Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 Mortality
Tomer Zohar1,2, Carolin Loos1,2, Stephanie Fischinger1,3, Caroline Atyeo1,4, Chuangqi Wang2, Matthew D. Slein1, John Burke1, Jingyou Yu5, Jared Feldman1, Blake Marie Hauser1, Tim Caradonna1, Aaron G. Schmidt1, Yongfei Cai6, Hendrik Streeck7, Edward T. Ryan8, Dan H. Barouch5, Richelle C. Charles8, Douglas A. Lauffenburger2, Galit Alter1
1Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA
2Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA
3PhD Program in Immunology and Virology, University of Duisburg-Essen, Essen, Germany
4PhD Program in Virology, Division of Medical Sciences, Harvard University, Boston, MA, USA
5Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
6Division of Molecular Medicine, Boston Children’s Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA, USA
7Institute of Virology, University Hospital, University of Bonn and German Center for Infection Research (DZIF), Bonn-Cologne, Bonn, Germany
8Infectious Disease Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA