Nucleotide sequence determination of point mutations at the mouse HPRT locus using in vitro amplification of HPRT mRNA sequences

Fuscoe, 1983, Deletion and amplification of the HGPRT locus in Chinese hamster cells, Mol. Cell. Biol., 3, 1086, 10.1128/MCB.3.6.1086 Fuscoe, 1986, Molecular analysis of X-ray-induced mutants at the HPRT locus in V79 Chinese hamster cells, Int. J. Radiat Biol., 49, 1011, 10.1080/09553008514553231 Geliebter, 1986, Mitotic recombination in germ cells generated two major histocompatibility complex mutant genes shown to be identical by RNA sequence analysis: Kbm9 and Kbm6, 83, 3371 Jones, 1985, A method to quantify spontaneous and invivo induced thioguanine-resistant mouse lymphocytes, Mutation Res., 147, 97, 10.1016/0165-1161(85)90022-6 Konecki, 1982, Hypoxanthine-guanine phosphoribosyltransferase genes of mouse and Chinese hamster: construction and sequence analysis of cDNA recombinants, Nucleic Acids Res., 10, 6753, 10.1093/nar/10.21.6763 Maniatis, 1982 Melton, 1982, In vitro translation of hypoxanthine/guanine phosphoribosyltransferase mRNA: Characterization of a mouse neuroblastoma cell line that has elevated levels of hypoxanthine/guanine phosphoribosyltransferase protein, 78, 6977 Melton, 1984, Structure, expression and mutation of the hypoxanthine phosphoribosyltransferase gene, 81, 2147 Messing, 1983, New M13 vectors for cloning, Methods Enzymol., 101, 20, 10.1016/0076-6879(83)01005-8 Saiki, 1985, Enzymatic amplication of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia, Science, 230, 1350, 10.1126/science.2999980 Saiki, 1986, Analysis of enzymatically amplified beta-globin and HLA-Dqalpha DNA with allele-specific oligonucleotide probes, Nature (London), 324, 163, 10.1038/324163a0 Sanger, 1977, DNA sequencing with chain-terminating inhibitors, 80, 726 Scharf, 1986, Direct cloning and sequence analysis of enzymatically amplified genomic sequences, Science, 233, 1076, 10.1126/science.3461561 Stankowski, 1986, Quantitative and molecular analyses of radiation-induced mutation in AS52 cells, Radiat. Res., 105, 37, 10.2307/3576723 Stankowski, 1986, Quantitatibe and molecular analyses of ethyl methne-sulfonate- and ICR 191-induced mutation in AS52 cells, Mutation Res., 160, 133, 10.1016/0027-5107(86)90037-0 Thacker, 1986, Molecular characterization of HPRT-deficient mutants induced by gamma-rays or alpha-particles showing that the majority have deletions of all or part of the hprt gene, Mutation Res., 160, 267, 10.1016/0027-5107(86)90137-5 Turner, 1986, In vivo somatic mutations in human lymphocytes frequently result from major gene alterations, Nature (London), 315, 343, 10.1038/315343a0 Verlaan-de Vries, 1987, A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides, Gene, 50, 313, 10.1016/0378-1119(86)90335-5 Vrieling, 1985, Mutations induced by X-ray at the HPRT locus in cultured Chinese hamster cells are mostly large deletion, Mutation Res., 144, 281, 10.1016/0165-7992(85)90065-X Vreiling, 1988, Molecular analysis of mutations by N-ethyl-N-nitrosourea at the HPRT locus in mouse lymphoma cells, Mutation Res., 198, 99, 10.1016/0027-5107(88)90045-0 Wilson, 1984, Human hypoxanthine-guanine phosphoribosyltransferase: structural alteration in a dysfunctional enzyme variant (HPRT Munich) isolated from a patient with gout, J. Biol. Chem., 259, 27, 10.1016/S0021-9258(17)43616-7 Wilson, 1983, Human hypoxanthine (guanine) phosphoribosyltransferase: An amino acid substitution in a mutant form of the enzyme isolated from a patient with gout, Proc. Natl. Acad. Sci. (U.S.A.), 80, 870, 10.1073/pnas.80.3.870 Wilson, 1983, Human hypoxanthine-guanine phosphoribosyltransferase: Molecular abnormality in a mutant form of the enzyme (HPRT Toronto), J. Biol. Chem., 258, 6458, 10.1016/S0021-9258(18)32432-3 Wrischnik, 1987, Length mutations in human mitochondrial DNA: direct sequencing of enzymatically amplified DNA, Nucleic Acids Res., 15, 529, 10.1093/nar/15.2.529 Yang, 1984, Molecular evidence for new mutation in the hprt locus in Lesch-Nyhan patients, Nature (London), 310, 412, 10.1038/310412a0