Sustained-release from nanocarriers: a review

Hitzman, 2005, Measurement of drug release from microcarriers by microdialysis, J. Pharm. Sci., 94, 1456, 10.1002/jps.20349 Henriksen, 1995, In-vitro evaluation of drug-release kinetics from liposomes by fractional dialysis, Int. J. Pharm., 119, 231, 10.1016/0378-5173(94)00403-R Chidambaram, 1999, A novel in vitro release method for submicron-sized dispersed systems, AAPS PharmSci, 1, 10.1208/ps010311 Shazly, 2008, Comparison of dialysis and dispersion methods for in vitro release determination of drugs from multilamellar liposomes, 1 D'Souza, 2006, Methods to assess in vitro drug release from injectable polymeric particulate systems, Pharm. Res., 23, 460, 10.1007/s11095-005-9397-8 Washington, 1990, Drug release from microdisperse systems: a critical review, Int. J. Pharm., 58, 1, 10.1016/0378-5173(90)90280-H Abdel-Mottaleb, 2011, Standardized in vitro drug release test for colloidal drug carriers using modified USP dissolution apparatus I, Drug Dev. Ind. Pharm., 37, 178, 10.3109/03639045.2010.502534 Gao, 2013, In vitro release kinetics of antituberculosis drugs from nanoparticles assessed using a modified dissolution apparatus, BioMed Res. Int., 2013, 9, 10.1155/2013/136590 Charalampopoulos, 2003, Differential pulse polarography: a suitable technique for monitoring drug release from polymeric nanoparticle dispersions, Anal. Chim. Acta., 491, 57, 10.1016/S0003-2670(03)00788-8 Jara-Ulloa, 2012, Voltammetric determination of nifedipine on carbon nanotubes-modified glassy carbon electrode: A new application to dissolution test studies, Electroanalysis, 24, 1751 Lamprecht, 2002, A quantitative method for the determination of amphiphilic drug release kinetics from nanoparticles using a Langmuir balance, Anal. Chem., 74, 3416, 10.1021/ac025581k Wagner, 2006, The emerging nanomedicine landscape, Nat. Biotechnol., 24, 1211, 10.1038/nbt1006-1211 Vasir, 2007, Biodegradable nanoparticles for cytosolic delivery of therapeutics, Adv. Drug Deliv. Rev., 59, 718, 10.1016/j.addr.2007.06.003 Duncan, 2011, Nanomedicine(s) under the microscope, Mol. Pharm., 8, 2101, 10.1021/mp200394t Matsumura, 1986, A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs, Cancer Res., 46, 6387 Robert, 2004, The role of the liposomal anthracyclines and other systemic therapies in the management of advanced breast cancer, Semin. Oncol., 31, 106, 10.1053/j.seminoncol.2004.09.018 Phillips, 2010, Targeted nanodelivery of drugs and diagnostics, Nano Today, 5, 143, 10.1016/j.nantod.2010.03.003 Green, 2006, Abraxane, a novel cremophor-free, albumin-bound particle form of paclitaxel for the treatment of advanced non-small-cell lung cancer, Ann. Oncol., 17, 1263, 10.1093/annonc/mdl104 Miele, 2009, Albumin-bound formulation of paclitaxel (Abraxane(r) ABI-007) in the treatment of breast cancer, Int. J. Nanomedicine, 4, 99 Okada, 1997, One- and three-month release injectable microspheres of the LH-RH superagonist leuprorelin acetate, Adv. Drug Deliv. Rev., 28, 43, 10.1016/S0169-409X(97)00050-1 Rhee, 2010, Sustained-release injectable drug delivery, Pharm. Technol., s6 Allen, 2013, Liposomal drug delivery systems: From concept to clinical applications, Adv. Drug Deliv. Rev., 65, 36, 10.1016/j.addr.2012.09.037 Barenholz, 2012, Doxil(r) – The first FDA-approved nano-drug: lessons