A balanced view of choroid plexus structure and function: Focus on adult humans

Experimental Neurology - Tập 267 - Trang 78-86 - 2015
Reynold Spector1, Richard F. Keep2, S. Robert Snodgrass3, Quentin R. Smith4, Conrad E. Johanson5
1Department of Medicine, Robert Wood Johnson Medical School, Piscataway, NJ 08554, USA
2Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, MI 48105, USA
3Departments of Neurology and Pediatrics, Harbor-UCLA Medical Center, David Geffen UCLA School of Medicine, Torrance, CA 90502, USA
4Department of Pharmaceutical Sciences, School of Pharmacy, Amarillo, TX 79106, USA
5Department of Neurosurgery, Alpert Medical School at Brown University, Providence, RI 02903, USA

Tài liệu tham khảo

Aldred, 1995, The cerebral expression of plasma protein genes in different species, Comp. Biochem. Physiol. B Biochem. Mol. Biol., 111, 1, 10.1016/0305-0491(94)00229-N Angeletti, 1997, The choroid plexus epithelium is the site of the organic anion transport protein in the brain, Proc. Natl. Acad. Sci. U. S. A., 94, 283, 10.1073/pnas.94.1.283 Angelow, 2003, Functional characterisation of the active ascorbic acid transport into cerebrospinal fluid using primary cultured choroid plexus cells, Brain Res., 988, 105, 10.1016/S0006-8993(03)03350-X Ballermann, 2007, Resolved: capillary endothelium is a major contributor to the glomerular filtration barrier, J. Am. Soc. Nephrol., 18, 2432, 10.1681/ASN.2007060687 Bateman, 2012, The measurement of CSF flow through the aqueduct in normal and hydrocephalic children: from where does it come, to where does it go?, Childs Nerv. Syst., 28, 55, 10.1007/s00381-011-1617-4 Bradbury, 1980, The role of the lymphatic system in drainage of cerebrospinal fluid and aqueous humour, J. Physiol., 299, 353, 10.1113/jphysiol.1980.sp013129 Bradbury, 1964, The transport of urea, creatinine and certain monosaccharides between blood and fluid perfusing the cerebral ventricular system of rabbits, J. Physiol., 170, 195, 10.1113/jphysiol.1964.sp007323 Brinker, 2014, A new look at cerebrospinal fluid circulation, Fluids Barriers CNS, 11, 10, 10.1186/2045-8118-11-10 Buishas, 2014, A computational model of cerebrospinal fluid production and reabsorption driven by Starling forces, Croat. Med. J., 55, 481, 10.3325/cmj.2014.55.481 Carro, 2005, Choroid plexus megalin is involved in neuroprotection by serum insulin-like growth factor I, J. Neurosci., 25, 10884, 10.1523/JNEUROSCI.2909-05.2005 Chen, 2010, The influence of cerebrospinal fluid turnover on age-related changes in cerebrospinal fluid protein concentrations, Neurosci. Lett., 476, 138, 10.1016/j.neulet.2010.04.015 Chodobski, 2001, Choroid plexus: target for polypeptides and site of their synthesis, Microsc. Res. Tech., 52, 65, 10.1002/1097-0029(20010101)52:1<65::AID-JEMT9>3.0.CO;2-4 Cirrito, 2005, P-glycoprotein deficiency at the blood–brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model, J. Clin. Invest., 115, 3285, 10.1172/JCI25247 Cornford, 1997, Mitochondrial content of choroid plexus epithelium, Exp. Brain Res., 116, 399, 10.1007/PL00005768 Cserr, 1988, Role of secretion and bulk flow of brain interstitial fluid in brain volume regulation, Ann. N. Y. Acad. Sci., 529, 9, 10.1111/j.1749-6632.1988.tb51415.x Damkier, 2013, Cerebrospinal fluid secretion by the choroid plexus, Physiol. Rev., 93, 1847, 10.1152/physrev.00004.2013 