Ouabain inhibits the increase due to palytoxin of cation permeability of erythrocytes
Naunyn-Schmiedebergs Archiv für Pharmakologie und experimentelle Pathologie - Tập 319 - Trang 101-107 - 1982
Tóm tắt
We assume that the formation of nonspecific pores by palytoxin is linked with its surface activity. Further experiments should demonstrate whether ouabain prevents the binding of palytoxin to erythrocytes (“receptor hypothesis”), or whether an ouabain-sensitive hydrolysis of trace amounts of ATP (“metabolic hypothesis”) promotes the palytoxin effect.
Tài liệu tham khảo
Beaugé CA, del Campillo E (1976) The ATP dependence of a ouabain-sensitive sodium efflux activated by external sodium, potassium and lithium in human red cells. Biochim Biophys Acta 433:547–554
Bernstein RE (1954) Potassium and sodium balance in mammalian red cells. Science 120:459–460
Chan PC, Calabrese V, Theil LS (1964) Species differences in the effect of sodium and potassium ions on the ATPase of erythrocyte membranes. Biochim Biophys Acta 79:424–426
Chhatwal GS, Ahnert-Hilger G, Beress L, Habermann E (1982) Palytoxin both induces and inhibits the release of histamine from rat mast cells. Int Archs Allergy Appl Immun 68:97–100
Dodge JT, Mitchell C, Hanahan DJ (1963) The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes. Arch Biochem 100:119–130
Eisner DA, Richards DE (1981) The interaction of potassium ions and ATP on the sodium pump of resealed red cell ghosts. J Physiol 319:403–418
Erdmann E, Hasse W (1975) Quantitative aspects of ouabain binding to human erythrocyte and cardiae membranes. J Physiol 251:671–682
Erdmann E, Schoner W (1973) Ouabain-receptor interactions in (Na+ +K+)-ATPase preparation from different tissues and species. Determination of kinetic constants and dissociation constants. Biochim Biophys Acta 307:386–398
Habermann E, Beress L (1979) Iodine labelling of sea anemone toxin II, and binding to normal and denervated diaphragm. Naunyn-Schmiedeberg's Arch Pharmacol 309:165–170
Habermann E, Ahnert-Hilger G, Chhatwal GS, Beress L (1981a) Delayed haemolytic action of palytoxin. General characteristics. Biochim Biophys Acta 649:481–486
Habermann E, Chhatwal GS, Hessler HJ (1981b) Palytoxin raises the nonspecific permeability of erythrocytes in an ouabain-sensitive manner. Naunyn-Schmiedeberg's Arch Pharmacol 317:P374
Horwitt BN (1952) Determination of inorganic serum phosphate by means of stannous chloride. J Biol Chem 199:537–541
Moore RE, Bartolini G (1981) Structure of palytoxin. J Am Chem Soc 103:2491–2494
Moore RE, Scheuer PJ (1971) Palytoxin: A new marine toxin from a coelenterate. Science 172:495–498
Ponder E (1948) Hemolysis and related phenomena. Grune and Stratton, New York
Uemura D, Neda K, Hirata Y (1981) Further studies on palytoxin. Tetrahedron Lett 22:2781–2784
Walz FG, Chan PC (1966) Adenosine triphosphate dependent retention of sodium ions by a sodium and potassium-activated adenosine triphosphate preparation from erythrocyte membranes. Arch Biochem 113:569–574
Whittam R (1958) Potassium movements and ATP in human red cells. J Physiol (London) 140:479–497