Ethanol-induced apoptosis in human liver adenocarcinoma cells (SK-Hep1): Fas- and mitochondria-mediated pathways and interaction with MAPK signaling system

Toxicology in Vitro - Tập 27 - Trang 1820-1829 - 2013
Yuri Morio1, Mayumi Tsuji1, Manami Inagaki1, Mai Nakagawa1, Yuri Asaka1, Hideto Oyamada1, Kanji Furuya1, Katsuji Oguchi1
1Department of Pharmacology, School of Medicine, Showa University, Hatanodai 1-5-8, Shinagawa-ku, Tokyo 142-8555, Japan

Tài liệu tham khảo

Adachi, 2002, Role of mitochondria in alcoholic liver injury, Free Radic. Bio. Med., 32, 487, 10.1016/S0891-5849(02)00740-2 Bedard, 2007, The NOX family of ROS-generating NADPH oxidase: physiology and pathophysiology, Physiol. Rev., 87, 245, 10.1152/physrev.00044.2005 Conde de la Rosa, 2008, Hepatocyte oxidant stress and alcoholic liver disease, Rev. Esp. Enferm. Dig., 100, 156 Frankfurt, 2001, Identification of apoptotic cells by formamide-induced DNA denaturation in condensed chromatin, J. Histochem. Cytochem., 49, 369, 10.1177/002215540104900311 Guichard, 2008, NOX family NADPH oxidases in liver and in pancreatic islets: a role in the metabolic syndrome and diabetes?, Biochem. Soc. Trans., 36, 920, 10.1042/BST0360920 Hennig, 2009, Ethanol-TGF-α-MEK signal promotes growth of human hepatocellular carcinoma, J. Surf. Res., 154, 187, 10.1016/j.jss.2008.11.836 Henzel, 2004, Toxicity of ethanol and acetaldehyde in hepatocytes treated with ursodeoxycholic or tauroursodeoxycholic acid, Biochim. Biophys. Acta, 1644, 37, 10.1016/j.bbamcr.2003.10.017 Hikita, 2009, BH3-only protein bid participates in the Bcl-2 network in healthy liver cells, Hepatology, 50, 1972, 10.1002/hep.23207 Horie, 2009, Current status of alcoholic liver cirrhosis and factors involved in the progression, Kanzo, 50, 507, 10.2957/kanzo.50.507 Ishii, 2003, Role of apoptosis in alcoholic liver injury, Alcohol Clin. Exp. Res., 27, 1207, 10.1111/j.1530-0277.2003.tb02886.x Junttila, 2008, Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival, FASEB J., 22, 954, 10.1096/fj.06-7859rev Kim, 2009, Effects of Asparagus officinails extracts on liver cell toxicity and ethanol metabolism, J. Food Sci., 74, 204, 10.1111/j.1750-3841.2009.01263.x Luo, 1998, Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors, Cell, 94, 481, 10.1016/S0092-8674(00)81589-5 Minana, 2002, Mitochondrial oxidative stress and CD95 ligand: a dual mechanism for hepatocyte apoptosis in chronic alcoholism, Hepatology, 35, 1205, 10.1053/jhep.2002.32969 Mochizuki, 2012, Ethanol increases NADPH oxidase-derived oxidative stress and induces apoptosis in human liver adenocarcinoma cell (SK-HEP-1), Showa Univ. Med. Sci., 24, 155, 10.15369/sujms.24.155 Ota, 2011, Ethanol-induced stress leads to apoptosis via endoplasmic reticulum stress in SK-Hep1 cells, Showa Univ. J. Med. Sci., 23, 23, 10.15369/sujms.23.23 Reinehr, 2005, Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis, J. Biol. Chem., 280, 27179, 10.1074/jbc.M414361200 Sastre, 2007, Mitochondrial function in liver disease, Front Biosci., 12, 1200, 10.2741/2138 Shimizu, 1999, Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC, Nature, 399, 483, 10.1038/20959 Tsuji, M., Oguchi, K., 2012. Some Findings on Apoptosis in Hepatocytes. In: Tobias M. Ntuli (Ed.), Apoptosis and Medicine. InTech, Croatia, pp205-224. <http://www.intechopen.com/books/apoptosis-and-medicine/some-findings-on-apoptosis-in-hepatocytes>. Utanohara, 2005, The effect of ursodeoxycholic acid on glycochenodeoxycholic acid-induced apoptosis in rat hepatocytes, Toxicology, 214, 77, 10.1016/j.tox.2005.05.025 Wajant, 1998, Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction, Curr. Biol., 8, 113, 10.1016/S0960-9822(98)70042-9