Advanced oxidation process-mediated removal of pharmaceuticals from water: A review

Journal of Environmental Management - Tập 219 - Trang 189-207 - 2018
Devagi Kanakaraju1, Beverley D. Glass2, Michael Oelgemöller3
1Faculty of Resource Science and Technology, Universiti Malaysia Sarawak, 94300 Kota Samarahan, Sarawak, Malaysia
2Pharmacy, College of Medicine and Dentistry, James Cook University, Townsville, Qld 4811, Australia
3Discipline of Chemistry, College of Science and Engineering, James Cook University, Townsville, Qld 4811, Australia

Tài liệu tham khảo

Achilleos, 2010, UV-a and solar photodegradation of ibuprofen and carbamazepine catalyzed by TiO2, Sep. Sci. Technol., 45, 1564, 10.1080/01496395.2010.487463 Adityosulindro, 2017, Sonolysis and sono-Fenton oxidation for removal of ibuprofen in (waste)water, Ultrason. Sonochem., 39, 889, 10.1016/j.ultsonch.2017.06.008 Afonso-Olivares, 2017, Occurrence and environmental impact of pharmaceutical residues from conventional and natural wastewater treatment plants in Gran Canaria (Spain), Sci. Total. Environ., 599–600, 934, 10.1016/j.scitotenv.2017.05.058 Agüera, 2005, Application of time-of-flight mass spectrometry to the analysis of phototransformation products of diclofenac in water under natural sunlight, J. Mass. Spectrom., 40, 908, 10.1002/jms.867 Ahmed, 2017, Progress in the biological and chemical treatment technologies for emerging contaminant removal from wastewater: a critical review, J. Hazard. Mater., 323, 274, 10.1016/j.jhazmat.2016.04.045 Alalm, 2015, Degradation of four pharmaceuticals by solar photo-Fenton process: kinetics and costs estimation, J. Environ. Chem. Eng., 3, 46 Alharbi, 2016, Ozonation of carbamazepine, diclofenac, sulfamethoxazole and trimethoprim and formation of major oxidation products, Desalin. Water. Treat., 57, 29340, 10.1080/19443994.2016.1172986 Almomani, 2016, Removal of emerging pharmaceuticals from wastewater by ozone-based advanced oxidation processes, Environ. Prog. Sustain. Energy., 35, 982, 10.1002/ep.12306 Andreozzi, 1999, Advanced oxidation processes (AOP) for water purification and recovery, Catal. Today., 53, 51, 10.1016/S0920-5861(99)00102-9 Andreozzi, 2003, Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment, Chemosphere, 50, 1319, 10.1016/S0045-6535(02)00769-5 Andreozzi, 2005, Antibiotic removal from wastewaters: the ozonation of amoxicillin, J. Hazard. Mater., 122, 243, 10.1016/j.jhazmat.2005.03.004 Antonopoulou, 2016, Photocatalytic degradation kinetics, mechanism and ecotoxicity assessment of tramadol metabolites in aqueous TiO2 suspensions, Sci. Total. Environ., 545–546, 476, 10.1016/j.scitotenv.2015.12.088 Arlos, 2015, Distribution of selected antiandrogens and pharmaceuticals in a highly impacted watershed, Water. Res., 72, 40, 10.1016/j.watres.2014.11.008 Azuma, 2015, Occurrence and fate of selected anticancer, antimicrobial, and psychotropic pharmaceuticals in an urban river in a subcatchment of the Yodo River basin, Japan, Environ. Sci. Pollut. Res., 22, 18676, 10.1007/s11356-015-5013-6 Baena-Nogueras, 2017, Degradation kinetics of pharmaceuticals and personal care products in surface waters: photolysis vs biodegradation, Sci. Total. Environ., 590–591, 643, 10.1016/j.scitotenv.2017.03.015 Baeza, 2011, Transformation kinetics of biochemically active compounds in low-pressure UV photolysis and UV/H2O2 advanced oxidation processes, Water. Res., 45, 4531, 10.1016/j.watres.2011.05.039 Basha, 2011, On the adsorption/photodegradation of Amoxicillin in aqueous solutions by an integrated photocatalytic adsorbent (IPCA): experimental studies and kinetics analysis, Photochem. Photobiol. Sci., 10, 1014, 10.1039/c0pp00368a Bautista, 2008, An overview of the application of Fenton oxidation to industrial wastewaters treatment, J. Chem. Technol. Biotechnol., 83, 1323, 10.1002/jctb.1988 