Olive (Olea europaea L.) leaf extract attenuates early diabetic neuropathic pain through prevention of high glucose-induced apoptosis: In vitro and in vivo studies

Adriaensen, 2005, Critical review of oral drug treatments for diabetic neuropathic pain-clinical outcomes based on efficacy and safety data from placebo-controlled and direct comparative studies, Diabetes and Metabolism Research and Reviews, 21, 231, 10.1002/dmrr.552 Allen, 2005, Mechanisms of high glucose-induced apoptosis and its relationship to diabetic complications, Journal of Nutritional Biochemistry, 16, 705, 10.1016/j.jnutbio.2005.06.007 Amour, 1941, A method of determining loss of pain sensation, Journal of Pharmacology and Experimental Therapeutics, 27, 74 Bei, 2009, Neuroprotective effects of a standardized flavonoid extract from Diospyros kaki leaves, Journal of Ethnopharmacology, 126, 134, 10.1016/j.jep.2009.07.034 Benavente-Garcia, 2000, Antioxidant activity of phenolics extracted from Olea europea L. leaves, Food Chemistry, 68, 457, 10.1016/S0308-8146(99)00221-6 Bianco, 2000, Biophenolic components of olives, Food Research International, 33, 475, 10.1016/S0963-9969(00)00072-7 Blois, 1958, Antioxidant determination by use of a stable free radical, Nature, 181, 1199, 10.1038/1811199a0 Brownlee, 2001, Biochemistry and molecular cell biology of diabetic complications, Nature, 414, 813, 10.1038/414813a Chandrasekaran, 2010, Apoptosis in HepG2 cells exposed to high glucose, Toxicology in Vitro, 24, 387, 10.1016/j.tiv.2009.10.020 Chopra, 2010, Sesamol suppresses neuro-inflammatory cascade in experimental model of diabetic neuropathy, Journal of Pain, 11, 950, 10.1016/j.jpain.2010.01.006 Dekanski, 2009, Attenuation of cold restraint stress-induced gastric lesions by an olive leaf extract, General Physiology and Biophysics, 28, 135 Denizot, 1986, Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability, Journal of Immunological Methods, 89, 271, 10.1016/0022-1759(86)90368-6 Dyck, 2000, Patterns of quantitative sensation testing of hypoesthesia and hyperalgesia are predictive of diabetic polyneuropathy: a study of three cohorts. Nerve growth factor study group, Diabetes Care, 23, 510, 10.2337/diacare.23.4.510 Edwards, 2008, Diabetic neuropathy: mechanisms to management, Pharmacology and Therapeutics, 120, 1, 10.1016/j.pharmthera.2008.05.005 El, 2009, Olive tree (Olea europaea) leaves: potential beneficial effects on human health, Nutrition Review, 67, 632, 10.1111/j.1753-4887.2009.00248.x Esmaeili-Mahani, 2007, Nifedipine suppresses morphine-induced thermal hyperalgesia: evidence for the role of corticosterone, European Journal of Pharmacology, 567, 95, 10.1016/j.ejphar.2007.03.042 Esmaeili-Mahani, 2008, Low-dose morphine induces hyperalgesia through activation of Gαs, protein kinase C, and L-type Ca2+ channels in rats, Journal of Neuroscience Research, 86, 471, 10.1002/jnr.21489 Esmaeili-Mahani, 2010, Olive (Olea europaea L.) leaf extract elicits antinociceptive activity potentiates morphine analgesia and suppresses morphine hyperalgesia in rats, Journal of Ethnopharmacology, 132, 200, 10.1016/j.jep.2010.08.013 Freshwater, 2002, Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats, Diabetes, 51, 2249, 10.2337/diabetes.51.7.2249 Gong, 2009, Effects of hydroxytyrosol-20 on carrageenan-induced acute inflammation and hyperalgesia in rats, Phytotherapy Research, 23, 646, 10.1002/ptr.2686 Hajializadeh, 2010, Changes in the gene expression of specific G-protein subunits correlate with morphine insensitivity in streptozotocin-induced diabetic rats, Neuropeptides, 44, 299, 10.1016/j.npep.2010.02.004 Ilnytska, 2006, Poly(ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy, Diabetes, 55, 1686, 10.2337/db06-0067 Ji, 2008, Multipotent natural agents to combat Alzheimer's disease functional spectrum and structural features, Acta Pharmacologica Sinica, 29, 143, 