Nongenomic bronchodilating action elicited by dehydroepiandrosterone (DHEA) in a guinea pig asthma model

Julia Espinoza1, Luis M. Montaño2, Mercedes Perusquía1
1Universidad Nacional Autónoma de México, Instituto de Investigaciones Biomédicas, Departamento de Biología Celular y Fisiología, México, D.F. 04510, Mexico
2Universidad Nacional Autónoma de México, Facultad de Medicina, Departamento de Farmacología, México, D.F. 04510, Mexico

Tài liệu tham khảo

Becklake, 1999, Gender differences in airway behaviour over the human life span, Thorax, 54, 1119, 10.1136/thx.54.12.1119 Bonner, 1984, The epidemiology and natural history of asthma, Clinics in Chest Medicine, 5, 557, 10.1016/S0272-5231(21)00281-1 Kjellman, 2000, Asthma from childhood to adulthood: asthma severity, allergies, sensitization, living conditions, gender influence and social consequences, Respiratory Medicine, 94, 454, 10.1053/rmed.1999.0764 Ninan, 1992, Respiratory symptoms and atopy in Aberdeen schoolchildren: evidence from two surveys 25 years apart, BMJ, 304, 873, 10.1136/bmj.304.6831.873 Osman, 2003, Therapeutic implications of sex differences in asthma and atopy, Archives of Disease in Childhood, 88, 587, 10.1136/adc.88.7.587 Sears, 1997, Epidemiology of childhood asthma, Lancet, 350, 1015, 10.1016/S0140-6736(97)01468-2 The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee, 1998, Worldwide variations in the prevalence of asthma symptoms: the International Study of Asthma and Allergies in Childhood (ISAAC), The European Respiratory Journal, 12, 315, 10.1183/09031936.98.12020315 Townsend, 2012, Sex differences and sex steroids in lung health and disease, Endocrine Reviews, 33, 1, 10.1210/er.2010-0031 von, 1993, Prematurity as a risk factor for asthma in preadolescent children, Journal of Pediatrics, 123, 223, 10.1016/S0022-3476(05)81692-0 Zannolli, 1997, Does puberty interfere with asthma?, Medical Hypotheses, 48, 27, 10.1016/S0306-9877(97)90020-7 Almqvist, 2008, Impact of gender on asthma in childhood and adolescence: a GA2LEN review, Allergy, 63, 47 Chen, 2008, Gender difference, sex hormones, and immediate type hypersensitivity reactions, Allergy, 63, 1418, 10.1111/j.1398-9995.2008.01880.x De Marco, 2000, Differences in incidence of reported asthma related to age in men and women. A retrospective analysis of the data of the European Respiratory Health Survey, American Journal of Respiratory and Critical Care, 162, 68, 10.1164/ajrccm.162.1.9907008 Jeon, 2009, Lung function in Korean adolescent girls: in association with obesity and the menstrual cycle, Journal of Korean Medical Science, 24, 20, 10.3346/jkms.2009.24.1.20 Melgert, 2007, Are there reasons why adult asthma is more common in females?, Current Allergy and Asthma Reports, 7, 143, 10.1007/s11882-007-0012-4 Paoletti, 1995, Distribution of bronchial responsiveness in a general population: effect of sex, age, smoking, and level of pulmonary function, American Journal of Respiratory and Critical Care, 151, 1770, 10.1164/ajrccm.151.6.7767519 Postma, 2007, Gender differences in asthma development and progression, Gender Medicine, 4, S133, 10.1016/S1550-8579(07)80054-4 Canguven, 2011, Do low testosterone levels contribute to the pathogenesis of asthma?, Medical Hypotheses, 76, 585, 10.1016/j.mehy.2011.01.006 Rainey, 2002, Dissecting human adrenal androgen production, Trends in Endocrinology & Metabolism, 13, 234, 10.1016/S1043-2760(02)00609-4 Saltzman, 2006, Dehydroepiandrosterone therapy as female androgen replacement, Seminars in Reproductive Medicine, 24, 97, 10.1055/s-2006-939568 Traish, 2011, Dehydroepiandrosterone (DHEA) – a precursor steroid or an active hormone in human physiology, Journal of Sexual Medicine, 8, 2960, 10.1111/j.1743-6109.2011.02523.x Weinstein, 1996, Decreased adrenal sex steroid levels in the absence of glucocorticoid suppression in postmenopausal asthmatic women, Journal of Allergy and Clinical Immunology, 97, 1, 10.1016/S0091-6749(96)70276-2 Dunn, 1984, Dehydroepiandrosterone sulphate concentrations in asthmatic patients: pilot study, New Zealand Medical Journal, 97, 805 Feher, 1983, Adrenocortical function in bronchial asthma, Acta Medica Hungarica, 40, 125 Karalus, 1985, Adrenal function in acute severe asthma, New Zealand Medical Journal, 98, 843 Kasperska-Zajac, 2010, Asthma and dehydroepiandrosterone (DHEA): facts and hypotheses, Inflammation, 33, 320, 10.1007/s10753-010-9188-1 Yu, 1999, Attenuation of house dust mite Dermatophagoides farinae-induced airway allergic responses in mice by dehydroepiandrosterone is correlated with down-regulation of TH2 response, Clinical & Experimental Allergy, 29, 414, 10.1046/j.1365-2222.1999.00484.x Yu, 2002, Dehydroepiandrosterone attenuates allergic airway inflammation in Dermatophagoides farinae-sensitized mice, Journal of Microbiology, Immunology and Infection, 35, 199 Choi, 2008, Effects of dehydroepiandrosterone