learned, J. Control. Release, 160, 117, 10.1016/j.jconrel.2012.03.020 Danhier, 2012, PLGA-based nanoparticles: an overview of biomedical applications, J. Control. Release, 161, 505, 10.1016/j.jconrel.2012.01.043 Haran, 1993, Transmembrane ammonium-sulfate gradients in liposomes produce efficient and stable entrapment of amphiphatic weak bases, Biochim. Biophys. Acta Biomembr., 1151, 201, 10.1016/0005-2736(93)90105-9 Chang, 2012, Clinical development of liposome-based drugs: Formulation, characterization, and therapeutic efficacy, Int. J. Nanomedicine, 7, 49 Meunier, 1991, Liposomal amphotericin B (AmBisome): safety data from a phase II/III clinical trial, J. Antimicrob. Chemother., 28, 83, 10.1093/jac/28.suppl_B.83 Olson, 2008, Comparison of the physicochemical, antifungal, and toxic properties of two liposomal amphotericin B products, Antimicrob. Agents Chemother., 52, 259, 10.1128/AAC.00870-07 Rivera, 2003, Liposomal anthracyclines in metastatic breast cancer: clinical update, Oncologist, 8, 3, 10.1634/theoncologist.8-suppl_2-3 Park, 2002, Liposome-based drug delivery in breast cancer treatment, Breast Cancer Res., 4, 95, 10.1186/bcr432 Hong, 2004, Liposomal anti-cancer drug researches – The myth of long circulation, J. Chin. Oncol. Soc., 20, 10 Chowdhary, 2003, Drug release characteristics of lipid based benzoporphyrin derivative, J. Pharm. Pharm. Sci., 6, 13 Fahr, 2005, Transfer of lipophilic drugs between liposomal membranes and biological interfaces: consequences for drug delivery, Eur. J. Pharm. Sci., 26, 251, 10.1016/j.ejps.2005.05.012 Usonis, 2003, Antibody titres after primary and booster vaccination of infants and young children with a virosomal hepatitis A vaccine (Epaxal), Vaccine, 21, 4588, 10.1016/S0264-410X(03)00509-7 Herzog, 2009, Eleven years of Inflexal V-a virosomal adjuvanted influenza vaccine, Vaccine, 27, 4381, 10.1016/j.vaccine.2009.05.029 Immordino, 2006, Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential, Int. J. Nanomedicine, 1, 297 Wasan, 1996, Characteristics of lipid-based formulations that influence their biological behavior in the plasma of patients, Clin. Infect. Dis., 23, 1126, 10.1093/clinids/23.5.1126 Guo, 2001, Amphotericin B colloidal dispersion: an improved antifungal therapy, Adv. Drug Deliv. Rev., 47, 149, 10.1016/S0169-409X(01)00104-1 Natarajan, 2014, Sustained drug release in nanomedicine: A long-acting nanocarrier-based formulation for glaucoma, ACS Nano, 8, 419, 10.1021/nn4046024 Huynh, 2009, Lipid nanocapsules: a new platform for nanomedicine, Int. J. Pharm., 379, 201, 10.1016/j.ijpharm.2009.04.026 Natarajan, 2012, Nanomedicine for glaucoma: liposomes provide sustained release of latanoprost in the eye, Int. J. Nanomedicine, 7 Charrois, 2004, Drug release rate influences the pharmacokinetics, biodistribution, therapeutic activity, and toxicity of pegylated liposomal doxorubicin formulations in murine breast cancer, Biochim. Biophys. Acta, 1663, 167, 10.1016/j.bbamem.2004.03.006 Bhardwaj, 2010, Physicochemical properties of extruded and non-extruded liposomes containing the hydrophobic drug dexamethasone, Int. J. Pharm., 388, 181, 10.1016/j.ijpharm.2010.01.003 Dos Santos, 2004, pH gradient loading of anthracyclines into cholesterol-free liposomes: enhancing drug loading rates through use of ethanol, Biochim. Biophys. Acta