A new amide from the leaves and twigs of Litsea auriculata

Journal of Natural Medicines - Tập 63 - Trang 331-334 - 2009
Hitoshi Tanaka1, Saya Yatsuhashi1, Tadashi Yasuda2, Masaru Sato2, Eiji Sakai3, Chen Xiao4, Hiroko Murata5, Jin Murata6
1Faculty of Pharmacy, Meijo University, Nagoya, Japan
2Departments of Periodontology and Oral Pathology, Asahi University School of Dentistry, Gifu, Japan
3Gifu Pharmaceutical University, Gifu, Japan
4Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China
5Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, Japan
6Botanical Gardens, Graduate School of Science, The University of Tokyo, Tokyo, Japan

Tóm tắt

A new amide, N-trans-sinapoylmethoxytyramine (1), along with three known amides (2–4) and two known flavonol 3-O-rhamnosides (5 and 6), were isolated from the leaves and twigs of Litsea auriculata. The structures of the isolated compounds (1–6) were characterized on the basis of spectroscopic analyses, and their cytotoxic activity against HeLa cells was estimated.

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