Immunomodulatory effect of human umbilical cord Wharton’s jelly-derived mesenchymal stem cells on lymphocytes

Chen, 2009, Endothelial differentiation of Wharton’s jelly-derived mesenchymal stem cells in comparison with bone marrow-derived mesenchymal stem cells, Exp. Hematol., 37, 629, 10.1016/j.exphem.2009.02.003 Conget, 2000, Adenoviral-mediated gene transfer into ex vivo expanded human bone marrow mesenchymal progenitor cells, Exp. Hematol., 28, 382, 10.1016/S0301-472X(00)00134-X Muraglia, 2000, Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model, J. Cell Sci., 113, 1161, 10.1242/jcs.113.7.1161 Lou, 1999, Gene therapy: adenovirus-mediated human bone morphogenetic protein-2 gene transfer induces mesenchymal progenitor cell proliferation and differentiation in vitro and bone formation in vivo, J. Orthop. Res., 17, 43, 10.1002/jor.1100170108 Mbalaviele, 1999, Human mesenchymal stem cells promote human osteoclast differentiation from CD34+ bone marrow hematopoietic progenitors, Endocrinology, 140, 3736, 10.1210/endo.140.8.6880 Toma, 2002, Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart, Circulation, 105, 93, 10.1161/hc0102.101442 Woodbury, 2000, Adult rat and human bone marrow stromal cells differentiate into neurons, J. Neurosci. Res., 61, 364, 10.1002/1097-4547(20000815)61:4<364::AID-JNR2>3.0.CO;2-C Mueller, 2001, Age-related decline in the osteogenic potential of human bone marrow cells cultured in three-dimensional collagen sponges, J. Cell. Biochem., 82, 583, 10.1002/jcb.1174 Stenderup, 2003, Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells, Bone, 33, 919, 10.1016/j.bone.2003.07.005 Krampera, 2003, Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide, Blood, 101, 3722, 10.1182/blood-2002-07-2104 Weiss, 2008, Immune properties of human umbilical cord Wharton’s jelly-derived cells, Stem Cells, 26, 2865, 10.1634/stemcells.2007-1028 Le Blanc, 2003, Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex, Scand. J. Immunol., 57, 11, 10.1046/j.1365-3083.2003.01176.x Hematti, 2008, Role of mesenchymal stromal cells in solid organ transplantation, Transplant. Rev. (Orlando), 22, 262, 10.1016/j.trre.2008.05.002 Bartholomew, 2002, Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo, Exp. Hematol., 30, 42, 10.1016/S0301-472X(01)00769-X Yanez, 2006, Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease, Stem cells, 24, 2582, 10.1634/stemcells.2006-0228 Zhang, 2005, Human bone marrow stromal cell treatment improves neurological functional recovery in EAE mice, Exp. Neurol., 195, 16, 10.1016/j.expneurol.2005.03.018 Djouad, 2005, Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis, Arthritis Rheum., 52, 1595, 10.1002/art.21012 Karussis, 2008, Immunomodulation and neuroprotection with mesenchymal bone marrow stem cells (MSCs): a proposed treatment for multiple sclerosis and other neuroimmunological/neurodegenerative diseases, J. Neurol. Sci., 265, 131, 10.1016/j.jns.2007.05.005 Magatti, 2008, Human amnion mesenchyme harbors cells with allogeneic T-cell suppression and stimulation capabilities, Stem Cells, 26, 182, 10.1634/stemcells.2007-0491 Asari, 2009, Mesenchymal stem cells suppress B-cell terminal differentiation, Exp. Hematol., 37, 604, 10.1016/j.exphem.2009.01.005 Spaggiari, 2008, Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2, Blood, 111, 1327, 10.1182/blood-2007-02-074997 English, 2008, Murine mesenchymal stem cells suppress dendritic cell migration, maturation and antigen presentation, Immunol. Lett, 115, 50, 10.1016/j.imlet.2007.10.002 Nasef, 2007, Identification of IL-10 and TGF-beta transcripts involved in the inhibition of