Biomembr., 1661, 47, 10.1016/j.bbamem.2003.11.016 Gubernator, 2011, Active methods of drug loading into liposomes: recent strategies for stable drug entrapment and increased in vivo activity, Expert Opin. Drug Deliv., 8, 565, 10.1517/17425247.2011.566552 Lasic, 1995, Transmembrane gradient driven phase-transitions within vesicles – lessons for drug delivery, Biochim. Biophys. Acta Biomembr., 1239, 145, 10.1016/0005-2736(95)00159-Z Maurer, 1998, Anomalous solubility behavior of the antibiotic ciprofloxacin encapsulated in liposomes: a H-1-NMR study, Biochim. Biophys. Acta Biomembr., 1374, 9, 10.1016/S0005-2736(98)00125-4 Johnston, 2006, Therapeutically optimized rates of drug release can be achieved by varying the drug-to-lipid ratio in liposomal vincristine formulations, Biochim. Biophys. Acta Biomembr., 1758, 55, 10.1016/j.bbamem.2006.01.009 Johnston, 2008, Influence of drug-to-lipid ratio on drug release properties and liposome integrity in liposomal doxorubicin formulations, J. Liposome Res., 18, 145, 10.1080/08982100802129372 Abrishami, 2009, Preparation, characterization, and in vivo evaluation of nanoliposomes-encapsulated bevacizumab (avastin) for intravitreal administration, Retina J. Retin. Vit. Dis., 29, 699 Bochot, 2012, Liposomes for intravitreal drug delivery: A state of the art, J. Control. Release, 161, 628, 10.1016/j.jconrel.2012.01.019 Katanasaka, 2008, Antiangiogenic cancer therapy using tumor vasculature-targeted liposomes encapsulating 3-(3,5-dimethyl-1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one, SU5416, Cancer Lett., 270, 260, 10.1016/j.canlet.2008.05.009 Gao, 1994, Vasoactive intestinal peptide encapsulated in liposomes: Effects on systemic arterial blood pressure, Life Sci., 54, PL247, 10.1016/0024-3205(94)00425-0 Hwang, 1999, Remote loading of diclofenac, insulin and fluorescein isothiocyanate labeled insulin into liposomes by pH and acetate gradient methods, Int. J. Pharm., 179, 85, 10.1016/S0378-5173(98)00392-5 Kallinteri, 2002, Dexamethasone incorporating liposomes: an in vitro study of their applicability as a slow releasing delivery system of dexamethasone from covered metallic stents, Biomaterials, 23, 4819, 10.1016/S0142-9612(02)00233-8 Liu, 2006, Liposome formulation of a novel hydrophobic aryl-imidazole compound for anti-cancer therapy, Cancer Chemother. Pharmacol., 58, 306, 10.1007/s00280-005-0161-x Ye, 2000, DepoFoam(tm) technology: a vehicle for controlled delivery of protein and peptide drugs, J. Control. Release, 64, 155, 10.1016/S0168-3659(99)00146-7 Schwarz, 1994, Solid lipid nanoparticles (SLN) for controlled drug delivery. I. Production, characterization and sterilization, J. Control. Release, 30, 83, 10.1016/0168-3659(94)90047-7 Gasco, 1992, Timolol in lipospheres, Die Pharmazie, 47, 119 Pardeshi, 2012, Solid lipid based nanocarriers: an overview, Acta Pharm., 62, 433, 10.2478/v10007-012-0040-z Müller, 2000, Solid lipid nanoparticles (SLN) for controlled drug delivery – a review of the state of the art, Eur. J. Pharm. Biopharm., 50, 161, 10.1016/S0939-6411(00)00087-4 Müller, 2002, Nanostructured lipid matrices for improved microencapsulation of drugs, Int. J. Pharm., 242, 121, 10.1016/S0378-5173(02)00180-1 Jenning, 2000, Solid lipid nanoparticles (SLN) based on binary mixtures of liquid and solid lipids: a (1)H-NMR