Theory formation in postulating enzyme kinetic mechanisms: Reasoning with constraints

Computers and Biomedical Research - Tập 21 - Trang 381-403 - 1988
Von-Wun Soo1, Casimir A. Kulikowski1, David Garfinkel2, Lillian Garfinkel2
1Department of Computer Science, Rutgers University, New Brunswick, New Jersey 08903 USA
2Department of Computer Science, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6389 USA

Tài liệu tham khảo

Langley, 1983, Mechanisms for qualitative and quantitative discovery Zytkow, 1986, A theory of historical discovery: The construction of componential models, Mach. Learn., 1, 107, 10.1007/BF00116252 Stefik, 1980, Planning with Constraints Friedland, 1985, Discovering the secrets of DNA, Commun. ACM, 28, 1164, 10.1145/4547.4550 Kohn, 1979, A convenient computer program for fitting enzymatic rate laws to steady-state data, Comput. Biomed. Res., 12, 461, 10.1016/0010-4809(79)90032-6 Soo, 1987, Automation by artificial intelligence techniques of the expert reasoning in deriving kinetic models for enzymes especially hexokinase, 46, 274ABS Garfinkel, 1987, Kinetic properties of hexokinase as assembled with a microcomputer data base, Biochem. J., 244, 351, 10.1042/bj2440351 Garfinkel, 1986, A microcomputer-based enzyme kinetics data base, Vol. 1, 128 Cleland, 1963, The kinetics of enzyme-catalyzed reactions with two or more substrates. III. Prediction of initial velocity and inhibitions by inspection, Biochim. Biophys. Acta, 67, 188, 10.1016/0926-6569(63)90227-X Roman, 1978, BIOSSIM—A structured machine-independent biological simulation language, Comput. Biomed. Res., 11, 3, 10.1016/0010-4809(78)90042-3 Cornish-Bowden, 1977, An automatic method for deriving steady-state rate equations, Biochem. J., 165, 55, 10.1042/bj1650055 Lam, 1979, A systematic computerized method for building enzyme kinetic models, Comput. Biol. Med., 9, 305, 10.1016/0010-4825(79)90037-4 Garfinkel, 1977, Systems analysis in enzyme kinetics, CRC Crit. Rev. Bioeng., 2, 329 1981 Markus, 1980, Analysis of progress curves: Rate of pyruvate kinase from Escherichia coli, Biochem. J., 189, 421, 10.1042/bj1890421 Mannervik, 1975, Nonlinear regression methods in design of experiments and mathematical modelling: Applications to the analysis of the steady-state glutathione reaction, Biosystems, 7, 101, 10.1016/0303-2647(75)90048-9 Cornish-Bowden, 1978, Evaluation of rate constants for enzyme-catalyzed reactions by the jackknife technique: Application to liver alcohol dehydrogenase, Biochem. J., 175, 969, 10.1042/bj1750969 Ricard, 1985, Kinetic cooperativity of monomeric mnemonical enzymes: The significance of the kinetic Hill Coefficient, Eur. J. Biochem., 152, 557, 10.1111/j.1432-1033.1985.tb09231.x Emerk, 1975, Rabbit muscle phosphofructokinase: The effect of the state of the enzyme and assay procedures on the kinetic properties, Arch. Biochem. Biophys., 218, 210, 10.1016/0003-9861(75)90243-X Cleland, 1963, The kinetics of enzyme catalyzed reactions with two or more substrates or products. I. Nomenclature and rate equations, Biochim. Biophys. Acta, 67, 104, 10.1016/0926-6569(63)90211-6 Cleland, 1963, The kinetics of enzyme catalyzed reactions with two or more substrates or products. II. Inhibition: Nomenclature and theory, Biochim. Biophys. Acta, 67, 173, 10.1016/0926-6569(63)90226-8 Wong, 1974 Segel, 1975 Toews, 1966, Kinetic studies with skeletal-muscle hexokinase, Biochem. J., 100, 739, 10.1042/bj1000739 Kosow, 1968, Ascites tumor mitochondrial hexokinase II, J. Biol. Chem., 243, 3623, 10.1016/S0021-9258(19)34185-7 Hayes-Roth, 1986, PROTEAN: Deriving protein structure from constraints, 904 Sridharan, 1978, Knowledge-directed inference in BELIEVER, 361 Srinivasan, 1976, The architecture of coherent information system: A general problem solving system, IEEE Trans. Comput., C25, 390, 10.1109/TC.1976.1674621 Mitchell, 1986, Explanation-based generalization: A unifying view, Mach. Learn., 1, 47, 10.1007/BF00116250 Kuipers, 1984, Commonsense reasoning about causality: Deriving behavior from structure, Artif. Intelligence, 24, 169, 10.1016/0004-3702(84)90039-0 Soo, 1985, An expert systems approach to steady state modeling and simulation in enzyme kinetocs, Vol. 3, 141