Roles of Copper in Hepatocarcinogenesis via the Activation of Hypoxia-Inducible Factor-1α
Tóm tắt
Từ khóa
Tài liệu tham khảo
Semenza GL (1999) Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Biol 15:551–578
Wang GL, Jiang BH, Rue EA, Semenza GL (1995) Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci U S A 92:5510–5514
Dimova EY, Kietzmann T (2010) Hypoxia-inducible factors: post-translocational crosstalk of signaling pathways. Methods Mol Biol 647:215–236
Semenza GL (2002) HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol Med 8:S62–S67
Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, et al. (2000) Modulation of hypoxia-inducible factor-1 alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res 60:1541–1545
Box AH, Demetrick DJ (2004) Cell cycle kinase inhibitor expression and hypoxia-induced cell cycle arrest in human cancer cell lines. Carcinogenesis 25:2325–2335
Piret JP, Minet E, Cosse JP, Ninane N, Debacq C, Raes M, Michiels C (2005) Hypoxia-inducible factor-1-dependent overexpression of myeloid cell factor-1 protects hypoxic cells against tert-butyl hydroperoxide-induced apoptosis. J Biol Chem 280:9336–9344
Tanaka H, Yamamoto M, Hashimoto N, Miyakoshi M, Tamakawa S, et al. (2006) Hypoxia-independent overexpression of hypoxia-inducible factor 1α as an early change in mouse hepatocarcinogenesis. Cancer Res 66:11263–11270
Huang GW, Yang LY, Lu WQ (2005) Expression of hypoxia-inducible factor 1α and vascular endothelial growth factor in hepatocellular carcinoma: impact on neovascularization and survival. World J Gastroenterol 11:1705–1708
Yao DF, Jiang H, Yao M, Li YM, Gu WJ, et al. (2009) Quantitative analysis of hepatic hypoxia-inducible factor-1a and its abnormal gene expression during the formation of hepatocellular carcinoma. Hepatobiliary Pancreat Dis Int 8:407–413
Dai CX, Gao Q, Qiu SJ, Ju MJ, Cai MY, et al. (2009) Hypoxia-inducible factor-1 alpha, in association with inflammation, angiogenesis and MYC, is a critical prognostic factor in patients with HCC after surgery. BMC Cancer 9:418. doi: 10.1186/1471-2407-9-418
Gurusamy K (2007) Trace element concentration in primary liver cancers-a systemic review. Biol Trace Elem Res 118:191–206
Asare GA, Mossanda KS, Kew MC, Paterson AC, Kahler-Venter CP, Siziba K (2005) Hepatocellular carcinoma caused by iron overload: a possible mechanism of direct hepatocarcinogenicity. Toxicology 219:41–52
Ebara M, Fukuda H, Hatano R, Yoshikawa M, Sugiura N, et al. (2003) Metal contents in the liver of patients with chronic liver disease caused by hepatitis C virus. Oncology 65:323–330
Maeda T, Shimada M, Harimoto N, Tsujita E, Maehara S, et al. (2005) Role of tissue trace elements in liver cancers and non-cancerous liver parenchyma. Hepato-Gastroenterology 52:187–190
Okuno T, Shimamura Y, Mizuno M, Miyata S, Miyake T, et al. (1988) Trace elements in hepatoma tissues. Trace Elem Med 5:130–136
Martin F, Linden T, Katschinski DM, Oehme F, Flamme I, et al. (2005) Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation. Blood 105:4613–4619
Nardinocchi L, Pantisano V, Puca R, Porru M, Aiello A, et al. (2010) Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo. PLoS One 5:e15048. doi: 10.1371/journal.pone.0015048
Lifschits MD, Henkin RI (1971) Circadian variation in copper and zinc in man. J Appl Physiol 31:88–92
Ichida F, Tsuji T, Omata M, Ichida T, Inoue K, et al. (1996) New Inuyama classification: new criteria for histological assessment of chronic hepatitis. Int Hepatol Commun 6:112–119
Li S, Yao D, Wang L, Wu W, Qiu L, et al. (2011) Expression characteristics of hypoxia-inducible factor-1a and its clinical values in diagnosis and prognosis of hepatocellular carcinoma. Hepat Mon 11:821–828
Liang B, Zheng CS, Feng GS, Wu HP, Wang Y, et al. (2010) Correlation of hypoxia-inducible factor-1alpha with angiogenesis in liver tumors after transcatheter arterial embolization in an animal model. Cardiovasc Intervent Radiol 33:806–812
Miatto O, Casaril M, Gabrielli GB, Nicoli N, Bellisola G, et al. (1985) Diagnostic and prognostic value of serum copper and plasma fibrinogen in hepatic carcinoma. Cancer 55:774–778
Hatano R, Ebara M, Fukuda H, Yoshikawa M, Sugiura N, et al. (2000) Accumulation of copper in the liver and hepatic injury in chronic hepatitis C. J Gastroenterol Hepatol 15:786–791
Ebara M, Fukuda H, Hatano R, Saisho H, Nagato N, et al. (2000) Relationship between copper, zinc and metallothionein in hepatocellular carcinoma and its surrounding liver parenchyma. J Hepatol 32:415–422
Sugawara N, Sugawara C, Sato M, Takahashi H, Mori M (1992) Excessive accumulation of hepatic copper in LEC rats aged 80 days without hepatitis and 130 days with hepatitis. Pharmacol Toxicol 71:321–324
Himoto T, Yoneyama H, Deguchi A, Kurokohchi K, Inukai M, et al. (2010) Insulin resistance derived from zinc deficiency in non-diabetic patients with chronic hepatitis C. Exp Ther Med 1:707–711
Pramoolsinsap C, Promvant N, Komindr S, Lerdverasirikul P, Srianujata S (1994) Serum trace metals in chronic viral hepatitis and hepatocellular carcinoma in Thailand. J Gastroenterol 29:610–615
Poo JL, Rosas-Romero R, Montemayor AC, Isoard F, Uribe M (2003) Diagnostic value of copper/zinc ratio in hepatocellular carcinoma: a case control study. J Gastroenterol 38:45–51
Xie H, Kang YJ (2009) Role of copper in angiogenesis and its medical implications. Curr Med Chem 16:1304–1314
Matsumoto A, Hanayama R, Nakamura M, Suzuki K, Fujii J, Tatsumi H, Taniguchi N (1998) A high expression of heme oxygenase-1 in the liver of LEC rats at the stage of hepatoma: the possible implication of induction in uninvolved tissue. Free Radic Res 28:383–391
Feng W, Ye F, Xue W, Zhou Z, Kang J (2009) Copper regulation of hypoxia-inducible factor-1 activity. Mol Pharmacol 75:174–182
Kim I, Kim CH, Seo GH, Kim HS, Lee J, Kim DG, Ahn YS (2008) Inhibitory effect of hypoxic HIF-1 activation in astrocytes. Neuroreport 19:1063–1066
Wada H, Nagano H, Yamamoto H, Yang Y, Kondo M, et al. (2006) Expression pattern of angiogenic factors and prognosis after hepatic resection in hepatocellular carcinoma: importance of angiopoietin-2 and hypoxia-induced factor 1α. Liver Int 26:414–423
Nath B, Szabo G (2012) Hypoxia and hypoxia inducible factors: diverse roles in liver diseases. Hepatology 55:622–633
Osaki S, Da J, Frieden E (1966) The possible significance of the ferrous oxidase activity of ceruloplasmin in normal human serum. J Biol Chem 241:2746–2751