A Double Fail-Safe Approach to Prevent Tumorigenesis and Select Pancreatic β Cells from Human Embryonic Stem Cells

Elsevier BV - Tập 12 - Trang 611-623 - 2019
Mirza Muhammad Fahd Qadir1,2, Silvia Álvarez-Cubela1, Kinsley Belle1, Tamar Sapir1, Fanuel Messaggio1, Kevin B. Johnson1, Oliver Umland1, Darrell Hardin1, Dagmar Klein1, Ingrid Pérez-Álvarez3, Fatima Sadiq4, Oscar Alcázar1, Luca A. Inverardi1,5,6, Camillo Ricordi1,7,8, Peter Buchwald1,9, Christopher A. Fraker1,8, Ricardo L. Pastori1,6, Juan Domínguez-Bendala1,2,7
1Diabetes Research Institute, University of Miami, Miller School of Medicine, Miami, FL, 33136, USA
2Department of Cell Biology, University of Miami Miller School of Medicine, Miami, FL, USA
3University of California Irvine Medical Center, Orange, CA 92868, USA
4Center for Specialized Surgery, Florida Hospital, Orlando, FL 32804, USA
5Department of Microbiology & Immunology, University of Miami Miller School of Medicine, Miami, FL, USA
6Department of Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Miami Miller School of Medicine, Miami, FL, USA
7Department of Surgery, University of Miami Miller School of Medicine, Miami, FL, USA
8Department of Biomedical Engineering, University of Miami Miller School of Medicine, Miami, FL, USA
9Department of Molecular and Cellular Pharmacology, University of Miami, Miller School of Medicine, Miami, FL, USA

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