Expression of the human complement C8 subunits is independently regulated by interleukin 1β, interleukin 6, and interferon γ

Immunopharmacology - Tập 38 - Trang 167-175 - 1997
Beate Scheurer1, Christian Rittner1, Peter M. Schneider1
1Institute of Legal Medicine, Johannes Gutenberg University, Mainz, Germany

Tài liệu tham khảo

Baumann, 1990, Regulation of hepatic acute phase plasma protein genes by hepatocyte stimulating factors and other mediators of inflammation, Mol. Biol. Med., 7, 147 Baumann, 1994, The acute phase response, Immunol. Today, 15, 74, 10.1016/0167-5699(94)90137-6 Densen, 1988, Differential functional expression of the C8 subunits, 141, 2674 Goldberger, 1987, Transcriptional regulation of genes encoding the acute phase proteins CRP, SAA, and C3, J. Immunol., 138, 3967, 10.4049/jimmunol.138.11.3967 Hobart, 1995, Structure of the human C7 gene and comparison with the C6, C8A, C8B and C9 genes, J. Immunol., 154, 5188, 10.4049/jimmunol.154.10.5188 Kaufman, 1989, Chromosomal assignment of genes encoding the alpha, beta, and gamma subunits of human complement protein C8: identification of a close physical linkage between the alpha and the beta loci, Genomics, 5, 475, 10.1016/0888-7543(89)90012-8 Kaufmann, 1993, The human complement component C8B gene: structure and phylogenetic relationship, Hum. Genet., 92, 69, 10.1007/BF00216147 Lappin, 1990, Modulation by interferons of the expression of monocyte complement genes, Biochem. J., 268, 387, 10.1042/bj2680387 Letson, 1996, In vitro expression of the beta subunit of human complement component C8, Mol. Immunol., 33, 1295, 10.1016/S0161-5890(96)00108-3 Michelotti, 1995, Genomic organization of human complement protein C8α and further examination of ist linkage to C8β, Hum. Genet., 95, 513, 10.1007/BF00223862 Monahan, 1980, Binding of the eighth component of human complement to the soluble cytolytic complex is mediated by its beta subunit, J. Biol. Chem., 255, 10579, 10.1016/S0021-9258(19)70344-5 Monahan, 1983, Studies of the association of the eighth and ninth components of human complement within the membrane-bound cytolytic complex, J. Biol. Chem., 258, 5056, 10.1016/S0021-9258(18)32537-7 Morris, 1982, Complement biosynthesis by the human hepatoma-derived cell line HepG2, J. Clin. Invest., 70, 906, 10.1172/JCI110687 Ng, 1987, The eighth component of human complement: evidence that it is an oligomeric serum protein assembled from products of three different genes, Biochemistry, 26, 5229, 10.1021/bi00391a003 Ng, 1987, Biosynthesis of C8 by hepatocytes, 139, 3021 Nürnberger, 1990, Identification of the heterozygotes for deficiency of the beta-subunit of the eighth component of complement by reduced levels of C8 beta and increased amounts of free C8 alpha-gamma, Pediatr. Res., 27, 234, 10.1203/00006450-199003000-00006 Perissutti, 1994, Effect of cytokines on the secretion of the fifth and eighth complement components by HepG2 cells, Int. J. Clin. Lab. Res., 24, 45, 10.1007/BF02592409 Rittner, 1986, Human C81(α-γ) polymorphism: Detection in the α-γ subunit on SDS-PAGE, formal genetics and linkage relationship, Am. J. Hum. Genet., 38, 482 Roberts, 1973, Efficient translation of tobacco mosaic virus RNA and rabbit globin 9S RNA in a cell-free system from commercial wheat germ, 70, 2330 Sodetz, 1988, Structure and function of C8 in the membrane attack sequence of complement, Curr. Top. Microbiol. Immunol., 140, 19, 10.1007/978-3-642-73911-8_3 Späth, 1995, Expression of the complement C8 genes during interleukin-6-mediated in vitro induction of the acute-phase response, Exp. Clin. Immunogenet., 12, 53 Steel, 1994, The major acute phase reactants: C-reactive protein, serum amyloid P component and serum amyloid A protein, Immunol. Today, 15, 81, 10.1016/0167-5699(94)90138-4 Strunk, 1985, Pretranslational regulation of the synthesis of the third component of complement in human mononuclear phagocytes by the lipid A portion og lipopolysaccharide, J. Clin. Invest., 76, 985, 10.1172/JCI112099 Tedesco, 1990, Two distinct abnormalities in patients with C8 alpha-gamma deficiency, 86, 884 Thériault, 1992, Regional chromosomal assignment of genes encoding the alpha and beta subunits of human complement protein C8 to lp32, Hum. Genet., 88, 703, 10.1007/BF02265304