Davson, 1970, The effects of some inhibitors and accelerators of sodium transport on the turnover of 22Na in the cerebrospinal fluid and the brain, J. Physiol., 209, 131, 10.1113/jphysiol.1970.sp009159 Davson, 1987 de Rougemont, 1960, Fluid formed by choroid plexus; a technique for its collection and a comparison of its electrolyte composition with serum and cisternal fluids, J. Neurophysiol., 23, 485, 10.1152/jn.1960.23.5.485 Diamond, 1971, Standing-gradient model of fluid transport in epithelia, Fed. Proc., 30, 6 Dohrmann, 1970, Dark and light epithelial cells in the choroid plexus of mammals, J. Ultrastruct. Res., 32, 268, 10.1016/S0022-5320(70)80007-7 Faraci, 1990, Effect of vasopressin on production of cerebrospinal fluid: possible role of vasopressin (V1)-receptors, Am. J. Physiol., 258, R94 Farrell, 1992, GLUT-1 glucose transporter is present within apical and basolateral membranes of brain epithelial interfaces and in microvascular endothelia with and without tight junctions, J. Histochem. Cytochem., 40, 193, 10.1177/40.2.1552163 Ghersi-Egea, 1996, Rapid distribution of intraventricularly administered sucrose into cerebrospinal fluid cisterns via subarachnoid velae in rat, Neuroscience, 75, 1271, 10.1016/0306-4522(96)00281-3 Hakvoort, 1998, The polarity of choroid plexus epithelial cells in vitro is improved in serum-free medium, J. Neurochem., 71, 1141, 10.1046/j.1471-4159.1998.71031141.x Hallaert, 2012, Endoscopic coagulation of choroid plexus hyperplasia, J. Neurosurg. Pediatr., 9, 169, 10.3171/2011.11.PEDS11154 Hammarstrom, 1966, Autoradiographic studies on the distribution of C14-labelled ascorbic acid and dehydroascorbic acid, Acta Physiol. Scand., 289, 1, 10.1111/j.1748-1716.1966.tb03661.x Igarashi, 2014, Water influx into cerebrospinal fluid is primarily controlled by aquaporin-4, not by aquaporin-1: 17O JJVCPE MRI study in knockout mice, Neuroreport, 25, 39, 10.1097/WNR.0000000000000042 Javaheri, 1993, Bumetanide decreases canine cerebrospinal fluid production. In vivo evidence for NaCl cotransport in the central nervous system, J. Clin. Invest., 92, 2257, 10.1172/JCI116829 Johanson, 1980, Permeability and vascularity of the developing brain: cerebellum vs cerebral cortex, Brain Res., 190, 3, 10.1016/0006-8993(80)91155-5 Johanson, 1992, Maturational differences in acetazolamide-altered pH and HCO3 of choroid plexus, cerebrospinal fluid, and brain, Am. J. Physiol., 262, R909 Johanson, 2008, Multiplicity of cerebrospinal fluid functions: new challenges in health and disease, Cerebrospinal Fluid Res., 5, 10, 10.1186/1743-8454-5-10 Johnston, 2004, Evidence of connections between cerebrospinal fluid and nasal lymphatic vessels in humans, non-human primates and other mammalian species, Cerebrospinal Fluid Res., 1, 2, 10.1186/1743-8454-1-2 Johnston, 2005, Subarachnoid injection of microfil reveals connections between cerebrospinal fluid and nasal lymphatics in the non-human primate, Neuropathol. Appl. Neurobiol., 31, 632, 10.1111/j.1365-2990.2005.00679.x Kao, 2011, Severe neurologic impairment in mice with targeted disruption of the electrogenic sodium bicarbonate cotransporter NBCe2 (Slc4a5 gene), J. Biol. Chem., 286, 32563, 10.1074/jbc.M111.249961 Kapoor, 2008, Cerebrospinal fluid outflow: an evolving perspective, Brain Res. Bull., 77, 327, 10.1016/j.brainresbull.2008.08.009 