T-lymphocyte proliferation during cell contact with human mesenchymal stem cells, Gene Expr., 13, 217, 10.3727/000000006780666957 Bettelli, 2006, Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells, Nature, 441, 235, 10.1038/nature04753 Huber, 2008, P38 MAP kinase signaling is required for the conversion of CD4+CD25- T cells into iTreg, PLoS ONE, 3, e3302, 10.1371/journal.pone.0003302 Zhang, 2009, Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2-dependent regulatory dendritic cell population, Blood, 113, 46, 10.1182/blood-2008-04-154138 Meisel, 2004, Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation, Blood, 103, 4619, 10.1182/blood-2003-11-3909 Zvaifler, 2000, Mesenchymal precursor cells in the blood of normal individuals, Arthritis Res., 2, 477, 10.1186/ar130 Campagnoli, 2001, Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow, Blood, 98, 2396, 10.1182/blood.V98.8.2396 Williams, 1999, Cells isolated from adult human skeletal muscle capable of differentiating into multiple mesodermal phenotypes, Am. Surg., 65, 22, 10.1177/000313489906500106 Peng, 2006, Umbilical cord stricture and overcoiling are common causes of fetal demise, Pediatr. Dev. Pathol., 9, 14, 10.2350/05-05-0051.1 Trevisanuto, 2007, Overcoiling of the umbilical cord, J. Pediatr., 150, 112, 10.1016/j.jpeds.2006.11.042 Sarugaser, 2005, Human umbilical cord perivascular (HUCPV) cells: a source of mesenchymal progenitors, Stem Cells, 23, 220, 10.1634/stemcells.2004-0166 Karahuseyinoglu, 2007, Biology of stem cells in human umbilical cord stroma: in situ and in vitro surveys, Stem Cells, 25, 319, 10.1634/stemcells.2006-0286 Wang, 2004, Mesenchymal stem cells in the Wharton’s jelly of the human umbilical cord, Stem Cells, 22, 1330, 10.1634/stemcells.2004-0013 Weiss, 2006, Human umbilical cord matrix stem cells: preliminary characterization and effect of transplantation in a rodent model of Parkinson’s disease, Stem Cells, 24, 781, 10.1634/stemcells.2005-0330 Fu, 2006, Conversion of human umbilical cord mesenchymal stem cells in Wharton’s jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism, Stem Cells, 24, 115, 10.1634/stemcells.2005-0053 Lund, 2007, Cells isolated from umbilical cord tissue rescue photoreceptors and visual functions in a rodent model of retinal disease, Stem Cells, 25, 602, 10.1634/stemcells.2006-0308erratum Jomura, 2007, Potential treatment of cerebral global ischemia with Oct-4+ umbilical cord matrix cells, Stem Cells, 25, 98, 10.1634/stemcells.2006-0055 Rachakatla, 2007, Development of human umbilical cord matrix stem cell-based gene therapy for experimental lung tumors, Cancer Gene Ther., 14, 828, 10.1038/sj.cgt.7701077 Wang, 2009, The immunomodulatory activity of human umbilical cord blood-derived mesenchymal stem cells in vitro, Immunology, 126, 220, 10.1111/j.1365-2567.2008.02891.x Medicetty, 2004, Transplantation of pig stem cells into rat brain: proliferation during the first 8 weeks, Exp. Neurol., 190, 32, 10.1016/j.expneurol.2004.06.023 Bian, 2009, In vitro and in vivo immunosuppressive characteristics of hepatocyte growth factor-modified murine mesenchymal stem cells, In vivo, 23, 21 Bommireddy, 2003, TGF-beta 1 regulates lymphocyte homeostasis by preventing activation and subsequent apoptosis of peripheral lymphocytes, J. Immunol., 170, 4612, 10.4049/jimmunol.170.9.4612 Xu, 2007, The role of IL-6 in inhibition of lymphocyte apoptosis by mesenchymal stem cells, Biochem. Biophys. Res. Commun., 361, 745, 10.1016/j.bbrc.2007.07.052 Tse, 2003, Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation, Transplantation, 75, 389, 10.1097/01.TP.0000045055.63901.A9