Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases

Cell - Tập 159 - Trang 1603-1614 - 2014
Tomoyuki Mashimo1,2,3, Kumar Pichumani4, Vamsidhara Vemireddy1,2,3, Kimmo J. Hatanpaa2,3,5, Dinesh Kumar Singh2,3,6, Shyam Sirasanagandla1,2,3, Suraj Nannepaga2,3,6, Sara G. Piccirillo3,6, Zoltan Kovacs4, Chan Foong5, Zhiguang Huang7, Samuel Barnett8, Bruce E. Mickey2,3,8, Ralph J. DeBerardinis2,9,10, Benjamin P. Tu7, Elizabeth A. Maher1,2,3,6, Robert M. Bachoo1,2,3,6
1Department of Internal Medicine, UT Southwestern Medical Center, Dallas TX, 75390, USA
2Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX 75390, USA
3Annette G. Strauss Center for Neuro-Oncology, UT Southwestern Medical Center, Dallas, TX 75390, USA
4Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX 75390, USA
5Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75390, USA
6Department of Neurology and Neurotherapeutics, UT Southwestern Medical Center, Dallas, TX, 75390, USA
7Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX 75390, USA
8Department of Neurological Surgery, UT Southwestern Medical Center, Dallas, TX 75390, USA
9McDermott Center for Human Growth and Development, UT Southwestern Medical Center, Dallas, TX 75390, USA
10Children’s Medical Center Research Institute, UT Southwestern Medical Center, Dallas, TX 75390, USA

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