Bianchi, 2017, Aspirin and paracetamol removal using a commercial micro-sized TiO2 catalyst in deionized and tap water, Environ. Sci. Pollut. Res., 24, 12646, 10.1007/s11356-016-7781-z Biel-Maeso, 2018, Monitoring the occurrence of pharmaceuticals in soils irrigated with reclaimed wastewater, Environ. Pollut., 235, 312, 10.1016/j.envpol.2017.12.085 Blanco-Galvez, 2007, Solar photocatalytic detoxification and disinfection of water: recent overview, J. Sol. Energy. Eng. T. ASME., 129, 4, 10.1115/1.2390948 Borgatta, 2015, The anticancer drug metabolites endoxifen and 4-hydroxy-tamoxifen induce toxic effects on Daphnia pulex in a two-generation study, Sci. Total. Environ., 520, 232, 10.1016/j.scitotenv.2015.03.040 Bound, 2005, Household disposal of pharmaceuticals as a pathway for aquatic contamination in the United Kingdom, Environ. Health. Perspect., 113, 1705, 10.1289/ehp.8315 Brodin, 2013, Dilute concentrations of a psyschiatric drug alter behavior of fish from natural populations, Science, 339, 814, 10.1126/science.1226850 Brodin, 2014, Ecological effects of pharmaceuticals in aquatic systems—impacts through behavioural alterations, Philos. Trans. R. Soc. B Biol. Sci., 369, 10.1098/rstb.2013.0580 Cai, 2016, Effects of effluent organic matter (EfOM) on the removal of emerging contaminants by ozonation, Chemosphere, 151, 332, 10.1016/j.chemosphere.2016.02.094 Caliman, 2009, Pharmaceuticals, personal care products and endocrine disrupting agents in the environment - a review, Clean Soil. Air. Water., 37, 277, 10.1002/clen.200900038 Calza, 2006, Photocatalytic degradation study of diclofenac over aqueous TiO2 suspensions, Appl. Catal. B Environ., 67, 197, 10.1016/j.apcatb.2006.04.021 Candido, 2016, Ibuprofen removal by heterogeneous photocatalysis and ecotoxicological evaluation of the treated solutions, Environ. Sci. Pollut. Res., 23, 19911, 10.1007/s11356-016-6947-z Cao, 2013, Photocatalytic degradation kinetics and mechanism of phenobarbital in TiO2 aqueous solution, Chemosphere, 90, 1514, 10.1016/j.chemosphere.2012.07.066 Carabin, 2015, Photo-degradation of carbamazepine using TiO2 suspended photocatalysts, J. Taiwan. Inst. Chem. Eng., 54, 109, 10.1016/j.jtice.2015.03.006 Carbajo, 2016, Study of application of titania catalysts on solar photocatalysis: influence of type of pollutants and water matrices, Chem. Eng. J., 291, 64, 10.1016/j.cej.2016.01.092 Carballa, 2004, Behavior of pharmaceuticals, cosmetics and hormones in a sewage treatment plant, Water. Res., 38, 2918, 10.1016/j.watres.2004.03.029 Carbonaro, 2013, Continuous-flow photocatalytic treatment of pharmaceutical micropollutants: activity, inhibition, and deactivation of TiO2 photocatalysts in wastewater effluent, Appl. Catal. B Environ., 129, 1, 10.1016/j.apcatb.2012.09.014 Carmona, 2014, Occurrence of acidic pharmaceuticals and personal care products in Turia River Basin: from waste to drinking water, Sci. Total. Environ., 484, 53, 10.1016/j.scitotenv.2014.02.085 Carp, 2004, Photoinduced reactivity of titanium dioxide, Prog. Solid. State. Chem., 32, 33, 10.1016/j.progsolidstchem.2004.08.001 Causanilles, 2017, Occurrence and fate of illicit drugs and pharmaceuticals in wastewater from two wastewater treatment plants in Costa Rica, Sci. Total. Environ., 599–600, 98, 10.1016/j.scitotenv.2017.04.202 Dalrymple, 2007, Removing pharmaceuticals and endocrine-disrupting compounds from wastewater by photocatalysis, J. Chem. Technol. Biotechnol., 82, 121, 10.1002/jctb.1657 Dantas, 2011, Ozonation of propranolol: transformation, biodegradability, and toxicity assessment, J. Environ. Eng. ASCE, 137, 754, 10.1061/(ASCE)EE.1943-7870.0000377 Darwis, 2015, Radiation processing of polymers for medical and pharmaceutical applications, Macromol. Symp., 353, 15, 10.1002/masy.201550302 Das, 2014, Remediation of antiseptic components in wastewater by