Cirrhosis and end-stage chronic liver disease: The changing scenes on etiopathogenesis

Current Medicine Research and Practice - Tập 4 - Trang 62-77 - 2014
Nabeen C. Nayak1
1Department of Pathology, Sir Ganga Ram Hospital, New Delhi 110060, India

Tài liệu tham khảo

Bell, 2008, The epidemiology of newly diagnosed chronic liver disease in gastroenterology practices in the United States: results from population-based surveillance, Am J Gastroenterol, 103, 2727, 10.1111/j.1572-0241.2008.02071.x Blachier, 2013, The burden of liver disease in Europe: a review of available epidemiological data, J Hepatol, 58, 593, 10.1016/j.jhep.2012.12.005 El-Serag, 2012, Epidemiology of viral hepatitis and hepatocellular carcinoma, Gastroenterology, 142, 1264, 10.1053/j.gastro.2011.12.061 Karoney, 2013, Hepatitis C virus (HCV) infection in Africa: a review, Pan Afr Med J, 14, 44 Lee, 2012, Type and cause of liver disease in Korea: single-center experience, 2005–2010, Clin Mol Hepatol, 18, 309, 10.3350/cmh.2012.18.3.309 Nayak, 2012, Etiologic types of end-stage chronic liver disease in adults: analysis of prevalence and their temporal changes from a study on native liver explants, Eur J Gastroenterol Hepatol, 24, 2199, 10.1097/MEG.0b013e32835643f1 Song, 2013, Etiological features of cirrhosis inpatients in Beijing, China, Chin Med J (Engl), 126, 2430 Strickland, 2006, Liver disease in Egypt: hepatitis C superseded schistosomiasis as a result of iatrogenic and biological factors, Hepatology, 43, 915, 10.1002/hep.21173 Suzuki, 2013, Survey of non-B, non-C liver cirrhosis in Japan, Hepatol Res, 43, 1020 Ward, 2013, The epidemiology of chronic hepatitis C and one-time hepatitis C virus testing of persons born during 1945 to 1965 in the United States, Clin Liver Dis, 17, 1, 10.1016/j.cld.2012.09.011 Schuppan, 1999, Herbal products for liver diseases: a therapeutic challenge for the new millennium, Hepatology, 30, 1099, 10.1002/hep.510300437 Taha, 2010, Liver disease and the Niles: an association since Millenia – Editorial, Nile Liv J, 1, 1 Wang, 2000, Treatment of chronic liver diseases with traditional Chinese medicine, J Gastroenterol Hepatol, 15, E67, 10.1046/j.1440-1746.2000.02100.x Westreich, 1990, Liver disease in the Talmud, J Clin Gastroenterol, 12, 57, 10.1097/00004836-199002000-00015 Duffin, 1987, Why does cirrhosis belong to Laennec?, CMAJ, 137, 393 Laennec, 1819, vol. 1, 368 Roguin, 2006, Rene Theophile Hyacinthe Laennec (1781–1826): the man behind the stethoscope, Clin Med Res, 4, 230, 10.3121/cmr.4.3.230 Nayak, 2003, Hepatocellular carcinoma – a model of human cancer: clinico-pathological features, etiology and pathogenesis, Indian J Pathol Microbiol, 46, 1 Nayak, 1979, Nutritional liver disease, 221 Gall, 1960, Posthepatitic, postnecrotic, and nutritional cirrhosis: a pathologic analysis, Am J Pathol, 36, 241 Popper, 1954, Nutritional hepatic injury, AMA Arch Intern Med, 94, 785, 10.1001/archinte.1954.00250050099010 Lieber, 1965, Effects of prolonged ethanol intake: production of fatty liver despite adequate diets, J Clin Invest, 44, 1009, 10.1172/JCI105200 Lieber, 1969, Alcoholic fatty liver, N Engl J Med, 280, 705, 10.1056/NEJM196903272801306 Rubin, 1970, Effects of ethanol on the biogenesis of mitochondrial