Solidagenone acts on promastigotes of L. amazonensis by inducing apoptosis-like processes on intracellular amastigotes by IL-12p70/ROS/NO pathway activation

Phytomedicine - Tập 85 - Trang 153536 - 2021
Bruna Taciane da Silva Bortoleti1,2, Manoela Daiele Gonçalves3, Fernanda Tomiotto-Pellissier1,2, Virginia Marcia Contato2, Taylon Felipe Silva2, Ricardo Luís Nascimento de Matos3, Mariana Barbosa Detoni2, Ana Carolina Jacob Rodrigues2, Amanda Cristina Carloto2, Danielle Bidóia Lazarin2, Nilton Syogo Arakawa3, Idessania Nazareth Costa2, Ivete Conchon-Costa2, Milena Menegazzo Miranda-Sapla2, Pryscilla Fanini Wowk4, Wander Rogério Pavanelli2
1Biosciences and Biotechnology Postgraduate Program, Carlos Chagas Institute (ICC/Fiocruz-PR), Curitiba, Paraná, Brazil
2State University of Londrina (UEL/PR), Laboratory of Immunoparasitology, Londrina, Paraná, Brazil
3State University of Londrina (UEL/PR), Laboratory of Biotransformation and Phytochemistry, Londrina, Paraná, Brazil
4Carlos Chagas Institute (ICC/Fiocruz-PR), Laboratory of Molecular Virology, Curitiba, Paraná, Brazil

