In vitro reactivity of allospecific cytotoxic T lymphocytes does not explain the taboo phenomenon

Opelz, 1977, Studies on the strength of HLA antigens in related donor kidney transplantation, Transplantation, 24, 106, 10.1097/00007890-197708000-00003 Opelz, 1988, Importance of HLA antigen splits for kidney transplant matching, Lancet, 2, 61, 10.1016/S0140-6736(88)90001-3 Thorogood, 1990, The effect of HLA matching on kidney graft survival in separate post-transplantation intervals, Transplantation, 50, 146, 10.1097/00007890-199007000-00027 Gjertson, 1991, National allocation of cadaveric kidneys by HLA matching. Projected effect on outcome and costs, N Engl J Med, 324, 1032, 10.1056/NEJM199104113241505 van Rood, 1993, Permissible mismatches, acceptable mismatches, and tolerance: new trends in decision making, 285 Benacerraf, 1981, Role of MHC gene products in immune regulation, Science, 212, 1229, 10.1126/science.6165083 Hsu, 1981, Genetic control of major histocompatibility complex-linked immune responses to synthetic polypeptides in man, Proc Natl Acad Sci USA, 78, 440, 10.1073/pnas.78.1.440 Moller, 1983, HLA and disease susceptibility, Immunol Rev, 70, 113 Vries, 1985, HLA class II immune response genes and products in leprosy, Prog Allergy, 36, 95 Busson, 1979, Is the strength of single HLA antigen mismatch variable in kidney transplant survival?, Transplantation, 28, 313, 10.1097/00007890-197910000-00009 Hendriks, 1983, HLA-DRw6 and renal allograft rejection, BMJ, 286, 85, 10.1136/bmj.286.6359.85 Hendriks, 1983, Excellent outcome after transplantation of renal allografts from HLA-DRw6-positive donors even in HLA-DR mismatches, Lancet, ii, 187, 10.1016/S0140-6736(83)90172-1 Dyer, 1985, HLA-DR3 is a marker of graft failure in cadaveric renal transplantation, Transplant Proc, 17, 2248 Dobbe, 1990, An unexpected effect of matching for HLA-A9 in renal transplantation, Transplantation, 50, 446, 10.1097/00007890-199009000-00017 Goulmy, 1992, The influence of HLA-A2 subtype mismatch on renal allograft survival, Transplantation, 53, 1381, 10.1097/00007890-199206000-00046 Alamartine, 1992, Influence of HLA antigens of renal transplant recipients on graft survival, Transplant Proc, 24, 2461 Soulillou, 1983, Poor kidney graft survival in recipients with HLA-DRw6, N Engl J Med, 308, 969, 10.1056/NEJM198304213081620 Forsberg, 1992, Influence of recipient's HLA type on the outcome of renal transplantation, Transplant Proc, 24, 2463 Vereerstraeten, 1987, Donor-recipient (DR) antigen combinations in cadaver renal graft survival: a new approach to recipient selection, Transplant Proc, 19, 3647 Roelen, 1994, Cytotoxic T lymphocytes against HLA-B antigens are less naive than cytotoxic T lymphocytes against HLA-A antigens, Transplantation, 57, 446, 10.1097/00007890-199402150-00023 Zantvoort, 1996, The relevance of HLA-A matching in first unrelated renal allografts, Transplantation, 61, 841, 10.1097/00007890-199603150-00030 Maruya, 1993, HLA matching: identification of permissible HLA mismatches, 511 Doxiadis, 1996, Association between specific HLA combinations and probability of kidney allograft loss: the taboo concept, Lancet, 348, 850, 10.1016/S0140-6736(96)02296-9 Doxiadis, 1996, Taboo HLA mismatches in cadaveric renal transplantation: definition, analysis and possible implications, Transplant Proc, 28, 224 Alfani, 1997, Analysis of 160 consecutive living unrelated kidney transplants: 1983–1997, Transplant Proc, 29, 3399, 10.1016/S0041-1345(97)00954-8 Bradley, 