Lipidomic Profiling of Influenza Infection Identifies Mediators that Induce and Resolve Inflammation

Cell - Tập 154 - Trang 213-227 - 2013
Vincent C. Tam1, Oswald Quehenberger2,3, Christine M. Oshansky4, Rosa Suen1, Aaron M. Armando5,3, Piper M. Treuting6, Paul G. Thomas4, Edward A. Dennis5,3, Alan Aderem1
1Seattle Biomedical Research Institute, Seattle, WA 98109, USA
2Department of Medicine, University of California San Diego, La Jolla, CA 92093, USA
3Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA
4Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA
5Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093 USA
6Department of Comparative Medicine, University of Washington, Seattle, WA 98195, USA

Tài liệu tham khảo

Allan, 1990, Cellular events in the lymph node and lung of mice with influenza. Consequences of depleting CD4+ T cells, J. Immunol., 144, 3980, 10.4049/jimmunol.144.10.3980 Altmann, 2007, 13-Oxo-ODE is an endogenous ligand for PPARgamma in human colonic epithelial cells, Biochem. Pharmacol., 74, 612, 10.1016/j.bcp.2007.05.027 Ariel, 2007, Resolvins and protectins in the termination program of acute inflammation, Trends Immunol., 28, 176, 10.1016/j.it.2007.02.007 Bannenberg, 2005, Molecular circuits of resolution: formation and actions of resolvins and protectins, J. Immunol., 174, 4345, 10.4049/jimmunol.174.7.4345 Belvisi, 2009, Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease, Br. J. Pharmacol., 158, 994, 10.1111/j.1476-5381.2009.00373.x Buczynski, 2009, Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology, J. Lipid Res., 50, 1015, 10.1194/jlr.R900004-JLR200 Chiang, 2012, Infection regulates pro-resolving mediators that lower antibiotic requirements, Nature, 484, 524, 10.1038/nature11042 Dennis, 2010, A mouse macrophage lipidome, J. Biol. Chem., 285, 39976, 10.1074/jbc.M110.182915 Drake, 2008, Thematic review series: skin lipids. Antimicrobial lipids at the skin surface, J. Lipid Res., 49, 4, 10.1194/jlr.R700016-JLR200 Dumlao, 2011, High-throughput lipidomic analysis of fatty acid derived eicosanoids and N-acylethanolamines, Biochim. Biophys. Acta, 1811, 724, 10.1016/j.bbalip.2011.06.005 Francis, 1945, Combined infection of Mice with H. influenzae and influenza virus by the intranasal route, J. Infect. Dis., 76, 70, 10.1093/infdis/76.1.70 Godson, 2000, Cutting edge: lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages, J. Immunol., 164, 1663, 10.4049/jimmunol.164.4.1663 Hattori, 2008, G2A plays proinflammatory roles in human keratinocytes under oxidative stress as a receptor for 9-hydroxyoctadecadienoic acid, J. Invest. Dermatol., 128, 1123, 10.1038/sj.jid.5701172 Ishizaki, 1995, Leukotoxin, 9,10-epoxy-12-octadecenoate causes edematous lung injury via activation of vascular nitric oxide synthase, Am. J. Physiol., 269, L65 Ishizaki, 1999, Leukotoxins and the lung, Pulm. Pharmacol. Ther., 12, 145, 10.1006/pupt.1999.0179 Jagger, 2012, An overlapping protein-coding region in influenza A virus segment 3 modulates the host response, Science, 337, 199, 10.1126/science.1222213 Jankov, 2002, Hepoxilin analogs inhibit bleomycin-induced pulmonary fibrosis in the mouse, J. Pharmacol. Exp. Ther., 301, 435, 10.1124/jpet.301.2.435 Ji, 2011, Emerging roles of resolvins in the resolution of inflammation and pain, Trends Neurosci., 34, 599, 10.1016/j.tins.2011.08.005 Kash, 2006, Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus, Nature, 443, 578, 10.1038/nature05181 Kiss, 2000, Synthesis of arachidonic