Continuous Glibenclamide Prevents Hemorrhagic Transformation in a Rodent Model of Severe Ischemia-Reperfusion

Journal of Stroke and Cerebrovascular Diseases - Tập 30 - Trang 105595 - 2021
Takahiro Igarashi1, Cristina Sastre1, Zoe Wolcott1, W. Taylor Kimberly1
1Division of Neurocritical Care, Center for Genomic Medicine and Department of Neurology, Massachusetts General Hospital, Boston, MA, USA

Tài liệu tham khảo

Broocks, 2019, Clinical benefit of thrombectomy in stroke patients with low ASPECTS is mediated by oedema reduction, Brain, 142, 1399, 10.1093/brain/awz057 Irvine, 2018, Reperfusion after ischemic stroke is associated with reduced brain edema, J Cereb Blood Flow Metab, 38, 1807, 10.1177/0271678X17720559 Thorén, 2020, Effect of recanalization on cerebral edema in ischemic stroke treated with thrombolysis and/or endovascular therapy, Stroke, 51, 216, 10.1161/STROKEAHA.119.026692 Kimberly, 2018, Association of reperfusion with brain edema in patients with acute ischemic stroke: a secondary analysis of the MR CLEAN Trial, JAMA Neurol, 75, 1, 10.1001/jamaneurol.2017.5162 Okada, 1989, Hemorrhagic transformation in cerebral embolism, Stroke, 20, 598, 10.1161/01.STR.20.5.598 Larrue, 1997, Hemorrhagic transformation in acute ischemic stroke. potential contributing factors in the European Cooperative Acute Stroke Study, Stroke., 28, 957, 10.1161/01.STR.28.5.957 Larrue, 2001, Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasminogen activator: a secondary analysis of the European-Australasian Acute Stroke Study (ECASS II), Stroke., 32, 438, 10.1161/01.STR.32.2.438 Goyal, 2011, Effect of baseline CT scan appearance and time to recanalization on clinical outcomes in endovascular thrombectomy of acute ischemic strokes, Stroke, 42, 93, 10.1161/STROKEAHA.110.594481 Berkhemer, 2015, A randomized trial of intraarterial treatment for acute ischemic stroke, N Engl J Med, 372, 11, 10.1056/NEJMoa1411587 Saver, 2015, Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke, N Engl J Med, 372, 2285, 10.1056/NEJMoa1415061 Campbell, 2015, Endovascular therapy for ischemic stroke with perfusion-imaging selection, N Engl J Med, 372, 1009, 10.1056/NEJMoa1414792 Jovin, 2015, Thrombectomy within 8 hours after symptom onset in ischemic stroke, N Engl J Med, 372, 2296, 10.1056/NEJMoa1503780 Jovin, 2011, Imaging-based endovascular therapy for acute ischemic stroke due to proximal intracranial anterior circulation occlusion treated beyond 8 hours from time last seen well: Retrospective multicenter analysis of 237 consecutive patients, Stroke, 42, 2206, 10.1161/STROKEAHA.110.604223 Lansberg, 2012, MRI profile and response to endovascular reperfusion after stroke (DEFUSE 2): a prospective cohort study, Lancet Neurol, 11, 860, 10.1016/S1474-4422(12)70203-X Nogueira, 2017, Thrombectomy 6 to 24 Hours after Stroke with a mismatch between deficit and infarct, N Engl J Med Albers, 2018, Thrombectomy for stroke at 6 to 16 hours with selection by perfusion imaging, N Engl J Med, 378, 708, 10.1056/NEJMoa1713973 Thomalla, 2007, Two tales: hemorrhagic transformation but not parenchymal hemorrhage after thrombolysis is related to severity and duration of ischemia: MRI study of acute stroke patients treated with intravenous tissue plasminogen activator within 6 hours, Stroke, 38, 313, 10.1161/01.STR.0000254565.51807.22 Whiteley, 2016, Risk of intracerebral haemorrhage with alteplase after acute ischaemic stroke: a secondary analysis of an individual patient data meta-analysis, Lancet Neurol, 15, 925, 10.1016/S1474-4422(16)30076-X Román, 2018, Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data, Lancet Neurol, 17, 895, 10.1016/S1474-4422(18)30242-4 Panni, 2019, Acute stroke with large ischemic core treated by thrombectomy, Stroke, 50, 1164, 10.1161/STROKEAHA.118.024295 Nogueira, 2015, Predictors and clinical relevance of hemorrhagic transformation after endovascular therapy for anterior circulation large vessel occlusion strokes: a multicenter retrospective analysis of 1122 patients, J Neurointerv Surg, 7, 16, 10.1136/neurintsurg-2013-010743 Simard, 2006, Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke, Nat Med, 12, 433, 10.1038/nm1390 Simard, 2014, Glibenclamide in cerebral ischemia