Circadian chronotherapy for human cancers

Lévi, 1997, Chronopharmacology of anticancer agents, 299, 10.1007/978-3-662-09355-9_11

Mormont, 1998, Non-invasive estimation of the circadian rhythm in serum cortisol in patients with ovarian or colorectal cancer, Int J Cancer, 78, 421, 10.1002/(SICI)1097-0215(19981109)78:4<421::AID-IJC5>3.0.CO;2-W

Balsalobre, 1998, A serum shock induces circadian gene expression in mammalian tissue culture cells, Cell, 93, 929, 10.1016/S0092-8674(00)81199-X

Dunlap, 1999, Molecular bases for circadian clocks, Cell, 96, 271, 10.1016/S0092-8674(00)80566-8

Shearman, 2000, Interacting molecular loops in the mammalian circadian clock, Science, 288, 1013, 10.1126/science.288.5468.1013

Moore, 1996, Entrainment pathways and the functional organization of the circadian system, Prog Brain Res, 111, 103, 10.1016/S0079-6123(08)60403-3

Cassone, 1998, Melatonin's role in vertebrate circadian rhythms, Chronobiol Int, 15, 457, 10.3109/07420529808998702

Boughattas, 1989, Circadian rhythm in toxicities and tissue uptake of 1,2-diamminocyclohexane (trans-1) oxalatoplatinum (II) in mice, Cancer Res, 49, 3362

Ohdo, 1997, Cell cycle-dependent chronotoxicity of irinotecan hydrochloride in mice. J, Pharmacol Exp Ther, 283, 1383

Boughattas, 1990, Stable circadian mechanisms of toxicity of two platinum analogs (cisplatin and carboplatin) despite repeated dosages in mice. J, Pharm Exp Ther, 255, 672

Zhang, 1993, Relationship between circadian-dependent toxicity of 5-fluorodeoxyuridine and circadian rhythms of pyrimidine enzymes: possible relevance to fluoropyrimidine chemotherapy, Cancer Res, 53, 2816

Li, 1997, Pharmacologic modulation of reduced glutathione (GSH) circadian rhythms by buthionine sulfoximine (BSO): relationship with cisplatin (CDDP) toxicity in mice, Toxicol Appl Pharmacol, 143, 281, 10.1006/taap.1996.8088

Tampellini, 1998, Circadian rhythm in docetaxel tolerability and efficacy in mice, Cancer Res, 58, 3896

Focan, 1995, Circadian rhythms and cancer chemotherapy, Pharmacol Ther, 67, 1, 10.1016/0163-7258(95)00009-6

Filipski, 1999, Relationship between circadian rhythm of vinorelbine toxicity and efficacy in P388-bearing mice, J Pharm Exp Ther, 289, 231

Sothern, 1989, Control of a murine plasmacytoma with doxorubicin-cisplatin: dependence on circadian stage of treatment, J Natl Cancer Inst, 81, 135, 10.1093/jnci/81.2.135

D'attino, 2000, Irinotecan (CPT-11) and oxaliplatin (l-OHP) synergistic activity at specific circadian times in tumor-bearing mice, Proc Am Assoc Cancer Res, 91, 1268

Granda, 2001, Experimental chronotherapy of mouse mammary adenocarcinoma MA13/C with docetaxel and doxorubicin as single agents and in combination, Cancer Res, 61, 1996

Smaaland, 1991, DNA synthesis in human bonne marrow is circadian stage dependent, Blood, 77, 2603, 10.1182/blood.V77.12.2603.2603

Bjarnason, 1999, Circadian variation in the expression of cell-cycle proteins in human oral epithelium, Am J Pathol, 154, 613, 10.1016/S0002-9440(10)65306-0

Bjarnason, 2000, Circadian expression of clock genes in human oral epithelium and skin: association with cell cycle progression, Am J Pathol

Harris, 1990, Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels: evidence for circadian variation of plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion, Cancer Res, 50, 197

Langouët, 1995, Plasma concentration of 5-fluorouracil and mononuclear cell dihydropyrimidine dehydrogenase activity in patients treated with different chronomodulated schedules, Biol Rhythm Res, 26, 409

Lévi, 2001, Chronomodulation of chemotherapy against metastatic colorectal cancer

Petit, 1988, Circadian varying plasma concentration of 5-FU during 5-day continuous venous infusion at constant rate in cancer patients, Cancer Res, 48, 1676