acid-derived lipoxygenase and cytochrome P450 products in the intact human lung vasculature, Am. J. Respir. Crit. Care Med., 161, 1917, 10.1164/ajrccm.161.6.9906058 Krönke, 2009, 12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis, J. Immunol., 183, 3383, 10.4049/jimmunol.0900327 Kühn, 2006, Inflammation and immune regulation by 12/15-lipoxygenases, Prog. Lipid Res., 45, 334, 10.1016/j.plipres.2006.02.003 Kühn, 2002, Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications, Prostaglandins Other Lipid Mediat., 68-69, 263, 10.1016/S0090-6980(02)00035-7 Levy, 2007, Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness, J. Immunol., 178, 496, 10.4049/jimmunol.178.1.496 Morgan, 2010, Thrombin-activated human platelets acutely generate oxidized docosahexaenoic-acid-containing phospholipids via 12-lipoxygenase, Biochem. J., 431, 141, 10.1042/BJ20100415 Morita, 2013, The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza, Cell, 153, 112, 10.1016/j.cell.2013.02.027 Neumann, 2009, Emergence and pandemic potential of swine-origin H1N1 influenza virus, Nature, 459, 931, 10.1038/nature08157 Obinata, 2009, G2A as a receptor for oxidized free fatty acids, Prostaglandins Other Lipid Mediat., 89, 66, 10.1016/j.prostaglandins.2008.11.002 O’Flaherty, 2012, 15-lipoxygenase metabolites of docosahexaenoic acid inhibit prostate cancer cell proliferation and survival, PLoS ONE, 7, e45480, 10.1371/journal.pone.0045480 Quehenberger, 2011, The human plasma lipidome, N. Engl. J. Med., 365, 1812, 10.1056/NEJMra1104901 Quehenberger, 2010, Lipidomics reveals a remarkable diversity of lipids in human plasma, J. Lipid Res., 51, 3299, 10.1194/jlr.M009449 Ricote, 1998, The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation, Nature, 391, 79, 10.1038/34178 Sato, 2000, Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction, Immunity, 13, 539, 10.1016/S1074-7613(00)00053-4 Serhan, 1995, Design of lipoxin A4 stable analogs that block transmigration and adhesion of human neutrophils, Biochemistry, 34, 14609, 10.1021/bi00044a041 Serhan, 2000, Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing, J. Exp. Med., 192, 1197, 10.1084/jem.192.8.1197 Serhan, 2008, Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators, Nat. Rev. Immunol., 8, 349, 10.1038/nri2294 Sisemore, 2001, Cellular characterization of leukotoxin diol-induced mitochondrial dysfunction, Arch. Biochem. Biophys., 392, 32, 10.1006/abbi.2001.2434 Spiteller, 1997, 9-Hydroxy-10,12-octadecadienoic acid (9-HODE) and 13-hydroxy-9,11-octadecadienoic acid (13-HODE): excellent markers for lipid peroxidation, Chem. Phys. Lipids, 89, 131, 10.1016/S0009-3084(97)00070-4 Taubenberger, 2010, Influenza virus evolution, host adaptation, and pandemic formation, Cell Host Microbe, 7, 440, 10.1016/j.chom.2010.05.009 Thomson, 2012, Anti-inflammatory effects of epoxyeicosatrienoic acids, Int. J. Vasc. Med., 2012, 605101 Tobin, 2012, Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections, Cell, 148, 434, 10.1016/j.cell.2011.12.023 Totani, 2000, Leukotoxin and its diol induce neutrophil chemotaxis through signal transduction different from that of fMLP, Eur. Respir. J., 15, 75, 10.1183/09031936.00.15107500 Wray, 2009, The epoxygenases CYP2J2 activates the nuclear receptor PPARalpha in vitro and in vivo, PLoS ONE, 4, e7421, 10.1371/journal.pone.0007421 Ahluwalia, 1994, Anti-inflammatory effect of prostanoids in mouse and rat skin: evidence for a role of EP3-receptors, J. Pharmacol. Exp. Ther., 268, 1526 