Cytological diagnosis of parasites presenting as superficial nodular swelling: report of 35 cases
Tóm tắt
Parasitic infestation often present with superficial nodular swelling. Fine needle aspiration cytology plays an important role in prompt diagnosis of the disease. To study the role of FNAC in the diagnosis of parasites presenting as skin or subcutaneous nodules. Total 361 cases of superficial swellings at various sites were subjected to fine needle aspiration cytology. Out of the 361 cases, 35 cases were diagnosed as suggestive of parasitic infestation. These 35 cases form the study group. In 14 cases out of 35 cases, a definitive diagnosis of parasitic infestation was made as parasite or fragments of parasite were seen in the aspirate. In 21 cases, neither parasite nor fragments could be identified on the aspirates and a diagnosis of parasitic inflammation was suggested on the basis of other cytomorphological findings. In 17 of these cases, a biopsy correlation was available, which revealed definitive parasite in 8 cases and the remaining 9 were reported as suggestive of parasitic cyst. The cytological diagnosis was confirmatory in cases where the parasite fragment were identified in the smears. However, in other cases, clear aspirate, presence of eosinophils, macrophages and typical granular dirty background are the features which should prompt the cytologist to the possibility of parasitic infestation.
Tài liệu tham khảo
Abu-Eshy SA (1998) Some rare presentations of hydatid cyst (Echinococcosis granulosus). J R Col Surg Edinb 43:347–352
Adhikari RC, Aryal G, Jha A, Pant AD, Sayami G (2007) Diagnosis of subcutaneous cysticercosis in fine needle aspirates: a study of 10 cases. Nepal Med Col J 9:234–238
Arora VK, Gupta K, Singh N, Bhatia A (1994) Cytomorphologic panorama of cysticercosis on fine needle aspiration: a review of 298 cases. Acta Cytol 38:377–380
Arora VK, Singh N, Bhatia A (1996) Cytomorphologic profile of lymphatic filariasis. Acta Cytol 40:948–952
Ash LR, Orihel TC (1990) Larval cestode parasite in humans. Atlas of human parasitology, 3rd edn. American Society of Clinical Pathologists, Chicago, IL, pp 236–237
Bapat KC, Pandit AA (1992) Filarial infection of the breast: report of a case with diagnosis by fine needle aspiration cytology. Acta Cytol 36:505–506
Chowdhary M, Langer S, Aggarwal M, Agarwal C (2008) Microfilaria in thyroid gland nodule. Indian J Pathol Microbiol 51:94–96
Hofman P, Huerre M (2002) Cytopathologist’s role in detecting and identifying pathogens. Ann Pathol 22(4):289–304
Jain S, Sodhani P, Gupta S, Sakhuja P, Kumar N (2001a) Cytomorphology of filariasis revisited: expansion of the morphologic spectrum and coexistence with other lesions. Acta Cytol 45:186–191
Jain S, Sodhani P, Gupta S, Sakhuja P, Kumar N (2001b) Cytomorphology of filariasis revisited: expansion of the morphologic spectrum and coexistence with other lesions. Acta Cytol 45:186–191
Jayaram G (1989) Microfilariae in fine needle aspirates from epididymal lesions. Acta Cytol 31:59–62
Kapila K, Verma K (1996) Diagnosis of parasites in fine needle breast aspirates. Acta Cytol 40:653–656
Kiresi DA, Karabacakoglu A, Odev K, Karakose S (2003) Uncommon locations of hydatid cysts. Acta Radiol 44:622
Kumar ND, Misra K (1991) Fine-needle aspiration cytology of subcutaneous cysticercosis. Diagn Cytopathol 7:223–224
Kung ITM, Lee D, Yu HC (1989) Soft tissue cysticercosis: diagnosis by fine needle aspiration. Am J Clin Pathol 92:834–835
Leiman G (1999) Liver and spleen. In: Orell SR, Sterrett GF, Walters MN-I, Whitakar D (eds) Manual and atlas of fine needle aspiration cytology, 3rd edn. Churchill Livingstone, London, p 273
Martin HE, Ellis EB (1930) Biopsy by needle puncture and aspiration. Ann Surg 62:169–181
Noroes J, Addiss D, Amara F, Coutinho A, Mederios Z, Dreyer G (1996) Occurrence of living adult Wuchereria bancrofti in scrotal area of men with microfilaremia. Trans R Soc Trop Med Hyg 90:55–56
Pandit AA, Shah RK, Shenoy SG (1997) Adult filarial worm in a fine needle aspirates of a soft tissue swelling. Acta Cytol 41:944–946
Rajwanshi A, Radhika S, Das A, Jayaram N, Banerjee CK (1991) Fine-needle aspiration cytology in the diagnosis of cysticercosis presenting as palpable nodules. Diagn Cytopathol 7:517–519
Rukmangadha N, Shanthi V, Kiran CM, Nalini PK, Sarella JB (2006) Breast filariasis diagnosed by fine needle aspiration cytology: a case report. Indian J Pathol Microbiol 49:243–244
Sharma P, Kumar N, Jain P, Gur R, Jain S (2005) Chronic wuchereriasis presenting as a vaginoperineal fistula: report of a case with aspiration cytologic diagnosis. Acta Cytol 49:335–338
Singh N, Arora VK, Bhatia A (2006) Are all subcutaneous parasitic cysts cysticercosis? Acta Cytol 50(1):114–115
Varghese R, Raghuveer CV, Pai MR, Bansal R (1996) Microfilariae in cytologic smear: a report of six cases. Acta Cytol 40:299–301
Verma K, Kapila K (1989) Fine needle aspiration diagnosis of cysticerci in soft tissue swellings. Acta Cytol 33:663–666
Yenkeshwar PN, Dinkar T, Sudhakar K, Bobhate K (2006) Microfilariae in fine needle aspirates: a report of 22 cases. Indian J Pathol Microbiol 49:365–369