photocatalysis using TiO2 nanoparticles, Ind. Eng. Chem. Res., 53, 3012, 10.1021/ie403817z Davididou, 2017, Degradation and mineralization of antipyrine by UV-A LED photo-Fenton reaction intensified by ferrioxalate with addition of persulfate, Sep. Purif. Technol., 172, 227, 10.1016/j.seppur.2016.08.021 De Bel, 2011, Sonolysis of ciprofloxacin in aqueous solution: influence of operational parameters, Ultrason. Sonochem., 18, 184, 10.1016/j.ultsonch.2010.05.003 Deegan, 2011, Treatment options for wastewater effluents from pharmaceutical companies, Int. J. Environ. Sci. Technol., 8, 649, 10.1007/BF03326250 De la Cruz, 2013, Photolysis and TiO2 photocatalysis of the pharmaceutical propranolol: solar and artificial light, Appl. Catal. B Environ., 130, 249, 10.1016/j.apcatb.2012.10.003 De la Cruz, 2013, Degradation of emergent contaminants by UV, UV/H2O2 and neutral photo-Fenton at pilot scale in a domestic wastewater treatment plant, Water. Res., 47, 5836, 10.1016/j.watres.2013.07.005 de Lima Perini, 2013, Photo-Fenton degradation kinetics of low ciprofloxacin concentration using different iron sources and pH, J. Photochem. Photobiol. A Chem., 259, 53, 10.1016/j.jphotochem.2013.03.002 Destrieux, 2017, Drug residues in urban water: a database for ecotoxicological risk management, Sci. Total. Environ., 609, 927, 10.1016/j.scitotenv.2017.07.043 Dimitrakopoulou, 2012, Degradation, mineralization and antibiotic inactivation of amoxicillin by UV-A/TiO2 photocatalysis, J. Environ. Manag., 98, 168 Domenjoud, 2017, Innovative coupling of ozone oxidation and biodegradation for micropollutants removal from wastewater, Ozone Sci. Eng., 39, 296, 10.1080/01919512.2017.1350568 Donner, 2013, Ecotoxicity of carbamazepine and its UV photolysis transformation products, Sci. Total. Environ., 443, 870, 10.1016/j.scitotenv.2012.11.059 Drewes, 2002, Fate of pharmaceuticals during indirect potable reuse, Water. Sci. Technol., 46, 73, 10.2166/wst.2002.0058 Drillia, 2005, Fate and mobility of pharmaceuticals in solid matrices, Chemosphere, 60, 1034, 10.1016/j.chemosphere.2005.01.032 Drosos, 2015, The effect of NOM to TiO2: interactions and photocatalytic behavior, Appl. Catal. B Environ., 165, 328, 10.1016/j.apcatb.2014.10.017 Esplugas, 2007, Ozonation and advanced oxidation technologies to remove endocrine disrupting chemicals (EDCs) and pharmaceuticals and personal care products (PPCPs) in water effluents, J. Hazard. Mater., 149, 631, 10.1016/j.jhazmat.2007.07.073 Fatta-Kassinos, 2011, Pharmaceutical residues in environmental waters and wastewater: current state of knowledge and future research, Anal. Bioanal. Chem., 399, 251, 10.1007/s00216-010-4300-9 Fatta-Kassinos, 2011, Transformation products of pharmaceuticals in surface waters and wastewater formed during photolysis and advanced oxidation processes - degradation, elucidation of byproducts and assessment of their biological potency, Chemosphere, 85, 693, 10.1016/j.chemosphere.2011.06.082 Feng, 2013, Removal of residual anti-inflammatory and analgesic pharmaceuticals from aqueous systems by electrochemical advanced oxidation processes, A Rev. Chem. Eng. J., 228, 944, 10.1016/j.cej.2013.05.061 Ferrari, 2003, Ecotoxicological impact of pharmaceuticals found in treated wastewaters: study of carbamazepine, clofibric acid, and diclofenac, Ecotox. Environ. Safe., 55, 359, 10.1016/S0147-6513(02)00082-9 Friedmann, 2010, TiO2 for water treatment: parameters affecting the kinetics and mechanisms of photocatalysis, Appl. Catal. B Environ., 99, 398, 10.1016/j.apcatb.2010.05.014 Fukahori, 2012, Photocatalytic decomposition of crotamiton over aqueous TiO2 suspensions: determination of intermediates and the reaction pathway, Chemosphere, 89, 213, 10.1016/j.chemosphere.2012.04.018 García-Araya, 2010, Diclofenac removal from water by ozone and photolytic TiO2 catalysed