The allen latham award lecture: specific immunotherapy for autoimmune disease

Lockwood, 1975, Recovery from Goodpasture's syndrome after immunosuppressive treatment and plasmapheresis, Br Med J, 2, 252, 10.1136/bmj.2.5965.252 Savage, 1993, Sytemic vasculitides, Vol. II, 1205 Gross, 1993, ANCA and associated diseases: immunodiagnostic and pathogenetic aspects, Clin Exp Immunol, 91, 1, 10.1111/j.1365-2249.1993.tb03345.x Jayne, 1989, Severe pulmonary haemorrhage and systemic vasculitis in association with circulating antineutrophil antibodies of IgM class only, Clin Nephrol, 32, 101 Esnault, 1992, Association of IgM with IgG ANCA in patients presenting with pulmonary haemorrhage, Kidney Int, 41, 1304, 10.1038/ki.1992.194 Thomas, 1992, Pulmonary-renal syndrome in association with anti-GBM and IgM ANCA antibodies, Lancet, 339, 1304, 10.1016/0140-6736(92)91640-T Ronda, 1994, Antineutrophil cytoplasm antibodies (ANCA) of IgA isotype in adult Henoch-Schonlein purpura, Clin Exp Immunol, 95, 49, 10.1111/j.1365-2249.1994.tb06013.x Jayne, 1991, The IgG subclass of autoantibodies to neutrophil cytoplasmic antigens in systemic vasculitis, Clin Exp Immunol, 84, 476 Esnault, 1991, IgG subclass distribution and relative functional affinity of anti-myeloperoxidase antibodies in systemic vasculitis at presentation and follow-up, Immunology, 74, 714 Esnault, 1993, Association of ANCA isotype and affinity with disease expression, J Autoimmun, 6, 197, 10.1006/jaut.1993.1017 Rossi, 1991, Anti-idiotypes against antineutrophil cytoplasmic antigen autoantibodies in normal human polyspecific IgG for therapeutic use and in the remission sera of patients with systemic vasculitis, Clin Exp Immunol, 83, 298, 10.1111/j.1365-2249.1991.tb05631.x Lockwood, 1993, Specificity and pathogenicity of antineutrophil cytoplasm antibodies, Exp Nephrol, 1, 13 Lockwood, 1993, Humanised monoclonal antibody therapy for intractable systemic vasculits, Lancet, 341, 1620, 10.1016/0140-6736(93)90759-A Falk, 1988, Antineutrophil cytoplasmic antibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotising and crescentic glomerulonephritis, New Engl J Med, 318, 1651, 10.1056/NEJM198806233182504 Cohen Tervaert JW, Huitema MG, Dolman KM, Goldschmeding R, The TH, Kallenberg CGM: The clinical significance of autoantibodies to human leucocyte elastase. Br J Rheumatol. In press. Schmitt, 1993, Autoantibodies against lysozyme: A new target antigen for antineutrophil cytoplasm antibodies (ACNA), Adv Exp Med Biol., 336, 267, 10.1007/978-1-4757-9182-2_40 Halbacks-Mecarelli, 1992, Antineutrophil cytoplasmic antibodies (ANCA) directed against cathepsin G in ulcerative colitis, Crohn's disease and primary sclerosing cholangitis, Clin Exp Immunol, 90, 79, 10.1111/j.1365-2249.1992.tb05835.x Lesavre, 1990, Antineutrophil cytoplasmic antibodies (ANCA) with antilactoferrin activity in vasculitis, Kidney Int, 37, 442 Peter, 1993, ANCA in diseases other than systemic vasculitis, Clin Exp Immunol, 93, 12 Klein, 1991, Significance and specificity of antibodies to neutrophils detected by Western blotting for serological diagnosis of primary sclerosing cholangitis, Hepatology, 14, 1147, 10.1002/hep.1840140632 Mulder, 1993, Prevalence and characterisation of neutrophil cytoplasmic antibodies in autoimmune liver diseases, Hepatology, 17, 411, 10.1002/hep.1840170310 Saxon, 1990, A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease, J Allergy Clin Immunol, 86, 202, 10.1016/S0091-6749(05)80067-3 Rump, 1990, A new type of perinuclear antineutrophil cytoplasmic antibody (pANCA) in active ulcerative colitis but not in Crohn's disease, Immunology, 181, 