Bednar, 2000, 16(R)-hydroxyeicosatetraenoic acid, a novel cytochrome P450 product of arachidonic acid, suppresses activation of human polymorphonuclear leukocyte and reduces intracranial pressure in a rabbit model of thromboembolic stroke, Neurosurgery, 47, 1410, 10.1097/00006123-200012000-00029 Bittleman, 1995, 5-Hydroxyeicosatetraenoic acid (HETE)-induced neutrophil transcellular migration is dependent upon enantiomeric structure, Am. J. Respir. Cell Mol. Biol., 12, 260, 10.1165/ajrcmb.12.3.7873191 Deng, 2010, Cytochrome P450 epoxygenases, soluble epoxide hydrolase, and the regulation of cardiovascular inflammation, J. Mol. Cell. Cardiol., 48, 331, 10.1016/j.yjmcc.2009.10.022 Emerson, 2004, Experimental allergic encephalomyelitis is exacerbated in mice deficient for 12/15-lipoxygenase or 5-lipoxygenase, Brain Res., 1021, 140, 10.1016/j.brainres.2004.06.045 Fang, 2006, 14,15-Dihydroxyeicosatrienoic acid activates peroxisome proliferator-activated receptor-alpha, Am. J. Physiol. Heart Circ. Physiol., 290, H55, 10.1152/ajpheart.00427.2005 Fritsche, 2008, Too much linoleic acid promotes inflammation-doesn’t it?, Prostaglandins Leukot. Essent. Fatty Acids, 79, 173, 10.1016/j.plefa.2008.09.019 Gereke, 2007, Phenotypic alterations in type II alveolar epithelial cells in CD4+ T cell mediated lung inflammation, Respir. Res., 8, 47, 10.1186/1465-9921-8-47 Groeger, 2010, Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids, Nat. Chem. Biol., 6, 433, 10.1038/nchembio.367 Holtzman, 1992, Arachidonic acid metabolism in airway epithelial cells, Annu. Rev. Physiol., 54, 303, 10.1146/annurev.ph.54.030192.001511 Lee, 2010, Prostaglandin A2 activates intrinsic apoptotic pathway by direct interaction with mitochondria in HL-60 cells, Prostaglandins Other Lipid Mediat., 91, 30, 10.1016/j.prostaglandins.2009.12.003 Lima-Garcia, 2011, The precursor of resolvin D series and aspirin-triggered resolvin D1 display anti-hyperalgesic properties in adjuvant-induced arthritis in rats, Br. J. Pharmacol., 164, 278, 10.1111/j.1476-5381.2011.01345.x Liu, 1994, Prostaglandin B2-induced pulmonary hypertension is mediated by TxA2/PGH2 receptor stimulation, Am. J. Physiol., 267, L602 Marsh, 2009, Surface expression of CD74 by type II alveolar epithelial cells: a potential mechanism for macrophage migration inhibitory factor-induced epithelial repair, Am. J. Physiol. Lung Cell. Mol. Physiol., 296, L442, 10.1152/ajplung.00525.2007 Morin, 2008, EET displays anti-inflammatory effects in TNF-alpha stimulated human bronchi: putative role of CPI-17, Am. J. Respir. Cell Mol. Biol., 38, 192, 10.1165/rcmb.2007-0232OC Peters-Golden, 2006, Cysteinyl leukotrienes: multi-functional mediators in allergic rhinitis, Clin. Exp. Allergy, 36, 689, 10.1111/j.1365-2222.2006.02498.x Sheibanie, 2007, The proinflammatory effect of prostaglandin E2 in experimental inflammatory bowel disease is mediated through the IL-23—>IL-17 axis, J. Immunol., 178, 8138, 10.4049/jimmunol.178.12.8138 Snelgrove, 2008, A critical function for CD200 in lung immune homeostasis and the severity of influenza infection, Nat. Immunol., 9, 1074, 10.1038/ni.1637 Stoll, 1994, 13-HODE increases intracellular calcium in vascular smooth muscle cells, Am. J. Physiol., 266, C990, 10.1152/ajpcell.1994.266.4.C990 Storer, 2005, Cyclopentenone prostaglandins PGA2 and 15-deoxy-delta12,14 PGJ2 suppress activation of murine microglia and astrocytes: implications for multiple sclerosis, J. Neurosci. Res., 80, 66, 10.1002/jnr.20413