and stroke, Neurocrit Care, 20, 319, 10.1007/s12028-013-9923-1 Sheth, 2016, Safety and efficacy of intravenous glyburide on brain swelling after large hemispheric infarction (GAMES-RP): a randomised, double-blind, placebo-controlled phase 2 trial, Lancet Neurol, 15, 1160, 10.1016/S1474-4422(16)30196-X Simard, 2007, Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications, Lancet Neurol, 6, 258, 10.1016/S1474-4422(07)70055-8 Simard, 2012, Glibenclamide-10-h treatment window in a clinically relevant model of stroke, Transl Stroke Res, 3, 286, 10.1007/s12975-012-0149-x Simard, 2010, Glibenclamide is superior to decompressive craniectomy in a rat model of malignant stroke, Stroke, 41, 531, 10.1161/STROKEAHA.109.572644 Simard, 2012, Does inhibiting Sur1 complement rt-PA in cerebral ischemia?, Ann N Y Acad Sci, 1268, 95, 10.1111/j.1749-6632.2012.06705.x Gerzanich, 2018, SUR1-TRPM4 channel activation and phasic secretion of MMP-9 induced by tPA in brain endothelial cells, PLoS One, 10.1371/journal.pone.0195526 Kunte, 2012, Hemorrhagic transformation of ischemic stroke in diabetics on sulfonylureas, Ann Neurol, 72, 799, 10.1002/ana.23680 Favilla, 2011, Sulfonylurea use before stroke does not influence outcome, Stroke, 42, 710, 10.1161/STROKEAHA.110.599274 Korninger, 1981, Studies on the specific fibrinolytic effect of human extrinsic (tissue-type) plasminogen activator in human blood and in various animal species in vitro, Thromb Haemost El Amki, 2012, Experimental modeling of recombinant tissue plasminogen activator effects after ischemic stroke, Exp Neurol, 10.1016/j.expneurol.2012.08.005 Tatlisumak, 2006 Sicard, 2009, Animal models of focal brain ischemia, Exp Transl Stroke Med, 1, 7, 10.1186/2040-7378-1-7 Murata, 2008, Extension of the thrombolytic time window with minocycline in experimental stroke, Stroke, 39, 3372, 10.1161/STROKEAHA.108.514026 Sheth, 2014, Pilot study of intravenous glyburide in patients with a large ischemic stroke, Stroke, 45, 281, 10.1161/STROKEAHA.113.003352 Shimamura, 2006, Comparison of silicon-coated nylon suture to plain nylon suture in the rat middle cerebral artery occlusion model, J Neurosci Methods, 156, 161, 10.1016/j.jneumeth.2006.02.017 Bederson, 1986, Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats, Stroke, 17, 1304, 10.1161/01.STR.17.6.1304 Lin, 1993, Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats, Stroke, 24, 117, 10.1161/01.STR.24.1.117 Overgaard, 2000, Influence of different fixation procedures on the quantification of infarction and oedema in a rat model of stroke, Neuropathol Appl Neurobiol, 26, 243, 10.1046/j.1365-2990.2000.00241.x Hosomi, 2005, Tumor necrosis factor-alpha neutralization reduced cerebral edema through inhibition of matrix metalloproteinase production after transient focal cerebral ischemia, J Cereb Blood Flow Metab, 25, 959, 10.1038/sj.jcbfm.9600086 Keep, 2012, Brain water content: a misunderstood measurement?, Transl Stroke Res, 3, 263, 10.1007/s12975-012-0152-2 Hacke, 1995, Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS), JAMA, 274, 1017, 10.1001/jama.1995.03530130023023 Choudhri, 1997, Use of a spectrophotometric hemoglobin assay to objectively quantify intracerebral hemorrhage in mice, Stroke, 28, 2296, 10.1161/01.STR.28.11.2296 Asahi, 2000, Role for matrix metalloproteinase 9 after focal cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94, J Cereb Blood Flow Metab, 20, 1681, 10.1097/00004647-200012000-00007 Simard, 2009, Protective effect of delayed treatment with low-dose glibenclamide in three models of ischemic stroke, Stroke, 40, 604, 10.1161/STROKEAHA.108.522409 Kimberly, 2014, Glyburide is associated with attenuated vasogenic edema in stroke patients, Neurocrit Care, 20, 193, 10.1007/s12028-013-9917-z Zhao, 2007, Neurovascular proteases in brain injury, hemorrhage and remodeling after stroke, Stroke, 38, 748, 10.1161/01.STR.0000253500.32979.d1 Tsuji, 2005, Tissue plasminogen activator promotes matrix metalloproteinase-9 upregulation after focal cerebral ischemia, Stroke, 36, 1954, 10.1161/01.STR.0000177517.01203.eb Wang, 2003, Lipoprotein receptor-mediated induction of matrix metalloproteinase by tissue plasminogen activator, Nat Med, 9, 1313, 10.1038/nm926