membranes and associated mitochondrial functions, Lab Invest, 23, 620 Rubin, 1975, Relation of alcoholic liver injury to cirrhosis, Clin Gastroenterol, 4, 247, 10.1016/S0300-5089(21)00112-7 Bhuyan, 1972, Fibroplasia in experimental protein deficiency: a study of fibroblastic growth and of collagen formation and resorption in the rat, J Pathol, 108, 191, 10.1002/path.1711080304 Bhuyan, 1965, Effect of dietary protein on carbon tetrachloride-induced hepatic fibrogenesis in Albino rats, Lab Invest, 14, 184 Schaffner, 1970, Alcoholic hepatitis in the spectrum of ethanol-induced liver injury, Scand J Gastroenterol Suppl, 7, 69 Anthony, 1978, The morphology of cirrhosis. Recommendations on definition, nomenclature, and classification by a working group sponsored by the World Health Organization, J Clin Pathol, 31, 395, 10.1136/jcp.31.5.395 Anthony, 1977, The morphology of cirrhosis: definition, nomenclature, and classification, Bull World Health Organ, 55, 521 Hall, 1994, Pathological spectrum of alcoholic liver disease, Alcohol Alcohol Suppl, 2, 303 Crabb, 1999, Pathogenesis of alcoholic liver disease: newer mechanisms of injury, Keio J Med, 48, 184, 10.2302/kjm.48.184 Teli, 1995, Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver, Lancet, 346, 987, 10.1016/S0140-6736(95)91685-7 Bellentani, 1997, Drinking habits as cofactors of risk for alcohol induced liver damage. The Dionysos Study Group, Gut, 41, 845, 10.1136/gut.41.6.845 Mandayam, 2004, Epidemiology of alcoholic liver disease, Semin Liver Dis, 24, 217, 10.1055/s-2004-832936 Menon, 2001, Pathogenesis, diagnosis, and treatment of alcoholic liver disease, Mayo Clin Proc, 76, 1021, 10.4065/76.10.1021 Day, 2000, Who gets alcoholic liver disease: nature or nurture?, J R Coll Physicians Lond, 34, 557 Day, 1992, Genetic predisposition to alcoholic liver disease, Gut, 33, 1444, 10.1136/gut.33.11.1444 Yoon, 2006 Cochrane, 2003, Alcohol use in China, Alcohol Alcohol, 38, 537, 10.1093/alcalc/agg111 Michitaka, 2010, Etiology of liver cirrhosis in Japan: a nationwide survey, J Gastroenterol, 45, 86, 10.1007/s00535-009-0128-5 Alter, 1966, Further studies on a “new” human isoprecipitin system (Australia antigen), Blood, 27, 297, 10.1182/blood.V27.3.297.297 Beasley, 1988, Hepatitis B virus. The major etiology of hepatocellular carcinoma, Cancer, 61, 1942, 10.1002/1097-0142(19880515)61:10<1942::AID-CNCR2820611003>3.0.CO;2-J Beasley, 1981, Hepatocellular carcinoma and hepatitis B virus. A prospective study of 22 707 men in Taiwan, Lancet, 2, 1129, 10.1016/S0140-6736(81)90585-7 Blumberg, 1981, Hepatitis B virus and the prevention of primary hepatocellular carcinoma, N Engl J Med, 304, 782, 10.1056/NEJM198103263041312 Nayak, 1987, Dynamics and impact of perinatal transmission of hepatitis B virus in North India, J Med Virol, 21, 137, 10.1002/jmv.1890210205 Das, 1980, Establishment of a human hepatocellular carcinoma cell line releasing hepatitis B virus surface antigen, Br J Exp Pathol, 61, 648 Nayak, 1977, Association of human hepatocellular carcinoma and cirrhosis with hepatitis B virus surface and core antigens in the liver, Int J Cancer, 20, 643, 10.1002/ijc.2910200502 Nayak, 1975, Localization of hepatitis B surface antigen in conventional paraffin sections