study, Int. J. Pharm., 205, 15, 10.1016/S0378-5173(00)00462-2 Das, 2012, Are nanostructured lipid carriers (NLCs) better than solid lipid nanoparticles (SLNs): Development, characterizations and comparative evaluations of clotrimazole-loaded SLNs and NLCs?, Eur. J. Pharm. Sci., 47, 139, 10.1016/j.ejps.2012.05.010 zur Mühlen, 1998, Solid lipid nanoparticles (SLN) for controlled drug delivery--drug release and release mechanism, Eur. J. Pharm. Biopharm., 45, 149, 10.1016/S0939-6411(97)00150-1 Almeida, 2007, Solid lipid nanoparticles as a drug delivery system for peptides and proteins, Adv. Drug Deliv. Rev., 59, 478, 10.1016/j.addr.2007.04.007 Saraf, 2006, Lipid microparticles for mucosal immunization against hepatitis B, Vaccine, 24, 45, 10.1016/j.vaccine.2005.07.053 Ribeiro Dos Santos, 2002, Microencapsulation of protein particles within lipids using a novel supercritical fluid process, Int. J. Pharm., 242, 69, 10.1016/S0378-5173(02)00149-7 Almeida, 1997, Peptide-loaded solid lipid nanoparticles (SLN): Influence of production parameters, Int. J. Pharm., 149, 255, 10.1016/S0378-5173(97)04885-0 Garcia-Fuentes, 2005, New surface-modified lipid nanoparticles as delivery vehicles for salmon calcitonin, Int. J. Pharm., 296, 122, 10.1016/j.ijpharm.2004.12.030 Müller, 2006, Oral bioavailability of cyclosporine: solid lipid nanoparticles (SLN) versus drug nanocrystals, Int. J. Pharm., 317, 82, 10.1016/j.ijpharm.2006.02.045 Trotta, 2005, Solid lipid micro-particles carrying insulin formed by solvent-in-water emulsion-diffusion technique, Int. J. Pharm., 288, 281, 10.1016/j.ijpharm.2004.10.014 Zhang, 2006, Lectin-modified solid lipid nanoparticles as carriers for oral administration of insulin, Int. J. Pharm., 327, 153, 10.1016/j.ijpharm.2006.07.026 Reithmeier, 2001, Development and characterization of lipid microparticles as a drug carrier for somatostatin, Int. J. Pharm., 218, 133, 10.1016/S0378-5173(01)00620-2 Hu, 2004, Preparation and characterization of solid lipid nanoparticles containing peptide, Int. J. Pharm., 273, 29, 10.1016/j.ijpharm.2003.12.016 Yuan, 2009, Strategic approaches for improving entrapment of hydrophilic peptide drugs by lipid nanoparticles, Colloids Surf. B: Biointerfaces, 70, 248, 10.1016/j.colsurfb.2008.12.031 Li, 2010, Yak interferon-alpha loaded solid lipid nanoparticles for controlled release, Res. Vet. Sci., 88, 148, 10.1016/j.rvsc.2009.06.010 Kumari, 2010, Biodegradable polymeric nanoparticles based drug delivery systems, Colloids Surf. B: Biointerfaces, 75, 1, 10.1016/j.colsurfb.2009.09.001 Soppimath, 2001, Biodegradable polymeric nanoparticles as drug delivery devices, J. Control. Release, 70, 1, 10.1016/S0168-3659(00)00339-4 Hans, 2002, Biodegradable nanoparticles for drug delivery and targeting, Curr. Opinion Solid State Mater. Sci., 6, 319, 10.1016/S1359-0286(02)00117-1 Mundargi, 2008, Nano/micro technologies for delivering macromolecular therapeutics using poly(D, L-lactide-co-glycolide) and its derivatives, J. Control. Release, 125, 193, 10.1016/j.jconrel.2007.09.013 Leo, 2004, In vitro evaluation of PLA nanoparticles containing a lipophilic drug in water-soluble or insoluble form, Int. J. Pharm., 278, 133, 10.1016/j.ijpharm.2004.03.002 Chitosan, 2003, Nanoparticles: A promising system for drug delivery, Naresuan Univ. J., 11, 51 Pinto Reis, 