The first demonstration of CYP1A and the ABC protein(s) gene expression and activity in European seabass (Dicentrarchus labrax) primary hepatocytes

Bard, 2000, Multixenobiotic resistance as a cellular defense mechanism in aquatic organisms, Aquat. Toxicol., 48, 357, 10.1016/S0166-445X(00)00088-6 Bard, 2002, Expression of P-glycoprotein in killifish (Fundulus heteroclitus) exposed to environmental xenobiotics, Aquat. Toxicol., 59, 237, 10.1016/S0166-445X(01)00256-9 Behrens, 1998, Microassay for rapid measurement of 7-ethoxyresorufin-O-deethylase activity in intact fish hepatocytes, Mar. Environ. Res., 46, 369, 10.1016/S0141-1136(97)00039-1 Caminada, 2008, Human pharmaceuticals modulate P-gp1 (ABCB1) transport activity in the fish cell line PLHC-1, Aquat. Toxicol., 90, 214, 10.1016/j.aquatox.2008.08.013 Colombo, 2003, Differential modulation of cytochrome P-450 1A and P-glycoprotein expression by aryl hydrocarbon receptor agonists and thyroid hormone in Xenopus laevis liver and intestine, Aquat. Toxicol., 63, 173, 10.1016/S0166-445X(02)00178-9 Costa, 2012, Gene expression analysis of ABC efflux transporters, CYP1A and GSTα in Nile tilapia after exposure to benzo(a)pyrene. Comparative Biochemistry and Physiology Part C: Toxicology &amp, Pharmacology, 155, 469 Deeley, 2006, Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins, Physiol. Rev., 86, 849, 10.1152/physrev.00035.2005 Doi, 2001, P-glycoprotein in the catfish intestine: inducibility by xenobiotics and functional properties, Aquat. Toxicol., 55, 157, 10.1016/S0166-445X(01)00180-1 Ebert, 2005, Induction of phase-1 metabolizing enzymes by oltipraz, flavone and indole-3-carbinol enhance the formation and transport of benzo[a]pyrene sulfate conjugates in intestinal Caco-2 cells, Toxicol. Lett., 158, 140, 10.1016/j.toxlet.2005.03.016 Epel, 1998, Use of multidrug transporters as first lines of defense against toxins in aquatic organisms, Comp. Biochem. Physiol. – Part A: Mol. Integrative Physiol., 120, 23, 10.1016/S1095-6433(98)10005-3 Epel, 2008, Efflux transporters: newly appreciated roles in protection against pollutants, Environ. Sci. Technol., 42, 3914, 10.1021/es087187v Fardel, 1996, P-glycoprotein induction in rat liver epithelial cells in response to acute 3-methylcholanthrene treatment, Biochem. Pharmacol., 51, 1427, 10.1016/0006-2952(96)00081-0 Fernandes, 2007, Chemical residues and biochemical responses in wild and cultured European sea bass (Dicentrarchus labrax L.), Environ. Res., 103, 247, 10.1016/j.envres.2006.05.015 Ferraris, 2002, Early oxidative damage in primary cultured trout hepatocytes: a time course study, Aquat. Toxicol., 59, 283, 10.1016/S0166-445X(02)00007-3 Ferreira, 2010, Assessment of contaminants and biomarkers of exposure in wild and farmed seabass, Ecotoxicol. Environ. Saf., 73, 579, 10.1016/j.ecoenv.2010.01.019 Fischer, 2011, Constitutive mRNA expression and protein activity levels of nine ABC efflux transporters in seven permanent cell lines derived from different tissues of rainbow trout (Oncorhynchus mykiss), Aquat. Toxicol., 101, 438, 10.1016/j.aquatox.2010.11.010 Fischer, 2013, Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos, BMC Biol., 11, 69, 10.1186/1741-7007-11-69 Gravato, 2009, Effects of Benzo(a)pyrene on Seabass (Dicentrarchus labrax