Keep, 1990, A morphometric study on the development of the lateral ventricle choroid plexus, choroid plexus capillaries and ventricular ependyma in the rat, Brain Res. Dev. Brain Res., 56, 47, 10.1016/0165-3806(90)90163-S Keep, 1986, A morphometric analysis of the development of the fourth ventricle choroid plexus in the rat, Brain Res., 392, 77, 10.1016/0165-3806(86)90234-8 Keep, 1994, Potassium cotransport at the rat choroid plexus, Am. J. Physiol., 267, C1616, 10.1152/ajpcell.1994.267.6.C1616 Klosovskii, 1963 Liddelow, 2013, Mechanisms that determine the internal environment of the developing brain: a transcriptomic, functional and ultrastructural approach, PLoS ONE, 8, e65629, 10.1371/journal.pone.0065629 Lorenzo, 1972, Leucine transport from the ventricles and the cranial subarachnoid space in the cat, J. Neurochem., 19, 1287, 10.1111/j.1471-4159.1972.tb01454.x MacAulay, 2010, Water transport between CNS compartments: contributions of aquaporins and cotransporters, Neuroscience, 168, 941, 10.1016/j.neuroscience.2009.09.016 McCarthy, 1974, The effect of acetazolamide and furosemide on cerebrospinal fluid production and choroid plexus carbonic anhydrase activity, J. Pharmacol. Exp. Ther., 189, 194 Millar, 2007, Ion channel diversity, channel expression and function in the choroid plexuses, Cerebrospinal Fluid Res., 4, 8, 10.1186/1743-8454-4-8 Miller, 2004, Confocal imaging of xenobiotic transport across the choroid plexus, Adv. Drug Deliv. Rev., 56, 1811, 10.1016/j.addr.2004.07.010 Miner, 1972, Composition of fluid obtained from choroid plexus tissue isolated in a chamber in situ, J. Physiol., 227, 127, 10.1113/jphysiol.1972.sp010023 Murphy, 1989, Acidosis, acetazolamide, and amiloride: effects on 22Na transfer across the blood–brain and blood–CSF barriers, J. Neurochem., 52, 1058, 10.1111/j.1471-4159.1989.tb01847.x Murphy, 1990, Na(+)–H(+) exchange in choroid plexus and CSF in acute metabolic acidosis or alkalosis, Am. J. Physiol., 258, F1528 Nagaraja, 2005, In normal rat, intraventricularly administered insulin-like growth factor-1 is rapidly cleared from CSF with limited distribution into brain, Cerebrospinal Fluid Res., 2, 5, 10.1186/1743-8454-2-5 Netsky, 1975 Nigam, 2015, The organic anion transporter (OAT) family: a systems biology perspective, Physiol. Rev., 95, 83, 10.1152/physrev.00025.2013 Nilsson, 1992, Circadian variation in human cerebrospinal fluid production measured by magnetic resonance imaging, Am. J. Physiol., 262, R20 Nilsson, 1994, The nocturnal increase in human cerebrospinal fluid production is inhibited by a beta 1-receptor antagonist, Am. J. Physiol., 267, R1445 Ohtsuki, 2003, In vitro study of the functional expression of organic anion transporting polypeptide 3 at rat choroid plexus epithelial cells and its involvement in the cerebrospinal fluid-to-blood transport of estrone-3-sulfate, Mol. Pharmacol., 63, 532, 10.1124/mol.63.3.532 Oldendorf, 1970, Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard, Brain Res., 24, 372, 10.1016/0006-8993(70)90123-X Oreskovic, 2010, The formation of cerebrospinal fluid: nearly a hundred years of interpretations and misinterpretations, Brain Res. Rev., 64, 241, 10.1016/j.brainresrev.2010.04.006 Oreskovic, 2014, Measurement of cerebrospinal fluid formation and absorption by ventriculo-cisternal perfusion: what is really