproductive factors and Parkinson’s disease risk in Danish women, Eur. J. Neurol., 21, 1168, 10.1111/ene.12450 Wermuth, 2012, Validation of hospital register-based diagnosis of Parkinson’s disease, Dan. Med. J., 59, A4391 Klingelhoefer, 2015, Pathogenesis of Parkinson disease-the gut-brain axis and environmental factors, Nat. Rev. Neurol., 11, 625, 10.1038/nrneurol.2015.197 Cersosimo, 2008, Neural control of the gastrointestinal tract: implications for Parkinson disease, Mov. Disord., 23, 1065, 10.1002/mds.22051 Hawkes, 2007, Parkinson’s disease: a dual-hit hypothesis, Neuropathol. Appl. Neurobiol., 33, 599, 10.1111/j.1365-2990.2007.00874.x Braak, 2003, Idiopathic Parkinson’s disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen, J. Neural Transm., 110, 517, 10.1007/s00702-002-0808-2 Holmqvist, 2014, Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats, Acta Neuropathol., 128, 805, 10.1007/s00401-014-1343-6 Svensson, 2015, Vagotomy and subsequent risk of Parkinson’s disease, Ann. Neurol., 78, 522, 10.1002/ana.24448