2006, Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles, Nanomedicine, 2, 8, 10.1016/j.nano.2005.12.003 Zambaux, 1999, Preparation and characterization of protein C-loaded PLA nanoparticles, J. Control. Release, 60, 179, 10.1016/S0168-3659(99)00073-5 Sahana, 2008, PLGA nanoparticles for oral delivery of hydrophobic drugs: influence of organic solvent on nanoparticle formation and release behavior in vitro and in vivo using estradiol as a model drug, J. Pharm. Sci., 97, 1530, 10.1002/jps.21158 Barichello, 1999, Encapsulation of hydrophilic and lipophilic drugs in PLGA nanoparticles by the nanoprecipitation method, Drug Dev. Ind. Pharm., 25, 471, 10.1081/DDC-100102197 Mu, 2003, A novel controlled release formulation for the anticancer drug paclitaxel (Taxol): PLGA nanoparticles containing vitamin E TPGS, J. Control. Release, 86, 33, 10.1016/S0168-3659(02)00320-6 Labhasetwar, 1998, Arterial uptake of biodegradable nanoparticles: effect of surface modifications, J. Pharm. Sci., 87, 1229, 10.1021/js980021f Derakhshandeh, 2007, Encapsulation of 9-nitrocamptothecin, a novel anticancer drug, in biodegradable nanoparticles: factorial design, characterization and release kinetics, Eur. J. Pharm. Biopharm., 66, 34, 10.1016/j.ejpb.2006.09.004 Murakami, 1999, Preparation of poly(DL-lactide-co-glycolide) nanoparticles by modified spontaneous emulsification solvent diffusion method, Int. J. Pharm., 187, 143, 10.1016/S0378-5173(99)00187-8 Beletsi, 2008, Simultaneous optimization of cisplatin-loaded PLGA-mPEG nanoparticles with regard to their size and drug encapsulation, Curr. Nanosci., 4, 173, 10.2174/157341308784340895 Desai, 2000, Immune response with biodegradable nanospheres and alum: studies in rabbits using staphylococcal enterotoxin B-toxoid, J. Microencapsul., 17, 215, 10.1080/026520400288454 Cohen, 2000, Sustained delivery and expression of DNA encapsulated in polymeric nanoparticles, Gene Ther., 7, 1896, 10.1038/sj.gt.3301318 Dunn, 1997, In vitro cell interaction and in vivo biodistribution of poly(lactide-co-glycolide) nanospheres surface modified by poloxamer and poloxamine copolymers, J. Control. Release, 44, 65, 10.1016/S0168-3659(96)01504-0 De Jaeghere, 1999, Formulation and lyoprotection of Poly(Lactic Acid-Co-Ethylene Oxide) nanoparticles: Influence on physical stability and in vitro cell uptake, Pharm. Res., 16, 859, 10.1023/A:1018826103261 Gref, 1994, Biodegradable long-circulating polymeric nanospheres, Science, 263, 1600, 10.1126/science.8128245 Peracchia, 1997, Complement consumption by poly(ethylene glycol) in different conformations chemically coupled to poly(isobutyl 2-cyanoacrylate) nanoparticles, Life Sci., 61, 749, 10.1016/S0024-3205(97)00539-0 Leroux, 1996, Biodegradable nanoparticles – From sustained release formulations to improved site specific drug delivery, J. Control. Release, 39, 339, 10.1016/0168-3659(95)00164-6 Allemann, 1993, In vitro extended-release properties of drug-loaded poly(DL-lactic acid) nanoparticles produced by a salting-out procedure, Pharm. Res., 10, 1732, 10.1023/A:1018970030327 Prabu, 2009, Preparation, characterization, in-vitro drug release and cellular uptake of poly(caprolactone) grafted dextran copolymeric nanoparticles loaded with anticancer drug, J. Biomed. Mater. Res. A, 90, 1128, 10.1002/jbm.a.32163 Danhier, 