Tài liệu tham khảo

Aloui, 2016, Asteraceae Artemisia campestris and Artemisia herba-alba essential oils trigger apoptosis and cell cycle arrest in Leishmania infantum promastigotes, Evid. based Complement. Altern. Med., 2016, 10.1155/2016/9147096 Antwi, 2019, In vitro activity and mode of action of phenolic compounds on Leishmania donovani, PLoS Negl. Trop. Dis., 13, 1, 10.1371/journal.pntd.0007206 Araújo, 2019, Flavonoids induce cell death in: Leishmania amazonensis: in vitro characterization by flow cytometry and raman spectroscopy, Analyst, 144, 5232, 10.1039/C9AN00948E Bortoleti, 2018, Grandiflorenic acid promotes death of promastigotes via apoptosis-like mechanism and affects amastigotes by increasing total iron bound capacity, Phytomedicine, 46, 11, 10.1016/j.phymed.2018.06.010 Caldas, 2019, Antileishmanial activity and ultrastructural changes of sesquiterpene lactones isolated from Calea pinnatifida (Asteraceae), Bioorg. Chem., 83, 348, 10.1016/j.bioorg.2018.10.059 Cheng, 2012, AdmetSAR: a comprehensive source and free tool for assessment of chemical ADMET properties, J. Chem. Inf. Model., 52, 3099, 10.1021/ci300367a Cuadrado, 2018, Semisynthesis and inhibitory effects of solidagenone derivatives on TLR-mediated inflammatory responses, Molecules, 23, 3197, 10.3390/molecules23123197 Dolai, 2014, Endoplasmic reticulum stress responses in Leishmania, Mol. Biochem. Parasitol., 197, 1, 10.1016/j.molbiopara.2014.09.002 Duarte, 2005, Anti-Candida activity of brazilian medicinal plants, J. Ethnopharmacol., 97, 305, 10.1016/j.jep.2004.11.016 Fang, 2004, Antimicrobial reactive oxygen and nitrogen species: concepts and controversies, Nat. Rev. Microbiol., 2, 820, 10.1038/nrmicro1004 Gastaldi, 2018, Nutraceutical properties of herbal infusions from six native plants of argentine patagonia, Plant Foods Hum. Nutr., 73, 180, 10.1007/s11130-018-0680-3 Lipinski, 2004, Lead- and drug-like compounds: the rule-of-five revolution, Drug Discov. Today Technol., 1, 337, 10.1016/j.ddtec.2004.11.007 Liu, 2012, The early interaction of Leishmania with macrophages and dendritic cells and its influence on the host immune response, Front. Cell. Infect. Microbiol., 2, 83, 10.3389/fcimb.2012.00083 Malpezzi-Marinho, 2019, Effects of hydroalcoholic extract of Solidago chilensis Meyen on nociception and hypernociception in rodents, BMC Complement. Altern. Med., 19, 72, 10.1186/s12906-019-2478-8 Matos, R.L.N., 2019. Perfil fitoquímico e Solidagenona isolada de raízes de Solidago chilensis Meyen: avaliação dos efeitos em modelos biológicos explantes de pele de suíno. Dissertation, Pharmaceutical Sciences, State University of Londrina (UEL/PR). Menna-Barreto, 2019, Cell death pathways in pathogenic trypanosomatids: lessons of (over)kill, Cell Death Dis, 10, 93, 10.1038/s41419-019-1370-2 Mushtaq, 2018, Natural products as reservoirs of novel therapeutic agents, Excli J, 17, 420 Pellegrini, 2017, Chemical composition, antimicrobial activity, and mode of action of essential oils against Paenibacillus larvae, etiological agent of american foulbrood on Apis mellifera, Chem. Biodivers., 14, 10.1002/cbdv.201600382 Rodrigues, 2015, Natural products: insights into leishmaniasis inflammatory response, Mediators Inflamm, 2015, 1, 10.1155/2015/835910 Rodríguez, 2002, Gastroprotective activity of solidagenone on experimentally-induced gastric lesions in rats, J. Pharm. Pharmacol., 54, 399, 10.1211/0022357021778466 Rodríguez, 2005, Gastroprotective and ulcer-healing effect of new solidagenone derivatives in human cell cultures, Life Sci, 77, 2193, 10.1016/j.lfs.2005.04.007 Rossi, 2018, How to master the host immune system? Leishmania parasites have the solutions!, Int. Immunol., 30, 103, 10.1093/intimm/dxx075 Schmeda-Hirschmann, 2004, Biotransformation of solidagenone by Alternaria alternata, Aspergillus niger and Curvularia lunata cultures, World J Microb and Biot, 20, 93, 10.1023/B:WIBI.0000013317.60257.33 Sen, 2007, Artemisinin triggers induction of cell-cycle arrest and apoptosis in Leishmania donovani promastigotes, J. Med. Microbiol., 56, 1213, 10.1099/jmm.0.47364-0 Singh, 2016, Current challenges in treatment options for visceral leishmaniasis in India: a public health perspective, Infect. Dis. poverty, 5, 19, 10.1186/s40249-016-0112-2 Smirlis, 2010, Targeting essential pathways in trypanosomatids gives insights into protozoan mechanisms of cell death, Parasit. Vectors, 3, 107, 10.1186/1756-3305-3-107 Soares, 2017, Sera from visceral leishmaniasis patients display oxidative activity and affect the TNF- α production by macrophages in vitro, Biomed Res. Int., 2017, 10.1155/2017/5861453 Tamura, 2009, Inhibitory effects of Solidago chilensis Meyen hydroalcoholic extract on acute inflammation, J. Ethnopharmacol., 122, 478, 10.1016/j.jep.2009.01.029 Tomiotto-Pellissier, 2018, Macrophage polarization in leishmaniasis: broadening horizons, Front. Immunol., 9, 2529, 10.3389/fimmu.2018.02529 Valverde, 2020, Solidagenone from Solidago chilensis Meyen inhibits skin inflammation in experimental models, Basic Clin. Pharmacol. Toxicol., 128, 91, 10.1111/bcpt.13479 van de Waterbeemd, 2003, ADMET in silico modelling: towards prediction paradise?, Nat. Rev. Drug Discov., 10.1038/nrd1032 Veber, 2002, Molecular properties that influence the oral bioavailability of drug candidates, J. Med. Chem., 45, 2615, 10.1021/jm020017n Volpato, 2015, Mitochondrial dysfunction induced by N-Butyl-1-(4-Dimethylamino)Phenyl-1,2,3,4-Tetrahydro-β-Carboline-3-carboxamide is required for cell death of Trypanosoma cruzi, PLoS ONE, 10, 10.1371/journal.pone.0130652 WHO; world health organization, 2019. Leishmaniasis. URL https://www.who.int/news-room/fact-sheets/detail/leishmaniasis (accessed 9.13.19). Yang, 2018, ADMETopt: a web server for ADMET optimization in drug design via scaffold hopping, J. Chem. Inf. Model., 58, 2051, 10.1021/acs.jcim.8b00532