1985, Evidence that rat renal allograft are rejected by cytotoxic T cells and not by nonspecific effectors, Transplantation, 39, 169, 10.1097/00007890-198502000-00012 Mast, 1997, Modulation of the T cell compartment by blood transfusion. Effect on cytotoxic and helper T lymphocyte precursor frequencies and T cell receptor V beta usage, Transplantation, 63, 1145 Bouma, 1992, Determination of cytotoxic T-lymphocyte precursor frequencies using europium labeling as a nonradioactive alternative to labeling with chromium-51, Hum Immunol, 35, 85, 10.1016/0198-8859(92)90015-F Detrisac, 1984, Tissue culture of human kidney epithelial cells of proximal tubule origin, Kidney Int, 25, 383, 10.1038/ki.1984.28 Deckers, 1997, Tissue-specific characteristics of cytotoxic graft infiltrating T cells during real allograft rejection, Transplantation, 64, 178, 10.1097/00007890-199707150-00034 Strijbosch, 1987, Limiting dilution assays: experimental design and statistical analysis, J Immunol Methods, 97, 133, 10.1016/0022-1759(87)90115-3 Rammensee, 1995, MHC ligands and peptide motifs: first listing, Immunogenetics, 41, 178, 10.1007/BF00172063 van der Burg, 1995, An HLA class I peptide-binding assay based on competition for binding to class I molecules on intact human B-cells: Identification of conserved HIV-1 polymerase peptides binding to HLA-A*0301, Hum Immunol, 44, 189, 10.1016/0198-8859(95)00105-0 Burrows, 1992, The specificity of recognition of a cytotoxic T lymphocyte epitope, Eur J Immunol, 22, 191, 10.1002/eji.1830220128 Steinle, 1995, In vivo expansion of HLA-B35 alloreactive T cells sharing homologous T cell receptors: Evidence for maintenance of an oligoclonally dominated allospecificity by persistent stimulation with an autologous MHC/peptide complex, J Exp Med, 181, 503, 10.1084/jem.181.2.503 Silins, 1998, A functional link for major TCR expansions in healthy adults caused by persistent Epstein-Barr virus infection, J Clin Invest, 102, 1551, 10.1172/JCI4225 Lombardi, 1990, Are primary alloresponses truly primary?, Int Immunol, 2, 9, 10.1093/intimm/2.1.9 Loftus, 1997, Differential contact of disparate class I/peptide complexes as the basis for epitope cross-recognition by a single T cell receptor, J Immunol, 158, 3651, 10.4049/jimmunol.158.8.3651 Burrows, 1999, The influence of antiviral T-cell responses on the alloreactive repertoire, Immunol Today, 20, 203, 10.1016/S0167-5699(98)01429-7 Udalova, 1993, Highly informative typing of the human TNF locus using six adjacent polymorphic markers, Genomics, 16, 180, 10.1006/geno.1993.1156 Verjans, 1991, Restriction fragment length polymorphism of the tumor necrosis factor region in patients with ankylosing spondylitis, Arthr Rheum, 34, 486, 10.1002/art.1780340414 Wichelow, 1996, The effect of TNF*B gene polymorphism on the TNF-alpha and -beta secretion levels in patients with insulin-dependent diabetis mellitus and healthy controls, Eur J Immunogenet, 23, 425, 10.1111/j.1744-313X.1996.tb00133.x Weissensteiner, 1997, TNFB polymorphisms characterize three lineages of TNF region microsatellite haplotypes, Immunogenetics, 47, 6, 10.1007/s002510050320 Wilson, 1993, An allelic polymorphism within the human tumor necrosis factor alpha promotor region is strongly associated with HLA-A1, -B8, and -DR3 alleles, J Exp Med, 177, 557, 10.1084/jem.177.2.557 Hanifi Moghaddam, 1998, D6s TNFa microsatellite locus correlates with CTLp frequency in unrelated bone marrow donor-recipient pairs, Hum Immunol, 59, 295, 10.1016/S0198-8859(98)00022-6