2009, Paclitaxel-loaded PEGylated PLGA-based nanoparticles: in vitro and in vivo evaluation, J. Control. Release, 133, 11, 10.1016/j.jconrel.2008.09.086 Liang, 2011, Improved therapeutic effect of folate-decorated PLGA-PEG nanoparticles for endometrial carcinoma, Bioorg. Med. Chem., 19, 4057, 10.1016/j.bmc.2011.05.016 Song, 1997, Formulation and characterization of biodegradable nanoparticles for intravascular local drug delivery, J. Control. Release, 43, 197, 10.1016/S0168-3659(96)01484-8 Guzman, 1996, Local intraluminal infusion of biodegradable polymeric nanoparticles. A novel approach for prolonged drug delivery after balloon angioplasty, Circulation, 94, 1441, 10.1161/01.CIR.94.6.1441 Suzuki, 2001, Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model, Circulation, 104, 1188, 10.1161/hc3601.093987 Grube, 2003, TAXUS I: six- and twelve-month results from a randomized, double-blind trial on a slow-release paclitaxel-eluting stent for de novo coronary lesions, Circulation, 107, 38, 10.1161/01.CIR.0000047700.58683.A1 Venkatraman, 2007, Release profiles in drug-eluting stents: issues and uncertainties, J. Control. Release, 120, 149, 10.1016/j.jconrel.2007.04.022 Delcea, 2011, Stimuli-responsive LbL capsules and nanoshells for drug delivery, Adv. Drug Deliv. Rev., 63, 730, 10.1016/j.addr.2011.03.010 Labouta, 2010, Tailor-made biofunctionalized nanoparticles using layer-by-layer technology, Int. J. Pharm., 395, 236, 10.1016/j.ijpharm.2010.05.019 Vergaro, 2011, Drug-loaded polyelectrolyte microcapsules for sustained targeting of cancer cells, Adv. Drug Deliv. Rev., 63, 847, 10.1016/j.addr.2011.05.007 Ariga, 2011, Layer-by-layer self-assembled shells for drug delivery, Adv. Drug Deliv. Rev., 63, 762, 10.1016/j.addr.2011.03.016 Haidar, 2008, Protein release kinetics for core-shell hybrid nanoparticles based on the layer-by-layer assembly of alginate and chitosan on liposomes, Biomaterials, 29, 1207, 10.1016/j.biomaterials.2007.11.012 Fukui, 2009, The preparation of sugar polymer-coated nanocapsules by the layer-by-layer deposition on the liposome, Langmuir, 25, 10020, 10.1021/la9008834 Deng, 2013, Layer-by-layer nanoparticles for systemic codelivery of an anticancer drug and siRNA for potential triple-negative breast cancer treatment, ACS Nano, 7, 9571, 10.1021/nn4047925 Feng, 2013, Polyelectrolyte multilayer functionalized mesoporous silica nanoparticles for pH-responsive drug delivery: layer thickness-dependent release profiles and biocompatibility, J. Mater. Chem. B, 1, 5886, 10.1039/c3tb21193b Bazylinska, 2011, Novel approach to long sustained multilayer nanocapsules: influence of surfactant head groups and polyelectrolyte layer number on the release of hydrophobic compounds, Soft Matter, 7, 6113, 10.1039/c1sm05395g Bazylińska, 2012, Influence of pH upon in vitro sustained dye-release from oil-core nanocapsules with multilayer shells, Colloids Surf. A Physicochem. Eng. Asp., 413, 266, 10.1016/j.colsurfa.2011.12.006 Bazylińska, 2012, Influence of dicephalic ionic surfactant interactions with oppositely charged polyelectrolyte upon the in vitro dye release from oil core nanocapsules, Bioelectrochemistry, 87, 147, 10.1016/j.bioelechem.2011.10.006 Zhou, 2009, Polyelectrolyte coated PLGA nanoparticles: templation and release behavior, Macromol. Biosci., 9, 326, 10.1002/mabi.200800188 