processes, J. Chem. Technol. Biotechnol., 85, 798, 10.1002/jctb.2363 García-Espinoza, 2018, Electrochemical carbamazepine degradation: effect of the generated active chlorine, transformation pathways and toxicity, Chemosphere, 192, 142, 10.1016/j.chemosphere.2017.10.147 Garcia-Segura, 2018, Electrochemical oxidation remediation of real wastewater effluents - a review, Process. Saf. Environ. Prot., 113, 48, 10.1016/j.psep.2017.09.014 Ghafoori, 2015, Sonophotolytic degradation of synthetic pharmaceutical wastewater: statistical experimental design and modeling, J. Environ. Manag., 150, 128 Giraldo, 2010, Degradation of the antibiotic oxolinic acid by photocatalysis with TiO2 in suspension, Water. Res., 44, 5158, 10.1016/j.watres.2010.05.011 Giraldo-Aguirre, 2017, Removal of â-lactam antibiotics from pharmaceutical wastewaters using photo-Fenton process at near-neutral pH, Environ. Sci. Pollut. Res., 1 Gogate, 2004, A review of imperative technologies for wastewater treatment I: oxidation technologies at ambient conditions, Adv. Environ. Res., 8, 501, 10.1016/S1093-0191(03)00032-7 Grabicova, 2017, Bioaccumulation of psychoactive pharmaceuticals in fish in an effluent dominated stream, Water. Res., 124, 654, 10.1016/j.watres.2017.08.018 Gros, 2017, Screening and prioritization of micropollutants in wastewaters from on-site sewage treatment facilities, J. Hazard. Mater., 328, 37, 10.1016/j.jhazmat.2016.12.055 Guerra, 2014, Occurrence and fate of antibiotic, analgesic/anti-inflammatory, and antifungal compounds in five wastewater treatment processes, Sci. Total. Environ., 473–474, 235, 10.1016/j.scitotenv.2013.12.008 Guo, 2018, Behavior of antibiotic resistance genes under extremely high-level antibiotic selection pressures in pharmaceutical wastewater treatment plants, Sci. Total. Environ., 612, 119, 10.1016/j.scitotenv.2017.08.229 Guyer, 2011, Degradation of diclofenac in water by homogeneous and heterogeneous sonolysis, Ultrason. Sonochem., 18, 114, 10.1016/j.ultsonch.2010.03.008 Haroune, 2014, Photocatalytic degradation of carbamazepine and three derivatives using TiO2 and ZnO: effect of pH, ionic strength, and natural organic matter, Sci. Total. Environ., 475, 16, 10.1016/j.scitotenv.2013.12.104 Heberer, 2002, Tracking persistent pharmaceutical residues from municipal sewage to drinking water, J. Hydrol., 266, 175, 10.1016/S0022-1694(02)00165-8 Heberer, 2002, From municipal sewage to drinking water: fate and removal of pharmaceutical residues in the aquatic environment in urban areas, Water. Sci. Technol., 46, 81, 10.2166/wst.2002.0060 Hou, 2016, The occurrence and fate of tetracyclines in two pharmaceutical wastewater treatment plants of Northern China, Environ. Sci. Pollut. Res., 23, 1722, 10.1007/s11356-015-5431-5 Hu, 2016, Study on the kinetics and transformation products of salicylic acid in water via ozonation, Chemosphere, 153, 394, 10.1016/j.chemosphere.2016.03.074 Ikehata, 2006, Degradation of aqueous pharmaceuticals by ozonation and advanced oxidation processes: a review, Ozone Sci. Eng., 28, 353, 10.1080/01919510600985937 Ince, 2018, Ultrasound-assisted advanced oxidation processes for water decontamination, Ultrason. Sonochem., 40, 97, 10.1016/j.ultsonch.2017.04.009 Jallouli, 2018, Heterogeneous photocatalytic degradation of ibuprofen in ultrapure water, municipal and pharmaceutical industry wastewaters using a TiO2/UV-LED system, Chem. Eng. J., 334, 976, 10.1016/j.cej.2017.10.045 Ji, 2018, Photodegradation of sulfasalazine and its human metabolites in water by UV and UV/peroxydisulfate processes, Water. Res., 133, 299, 10.1016/j.watres.2018.01.047 Jiang, 2013, Occurrence, transportation, monitoring and treatment of emerging micro-pollutants in waste water - a review from global views, Microchem. J., 110, 292, 10.1016/j.microc.2013.04.014 Jones, 2005, Pharmaceuticals: a threat to drinking