Microglial changes occur without neural cell death in diabetic retinopathy

Vision Research - Tập 47 - Trang 612-623 - 2007
David Gaucher1,2,3, Jean-Armand Chiappore1,2, Michel Pâques1,2,4, Manuel Simonutti1,2, Christian Boitard5, José A. Sahel1,2,4,6, Pascale Massin3, Serge Picaud1,2,4
1INSERM U-592, Hôpital St. Antoine, Laboratoire de Physiopathologie Cellulaire et Moléculaire de la Rétine, Bâtiment Kourilsky, 184 rue du Faubourg Saint-Antoine, 755751 Paris Cedex 12, France
2Université Pierre Et Marie Curie-Paris 6, Paris, France
3Assistance Publique-Hôpitaux de Paris, Hôpital Lariboisière, Service d’Ophtalmologie, Université Paris 7, Paris, France
4Fondation Ophtalmologique Adolphe de Rothschild, Paris, France
5INSERM U-561, Hôpital St. Vincent de Paul, Paris, France
6Centre Hospitalier National d’Ophtalmologie des Quinze-Vingts, Paris, France

Tài liệu tham khảo

Abu-El-Asrar, 2004, Expression of apoptosis markers in the retinas of human subjects with diabetes, Investigative Ophthalmology and Visual Science, 45, 2760, 10.1167/iovs.03-1392 Agardh, 2001, Retinal glial cell immunoreactivity and neuronal cell changes in rats with STZ-induced diabetes, Current Eye Research, 23, 276, 10.1076/ceyr.23.4.276.5459 Asnaghi, 2003, A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat, Diabetes, 52, 506, 10.2337/diabetes.52.2.506 Barber, 2005, The Ins2Akita mouse as a model of early retinal complications in diabetes, Investigative Ophthalmology and Visual Science, 46, 2210, 10.1167/iovs.04-1340 Barber, 1998, Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin, Journal of Clinical Investigation, 102, 783, 10.1172/JCI2425 Bresnick, 1987, Temporal aspects of the electroretinogram in diabetic retinopathy, Archives of Ophthalmology, 105, 660, 10.1001/archopht.1987.01060050078042 Caputo, 1990, Evidence for early impairment of macular function with pattern ERG in type I diabetic patients, Diabetes Care, 13, 412, 10.2337/diacare.13.4.412 Ciulla, 2003, Diabetic retinopathy and diabetic macular edema: pathophysiology, screening, and novel therapies, Diabetes Care, 26, 2653, 10.2337/diacare.26.9.2653 Davis, 1992, Diabetic retinopathy. A clinical overview, Diabetes Care, 15, 1844, 10.2337/diacare.15.12.1844 Diani, 1987, The KKAy mouse: a model for the rapid development of glomerular capillary basement membrane thickening, Blood Vessels, 24, 297 Ewing, 1998, Seeing beyond retinopathy in diabetes: electrophysiological and psychophysical abnormalities and alterations in vision, Endocrine Reviews, 19, 462, 10.1210/edrv.19.4.0340 Fortune, 1999, Multifocal electroretinogram delays reveal local retinal dysfunction in early diabetic retinopathy, Investigative Ophthalmology and Visual Science, 40, 2638 Hancock, 2004, Oscillatory potential analysis and ERGs of normal and diabetic rats, Investigative Ophthalmology and Visual Science, 45, 1002, 10.1167/iovs.03-1080 Hanitzsch, 2004, The effect of GABA and the GABA-uptake-blocker NO-711 on the b-wave of the ERG and the responses of horizontal cells to light, Graefe’s Archives for Clinical and Experimental Ophthalmology, 7, 7 Holopigian, 1992, A comparison of photopic and scotopic electroretinographic changes in early diabetic retinopathy, Investigative Ophthalmology and Visual Science, 33, 2773 Hotta, 1997, Electroretinogram in sucrose-fed diabetic rats treated with an aldose reductase inhibitor or an anticoagulant, American Journal of Physiology, 273, E965 Ishikawa, 1996, Accumulation of gamma-aminobutyric acid in diabetic rat retinal Müller cells evidenced by electron microscopic immunocytochemistry, Current Eye Research, 15, 958, 10.3109/02713689609017641 Ishikawa, 1996, Changes in GABA metabolism in streptozotocin-induced diabetic rat retinas, Current Eye Research, 15, 63, 10.3109/02713689609017612 Jung, 2000, Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion, Molecular and Cellular Biology, 20, 4106, 10.1128/MCB.20.11.4106-4114.2000 Krady, 2005, Minocycline reduces proinflammatory cytokine expression, microglial activation, and caspase-3 