measured?, Croat. Med. J., 55, 317, 10.3325/cmj.2014.55.317 Oreskovic, 2014, A new look at cerebrospinal fluid movement, Fluids Barriers CNS, 11, 16, 10.1186/2045-8118-11-16 Oreskovikic, 2005, The investigation of cerebrospinal fluid formation by ventriculo-aqueductal perfusion method in cats, Acta Neurochir. Suppl., 95, 433, 10.1007/3-211-32318-X_89 Pardridge, 2011, Drug transport in brain via the cerebrospinal fluid, Fluids Barriers CNS, 8, 7, 10.1186/2045-8118-8-7 Pardridge, 2012, Drug transport across the blood–brain barrier, J. Cereb. Blood Flow Metab., 32, 1959, 10.1038/jcbfm.2012.126 Parmelee, 1989, Development of potassium transport capability by choroid plexus of infant rats, Am. J. Physiol., 256, R786 Pliushcheva, 1994, CSF dynamics in patients with meningiomas, Acta Neurochir. Suppl. (Wien), 60, 174 Pollay, 2010, The function and structure of the cerebrospinal fluid outflow system, Cerebrospinal Fluid Res., 7, 9, 10.1186/1743-8454-7-9 Pollay, 1967, Secretion of cerebrospinal fluid by the ventricular ependyma of the rabbit, Am. J. Physiol., 213, 1031, 10.1152/ajplegacy.1967.213.4.1031 Praetorius, 2006, Distribution of sodium transporters and aquaporin-1 in the human choroid plexus, Am. J. Physiol. Cell Physiol., 291, C59, 10.1152/ajpcell.00433.2005 Praetorius, 2004, A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells, Am. J. Physiol. Cell Physiol., 286, C601, 10.1152/ajpcell.00240.2003 Proescholdt, 2000, Studies of cerebrospinal fluid flow and penetration into brain following lateral ventricle and cisterna magna injections of the tracer [14C]inulin in rat, Neuroscience, 95, 577, 10.1016/S0306-4522(99)00417-0 Shen, 2007, Impact of genetic knockout of PEPT2 on cefadroxil pharmacokinetics, renal tubular reabsorption, and brain penetration in mice, Drug Metab. Dispos., 35, 1209, 10.1124/dmd.107.015263 Smith, 1980, Effect of carbonic anhydrase inhibitors and acidosis in choroid plexus epithelial cell sodium and potassium, J. Pharmacol. Exp. Ther., 215, 673 Smith, 1991, Chloride efflux from isolated choroid plexus, Brain Res., 562, 306, 10.1016/0006-8993(91)90636-A Smith, 1986, Cerebrovascular permeability coefficients to sodium, potassium, and chloride, J. Neurochem., 46, 1732, 10.1111/j.1471-4159.1986.tb08491.x Smith, 1982, Kinetic analysis of [36Cl]−, [22Na]− and [3H]mannitol uptake into the in vivo choroid plexus–cerebrospinal fluid brain system: ontogeny of the blood brain and blood–CSF barriers, Brain Res., 255, 181, 10.1016/0165-3806(82)90019-0 Smith, 2004, Peptide and peptide analog transport systems at the blood–CSF barrier, Adv. Drug Deliv. Rev., 56, 1765, 10.1016/j.addr.2004.07.008 Smith, 2007, Choroid plexus hyperplasia: surgical treatment and immunohistochemical results. Case report, J. Neurosurg., 107, 255 Souweidane, 2014, Editorial: combined choroid plexus coagulation and endoscopic third ventriculostomy: is North America ready?, J. Neurosurg. Pediatr., 14, 221, 10.3171/2014.4.PEDS1450 Speake, 2004, Ion channels in epithelial cells of the choroid plexus isolated from the lateral ventricle of rat brain, Brain Res., 1005, 60, 10.1016/j.brainres.2004.01.034 Speake, 2003, Expression of aquaporin 1 and aquaporin 4 water channels in rat choroid plexus, Biochim. Biophys. Acta, 1609, 80, 10.1016/S0005-2736(02)00658-2 Spector, 1981, Penetration of ascorbic acid from cerebrospinal fluid