water?, Trends. Biotechnol., 23, 163, 10.1016/j.tibtech.2005.02.001 Jung, 2012, Removal of amoxicillin by UV and UV/H2O2 processes, Sci. Total. Environ., 420, 160, 10.1016/j.scitotenv.2011.12.011 Kanakaraju, 2014, Titanium dioxide photocatalysis for pharmaceutical wastewater treatment, Environ. Chem. Lett., 12, 27, 10.1007/s10311-013-0428-0 Kanakaraju, 2014, Photolysis and TiO2-catalysed degradation of diclofenac in surface and drinking water using circulating batch photoreactors, Environ. Chem., 11, 51, 10.1071/EN13098 Kanakaraju, 2015, TiO2 photocatalysis of naproxen: effect of the water matrix, anions and diclofenac on degradation rates, Chemosphere, 139, 579, 10.1016/j.chemosphere.2015.07.070 Kanakaraju, 2016, Solar photolysis versus TiO2-mediated solar photocatalysis: a kinetic study of the degradation of naproxen and diclofenac in various water matrices, Environ. Sci. Pollut. Res., 23, 17437, 10.1007/s11356-016-6906-8 Kanakaraju, 2017, Combined effects of adsorption and photocatalysis by hybrid TiO2/ZnO-calcium alginate beads for the removal of copper, J. Environ. Sci., 55, 214, 10.1016/j.jes.2016.05.043 Kaur, 2016, Heterogeneous photocatalytic studies of analgesic and non-steroidal anti-inflammatory drugs, Appl. Catal. A Gen., 510, 134, 10.1016/j.apcata.2015.11.008 Khetan, 2007, Human pharmaceuticals in the aquatic environment: a challenge to green chemistry, Chem. Rev., 107, 2319, 10.1021/cr020441w Kim, 2009, Performance of UV and UV/H2O2 processes for the removal of pharmaceuticals detected in secondary effluent of a sewage treatment plant in Japan, J. Hazard. Mater., 166, 1134, 10.1016/j.jhazmat.2008.12.020 Kim, 2017, Degradation of sulfamethoxazole by ionizing radiation: identification and characterization of radiolytic products, Chem. Eng. J., 313, 556, 10.1016/j.cej.2016.12.080 Klamerth, 2010, Modified photo-Fenton for degradation of emerging contaminants in municipal wastewater effluents, Catal. Today., 161, 241, 10.1016/j.cattod.2010.10.074 Klamerth, 2010, Degradation of fifteen emerging contaminants at μgL-1 initial concentrations by mild solar photo-Fenton in MWTP effluents, Water. Res., 44, 545, 10.1016/j.watres.2009.09.059 Klavarioti, 2009, Removal of residual pharmaceuticals from aqueous systems by advanced oxidation processes, Environ. Int., 35, 402, 10.1016/j.envint.2008.07.009 Kockler, 2012, Photochemical and photocatalytic degradation of diclofenac and amoxicillin using natural and simulated sunlight, J.Sustain. Sc. Manag., 7, 23 Koltsakidou, 2017, Photo-Fenton and Fenton-like processes for the treatment of the antineoplastic drug 5-fluorouracil under simulated solar radiation, Environ. Sci. Pollut. Res., 24, 4791, 10.1007/s11356-016-8138-3 Koroša, 2016, Determination of micro-organic contaminants in groundwater (Maribor, Slovenia), Sci. Total. Environ., 571, 1419, 10.1016/j.scitotenv.2016.06.103 Kümmerer, 2009, Antibiotics in the aquatic environment - a review - Part II, Chemosphere, 75, 435, 10.1016/j.chemosphere.2008.12.006 Kümmerer, 2009, The presence of pharmaceuticals in the environment due to human use - present knowledge and future challenges, J. Environ. Manag., 90, 2354 Kümmerer, 2000, Biodegradability of some antibiotics, elimination of the genotoxicity and affection of wastewater bacteria in a simple test, Chemosphere, 40, 701, 10.1016/S0045-6535(99)00439-7 Kuo, 2015, Photocatalytic degradation of methamphetamine by UV/TiO2-Kinetics, intermediates, and products, Water. Res., 74, 1, 10.1016/j.watres.2015.01.043 Kıdak, 2018, Medium-high frequency ultrasound and ozone based advanced oxidation for amoxicillin removal in water, Ultrason. Sonochem., 40, 131, 10.1016/j.ultsonch.2017.01.033 Lai, 2017, The role of bicarbonate anions in methotrexate degradation via UV/TiO2: mechanisms, reactivity and increased toxicity, Water. Res., 112, 157, 10.1016/j.watres.2017.01.040 