activation in a rodent model of diabetic retinopathy, Diabetes, 54, 1559, 10.2337/diabetes.54.5.1559 Lai, 2005, Generation of transgenic mice with mild and severe retinal neovascularisation, British Journal of Ophthalmology, 89, 911, 10.1136/bjo.2004.059089 Larger, 1995, Pancreatic islet beta cells drive T cell-immune responses in the nonobese diabetic mouse model, Journal of Experimental Medicine, 181, 1635, 10.1084/jem.181.5.1635 Lieth, 1998, Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy. Penn State Retina Research Group, Diabetes, 47, 815, 10.2337/diabetes.47.5.815 Li, 2002, Early retinal damage in experimental diabetes: electroretinographical and morphological observations, Experimental Eye Research, 74, 615, 10.1006/exer.2002.1170 Lowitt, 1993, Acetyl-l-carnitine corrects electroretinographic deficits in experimental diabetes, Diabetes, 42, 1115, 10.2337/diab.42.8.1115 Martin, 2004, Death of retinal neurons in streptozotocin-induced diabetic mice, Investigative Ophthalmology and Visual Science, 45, 3330, 10.1167/iovs.04-0247 Ning, 2004, Neuro-optic cell apoptosis and microangiopathy in KKAY mouse retina, International Journal of Molecular Medicine, 13, 87 Ou, 1993, Rapid analysis of hemoglobin variants by cation-exchange HPLC, Clinical Chemistry, 39, 820, 10.1093/clinchem/39.5.820 Park, 2003, Apoptotic death of photoreceptors in the streptozotocin-induced diabetic rat retina, Diabetologia, 46, 1260, 10.1007/s00125-003-1177-6 Raivich, 1999, Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function, Brain Research. Brain Research Reviews, 30, 77, 10.1016/S0165-0173(99)00007-7 Rakoczy, 2003, Enhanced recombinant adeno-associated virus-mediated vascular endothelial growth factor expression in the adult mouse retina: a potential model for diabetic retinopathy, Diabetes, 52, 857, 10.2337/diabetes.52.3.857 Ruberte, 2004, Increased ocular levels of IGF-1 in transgenic mice lead to diabetes-like eye disease, Journal of Clinical Investigation, 113, 1149, 10.1172/JCI19478 Rungger-Brandle, 2000, Glial reactivity, an early feature of diabetic retinopathy, Investigative Ophthalmology and Visual Science, 41, 1971 Sakai, 1995, Development of electroretinographic alterations in streptozotocin-induced diabetes in rats, Ophthalmic Research, 27, 57, 10.1159/000267571 Segawa, 1988, The development of electroretinogram abnormalities and the possible role of polyol pathway activity in diabetic hyperglycemia and galactosemia, Metabolism, 37, 454, 10.1016/0026-0495(88)90046-7 Shirao, 1998, Electrical responses from diabetic retina, Progress in Retinal Eye Research, 17, 59, 10.1016/S1350-9462(97)00005-0 Szkudelski, 2001, The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas, Physiological Research, 50, 537 Tzekov, 1999, The electroretinogram in diabetic retinopathy, Survey of Ophthalmology, 44, 53, 10.1016/S0039-6257(99)00063-6 Wachtmeister, 1998, Oscillatory potentials in the retina: what do they reveal, Progress in Retinal Eye Research, 17, 485, 10.1016/S1350-9462(98)00006-8 Wu, 2004, Insulin promotes rat retinal neuronal cell survival in a p70S6K-dependent manner, Journal of Biological Chemistry, 279, 9167, 10.1074/jbc.M312397200 Yamada, 2005, Retinal neovascularisation without ischaemia in the spontaneously diabetic Torii rat, Diabetologia, 48, 1663, 10.1007/s00125-005-1809-0 Yamamoto, 1996, Selective reduction of the S cone electroretinogram in diabetes, British Journal of Ophthalmology, 80, 973, 10.1136/bjo.80.11.973 Yoshida, 1991, Oscillatory potentials and permeability of the blood-retinal barrier in noninsulin-dependent diabetic patients without retinopathy, Ophthalmology, 98, 1266, 10.1016/S0161-6420(91)32144-4 Zeng, 2000, Neuronal and microglial response in the retina of streptozotocin-induced diabetic rats, Visual Neuroscience, 17, 463, 10.1017/S0952523800173122 Zhang, 2005, Genetic difference in susceptibility to the blood–retina barrier breakdown in diabetes and oxygen-induced retinopathy, American Journal of Pathology, 166, 313, 10.1016/S0002-9440(10)62255-9