into brain, Exp. Neurol., 72, 645, 10.1016/0014-4886(81)90013-3 Spector, 1986, Ceftriaxone pharmacokinetics in the central nervous system, J. Pharmacol. Exp. Ther., 236, 380 Spector, 2009, Nutrient transport systems in brain: 40years of progress, J. Neurochem., 111, 315, 10.1111/j.1471-4159.2009.06326.x Spector, 2010, Nature and consequences of mammalian brain and CSF efflux transporters: four decades of progress, J. Neurochem., 112, 13, 10.1111/j.1471-4159.2009.06451.x Spector, 2014, Vitamin transport diseases of brain: focus on folates, thiamine and riboflavin, Brain Dis. Ther., 3, 1 Spector, 1977, Ascorbic acid transport by a clonal line of pheochromocytoma cells, Brain Res., 136, 131, 10.1016/0006-8993(77)90137-8 Spector, 2010, Vectorial ligand transport through mammalian choroid plexus, Pharm. Res., 27, 2054, 10.1007/s11095-010-0162-2 Spector, 2013, Sustained choroid plexus function in human elderly and Alzheimer's disease patients, Fluids Barriers CNS, 10, 28, 10.1186/2045-8118-10-28 Spector, 2014, The nexus of vitamin homeostasis and DNA synthesis and modification in mammalian brain, Mol. Brain, 7, 3, 10.1186/1756-6606-7-3 Stone, 2014, Combined endoscopic third ventriculostomy and choroid plexus cauterization as primary treatment for infant hydrocephalus: a prospective North American series, J. Neurosurg. Pediatr., 14, 439, 10.3171/2014.7.PEDS14152 Sweet, 1950, Studies of formation, flow and absorption of cerebrospinal fluid. II. Studies with heavy water in the normal man, Surg. Forum, 376 Sweet, 2001, Ventricular choline transport: a role for organic cation transporter 2 expressed in choroid plexus, J. Biol. Chem., 276, 41611, 10.1074/jbc.M108472200 Tang, 2014, Neuropharmacokinetics of two investigational compounds in rats: divergent temporal profiles in the brain and cerebrospinal fluid, Biochem. Pharmacol., 91, 543, 10.1016/j.bcp.2014.07.023 Thomas, 2001, Leptin transport at the blood–cerebrospinal fluid barrier using the perfused sheep choroid plexus model, Brain Res., 895, 283, 10.1016/S0006-8993(01)02116-3 Varatharajan, 2009, The transport of anti-HIV drugs across blood–CNS interfaces: summary of current knowledge and recommendations for further research, Antivir. Res., 82, A99, 10.1016/j.antiviral.2008.12.013 Vates, 1964, Na–K activated adenosine triphosphatase formation of cerebrospinal fluid in the cat, Am. J. Physiol., 206, 1165, 10.1152/ajplegacy.1964.206.5.1165 Walter, 1999, Distinct sites of insulin-like growth factor (IGF)-II expression and localization in lesioned rat brain: possible roles of IGF binding proteins (IGFBPs) in the mediation of IGF-II activity, Endocrinology, 140, 520, 10.1210/endo.140.1.6463 Warf, 2012, Long-term outcome for endoscopic third ventriculostomy alone or in combination with choroid plexus cauterization for congenital aqueductal stenosis in African infants, J. Neurosurg. Pediatr., 10, 108, 10.3171/2012.4.PEDS1253 Welch, 1963, Secretion of cerebrospinal fluid by choroid plexus of the rabbit, Am. J. Physiol., 205, 617, 10.1152/ajplegacy.1963.205.3.617 Welch, 1975 Wolburg, 2010, Choroid plexus: biology and pathology, Acta Neuropathol., 119, 75, 10.1007/s00401-009-0627-8 Zeuthen, 1994, Cotransport of K+, Cl- and H2O by membrane proteins from choroid plexus epithelium of Necturus maculosus, J Physiol, 478, 203, 10.1113/jphysiol.1994.sp020243 Zheng, 2005