of the liver. Comparison of immunofluorescence, immunoperoxidase, and orcein staining methods with regard to their specificity and reliability as antigen marker, Am J Pathol, 81, 479 Nayak, 1979, Demonstration of hepatitis B virus surface component in human hepatocellular cancer cells, Indian J Med Res, 69, 161 Thung, 1981, Animal model of human disease. Chimpanzee carriers of hepatitis B virus. Chimpanzee hepatitis B carriers, Am J Pathol, 105, 328 Popper, 1981, Woodchuck hepatitis and hepatocellular carcinoma: correlation of histologic with virologic observations, Hepatology, 1, 91, 10.1002/hep.1840010202 Maynard, 1990, Hepatitis B: global importance and need for control, Vaccine, 8 Nayak, 1983, Vaccine against hepatocellular carcinoma – prospects of a new era in cancer control, Indian J Med Res, 78, 1 World, 1983 Chang, 1997, Universal hepatitis B vaccination in Taiwan and the incidence of hepatocellular carcinoma in children. Taiwan Childhood Hepatoma Study Group, N Engl J Med, 336, 1855, 10.1056/NEJM199706263362602 Da Villa, 1998, Long-term epidemiological survey of hepatitis B virus infection in a hyperendemic area (Afragola, southern Italy): results of a pilot vaccination project, Res Virol, 149, 263, 10.1016/S0923-2516(99)89004-9 Sathar, 1996, The changing scenario of hepatitis B and hepatitis C virus associated chronic liver disease – a histopathological analysis, Med Princ Pract, 5, 76, 10.1159/000157385 Feinstone, 1973, Hepatitis A: detection by immune electron microscopy of a virus like antigen associated with acute illness, Science, 182, 1026, 10.1126/science.182.4116.1026 Feinstone, 1975, Transfusion-associated hepatitis not due to viral hepatitis type A or B, N Engl J Med, 292, 767, 10.1056/NEJM197504102921502 Purcell, 1976, Non-A, non-B hepatitis, Yale J Biol Med, 49, 243 Panda, 1989, Etiologic spectrum of acute sporadic viral hepatitis in children in India, Trop Gastroenterol, 10, 106 Panda, 1989, Enterically transmitted non-A, non-B hepatitis: recovery of virus-like particles from an epidemic in south Delhi and transmission studies in rhesus monkeys, Hepatology, 10, 466, 10.1002/hep.1840100411 Choo, 1989, Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome, Science, 244, 359, 10.1126/science.2523562 Houghton, 2009, The long and winding road leading to the identification of the hepatitis C virus, J Hepatol, 51, 939, 10.1016/j.jhep.2009.08.004 Liang, 2000, Pathogenesis, natural history, treatment, and prevention of hepatitis C, Ann Intern Med, 132, 296, 10.7326/0003-4819-132-4-200002150-00008 Bartenschlager, 2000, Replication of hepatitis C virus, J Gen Virol, 81, 1631, 10.1099/0022-1317-81-7-1631 Ganem, 2004, Hepatitis B virus infection – natural history and clinical consequences, N Engl J Med, 350, 1118, 10.1056/NEJMra031087 Chen, 2000, Epidemiology of hepatitis B virus infection in the Asia-Pacific region, J Gastroenterol Hepatol, 15, E3, 10.1046/j.1440-1746.2000.02124.x 2000 Chen, 2006, The natural history of hepatitis C virus (HCV) infection, Int J Med Sci, 3, 47, 10.7150/ijms.3.47 Mitra, 1999, Hepatitis C-related hepatocellular carcinoma: prevalence around the world, factors interacting, and role of genotypes, Epidemiol Rev, 21, 180, 10.1093/oxfordjournals.epirev.a017995 