Resveratrol Isolated from Polygonum cuspidatum Root Prevents Tumor Growth and Metastasis to Lung and Tumor-Induced Neovascularization in Lewis Lung Carcinoma-Bearing Mice

Arichi, 1982, Effects of stilbene components of the roots of Polygonum cuspidatum Sieb et Zucc. on lipid metabolism, Chem. Pharm. Bull, 30, 1766, 10.1248/cpb.30.1766 Kimura, 1985, Effects of stilbenes on arachidonate metabolism in leukocytes, Biochim. Biophys. Acta, 834, 275, 10.1016/0005-2760(85)90167-5 Kimura, 1985, Effects of stilbene derivatives on arachidonate metabolism in leukocytes, Biochim. Biophys. Acta, 837, 209, 10.1016/0005-2760(85)90244-9 Kimura, 1995, Effects of stilbenes isolated from medicinal plants on arachidonate metabolism and degranulation in human polymorphonuclear leukocytes, J. Ethnopharmacol, 45, 131, 10.1016/0378-8741(94)01206-F Jang, 1997, Cancer chemopreventive activity of resveratrol, a natural product derived from grapes, Science (Washington, DC), 275, 218, 10.1126/science.275.5297.218 Ciolino, 1998, Resveratrol inhibits transcription of CYP1A1 in vitro by preventing activation of the aryl hydrocarbon receptor, Cancer Res, 58, 5707 Ragione, 1998, Resveratrol arrests the cell division cycle at S/G2 phase transition, Biochem. Biophys. Res. Commun, 250, 53, 10.1006/bbrc.1998.9263 Fontecave, 1998, Resveratrol, a remarkable inhibitor of ribonucleotide reductase, FEBS Lett, 421, 277, 10.1016/S0014-5793(97)01572-X Subbaranmaiah, 1998, Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cell, J. Biol. Chem, 273, 21875, 10.1074/jbc.273.34.21875 Sun, 1998, DNA polymerase and topoisomerase II inhibitors from Psoralea corylifolia, J. Nat. Prod, 61, 362, 10.1021/np970488q Clément, 1998, Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells, Blood, 92, 996, 10.1182/blood.V92.3.996 Carbò, 1999, Resveratrol, a natural product present in wine, decreases tumor growth in rat tumor model, Biochem. Biophys. Res. Commun, 254, 739, 10.1006/bbrc.1998.9916 Weiss, 1988, Interactions of cancer cells with the microvasculature during metastasis, FASEB J, 2, 12, 10.1096/fasebj.2.1.3275560 Blood, 1990, Tumor interactions with the vasculature: angiogensis and tumor metastasis, Biochim. Biophys. Acta, 1032, 89 Ferrara, 1995, Missing link in angiogenesis, Nature (Lond.), 376, 467, 10.1038/376467a0 Kerbel, 1997, A cancer therapy resistant to resistance, Nature (Lond.), 390, 335, 10.1038/36978 Kimura, 2000, Effects of naturally occurring stilbene glucosides from medicinal plants and wine, on tumor growth and lung metastasis in Lewis lung carcinoma-bearing mice, J. Pharm. Pharmacol, 52, 1287, 10.1211/0022357001777270 Kubo, 1981, Studies on the antifungal substance of crude drug (II). On the roots of Polygonum cuspidatum Sieb. et Zuccc. (Polygonaceae), Shoyakugaku Zasshi, 35, 58 Kimura, 1983, New constituents of roots of Polygonum cuspidatum, Planta Med, 48, 164, 10.1055/s-2007-969914 DeWys, 1972, Studies correlating the growth rate of a tumor and its metastases and providing evidence for tumor-related systemic growth-retarding factor, Cancer Res, 32, 374 Gorelik, 1978, Growth of local tumor exerts a specific inhibitory effect on progression of lung metastases, Int. J. Cancer, 21, 617, 10.1002/ijc.2910210512 Gorelik, 1980, Control of lung metastasis progression in mice: role of growth kinetics of 3 LL Lewis lung carcinoma and host immune reactivity, J. Natl. Cancer Inst, 65, 1257 O'Reilly, 1994, Angiostatin: a novel anigiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma, Cell, 79, 315, 10.1016/0092-8674(94)90200-3 Mu, 1995, Administration of recombinant interleukin 12 prevents outgrowth of tumor cells metastasizing spontaneously to lung and lymph nodes, Cancer Res, 55, 4404 Brunda, 1993, Antitumor and antimetastatic activity of interleukin-12 against murine tumors, J. Exp. Med, 178, 1223, 10.1084/jem.178.4.1223 Weiss, L. (1976) In: Fundamental Aspects of Metastasis (Weiss, L., ed.), pp. 51–70, North Holland, Amsterdam, The Netherlands. Liotta, 1986, Tumor invasion and metastases. Role of the extracellular matrix, Cancer Res, 46, 1 Honn, 1992, Adhesion molecules and tumor cell interaction with endothelium and subendothelial matrix, Cancer Metastasis Rev, 11, 353, 10.1007/BF01307187 Folkman, 1995, Angiogenesis in cancer, vascular, rheumatoid and other disease, Nat. Med, 1, 27, 10.1038/nm0195-27 Koch, 1995, Angiogenesis mediated by soluble forms of E-selectin and vascular cell adhesion molecule-1, Nature (Lond.), 376, 517, 10.1038/376517a0 Bischoff, 1997, Cell adhesion in vascular biology: cell adhesion and angiogenesis, J. Clin. Investig. (suppl.), 100, s37 O'Reilly, 1997, Endostatin: an endogenous inhibitor of angiogenesis and tumor growth, Cell, 88, 277, 10.1016/S0092-8674(00)81848-6 Boem, 1997, Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance, Nature (Lond.), 390, 404, 10.1038/37126 Folkman, 1987, Angiogenic factors, Science (Washington, DC), 235, 442, 10.1126/science.2432664 Klagsbrum, 1991, Regulators of angiogenesis, Annu. Rev. Physiol, 53, 217, 10.1146/annurev.ph.53.030191.001245 Folkman, 1992, Angiogenesis, J. Biol. Chem, 267, 10931, 10.1016/S0021-9258(19)49853-0 Leung, 1989, Vascular endothelial growth factor is a secreted angiogenic mitogen, Science (Washington, DC), 246, 1306, 10.1126/science.2479986 Asano, 1999, Wide spectrum of antitumor activity a neutralizing monoclonal antibody to human vascular endothelial growth factor, Jpn. J. Cancer Res, 90, 93, 10.1111/j.1349-7006.1999.tb00671.x