Imaging Sites of N-WASP Activity in Lamellipodia and Invadopodia of Carcinoma Cells

Pollard, 2003, Cellular motility driven by assembly and disassembly of actin filaments, Cell, 112, 453, 10.1016/S0092-8674(03)00120-X Pollard, 2000, Molecular mechanisms controlling actin filament dynamics in nonmuscle cells, Annu. Rev. Biophys. Biomol. Struct., 29, 545, 10.1146/annurev.biophys.29.1.545 Takenawa, 2001, WASP and WAVE family proteins, J. Cell Sci., 114, 1801, 10.1242/jcs.114.10.1801 Miki, 2003, Regulation of actin dynamics by WASP family proteins, J. Biochem. (Tokyo), 134, 309, 10.1093/jb/mvg146 Rohatgi, 2000, Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate, J. Cell Biol., 150, 1299, 10.1083/jcb.150.6.1299 Kim, 2000, Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein, Nature, 404, 151, 10.1038/35004513 Fukuoka, 2001, A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42, J. Cell Biol., 152, 471, 10.1083/jcb.152.3.471 Carlier, 2000, GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex, J. Biol. Chem., 275, 21946, 10.1074/jbc.M000687200 Higgs, 2000, Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex, J. Cell Biol., 150, 1311, 10.1083/jcb.150.6.1311 Chan, 1998, EGF stimulates an increase in actin nucleation and filament number at the leading edge of the lamellipod in mammary adenocarcinoma cells, J. Cell Sci., 111, 199, 10.1242/jcs.111.2.199 Moreau, 2003, Actin can reorganize into podosomes in aortic endothelial cells, a process controlled by Cdc42 and RhoA, Mol. Cell. Biol., 23, 6809, 10.1128/MCB.23.19.6809-6822.2003 Segall, 1996, EGF stimulates lamellipod extension in metastatic mammary adenocarcinoma cells by an actin-dependent mechanism, Clin. Exp. Metastasis, 14, 61, 10.1007/BF00157687 Rogers, 2003, Molecular requirements for actin-based lamella formation in Drosophila S2 cells, J. Cell Biol., 162, 1079, 10.1083/jcb.200303023 Snapper, 2001, N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility, Nat. Cell Biol., 3, 897, 10.1038/ncb1001-897 Chen, 1989, Proteolytic activity of specialized surface protrusions formed at rosette contact sites of transformed cells, J. Exp. Zool., 251, 167, 10.1002/jez.1402510206 Yamaguchi, 2002, Neural Wiskott-Aldrich syndrome protein is involved in hepatocyte growth factor-induced migration, invasion, and tubulogenesis of epithelial cells, Cancer Res., 62, 2503 Svitkina, 2003, Mechanism of filopodia initiation by reorganization of a dendritic network, J. Cell Biol., 160, 409, 10.1083/jcb.200210174 Lanier, 1999, Mena is required for neurulation and commissure formation, Neuron, 22, 313, 10.1016/S0896-6273(00)81092-2 Rottner, 1999, VASP dynamics during lamellipodia protrusion, Nat. Cell Biol., 1, 321, 10.1038/13040 Peng, 2003, Disruption of the Diaphanous-Related Formin Drf1 Gene Encoding mDia1 Reveals a Role for Drf3 as an Effector for Cdc42, Curr. Biol., 13, 534, 10.1016/S0960-9822(03)00170-2 Chen, 1994, An in vitro cell invasion assay, J. Tissue Cult. Methods, 16, 177, 10.1007/BF01540646