The Relationship Between Adverse Childhood Experiences, Symptom Severity, Negative Thinking, Comorbidity, and Treatment Response in Youth with Obsessive-Compulsive Disorder

Mariana Vazquez1, Amanda Palo1, McKenzie Schuyler2, Brent J. Small3, Joseph F. McGuire4, Sabine Wilhelm2,5, Wayne K. Goodman1, Daniel Geller2,5, Eric A. Storch1
1Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, USA
2Massachusetts General Hospital, Boston, USA
3University of South Florida, Tampa, USA
4Department of Psychiatry and Behavioral Science; Johns Hopkins University School of Medicine; Baltimore USA
5Harvard Medical School, Boston, USA;

Tóm tắt

Although youth and adults with obsessive-compulsive disorder (OCD) endorse elevated incidence of exposure to traumatic life events during childhood, the existing literature on adverse childhood experiences (ACEs) and OCD is mixed and studies focusing on pediatric OCD are limited. The present study examines the relationship between ACEs and OCD onset, symptom severity, negative cognitive patterns, comorbidity, and cognitive-behavioral therapy (CBT) response in 142 children and adolescents with OCD. ACEs were ascertained from parent reports. Most parents reported child exposure to ACEs. Out of the parents who reported ACEs, 50% reported ACE exposure prior to OCD diagnosis and 50% reported ACE exposure after OCD diagnosis. No significant associations between ACEs and comorbidity or CBT response were found, suggesting that CBT for pediatric OCD is effective regardless of ACE exposure. Family financial problems were associated with increased obsessive-compulsive symptom severity and negative thinking. Implications for research and practice are discussed.

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