Sagnelli, 2005, The importance of HCV on the burden of chronic liver disease in Italy: a multicenter prevalence study of 9,997 cases, J Med Virol, 75, 522, 10.1002/jmv.20313 Sanghvi, 2013, Neglected tropical diseases as a cause of chronic liver disease: the case of Schistosomiasis and Hepatitis C co-infections in Egypt, Liver Int, 33, 165, 10.1111/liv.12052 Sama, 1971, Noncirrhotic portal fibrosis, Am J Med, 51, 160, 10.1016/0002-9343(71)90234-8 Boyer, 1967, Idiopathic portal hypertension. Comparison with the portal hypertension of cirrhosis and extrahepatic portal vein obstruction, Ann Intern Med, 66, 41, 10.7326/0003-4819-66-1-41 Mikkelsen, 1965, Extra- and intrahepatic portal hypertension without cirrhosis (hepatoportal sclerosis), Ann Surg, 162, 602, 10.1097/00000658-196510000-00006 Krasinskas, 2005, Liver transplantation for severe intrahepatic noncirrhotic portal hypertension, Liver Transpl, 11, 627, 10.1002/lt.20431 Nayak, 1969, Obliterative portal venopathy of the liver. Associated with so-called idiopathic portal hypertension or tropical splenomegaly, Arch Pathol, 87, 359 Okuda, 1982, Liver pathology of idiopathic portal hypertension. Comparison with non-cirrhotic portal fibrosis of India. The Japan idiopathic portal hypertension study, Liver, 2, 176, 10.1111/j.1600-0676.1982.tb00195.x Sarin, 2002, Non-cirrhotic portal fibrosis: current concepts and management, J Gastroenterol Hepatol, 17, 526, 10.1046/j.1440-1746.2002.02764.x Ludwig, 1980, Nonalcoholic steatohepatitis: Mayo clinic experiences with a hitherto unnamed disease, Mayo Clin Proc, 55, 434 Powell, 1990, The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years, Hepatology, 11, 74, 10.1002/hep.1840110114 Brunt, 1999, Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions, Am J Gastroenterol, 94, 2467, 10.1111/j.1572-0241.1999.01377.x Matteoni, 1999, Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity, Gastroenterology, 116, 1413, 10.1016/S0016-5085(99)70506-8 Corrao, 1997, Are the recent trends in liver cirrhosis mortality affected by the changes in alcohol consumption? Analysis of latency period in European countries, J Stud Alcohol, 58, 486, 10.15288/jsa.1997.58.486 Goncalves, 2013, Etiology of liver cirrhosis in Brazil: chronic alcoholism and hepatitis viruses in liver cirrhosis diagnosed in the state of Espirito Santo, Clinics (Sao Paulo), 68, 291, 10.6061/clinics/2013(03)OA02 Lu, 2004, Risk factors for alcoholic liver disease in China, World J Gastroenterol, 10, 2423, 10.3748/wjg.v10.i16.2423 Mendez-Sanchez, 2005, Trends in liver disease prevalence in Mexico from 2005 to 2050 through mortality data, Ann Hepatol, 4, 52, 10.1016/S1665-2681(19)32086-1 Afroudakis, 2000, Alcoholic liver disease – an overview, Ann Gastroenterol, 13, 290 O'Shea, 2010, Alcoholic liver disease, Am J Gastroenterol, 105, 14, 10.1038/ajg.2009.593 Becker, 2002, Lower risk for alcohol-induced cirrhosis in wine drinkers, Hepatology, 35, 868, 10.1053/jhep.2002.32101 Lefkowitch, 2005, Morphology of alcoholic liver disease, Clin Liver Dis, 9, 37, 10.1016/j.cld.2004.11.001 Brunt, 2005, Nonalcoholic steatohepatitis: pathologic features and differential diagnosis, Semin Diagn Pathol, 22, 330, 10.1053/j.semdp.2006.04.002 Hubscher, 2006, Histological