Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

Mechanisms of Ageing and Development - Tập 191 - Trang 111316 - 2020
Alan A. Cohen1, Brian K. Kennedy2,3,4,5, Ulrich Anglas6,7, Anne M. Bronikowski8, Joris Deelen9,10, Frédérik Dufour1, Gerardo Ferbeyre11, Luigi Ferrucci12, Claudio Franceschi13,14,15, Daniela Frasca16, Bertrand Friguet17, Pierrette Gaudreau11,18, Vadim N. Gladyshev19, Efstathios S. Gonos20, Vera Gorbunova21, Philipp Gut22, Mikhail Ivanchenko23, Véronique Legault1, Jean-François Lemaître24, Thomas Liontis6,7
1Groupe de recherche PRIMUS, Department of Family Medicine, University of Sherbrooke, 3001 12e Ave N, Sherbrooke, QC J1H 5N4, Canada
2Departments of Biochemistry and Physiology, Yong Loo Lin School of Medicine, National University of Singapore, MD 7, 8 Medical Drive, 117596, Singapore
3National University Health System (NUHS) Centre for Healthy Longevity, 1E Kent Ridge Road, 119228, Singapore
4Singapore Institute of Clinical Sciences, A⁎STAR, Brenner Center for Molecular Medicine, 30 Medical Dr., 117609, Singapore
5Buck Institute for Research on Ageing, 8001 Redwood Blvd, Novato, CA, 94945, United States
6Department of Neurology and Neurosurgery, McGill University, 3801 University Street, Montreal, QC, H3A 2B4, Canada
7Metabolic Disorders and Complications Program, and Brain Repair and Integrative Neuroscience Program, Research Institute of the McGill University Health Centre, 1001 Decarie Boulevard, Montreal, Quebec, H4A 3J1, Canada
8Department of Ecology, Evolution, and Organismal Biology, Iowa State University, Ames, IA, 50011, United States
9Max Planck Institute for Biology of Ageing, PO Box 41 06 23, 50866, Cologne, Germany
10Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, PO Box 9600, 2300 RC, Leiden, the Netherlands
11Centre De Recherche Du Centre Hospitalier De l'Université De Montréal (CRCHUM), 900 Saint-Denis St, Montréal, QC, H2X 0A9, Canada
12Translational Gerontology Branch, Longitudinal Studies Section, National Institute on Aging, National Institutes of Health, MedStar Harbor Hospital, 3001 S. Hanover Street, Baltimore, MD, 21225, United States
13Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, 33 Via Zamboni, Bologna, 40126 BO, Italy
14IRCCS Istituto Delle Scienze Neurologiche Di Bologna, Padiglione G, 3 Via Altura, Bologna, 40139, BO, Italy
15Department of Applied Mathematics, Institute of Information Technology, Mathematics and Mechanics (ITMM), Lobachevsky State University of Nizhny Novgorod-National Research University (UNN), 23 Gagarin Avenue, 603950, Nizhnij Novgorod, Russia
16Department of Microbiology and Immunology, University of Miami Miller School of Medicine, 1600 NW 10th Ave, Miami, FL, 33136, United States
17Sorbonne Université, CNRS, INSERM, Institut de Biologie Paris-Seine, Biological Adaptation and Aging, B2A-IBPS, F-75005, Paris, France
18Department of Medicine, Université De Montréal, 2900, Boul. Édouard-Montpetit, Montréal, QC, H3T 1J4, Canada
19Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA, 02115, United States
20Institute of Chemical Biology, National Hellenic Research Foundation, 48 Vassileos Constantinou Ave., Athens, 11635, Greece
21University of Rochester, Department of Biology, Rochester, NY, 14627, United States
22Nestlé Research, Nestlé Institute of Health Sciences, EPFL Innovation Park, 1015, Lausanne, Switzerland
23Department of Applied Mathematics, Lobachevsky State University of Nizhny Novgorod, 603950, Nizhny Novgorod, Russia
24Université de Lyon, Université Lyon 1, CNRS, Laboratoire de Biométrie et Biologie Evolutive UMR5558, F-69622 Villeurbanne, France

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Mechanisms of Ageing and Development

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