Lambropoulou, 2008, Identification of photocatalytic degradation products of bezafibrate in TiO2 aqueous suspensions by liquid and gas chromatography, J. Chromatogr. A, 1183, 38, 10.1016/j.chroma.2007.12.030 Lambropoulou, 2017, Degradation of venlafaxine using TiO2/UV process: kinetic studies, RSM optimization, identification of transformation products and toxicity evaluation, J. Hazard. Mater., 323, 513, 10.1016/j.jhazmat.2016.04.074 Lapworth, 2012, Emerging organic contaminants in groundwater: a review of sources, fate and occurrence, Environ. Pollut., 163, 287, 10.1016/j.envpol.2011.12.034 Lee, 2017, Pharmaceutical residues in aquatic environment and water remediation by TiO2 heterogeneous photocatalysis: a review, Environ. Earth. Sci., 76, 611, 10.1007/s12665-017-6924-y Legrini, 1993, Photochemical processes for water-treatment, Chem. Rev., 93, 671, 10.1021/cr00018a003 Li, 2015, Electro-peroxone treatment of the antidepressant venlafaxine: operational parameters and mechanism, J. Hazard. Mater., 300, 298, 10.1016/j.jhazmat.2015.07.004 Li, 2017, Photodegradation kinetics, transformation, and toxicity prediction of ketoprofen, carprofen, and diclofenac acid in aqueous solutions, Environ. Toxicol. Chem., 36, 3232, 10.1002/etc.3915 Lianou, 2018, Sonochemical oxidation of piroxicam drug: effect of key operating parameters and degradation pathways, J. Chem. Technol. Biotechnol., 93, 28, 10.1002/jctb.5346 Lin, 2018, Mass loading and emission of thirty-seven pharmaceuticals in a typical municipal wastewater treatment plant in Hunan Province, Southern China, Ecotox. Environ. Safe., 147, 530, 10.1016/j.ecoenv.2017.08.052 Lindqvist, 2005, Occurrence of acidic pharmaceuticals in raw and treated sewages and in receiving waters, Water. Res., 39, 2219, 10.1016/j.watres.2005.04.003 Liu, 2016, Radiolysis of carbamazepine aqueous solution using electron beam irradiation combining with hydrogen peroxide: efficiency and mechanism, Chem. Eng. J., 295, 484, 10.1016/j.cej.2016.03.040 Lofrano, 2018, Municipal wastewater spiramycin removal by conventional treatments and heterogeneous photocatalysis, Sci. Total. Environ., 624, 461, 10.1016/j.scitotenv.2017.12.145 Loos, 2018, Electrochemical oxidation of key pharmaceuticals using a boron doped diamond electrode, Sep. Purif. Technol., 195, 184, 10.1016/j.seppur.2017.12.009 Lopez-Serna, 2013, Occurrence of 95 pharmaceuticals and transformation products in urban groundwaters underlying the metropolis of Barcelona, Spain, Environ. Pollut., 174, 305, 10.1016/j.envpol.2012.11.022 Luo, 2014, A review on the occurrence of micropollutants in the aquatic environment and their fate and removal during wastewater treatment, Sci. Total. Environ., 473–474, 619, 10.1016/j.scitotenv.2013.12.065 Luo, 2018, UV direct photolysis of sulfamethoxazole and ibuprofen: an experimental and modelling study, J. Hazard. Mater., 343, 132, 10.1016/j.jhazmat.2017.09.019 MacLeod, 2010, Loadings, trends, comparisons, and fate of achiral and chiral pharmaceuticals in wastewaters from urban tertiary and rural aerated lagoon treatments, Water. Res., 44, 533, 10.1016/j.watres.2009.09.056 Madhavan, 2010, Combined advanced oxidation processes for the synergistic degradation of ibuprofen in aqueous environments, J. Hazard. Mater., 178, 202, 10.1016/j.jhazmat.2010.01.064 Magureanu, 2015, Degradation of pharmaceutical compounds in water by non-thermal plasma treatment, Water. Res., 81, 124, 10.1016/j.watres.2015.05.037 Malato, 2002, Photocatalysis with solar energy at a pilot-plant scale: an overview, Appl. Catal. B Environ., 37, 1, 10.1016/S0926-3373(01)00315-0 Malato, 2009, Decontamination and disinfection of water by solar photocatalysis: recent overview and trends, Catal. Today., 147, 1, 10.1016/j.cattod.2009.06.018 Marcelino, 2017, Multistage ozone and biological treatment system for real wastewater containing