MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

Nature - Tập 456 Số 7224 - Trang 980-984 - 2008
Thomas Thum1, Carina Gross2, Jan Fiedler3, Thomas Fischer2, Stephan Kissler2, Markus Bussen4, Paolo Galuppo3, Steffen Just5, Wolfgang Rottbauer5, Stefan Frantz3, M. Castoldi6, Jürgen Soutschek7, Victor Koteliansky8, Andreas Rosenwald9, M. Albert Basson10, Jonathan D. Licht11, John T. R. Pena12, Sara H. Rouhanifard12, Martina U. Muckenthaler6, Thomas Tuschl12, Gail R. Martin4, Johann Bauersachs3, Stefan Engelhardt13,2
1Department of Medicine I, Interdisziplinäres Zentrum für Klinische Forschung (IZKF), University of Wuerzburg, 97080 Wuerzburg, Germany.
2Rudolf Virchow Center, Deutsche Forschungsgemeinschaft (DFG) Research Center for Experimental Biomedicine;
3Department of Medicine I
4Department of Anatomy, University of California, San Francisco, California 94158, USA.
5Department of Internal Medicine III
6Molecular Medicine Partnership Unit, University of Heidelberg, 69120 Heidelberg, Germany
7Regulus Therapeutics, Carlsbad, California 92008, USA ,
8Alnylam Pharmaceuticals, Cambridge, Massachusetts 02142, USA ,
9Institute of Pathology, University of Wuerzburg, 97080 Wuerzburg, Germany.
10Department of Craniofacial Development, King's College, London, SE1 9RT, UK.
11Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA.
12Laboratory of RNA Molecular Biology, Rockefeller University, New York, New York 10065, USA ,
13Institute of Pharmacology and Toxicology, Technische Universitaet Muenchen (TUM), 80802 Muenchen, Germany

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Nature

Tập 456 Số 7224

980-984

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