L.): Biomarkers, Growth and Behavior, Human Ecol. Risk Assess.: Int. J., 15, 121, 10.1080/10807030802615659 Homolya, 1993, Fluorescent cellular indicators are extruded by the multidrug resistance protein, J. Biol. Chem., 268, 21493, 10.1016/S0021-9258(20)80566-3 Kurelec, 1992, The multixenobiotic resistance mechanism in aquatic organisms, Crit. Rev. Toxicol., 22, 23, 10.3109/10408449209145320 Lampen, 2004, Induction of gene expression of xenobiotic metabolism enzymes and ABC-transport proteins by PAH and a reconstituted PAH mixture in human Caco-2 cells, Biochim. et Biophys. Acta (BBA) – Gene Struct. Expression, 1681, 38, 10.1016/j.bbaexp.2004.09.010 Lemaire-Gony, 1995, Effects of cadmium and benzo(a)pyrene on the immune system, gill ATPase and EROD activity of European sea bass Dicentrarchus labrax, Aquat. Toxicol., 31, 297, 10.1016/0166-445X(94)00073-Y Leslie, 2005, Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense, Toxicol. Appl. Pharmacol., 204, 216, 10.1016/j.taap.2004.10.012 Luckenbach, 2005, Nitromusk and polycyclic musk compounds as long-term inhibitors of cellular xenobiotic defense systems mediated by multidrug transporters, Environ. Health Perspect., 113, 17, 10.1289/ehp.7301 Luckenbach, 2004, Fatal attraction: synthetic musk fragrances compromise multixenobiotic defense systems in mussels, Mar. Environ. Res., 58, 215, 10.1016/j.marenvres.2004.03.017 Mosmann, 1983, Rapid colorimetric assay for cellular growth and survival – application to proliferation and cyto-toxicity assays, J. Immunol. Methods, 65, 55, 10.1016/0022-1759(83)90303-4 Myllynen, 2007, DNA damage caused by benzo(a)pyrene in MCF-7 cells is increased by verapamil, probenecid and PSC833, Toxicol. Lett., 169, 3, 10.1016/j.toxlet.2006.11.006 Naicker, 2007, Establishment and validation of primary hepatocytes of the African sharptooth catfish (Clarias gariepinus), Chemosphere, 68, 69, 10.1016/j.chemosphere.2006.12.037 Paetzold, 2009, Up-regulation of hepatic ABCC2, ABCG2, CYP1A1 and GST in multixenobiotic-resistant killifish (Fundulus heteroclitus) from the Sydney Tar Ponds, Nova Scotia, Canada Mar. Environ. Res., 68, 37, 10.1016/j.marenvres.2009.04.002 Pesonen, 1997, Fish primary hepatocyte culture; an important model for xenobiotic metabolism and toxicity studies, Aquat. Toxicol., 37, 253, 10.1016/S0166-445X(96)00811-9 Pfaffl, 2001, A new mathematical model for relative quantification in real-time RT–PCR, Nucleic Acids Res., 29, e45, 10.1093/nar/29.9.e45 Pivcevic, 2006, Pesticides and their binary combinations as P-glycoprotein inhibitors in NIH 3T3/MDR1 cells, Environ. Toxicol. Pharmacol., 22, 268, 10.1016/j.etap.2006.04.002 Rey-Salgueiro, 2011, Evaluation of 3-hydroxy-benzo[a]pyrene levels in Nile tilapia (Oreochromis niloticus) after waterborne exposure to Benzo[a]pyrene, Toxicol. Environ. Chem., 93, 2040, 10.1080/02772248.2011.606108 Sadar, 2001, Regulation of cytochrome P450 in a primary culture of rainbow trout hepatocytes, In Vitro Cell. Dev. Biol. – Animal, 37, 180, 10.1290/1071-2690(2001)037<0180:ROCPIA>2.0.CO;2 Schirmer, 2006, Proposal to improve vertebrate cell cultures to establish them as substitutes for the regulatory testing of chemicals and effluents using fish, Toxicology, 224, 163, 10.1016/j.tox.2006.04.042 Scholz, 1999, Induction of CYP1A in primary cultures