assessment of non-alcoholic fatty liver disease, Histopathology, 49, 450, 10.1111/j.1365-2559.2006.02416.x Vasdev, 2007, Spectrum of histological features in non-alcoholic fatty liver disease, Natl Med J India, 20, 282 Ayata, 2002, Cryptogenic cirrhosis: clinicopathologic findings at and after liver transplantation, Hum Pathol, 33, 1098, 10.1053/hupa.2002.129419 Nayak, 2010, End-stage nonalcoholic fatty liver disease: evaluation of pathomorphologic features and relationship to cryptogenic cirrhosis from study of explant livers in a living donor liver transplant program, Hum Pathol, 41, 425, 10.1016/j.humpath.2009.06.021 Niemela, 2007, Biomarkers in alcoholism, Clin Chim Acta, 377, 39, 10.1016/j.cca.2006.08.035 Nyblom, 2004, High AST/ALT ratio may indicate advanced alcoholic liver disease rather than heavy drinking, Alcohol Alcohol, 39, 336, 10.1093/alcalc/agh074 Levitsky, 2004, Diagnosis and therapy of alcoholic liver disease, Semin Liver Dis, 24, 233, 10.1055/s-2004-832937 Grant, 1997, Barriers to alcoholism treatment: reasons for not seeking treatment in a general population sample, J Stud Alcohol, 58, 365, 10.15288/jsa.1997.58.365 Umbricht-Schneiter, 1991, Alcohol abuse: comparison of two methods for assessing its prevalence and associated morbidity in hospitalized patients, Am J Med, 91, 110, 10.1016/0002-9343(91)90002-F Mann, 2003, The epidemiology of alcoholic liver disease, Alcohol Res Health, 27, 209 Singal, 2013, Recent trends in the epidemiology of alcoholic liver disease, Clin Liver Dis, 2, 53, 10.1002/cld.168 Younossi, 2011, Changes in the prevalence of the most common causes of chronic liver diseases in the United States from 1988 to 2008, Clin Gastroenterol Hepatol, 9, 524, 10.1016/j.cgh.2011.03.020 Carrion, 2011, Chronic liver disease in the Hispanic population of the United States, Clin Gastroenterol Hepatol, 9, 834, 10.1016/j.cgh.2011.04.027 Jepsen, 2008, Alcoholic cirrhosis in Denmark – population-based incidence, prevalence, and hospitalization rates between 1988 and 2005: a descriptive cohort study, BMC Gastroenterol, 8, 3, 10.1186/1471-230X-8-3 Wiegand, 2010, The etiology, diagnosis and prevention of liver cirrhosis: part 1 of a series on liver cirrhosis, Dtsch Arztebl Int, 110, 85 Williams, 2006, Global challenges in liver disease, Hepatology, 44, 521, 10.1002/hep.21347 Nayak, 2011, End stage chronic liver disease – Yesterday, Today and Tomorrow, 59 Grewal, 2012, Liver cancer and alcohol, Clin Liver Dis, 16, 839, 10.1016/j.cld.2012.08.011 El-Serag, 2004, Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma, Gastroenterology, 126, 460, 10.1053/j.gastro.2003.10.065 Marrero, 2002, NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States, Hepatology, 36, 1349, 10.1053/jhep.2002.36939 Morgan, 2004, Alcohol and hepatocellular carcinoma, Gastroenterology, 127, S87, 10.1053/j.gastro.2004.09.020 Lavanchy, 2004, Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures, J Viral Hepat, 11, 97, 10.1046/j.1365-2893.2003.00487.x Mittal, 2013, Epidemiology of hepatocellular carcinoma: consider the population, J Clin Gastroenterol, 47, S2, 10.1097/MCG.0b013e3182872f29 Pungpapong, 2007, Natural history of hepatitis B virus infection: an update for clinicians, Mayo Clin Proc, 82, 967, 