on Th2 cytokine production in peripheral blood mononuclear cells from asthmatics, Korean Journal of Internal Medicine, 23, 176, 10.3904/kjim.2008.23.4.176 Eusebio, 2011, The patents on glucocorticosteroids and selected new therapies for the management of asthma in children, Recent Patents on Inflammation & Allergy Drug Discovery, 5, 57, 10.2174/187221311794474865 Perusquia, 2005, Androgens induce relaxation of contractile activity in pregnant human myometrium at term: a nongenomic action on L-type calcium channels, Biology of Reproduction, 73, 214, 10.1095/biolreprod.104.036954 Perusquia, 2007, The modulatory role of androgens and progestins in the induction of vasorelaxation in human umbilical artery, Life Sciences, 81, 993, 10.1016/j.lfs.2007.07.024 Perusquía, 2003, Nongenomic action of dehydroepiandrosterone on vascular tone and uterine contractility, vol. 1, 143 Bramley, 1990, The role of the epithelium in modulating the responses of guinea-pig trachea induced by bradykinin in vitro, British Journal of Pharmacology, 99, 762, 10.1111/j.1476-5381.1990.tb13003.x Liu, 2002, Dehydroepiandrosterone activates endothelial cell nitric-oxide synthase by a specific plasma membrane receptor coupled to Galpha(i2,3), Journal of Biological Chemistry, 277, 21379, 10.1074/jbc.M200491200 Liu, 2004, Dehydroepiandrosterone stimulates nitric oxide release in vascular endothelial cells: evidence for a cell surface receptor, Steroids, 69, 279, 10.1016/j.steroids.2004.02.004 Bordallo, 2008, Modulatory role of endogenous androgens on airway smooth muscle tone in isolated guinea-pig and bovine trachea; involvement of beta2-adrenoceptors, the polyamine system and external calcium, European Journal of Pharmacology, 601, 154, 10.1016/j.ejphar.2008.10.039 Kouloumenta, 2006, Non-genomic effect of testosterone on airway smooth muscle, British Journal of Pharmacology, 149, 1083, 10.1038/sj.bjp.0706936 Townsend, 2010, Rapid effects of estrogen on intracellular Ca2+ regulation in human airway smooth muscle, American Journal of Physiology – Lung Cellular and Molecular Physiology, 298, L521, 10.1152/ajplung.00287.2009 Perusquia, 1997, Inhibitory effect of sex steroids on guinea-pig airway smooth muscle contractions, Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 118, 5, 10.1016/S0742-8413(97)00029-7 Cui, 2008, Effects of combined BCG and DHEA treatment in preventing the development of asthma, Immunological Investigations, 37, 191, 10.1080/08820130801967833 Wenzel, 2010, Nebulized dehydroepiandrosterone-3-sulfate improves asthma control in the moderate-to-severe asthma results of a 6-week, randomized, double-blind, placebo-controlled study, Allergy & Asthma Proceedings, 31, 461, 10.2500/aap.2010.31.3384 Williams, 2001, Disorders of the adrenal cortex, 2084 Perez-Zoghbi, 2009, Ion channel regulation of intracellular calcium and airway smooth muscle function, Pulmonary Pharmacology & Therapeutics, 22, 388, 10.1016/j.pupt.2008.09.006 Dai, 2006, Mechanism of ACh-induced asynchronous calcium waves and tonic contraction in porcine tracheal muscle bundle, American Journal of Physiology – Lung Cellular and Molecular Physiology, 290, L459, 10.1152/ajplung.00092.2005 Wang, 2012, Glucocorticoid decreases airway tone via a nongenomic pathway, Respiratory Physiology & Neurobiology, 183, 10, 10.1016/j.resp.2012.05.008 de Peretti, 1978, Pattern of plasma dehydroepiandrosterone sulfate levels in humans from birth to adulthood: evidence for testicular production, Journal of Clinical Endocrinology & Metabolism, 47, 572, 10.1210/jcem-47-3-572 Orentreich, 1992, Long-term longitudinal measurements of plasma dehydroepiandrosterone sulfate in normal men, Journal of Clinical Endocrinology & Metabolism, 75, 1002 Kroegel, 1997, Is there a place for intrinsic asthma as a distinct immunopathological entity?, European Respiratory Journal, 10, 513, 10.1183/09031936.97.10030513 Orentreich, 1984, Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood, Journal of Clinical Endocrinology & Metabolism, 59, 551, 10.1210/jcem-59-3-551 Regelson, 1988, Hormonal intervention: buffer hormones or state dependency. The role of dehydroepiandrosterone (DHEA), thyroid hormone, estrogen and hypophysectomy in aging, Annals of the New York Academy of Sciences, 521, 260, 10.1111/j.1749-6632.1988.tb35284.x Casson, 1993, Oral dehydroepiandrosterone in physiologic doses modulates immune function in postmenopausal women, American Journal of Obstetrics & Gynecology, 169, 1536, 10.1016/0002-9378(93)90431-H Daynes, 1990, Regulation of murine lymphokine production in vivo. II. Dehydroepiandrosterone is a natural enhancer of interleukin 2 synthesis by helper T cells, European Journal of Immunology, 20, 793, 10.1002/eji.1830200413 Koziol-White, 2012, DHEA-S inhibits human neutrophil and human airway smooth muscle migration, Biochimica et Biophysica Acta, 1822, 1638, 10.1016/j.bbadis.2012.06.012