antibiotics, J. Environ. Manag., 195, 110 Markic, 2018, Influence of process parameters on the effectiveness of photooxidative treatment of pharmaceuticals, J. Environ. Sci. Health. A. Tox. Hazard. Subst. Environ. Eng., 53, 338, 10.1080/10934529.2017.1401394 Márquez, 2014, Integration of ozone and solar TiO2-photocatalytic oxidation for the degradation of selected pharmaceutical compounds in water and wastewater, Sep. Purif. Technol., 136, 18, 10.1016/j.seppur.2014.08.024 Martínez-Alcalá, 2017, Pharmaceutical biological degradation, sorption and mass balance determination in a conventional activated-sludge wastewater treatment plant from Murcia, Spain, Chem. Eng. J., 316, 332, 10.1016/j.cej.2017.01.048 Méndez-Arriaga, 2008, Photocatalytic degradation of non-steroidal anti-inflammatory drugs with TiO2 and simulated solar irradiation, Water. Res., 42, 585, 10.1016/j.watres.2007.08.002 Méndez-Arriaga, 2008, Ultrasonic treatment of water contaminated with ibuprofen, Water. Res., 42, 4243, 10.1016/j.watres.2008.05.033 Méndez-Arriaga, 2009, Mineralization enhancement of a recalcitrant pharmaceutical pollutant in water by advanced oxidation hybrid processes, Water. Res., 43, 3984, 10.1016/j.watres.2009.06.059 Metcalfe, 2013, Pharmaceutical contaminants of emerging concern in the environment, Environ. Toxicol. Chem., 32, 1683, 10.1002/etc.2293 Michael, 2012, Solar photo-Fenton process on the abatement of antibiotics at a pilot scale: degradation kinetics, ecotoxicity and phytotoxicity assessment and removal of antibiotic resistant enterococci, Water. Res., 46, 5621, 10.1016/j.watres.2012.07.049 Michael, 2013, Urban wastewater treatment plants as hotspots for the release of antibiotics in the environment: a review, Water. Res., 47, 957, 10.1016/j.watres.2012.11.027 Miralles-Cuevas, 2014, Removal of pharmaceuticals from MWTP effluent by nanofiltration and solar photo-Fenton using two different iron complexes at neutral pH, Water. Res., 64, 23, 10.1016/j.watres.2014.06.032 Mirzaei, 2018, Occurrence and fate of most prescribed antibiotics in different water environments of Tehran, Iran, Sci. Total. Environ., 619–620, 446, 10.1016/j.scitotenv.2017.07.272 Moldovan, 2006, Occurrences of pharmaceutical and personal care products as micropollutants in rivers from Romania, Chemosphere, 64, 1808, 10.1016/j.chemosphere.2006.02.003 Mompelat, 2009, Occurrence and fate of pharmaceutical products and by-products, from resource to drinking water, Environ. Int., 35, 803, 10.1016/j.envint.2008.10.008 Moreira, 2015, Fast mineralization and detoxification of amoxicillin and diclofenac by photocatalytic ozonation and application to an urban wastewater, Water. Res., 87, 87, 10.1016/j.watres.2015.08.059 Naddeo, 2013, Sonochemical degradation of twenty-three emerging contaminants in urban wastewater, Desalin. Water. Treat., 51, 6601, 10.1080/19443994.2013.769696 Naddeo, 2015, Enhanced ozonation of selected pharmaceutical compounds by sonolysis, Environ. Technol. (United Kingdom)., 36, 1876 Nikolaou, 2007, Occurrence patterns of pharmaceuticals in water and wastewater environments, Anal. Bioanal. Chem., 387, 1225, 10.1007/s00216-006-1035-8 Oaks, 2004, Diclofenac residues as the cause of vulture population decline in Pakistan, Nature, 427, 630, 10.1038/nature02317 Oller, 2011, Combination of Advanced Oxidation Processes and biological treatments for wastewater decontamination-A review, Sci. Total. Environ., 409, 4141, 10.1016/j.scitotenv.2010.08.061 Paíga, 2016, Presence of pharmaceuticals in the Lis river (Portugal): sources, fate and seasonal variation, Sci. Total. Environ., 573, 164, 10.1016/j.scitotenv.2016.08.089 Pal, 2010, Impacts of emerging organic contaminants on freshwater resources: review of recent occurrences, sources, fate and effects, Sci. Total. Environ., 408, 6062, 10.1016/j.scitotenv.2010.09.026 Pan, 