10.4065/82.8.967 Gao, 2005, Tight association of hepatocellular carcinoma with HBV infection in North China, Hepatobiliary Pancreat Dis Int, 4, 46 Mendy, 2010, Hepatitis B viral load and risk for liver cirrhosis and hepatocellular carcinoma in The Gambia, West Africa, J Viral Hepat, 17, 115, 10.1111/j.1365-2893.2009.01168.x Bojuwove, 1997, The burden of viral hepatitis in Africa, West Afr J Med, 16, 198 Raptis, 2003, Changing relative roles of hepatitis B and C viruses in the aetiology of hepatocellular carcinoma in Greece. Epidemiological and clinical observations, J Viral Hepat, 10, 450, 10.1046/j.1365-2893.2003.00442.x Roman, 2009, A low steady HBsAg seroprevalence is associated with a low incidence of HBV-related liver cirrhosis and hepatocellular carcinoma in Mexico: a systematic review, Hepatol Int, 3, 343, 10.1007/s12072-008-9115-9 Safary, 2000, Vaccination against hepatitis B: current challenges for Asian countries and future directions, J Gastroenterol Hepatol, 15, 396, 10.1046/j.1440-1746.2000.02002.x Romano, 2011, The worldwide impact of vaccination on the control and protection of viral hepatitis B, Dig Liver Dis, 43, S2, 10.1016/S1590-8658(10)60685-8 Lavanchy, 2012, Viral hepatitis: global goals for vaccination, J Clin Virol, 55, 296, 10.1016/j.jcv.2012.08.022 Nguyen, 2009, Hepatitis B-related hepatocellular carcinoma: epidemiological characteristics and disease burden, J Viral Hepat, 16, 453, 10.1111/j.1365-2893.2009.01117.x Shepard, 2006, Hepatitis B virus infection: epidemiology and vaccination, Epidemiol Rev, 28, 112, 10.1093/epirev/mxj009 Alter, 2007, Epidemiology of hepatitis C virus infection, World J Gastroenterol, 13, 2436, 10.3748/wjg.v13.i17.2436 Rustgi, 2007, The epidemiology of hepatitis C infection in the United States, J Gastroenterol, 42, 513, 10.1007/s00535-007-2064-6 Nayak, 1998, Chronic hepatitis – are we zeroing in on it now?, 126 Shepard, 2005, Global epidemiology of hepatitis C virus infection, Lancet Infect Dis, 5, 558, 10.1016/S1473-3099(05)70216-4 Perz, 2006, The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide, J Hepatol, 45, 529, 10.1016/j.jhep.2006.05.013 Cui, 2013, Update on epidemiology of hepatitis B and C in China, J Gastroenterol Hepatol, 28, 7, 10.1111/jgh.12220 Halliday, 2011, Vaccination for hepatitis C virus: closing in on an evasive target, Expert Rev Vaccines, 10, 659, 10.1586/erv.11.55 Angulo, 2002, Non-alcoholic fatty liver disease, J Gastroenterol Hepatol, 17, S186, 10.1046/j.1440-1746.17.s1.10.x Clark, 2003, Nonalcoholic fatty liver disease: an underrecognized cause of cryptogenic cirrhosis, JAMA, 289, 3000, 10.1001/jama.289.22.3000 Fan, 2009, Epidemiology of non-alcoholic fatty liver disease in China, J Hepatol, 50, 204, 10.1016/j.jhep.2008.10.010 Raszeja-Wyszomirska, 2008, Non-alcoholic fatty liver disease – new view, Pol Merkur Lekarski, 24, 568 Vuppalanchi, 2009, Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: selected practical issues in their evaluation and management, Hepatology, 49, 306, 10.1002/hep.22603 Rafiq, 2009, Long-term follow-up of patients with nonalcoholic fatty liver, Clin Gastroenterol Hepatol, 7, 234, 10.1016/j.cgh.2008.11.005 Ratziu, 2005, Sampling variability of liver biopsy in nonalcoholic fatty liver