10.1111/j.1745-7254.2008.00752.x Joseph, 2004, Caspase signalling in neuropathic and inflammatory pain in the rat, European Journal of Neuroscience, 20, 2896, 10.1111/j.1460-9568.2004.03750.x Kamboj, 2010, N-acetylcysteine inhibits hyperglycemia-induced oxidative stress and apoptosis markers in diabetic neuropathy, Journal of Neurochemistry, 112, 77, 10.1111/j.1471-4159.2009.06435.x Kamenov, 2006, Physiological characteristics of diabetic neuropathy in sucrose-fed Otsuka Long-Evans Tokushima fatty rats, Methods Find Experimental and Clinical Pharmacology, 28, 13, 10.1358/mf.2006.28.1.962772 Kumar, 2005, Effects of adenosine and adenosine A2A receptor agonist on motor nerve conduction velocity and nerve blood flow in experimental diabetic neuropathy, Neurolological Research, 27, 60, 10.1179/016164105X18278 Lee, 2010, Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract, Bioresource Technology, 101, 3751, 10.1016/j.biortech.2009.12.052 Lee, 2009, Assessment of phenolics-enriched extract and fractions of olive leaves and their antioxidant activities, Bioresource Technology, 100, 6107, 10.1016/j.biortech.2009.06.059 Lelkes, 2001, Reactive oxygen species, apoptosis and altered NGF-induced signaling in PC12 pheochromocytoma cells cultured in elevated glucose: an in vitro cellular model for diabetic neuropathy, Neurotoxicology Research, 3, 189, 10.1007/BF03033191 Mohagheghi, 2011, The neuroprotective effect of olive leaf extract is related to improved blood–brain barrier permeability and brain edema in rat with experimental focal cerebral ischemia, Phytomedicine, 15, 170, 10.1016/j.phymed.2010.06.007 Omagari, 2010, Olive leaf extract prevents spontaneous occurrence of non-alcoholic steatohepatitis in SHR/NDmcr-cp rats, Pathology, 42, 66, 10.3109/00313020903434389 Pazdro, 2010, The role of vitamin E and oxidative stress in diabetes complications, Mechanisms of Ageing and development, 131, 276, 10.1016/j.mad.2010.03.005 Piga, 2010, Protective effect of serotonin derivatives on glucose-induced damage rat pheochromocytoma cells, British Journal of Nutrition, 103, 25, 10.1017/S0007114509991486 Russell, 1999, Neurons undergo apoptosis in animal and cell culture models of diabetes, Neurobiology of Disease, 6, 347, 10.1006/nbdi.1999.0254 Russell, 2002, High glucose-induced oxidative stress and mitochondrial dysfunction in neurons, FASEB Journal, 16, 1738, 10.1096/fj.01-1027com Sekiguchi, 2009, Comparison of neuropathic pain and neuronal apoptosis following nerve root or spinal nerve compression, European Spine Journal, 18, 1978, 10.1007/s00586-009-1064-z Sharifi, 2009, Involvement of caspase-8 -9, and -3 in high glucose-induced apoptosis in PC12 cells, Neuroscience Letter, 459, 47, 10.1016/j.neulet.2009.03.100 Tesfaye, 2007, Factors that impact symptomatic diabetic peripheral neuropathy in placebo-administered patients from two 1-year clinical trials, Diabetes Care, 30, 2626, 10.2337/dc07-0608 Tomlinson, 2008, Glucose neurotoxicity, Nature Review of Neuroscience, 9, 36, 10.1038/nrn2294 Vincent, 2005, Short-term hyperglycemia produces oxidative damage and apoptosis in neurons, FASEB Journal, 959, 368 Vincent, 2007, SOD2 protects neurons from injury in cell culture and animal models of diabetic neuropathy, Experimental Neurology, 208, 216, 10.1016/j.expneurol.2007.07.017 Vincent, 2008, The antioxidant response as a drug target in diabetic neuropathy, Current Drug Targets, 9, 94, 10.2174/138945008783431754 Yokozawa, 2007, Protective effect of persimmon peel polyphenol against high glucose-induced oxidative stress in LLC-PK1 cells, Food and Chemical Toxicology, 45, 1979, 10.1016/j.fct.2007.04.018 Zimmermann, 1983, Ethical guidelines for investigations of experimental pain in conscious animals, Pain, 16, 109, 10.1016/0304-3959(83)90201-4 Zochodne, 2008, Diabetic polyneuropathy: an update, Current Opinion in Neurology, 21, 527, 10.1097/WCO.0b013e32830b84cb