Evidence for a Language Quantitative Trait Locus on Chromosome 7q in Multiplex Autism Families

Aita, 1999, Mapping complex traits in diseases of the hair and skin, Exp Dermatol, 8, 439, 10.1111/j.1600-0625.1999.tb00302.x Alarcón, 2001, QTL mapping of serum IgE in an isolated Hutterite population, Genet Epidemiol, 21, S224, 10.1002/gepi.2001.21.s1.s224 Anderson, 1984, Use of cyclosporin A in establishing Epstein-Barr virus-transformed human lymphoblastoid cell lines, In Vitro, 20, 856, 10.1007/BF02619631 Ashley-Koch, 1999, Genetic studies of autistic disorder and chromosome 7, Genomics, 61, 227, 10.1006/geno.1999.5968 Bailey, 1995, Autism as a strongly genetic disorder: evidence from a British twin study, Psychol Med, 25, 63, 10.1017/S0033291700028099 Barrett, 1999, An autosomal genomic screen for autism: collaborative linkage study of autism, Am J Med Genet, 88, 609, 10.1002/(SICI)1096-8628(19991215)88:6<609::AID-AJMG7>3.0.CO;2-L Bolton, 1994, A case-control family history study of autism, J Child Psychol Psychiatry, 35, 877, 10.1111/j.1469-7610.1994.tb02300.x Bradford, 2001, Incorporating language phenotypes strengthens evidence of linkage to autism, Am J Med Genet, 105, 539, 10.1002/ajmg.1497 Bryson, 1998, Epidemiology of autism: prevalence, associated characteristics, and implications for research and service delivery, Ment Retard, 4, 97, 10.1002/(SICI)1098-2779(1998)4:2<97::AID-MRDD6>3.0.CO;2-U Buxbaum, 2001, Evidence for a susceptibility gene for autism on chromosome 2 and for genetic heterogeneity, Am J Hum Genet, 68, 1514, 10.1086/320588 Conover, 1980 Cook, 2001, Genetics of autism, Child Adolesc Psychiatr Clin N Am, 10, 333, 10.1016/S1056-4993(18)30061-0 Fisher, 1998, Localisation of a gene implicated in a severe speech and language disorder, Nat Genet, 18, 168, 10.1038/ng0298-168 Folstein, 1998, Finding specific genes that cause autism: a combination of approaches will be needed to maximize power, J Autism Dev Disord, 28, 439, 10.1023/A:1026008606672 Folstein, 2000, Chromosome 7q: where autism meets language disorder?, Am J Hum Genet, 67, 278, 10.1086/303034 Folstein, 1999, Predictors of cognitive test patterns in autism families, J Child Psychol Psychiatry, 40, 1117, 10.1111/1469-7610.00528 Geschwind, 2001, The autism genetic resource exchange: a resource for the study of autism and related neuropsychiatric conditions, Am J Hum Genet, 69, 463, 10.1086/321292 Haseman, 1972, The investigation of linkage between a quantitative trait and a marker locus, Behav Genet, 2, 3, 10.1007/BF01066731 Horvath, 2001, The family based association test method: strategies for studying general genotype-phenotype associations, Eur J Hum Genet, 9, 301, 10.1038/sj.ejhg.5200625 IMGSAC, 1998, A full genome screen for autism with evidence for linkage to a region on chromosome 7q. International Molecular Genetic Study of Autism Consortium, Hum Mol Genet, 7, 571, 10.1093/hmg/7.3.571 IMGSAC, 2001, A genomewide screen for autism: strong evidence for linkage to chromosomes 2q, 7q, and 16p, Am J Hum Genet, 69, 570, 10.1086/323264 Kruglyak, 1996, Parametric and nonparametric linkage analysis: a unified multipoint approach, Am J Hum Genet, 58, 1347 Kruglyak, 1995, Complete multipoint sib-pair analysis of qualitative and quantitative traits, Am J Hum Genet, 57, 439 Lai, 2000, The SPCH1 region on human 7q31: genomic characterization of the critical interval and localization of translocations associated with speech and language disorder [see comments], Am J Hum Genet, 67, 357, 10.1086/303011 Lake, 2000, Family-based tests of association in the presence of linkage, Am J Hum Genet, 67, 1515, 10.1086/316895 Lamb, 2000, Autism: recent molecular genetic advances, Hum Mol Genet, 9, 861, 10.1093/hmg/9.6.861 Landa, 1991, Spontaneous narrative-discourse performance of parents of autistic individuals, J Speech Hear Res, 34, 1339, 10.1044/jshr.3406.1339 Landa, 1992, Social language use in parents of autistic individuals, Psychol Med, 22, 245, 10.1017/S0033291700032918 Le Couteur, 1996, A broader phenotype of autism: the clinical spectrum in twins, J Child Psychol Psychiatry, 37, 785, 10.1111/j.1469-7610.1996.tb01475.x Liu, 2001, A genomewide screen for autism susceptibility loci, Am J Hum Genet, 69, 327, 10.1086/321980 Lord, 2001, Quantifying the phenotype in autism spectrum disorders, Am J Med Genet, 105, 36, 10.1002/1096-8628(20010108)105:1<36::AID-AJMG1053>3.0.CO;2-4 Lord, 1994, Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders, J Autism Dev Disord, 24, 659, 10.1007/BF02172145 Maestrini, 2000, Identifying autism susceptibility genes, Neuron, 28, 19, 10.1016/S0896-6273(00)00081-7 O'Connell, 1998, PedCheck: a program for identification of genotype incompatibilities in linkage analysis, Am J Hum Genet, 63, 259, 10.1086/301904 Philippe, 1999, Genome-wide scan for autism susceptibility genes: Paris Autism Research International Sibpair Study, Hum Mol Genet, 8, 805, 10.1093/hmg/8.5.805 Pickles, 1995, Latent-class analysis of recurrence risks for complex phenotypes with selection and measurement error: a twin and family history study of autism, Am J Hum Genet, 57, 717 Piven, 1997, Broader autism phenotype: evidence from a family history study of multiple-incidence autism families, Am J Psychiatry, 154, 185, 10.1176/ajp.154.2.185 Piven, 1994, Personality characteristics of the parents of autistic individuals, Psychol Med, 24, 783, 10.1017/S0033291700027938 Risch, 1999, A genomic screen of autism: evidence for a multilocus etiology, Am J Hum Genet, 65, 493, 10.1086/302497 Smalley, 1988, Autism and genetics, Arch Gen Psychiatr, 45, 953, 10.1001/archpsyc.1988.01800340081013 Smalley, 1995, Autism, affective disorders, and social phobia, Am J Med Genet, 60, 19, 10.1002/ajmg.1320600105 Stoltenberg, 2000, Recent progress in psychiatric genetics-some hope but no hype, Hum Mol Genet, 9, 927, 10.1093/hmg/9.6.927 Warburton, 2000, Support for linkage of autism and specific language impairment to 7q3 from two chromosome rearrangements involving band 7q31, Am J Med Genet, 96, 228, 10.1002/(SICI)1096-8628(20000403)96:2<228::AID-AJMG20>3.0.CO;2-G