Nugraha, 2014, Release retardation of model protein on polyelectrolyte-coated PLGA nano- and microparticles, PLoS ONE, 9, e92393, 10.1371/journal.pone.0092393 Luo, 2012, Surface functionalization of nanoparticles to control cell interactions and drug release, Small, 8, 2585, 10.1002/smll.201200398 Morton, 2013, The architecture and biological performance of drug-loaded LbL nanoparticles, Biomaterials, 34, 5328, 10.1016/j.biomaterials.2013.03.059 Liu, 2011, Sacrificial functional polystyrene template to prepare chitosan nanocapsules and in vitro drug release properties, J. Mater. Sci., 46, 6758, 10.1007/s10853-011-5632-3 Wang, 2008, Templated synthesis of single-component polymer capsules and their application in drug delivery, Nano Lett., 8, 1741, 10.1021/nl080877c Huang, 2009, Controlled release of repifermin from polyelectrolyte complexes stimulates endothelial cell proliferation, J. Pharm. Sci., 98, 268, 10.1002/jps.21412 Petchsangsai, 2011, A water-soluble methylated N-(4-N, N-dimethylaminocinnamyl) chitosan chloride as novel mucoadhesive polymeric nanocomplex platform for sustained-release drug delivery, Carbohydr. Polym., 83, 1263, 10.1016/j.carbpol.2010.09.033 Santo, 2012, Chitosan-chondroitin sulphate nanoparticles for controlled delivery of platelet lysates in bone regenerative medicine, J. Tissue Eng. Regen. Med., 6, s47, 10.1002/term.1519 Xiong, 2012, Amphiphilic cholic-acid-modified dextran sulfate and its application for the controlled delivery of superoxide dismutase, Macromol. Biosci., 12, 515, 10.1002/mabi.201100367 Guo, 2013, Novel alginate coated hydrophobically modified chitosan polyelectrolyte complex for the delivery of BSA, J. Mater. Sci. Mater. Med., 24, 2093, 10.1007/s10856-013-4977-3 Raveendran, 2013, Bacterial exopolysaccharide based nanoparticles for sustained drug delivery, cancer chemotherapy and bioimaging, Carbohydr. Polym., 91, 22, 10.1016/j.carbpol.2012.07.079 Jung, 2013, Temperature-modulated noncovalent interaction controllable complex for the long-term delivery of etanercept to treat rheumatoid arthritis, J. Control. Release, 171, 143, 10.1016/j.jconrel.2013.07.012 Zhao, 2013, Calcium phosphate hybrid nanoparticles: self-assembly formation, characterization, and application as an anticancer drug nanocarrier, Chem. Asian. J., 8, 1306, 10.1002/asia.201300083 Fattahi, 2013, Microencapsulation of chemotherapeutics into monodisperse and tunable biodegradable polymers via electrified liquid jets: Control of size, shape, and drug release, Adv. Mater., 25, 4555, 10.1002/adma.201301033 Champion, 2007, Particle shape: a new design parameter for micro- and nanoscale drug delivery carriers, J. Control. Release, 121, 3, 10.1016/j.jconrel.2007.03.022 Champion, 2006, Role of target geometry in phagocytosis, Proc. Natl. Acad. Sci. U. S. A., 103, 4930, 10.1073/pnas.0600997103 Abidian, 2006, Conducting-polymer nanotubes for controlled drug release, Adv. Mater., 18, 405, 10.1002/adma.200501726 Liu, 2008, Drug delivery with carbon nanotubes for in vivo cancer treatment, Cancer Res., 68, 6652, 10.1158/0008-5472.CAN-08-1468 Liu, 2007, Supramolecular chemistry on water-soluble carbon nanotubes for drug loading and delivery, ACS Nano, 1, 50, 10.1021/nn700040t Liu, 2013, Understanding the toxicity of carbon nanotubes, Acc. Chem. Res., 46, 702, 10.1021/ar300028m