disease, Gastroenterology, 128, 1898, 10.1053/j.gastro.2005.03.084 Brunt, 2005, Pathology of nonalcoholic steatohepatitis, Hepatol Res, 33, 68, 10.1016/j.hepres.2005.09.006 Das, 2010, Nonobese population in a developing country has a high prevalence of nonalcoholic fatty liver and significant liver disease, Hepatology, 51, 1593, 10.1002/hep.23567 Jain, 2012, Hepatocellular carcinoma in nonalcoholic fatty liver cirrhosis and alcoholic cirrhosis: risk factor analysis in liver transplant recipients, Eur J Gastroenterol Hepatol, 24, 840, 10.1097/MEG.0b013e3283534b40 Malik, 2009, Liver transplantation in patients with nonalcoholic steatohepatitis-related hepatocellular carcinoma, Clin Gastroenterol Hepatol, 7, 800, 10.1016/j.cgh.2009.02.025 Michelotti, 2013, NAFLD, NASH and liver cancer, Nat Rev Gastroenterol Hepatol, 10.1038/nrgastro.2013.183 Sanyal, 2005, Review article: non-alcoholic fatty liver disease and hepatitis C – risk factors and clinical implications, Aliment Pharmacol Ther, 22, 48, 10.1111/j.1365-2036.2005.02596.x Stroffolini, 2010, Interaction of alcohol intake and cofactors on the risk of cirrhosis, Liver Int, 30, 867, 10.1111/j.1478-3231.2010.02261.x Nayak, 2011, Non-cirrhotic portal fibrosis: one disease with many names? An analysis from morphological study of native explant livers with end stage chronic liver disease, J Clin Pathol, 64, 592, 10.1136/jcp.2010.087395 Saigal, 2011, Non-cirrhotic portal fibrosis related end stage liver disease in adults: evaluation from a study on living donor liver transplant recipients, Hepatol Int, 5, 882, 10.1007/s12072-010-9246-7 Boonstra, 2012, Epidemiology of primary sclerosing cholangitis and primary biliary cirrhosis: a systematic review, J Hepatol, 56, 1181, 10.1016/j.jhep.2011.10.025 Isabel Fiel, 2007, Liver failure and need for liver transplantation in patients with advanced hepatoportal sclerosis, Am J Surg Pathol, 31, 607, 10.1097/01.pas.0000213425.76621.f1 Nayak, 2013, Indian childhood cirrhosis (ICC) & ICC-like diseases: the changing scenario of facts versus notions, Indian J Med Res, 137, 1029 Bozic, 2013, Pediatric nonalcoholic fatty liver disease, Nutr Clin Pract, 28, 448, 10.1177/0884533613489153 Tandon, 2013, Prevalence of metabolic syndrome among urban Indian adolescents and its relation with insulin resistance (HOMA-IR), J Pediat Endocrinol Metabol, 10.1515/jpem-2013-0020 Welsh, 2013, Increasing prevalence of nonalcoholic fatty liver disease among United States adolescents, 1988–1994 to 2007–2010, J Pediatr, 162, 496, 10.1016/j.jpeds.2012.08.043 Kew, 2013, Hepatitis viruses (other than hepatitis B and C viruses) as causes of hepatocellular carcinoma: an update, J Viral Hepat, 20, 149, 10.1111/jvh.12043 Patrick, 1952 Orman, 2013, Alcoholic liver disease: pathogenesis, management, and novel targets for therapy, J Gastroenterol Hepatol, 28, 77, 10.1111/jgh.12030 Wong, 2013, Nonalcoholic fatty liver disease in Asia: a story of growth, J Gastroenterol Hepatol, 28, 18, 10.1111/jgh.12011 Hsu, 2013, Non-alcoholic fatty liver disease: an emerging liver disease in Taiwan, J Formos Med Assoc, 111, 527, 10.1016/j.jfma.2012.07.002 McCullough, 2011, Epidemiology of the metabolic syndrome in the USA, J Dig Dis, 12, 333, 10.1111/j.1751-2980.2010.00469.x