of rainbow trout (Oncorhynchus mykiss) liver cells: concentration-response relationships of four model substances, Ecotoxicol. Environ. Saf., 43, 252, 10.1006/eesa.1999.1786 Schuetz, 1998, Human MDR1and mouse mdr1a P-glycoprotein alter the cellular retention and disposition of erythromycin, but not of retinoic acid or benzo(a)pyrene, Arch. Biochem. Biophys., 350, 340, 10.1006/abbi.1997.0537 Segner, 1998, Isolation and primary culture of teleost hepatocytes, Comp. Biochem. Physiol. – Part A: Mol. Integrative Physiol., 120, 71, 10.1016/S1095-6433(98)10012-0 Smeets, 2002, Cytochrome P4501A induction and testosterone hydroxylation in cultured hepatocytes of four fish species, Chemosphere, 46, 163, 10.1016/S0045-6535(01)00054-6 Smital, 2006, Inhibitors of the ABC transport proteins as emerging pollutants – determination and ecotoxicological relevance, Toxicol. Lett., 164, S43, 10.1016/j.toxlet.2006.06.092 Sturm, 2005, P-glycoprotein and xenobiotic efflux transport in fish, 495, 10.1016/S1873-0140(05)80021-9 Sturm, 2001, Effects of prochloraz and nonylphenol diethoxylate on hepatic biotransformation enzymes in trout: a comparative in vitro/in vivo-assessment using cultured hepatocytes, Aquat. Toxicol., 53, 229, 10.1016/S0166-445X(01)00168-0 Sturm, 2001, Expression and functional activity of P-glycoprotein in cultured hepatocytes from Oncorhynchus mykiss, Am. J. Physiol. Regul. Integr. Comp. Physiol., 281, R1119, 10.1152/ajpregu.2001.281.4.R1119 Tutundjian, 2007, Effect of temperature on the expression of P-glycoprotein in the zebra mussel, Dreissena polymorpha, J. Therm. Biol., 32, 171, 10.1016/j.jtherbio.2007.01.008 Tutundjian, 2002, Genetic and immunological characterisation of a multixenobiotic resistance system in the turbot (Scophthalmus maximus), Comp. Biochem. Physiol. B: Biochem. Mol. Biol., 132, 463, 10.1016/S1096-4959(02)00058-1 Vellonen, 2004, Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity, Eur. J. Pharm. Sci., 23, 181, 10.1016/j.ejps.2004.07.006 Wania, 2007, A global mass balance analysis of the source of perfluorocarboxylic acids in the arctic ocean, Environ. Sci. Technol., 41, 4529, 10.1021/es070124c Winzer, 2000, Short-time induction of oxidative stress in hepatocytes of the European flounder (Platichthys flesus), Mar. Environ. Res., 50, 495, 10.1016/S0141-1136(00)00124-0 Yeh, 1992, A new functional role for P-glycoprotein: efflux pump for benzo(a)pyrene in human breast cancer MCF-7 cells, Cancer Res., 52, 6692 Zaja, 2006, Haemolymph as compartment for efficient and non-destructive determination of P-glycoprotein (Pgp) mediated MXR activity in bivalves, Comp. Biochem. Physiol. C: Toxicol. Pharmacol., 143, 103 Zaja, 2008, Cloning and molecular characterization of apical efflux transporters (ABCB1, ABCB11 and ABCC2) in rainbow trout (Oncorhynchus mykiss) hepatocytes, Aquat. Toxicol., 90, 322, 10.1016/j.aquatox.2008.09.012 Zhou, 2006, Primary cultured cells as sensitive in vitro model for assessment of toxicants-comparison to hepatocytes and gill epithelia, Aquat. Toxicol., 80, 109, 10.1016/j.aquatox.2006.07.021 Zucchi, 2010, Identification of five partial ABC genes in the liver of the Antarctic fish Trematomus bernacchii and sensitivity of ABCB1 and ABCC2 to Cd exposure, Environ. Pollut., 158, 2746, 10.1016/j.envpol.2010.04.012