Metzger, 1994, Spontaneous or imposed circadian changes in plasma concentrations of 5-fluorouracil coadministered with folinic acid and oxaliplatin: relationship with mucosal toxicity in cancer patients, Clin Pharm Ther, 56, 190, 10.1038/clpt.1994.123

Bressolle, 1999, Circadian rhythm of 5-fluorouracil population pharmacokinetics in patients with metastatic colorectal cancer, Cancer Chemother Pharmacol, 44, 295, 10.1007/s002800050980

Codacci-Pisanelli, 1995, Antitumor activity, toxicity and inhibition of thymidylate synthase of prolonged administration of 5-fluorouracil in mice, Eur J Cancer, 31A, 1517, 10.1016/0959-8049(95)00218-8

Takimoto, 1999, High inter- and intrapatient variation in 5-fluorouracil plasma concentrations during a prolonged drug infusion, Clin Cancer Res, 5, 1347

King, 1997, Positional cloning of the mouse circadian clock gene, Cell, 89, 641, 10.1016/S0092-8674(00)80245-7

Halberg, 1981, International geographic studies of oncological interest on chronobiological variables, 553

Mormont, 1997, ircadian-system alterations during cancer processes: a review, Int J Cancer, 70, 241, 10.1002/(SICI)1097-0215(19970117)70:2<241::AID-IJC16>3.0.CO;2-L

Hrushesky, 1985, Circadian timing of cancer chemotherapy, Science, 228, 73, 10.1126/science.3883493

Lévi, 1990, Therapy of advanced ovarian cancer with 4′-0-tetrahydropyranyl doxorubicin (THP) and cisplatin: a phase II trial with an evaluation of circadian timing and dose intensity, J Clin Oncol, 8, 705, 10.1200/JCO.1990.8.4.705

1998, Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer, J Clin Oncol, 16, 301, 10.1200/JCO.1998.16.1.301

Adler, 1994, Chronotherapy with 5-fluorouracil and folinic acid in advanced colorectal carcinoma. Results of a chronopharmacologic phase I trial, Cancer, 73, 2905, 10.1002/1097-0142(19940615)73:12<2905::AID-CNCR2820731206>3.0.CO;2-J

Falcone, 1999, Infusions of fluorouracil and leucovorin: effects of the timing and semi-intermittency of drug delivery, Oncology, 57, 195, 10.1159/000012031

Roemeling, 1989, Circadian patterning of continuous floxuridine infusion reduces toxicity and allows higher dose intensity in patients with widespread cancer. J, Clin Oncol, 7, 1710, 10.1200/JCO.1989.7.11.1710

Lévi, 1992, A chronopharmacologic phase II clinical trial with 5-fluorouracil, folinic acid and oxaliplatin using an ambulatory multichannel programmable pump. High antitumor effectiveness against metastatic colorectal cancer, Cancer, 69, 893, 10.1002/1097-0142(19920215)69:4<893::AID-CNCR2820690410>3.0.CO;2-X

Giacchetti, 1999, Chronomodulated CPT-11: a pilot study, Proc Am Soc Clin Oncol, 18, 259a

Diasio, 1989, Clinical pharmacology of 5-fluorouracil, Clin Pharmacokinet, 16, 215, 10.2165/00003088-198916040-00002

Lévi, 2000, Oxaliplatin. Pharmacokinetics and chronopharmacological aspects, Clinical Pharmacokinet, 36, 1

Garufi, 1997, A Phase I trial of five day chronomodulated infusion of 5-fluorouracil and l-folinic acid in patients with metastatic colorectal cancer, Eur J Cancer, 33, 1566, 10.1016/S0959-8049(97)00133-0

Lévi, 1997, for the International Organization for Cancer Chronotherapy: randomized multicentre trial of chronotherapy with oxaliplatin, fluorouracil, and folinic acid in metastatic colorectal cancer, Lancet, 350, 681, 10.1016/S0140-6736(97)03358-8

Lévi, 1999, for the International Organization for Cancer Chronotherapy: A multicentre evaluation of intensified ambulatory chronomodulated chemotherapy with oxaliplatin, fluorouracil and leucovorin as initial treatment of patients with metastatic colorectal cancer, Cancer, 85, 2532, 10.1002/(SICI)1097-0142(19990615)85:12<2532::AID-CNCR7>3.0.CO;2-1

Giacchetti, 2000, International Organization of Cancer: phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil – leucovorin as first line treatment of metastatic colorectal cancer, J Clin Oncol, 18, 136, 10.1200/JCO.2000.18.1.136

Curé H, Pezet D, Kwiatkowski F, et al. 5-fluorouracil (5-FU) and l-folinic acid (l-FA) pharmacokinetics during chronomodulated (CM) delivery. International Conference on Chemotherapeutic Strategies for Treatment of Colorectal Cancer. Amsterdam, February 10–12, 1999.