406 Duerr, 1991, Antineutrophil cytoplasmic antibodies ulcerative colitis: a link between primary sclerosing cholangitis and ulcerative colitis, Gastroenterology, 100, 1385, 10.1016/0016-5085(91)70028-V Falk, 1990, Antineutrophil cytoplasm antibodies induce neutrophils to degranulate and produce toxic oxygen radicals in vitro, 87, 4115 Maget, 1993, Antibodies to proteinase 3 increase adhesion of neutrophils to human endothelial cells, Clin Exp Immunol, 94, 440 Ewert, 1992, Antimyeloperoxidase antibodies stimulate neutrophils to damage human endothelial cells, Kidney Int, 41, 375, 10.1038/ki.1992.52 Maget, 1993, Human endothelial cells express proteinase 3, the target antigen of anticytoplasmic antibodies in Wegener's granulomatosis, Blood, 82, 1221, 10.1182/blood.V82.4.1221.1221 Dolman, 1993, Relevance of classic antineutrophil cytoplasmic autoantibody (C-ANCA)-mediated inhibition of proteinase 3-α1-antitrypsin complexation to disease activity in Wegener's granulomatosis, Clin Exp Immunol, 93, 405, 10.1111/j.1365-2249.1993.tb08192.x Jayne DRW, Gaskin G, Pusey CD, Lockwood CM: ANCA and the prediction of relapse in systemic vasculitis. Submitted. Hind, 1984, Objective monitoring of activity of Wegener's granulomatosis by measurement of C-reactive protein concentration, Clin Nephrol, 21, 314 Schmitt, 1992, Elevated serum levels of soluble interleukin 2 receptor in patients with Wegener's granulomatosis, Arthritis Rheum, 35, 1088, 10.1002/art.1780350914 Grau, 1989, Serum cytokine changes in systemic vasculitis, Immunology, 68, 196 Pall, 1993, Circulating adhesion molecules in systemic vasculitis, Clin Exp Immunol, 93, 32 Hoffman, 1992, Wegener's granulomatosis: An analysis of 158 patients, Ann Intern Med, 116, 488, 10.7326/0003-4819-116-6-488 Reuter H, Wraight P, Zhao MH, Qasim FJ, Lockwood CM: Clinical significance of radiological imaging and determining autoantibody specificity in systemic vasculitis. Submitted. Savage, 1985, Microscopic polyarteritis: presentation, pathology and prognosis, Q J Med, 220, 467 Moguilevsky, 1991, Structural and biological properties of human recombinant myeloperoxidase produced by Chinese hamster ovary cell lines, Eur J Biochem, 197, 605, 10.1111/j.1432-1033.1991.tb15950.x Short, 1991, Recombinant myeloperoxidase as an antigen in ANCA positive vasculitis, Clin Exp Immunol, 93, 21 Finnern, 1993, Anti-neutrophil cytoplasm antibody (ANCA) fragments from a human v-gene library, Clin Exp Immunol, 93, 21 Mathieson, 1990, Monoclonal antibody therapy in systemic vasculitis, New Engl J Med, 323, 250, 10.1056/NEJM199007263230407 Brownlee, 1993, The effect of preincubation with ion exchange resins on the binding activity of antineutrophil antibodies (ANCA), Clin Exp Immunol, 93, 23 Jayne, 1991, Treatment of systemic vasculitis with pooled intravenous immunoglobulin, Lancet, 337, 1137, 10.1016/0140-6736(91)92797-6 Jayne, 1993, ANCA anti-idiotype antibodies and the treatment of systemic vasculitis with intravenous immunoglobulin, J Autoimmun, 6, 207, 10.1006/jaut.1993.1018 Pall, 1994, Antiidiotypic antibodies against myeloperoxidase antibodies in pooled human immunoglobulin, Clin Exp Immunol, 95, 257, 10.1111/j.1365-2249.1994.tb06520.x Pusey, 1991, Plasma exchange in focal necrotizing glomerulonephritis without anti-GBM antibodies, Kidney Int, 40, 757, 10.1038/ki.1991.272 Jordan, 1989, Intravenous gammaglobulin therapy in systemic lupus erythematosus and immune complex disease, Clin Immunol Immunopathol, 53, S164, 10.1016/0090-1229(89)90082-2 Schifferli, 1991, High dose intravenous IgG treatment and renal function, Lancet, i, 457, 10.1016/0140-6736(91)93395-P