In silico assessment of the effects of various compounds in MEA/hiPSC-CM assays: Modeling and numerical simulations
Tài liệu tham khảo
Blazeski, 2012, Electrophysiological and contractile function of cardiomyocytes derived from human embryonic stem cells, Progress in Biophysics and Molecular Biology, 110, 178, 10.1016/j.pbiomolbio.2012.07.012
Bottino, 2006, Preclinical cardiac safety assessment of pharmaceutical compounds using an integrated systems-based computer model of the heart, Progress in Biophysics and Molecular Biology, 90, 414, 10.1016/j.pbiomolbio.2005.06.006
Boulakia, 2015, Toward transmembrane potential estimation from in vitro multi-electrode field potentials using mathematical modeling, Journal of Pharmacological and Toxicological Methods, 75, 168, 10.1016/j.vascn.2015.08.038
Bowler, 2016, Simulated micro-electrode array recordings from stem cell-derived cardiomyocytes, Journal of Pharmacological and Toxicological Methods, 81, 380, 10.1016/j.vascn.2016.02.148
Braam, 2010, Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes, Stem Cell Research, 4, 107—11 6, 10.1016/j.scr.2009.11.004
Brennan, 2009, Multiscale modelling of drug-induced effects on cardiac electrophysiological activity, European Journal of Pharmaceutical Sciences, 36, 62, 10.1016/j.ejps.2008.09.013
Bucchi, 2013, Identification of the molecular site of ivabradine binding to hcn4 channels, PloS One, 8, e53132, 10.1371/journal.pone.0053132
Carmeliet, 1998, Antiarrhythmic drugs and cardiac ion channels: Mechanisms of action, Progress in Biophysics and Molecular Biology, 70, 1, 10.1016/S0079-6107(98)00002-9
Caspi, 2009, In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes, Stem Cells and Development, 18, 161, 10.1089/scd.2007.0280
Cavero, 2016, Comprehensive in vitro Proarrhythmia Assay (CiPA): Pending issues for successful validation and implementation, Journal of Pharmacological and Toxicological Methods, 10.1016/j.vascn.2016.05.012
Pavarino, 2014, Vol. 13
Doss, 2012, Maximum diastolic potential of human induced pluripotent stem cell-derived cardiomyocytes depends critically on ikr, PloS One, 7, e40288, 10.1371/journal.pone.0040288
Gulrajani, 2001, A membrane-based computer heart model employing parallel processing, Biomedizinische Technik/Biomedical Engineering, 46, 20, 10.1515/bmte.2001.46.s2.20
Harris, 2013, Comparison of electrophysiological data from human-induced pluripotent stem cell-derived cardiomyocytes to functional preclinical safety assays, Toxicological Sciences, 10.1093/toxsci/kft113
He, 2003, Human embryonic stem cells develop into multiple types of cardiac myocytes action potential characterization, Circulation Research, 93, 32, 10.1161/01.RES.0000080317.92718.99
Hille, 2001, Vol. 507
Laflamme, 2007, Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts, Nature Biotechnology, 25, 1 015—1024, 10.1038/nbt1327
Mangi, 2003, Mesenchymal stem cells modified with akt prevent remodeling and restore performance of infarcted hearts, Nature Medicine, 9, 1195—1 201, 10.1038/nm912
Mirams, 2011, Simulation of multiple ion channel block provides improved early prediction of compounds clinical torsadogenic risk, Cardiovascular Research, 91, 53, 10.1093/cvr/cvr044
Mirams, 2012, Application of cardiac electrophysiology simulations to pro-arrhythmic safety testing, British Journal of Pharmacology, 167, 932, 10.1111/j.1476-5381.2012.02020.x
Moulin, 2008, A new 3-D finite-element model based on thin-film approximation for microelectrode array recording of extracellular action potential, Biomedical Engineering, IEEE Transactions on, 55, 683, 10.1109/TBME.2007.903522
Multichannel systems, Microelectrode array (mea) manual. http://www.multichannelsystems.com/sites/multichannelsystems.com/files/documents/manuals/MEA_Manual.pdf.
Paci, 2013, Computational models of ventricular- and atrial-like human induced pluripotent stem cell derived cardiomyocytes, Annals of Biomedical Engineering, 41, 2334, 10.1007/s10439-013-0833-3
Paci, 2014, Computational modeling supports induced pluripotent stem cell-derived cardiomyocytes reliability as a model for human lqt3, 69
Pekkanen-Mattila, 2010, Human embryonic stem cell-derived cardiomyocytes: Demonstration of a portion of cardiac cells with fairly mature electrical phenotype, Experimental Biology and Medicine, 235, 522, 10.1258/ebm.2010.009345
Peng, 2010, The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes, Journal of Pharmacological and Toxicological Methods, 61, 277, 10.1016/j.vascn.2010.01.014
Qu, 2015, Proarrhythmia risk assessment in human induced pluripotent stem cell-derived cardiomyocytes using the maestro mea platform, Toxicological Sciences, 147, 286, 10.1093/toxsci/kfv128
Robertson, 2013, Concise review: Maturation phases of human pluripotent stem cell-derived cardiomyocytes, Stem Cells, 31, 829, 10.1002/stem.1331
Sundnes, 2007, Vol. 1
Sundnes, 2005, An operator splitting method for solving the bidomain equations coupled to a volume conductor model for the torso, Mathematical Biosciences, 194, 233, 10.1016/j.mbs.2005.01.001
Takahashi, 2006, Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors, Cell, 126, 663, 10.1016/j.cell.2006.07.024
Zahradníková, 2007, Competitive and cooperative effects of bay k8644 on the l-type calcium channel current inhibition by calcium channel antagonists, Journal of Pharmacology and Experimental Therapeutics, 322, 638, 10.1124/jpet.107.122176
Zemzemi, 2013, Computational assessment of drug-induced effects on the electrocardiogram: From ion channel to body surface potentials, British Journal of Pharmacology, 168, 718, 10.1111/j.1476-5381.2012.02200.x
Zemzemi, 2015, Effects of L-type calcium channel and human ether-a-go-go related gene blockers on the electrical activity of the human heart: A simulation study, Europace, 17, 326, 10.1093/europace/euu122