Jolivet, 1998, Colorectal cancer chronotherapy: implementation in general hospitals and clinical results. Biological clocks: mechanisms and applications, 1152, 483

Bertheault-Cvitkovic, 1996, Biweekly intensified ambulatory chronomodulated chemotherapy with oxaliplatin, 5-fluorouracil and leucovorin in patients with metastatic colorectal cancer, J Clin Oncol, 14, 2950, 10.1200/JCO.1996.14.11.2950

Giacchetti, 1999, Long term survival of patients with unresectable colorectal liver metastases following infusional chemotherapy with 5-fluorouracil, folinic acid, oxaliplatin and surgery, Ann Oncol, 10, 1, 10.1023/A:1008347829017

Lévi, 2000, International Organization for Cancer Chronotherapy: final efficacy update at 7 years of flat vs chronomodulated infusion (chrono) of oxaliplatin, 5-fluorouracil and leucovorin as first line treatment of metastatic colorectal cancer, Proc Am Soc Clin Oncol, 19, 242a

Stangl, 1994, Factors influencing the natural history of colorectal liver metastases, Lancet, 343, 1405, 10.1016/S0140-6736(94)92529-1

Mormont, 2000, Marked 24-h rest-activity rhythms are associated with better quality of life, better response and longer survival in patients with metastatic colorectal cancer and good performance status, Clin Cancer Res, 6, 3038

Sephton, 2000, Diurnal cortisol rhythm as a predictor of breast cancer survival, J Natl Cancer Inst, 92, 994, 10.1093/jnci/92.12.994

Ticher, 1996, The pattern of hormonal circadian time structure (acrophase) as an assessor of bresat-cancer risk, Int J Cancer, 65, 591, 10.1002/(SICI)1097-0215(19960301)65:5<591::AID-IJC6>3.0.CO;2-Y

Rafnsson, 2000, Incidence of cancer among commercial airline pilots, Occup Environ Med, 57, 175, 10.1136/oem.57.3.175

Ballard, 2000, Cancer incidence and mortality among flight personnel: a meta-analysis, Aviat Space Environ Med, 71, 216

Shah, 1984, Effect of melatonin on mammary carcinogenesis in intact and pinealectomized rats in varying photoperiods, Cancer Res, 44, 3403

van den Heiligenberg, 1999, Promoting effect of constant light exposure on diethylnitrosamine-induced hepatocarcinogenesis in rats, Life Sciences, 64, 2523, 10.1016/S0024-3205(99)00210-6

Buyse, 2000, Meta-Analysis Group in Cancer. Relation between tumour response to first-line chemotherapy and survival in advanced colorectal cancer: a meta-analysis, Lancet, 356, 373, 10.1016/S0140-6736(00)02528-9

Rivard, 1985, Maintenance chemotherapy for childhood acute lymphoblastic leukemia: better in the evening, Lancet, 2, 1264, 10.1016/S0140-6736(85)91551-X

Schmiegelow, 1997, Impact of morning versus evening schedule for oral methotrexate and 6-mercaptopurine on relapse risk for children with acute lymphoblastic leukemia, J Pediatr Hematol Oncol, 19, 102, 10.1097/00043426-199703000-00002

Bjarnason, 2000, Circadian variation of cell proliferation and cell protein expression in man: clinical implications, vol 4, 193

Lévi, 1994, Chronobiology of the immune system. Implication for the delivery of therapeutic agents, Clin Immunother, 2, 53, 10.1007/BF03258522

Lévi, 1995, A phase I–II trial of a five-day continuous intravenous infusion of 5-fluorouracil delivered at circadian rhythm modulated rate in patients with metastatic colorectal cancer, J Infus Chemother, 5, 153

Caussanel, 1990, Phase I trial of 5-day continuous venous infusion of oxaliplatin at circadian rhythm-modulated rate compared with constant rate, J Natl Cancer Inst, 82, 1046, 10.1093/jnci/82.12.1046