2014, Photocatalytic degradation of 17α-ethinylestradiol (EE2) in the presence of TiO2-doped zeolite, J. Hazard. Mater., 279, 17, 10.1016/j.jhazmat.2014.06.040 Pereira, 2014, Assessment of solar driven TiO2-assisted photocatalysis efficiency on amoxicillin degradation, Environ. Sci. Pollut. Res., 21, 1292, 10.1007/s11356-013-2014-1 Pérez, 2017, Treatment of real effluents from the pharmaceutical industry: a comparison between Fenton oxidation and conductive-diamond electro-oxidation, J. Environ. Manag., 195, 216 Perini, 2018, Simultaneous degradation of ciprofloxacin, amoxicillin, sulfathiazole and sulfamethazine, and disinfection of hospital effluent after biological treatment via photo-Fenton process under ultraviolet germicidal irradiation, Appl. Catal. B Environ., 224, 761, 10.1016/j.apcatb.2017.11.021 Perisic, 2016, Comparative analysis of UV-C/H2O2 and UV-A/TiO2 processes for the degradation of diclofenac in water, React. Kinet. Mech. Catal., 118, 451, 10.1007/s11144-016-1027-4 Rayaroth, 2016, Degradation of pharmaceuticals by ultrasound-based advanced oxidation process, Environ. Chem. Lett., 14, 259, 10.1007/s10311-016-0568-0 Reinholds, 2017, Decomposition of multi-class pharmaceutical residues in wastewater by exposure to ionising radiation, Int. J. Environ. Sci. Technol., 14, 1969, 10.1007/s13762-017-1290-6 Richardson, 2011, Water analysis: emerging contaminants and current issues, Anal. Chem., 83, 4614, 10.1021/ac200915r Rioja, 2016, Effect of water matrix on photocatalytic degradation and general kinetic modeling, Appl. Catal. B Environ., 180, 330, 10.1016/j.apcatb.2015.06.038 Rivas, 2012, Removal of emergent contaminants: integration of ozone and photocatalysis, J. Environ. Manag., 100, 10 Romero, 2011, Photocatalytic treatment of metoprolol and propranolol, Catal. Today., 161, 115, 10.1016/j.cattod.2010.09.026 Romero, 2015, Performance of different advanced oxidation technologies for the abatement of the beta-blocker metoprolol, Catal. Today, 240, 86, 10.1016/j.cattod.2014.03.060 Rosa Boleda, 2011, Evaluation of the presence of drugs of abuse in tap waters, Chemosphere, 84, 1601, 10.1016/j.chemosphere.2011.05.033 Salgado, 2012, Assessing the removal of pharmaceuticals and personal care products in a full-scale activated sludge plant, Environ. Sci. Pollut. Res., 19, 1818, 10.1007/s11356-011-0693-z Sangion, 2016, Hazard of pharmaceuticals for aquatic environment: prioritization by structural approaches and prediction of ecotoxicity, Environ. Int., 95, 131, 10.1016/j.envint.2016.08.008 Santos, 2010, Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment, J. Hazard. Mater., 175, 45, 10.1016/j.jhazmat.2009.10.100 Schneider, 2014, Understanding TiO2 photocatalysis: mechanisms and materials, Chem. Rev., 114, 9919, 10.1021/cr5001892 Schröder, 2016, Status of hormones and painkillers in wastewater effluents across several European states—considerations for the EU watch list concerning estradiols and diclofenac, Environ. Sci. Pollut. Res., 23, 12835, 10.1007/s11356-016-6503-x Sebestyén, 2018, Environmental risk assessment of human and veterinary medicinal products - challenges and ways of improvement, Microchem. J., 136, 67, 10.1016/j.microc.2017.08.012 Serna-Galvis, 2016, High frequency ultrasound as a selective advanced oxidation process to remove penicillinic antibiotics and eliminate its antimicrobial activity from water, Ultrason. Sonochem., 31, 276, 10.1016/j.ultsonch.2016.01.007 Silva, 2016, Degradation and acute toxicity removal of the antidepressant Fluoxetine (Prozac®) in aqueous systems by electron beam irradiation, Environ. Sci. Pollut. Res., 23, 11927, 10.1007/s11356-016-6410-1 Sires, 2012, Remediation of water pollution caused by pharmaceutical residues based on electrochemical separation and degradation technologies: a review, Environ. Int., 40, 212, 10.1016/j.envint.2011.07.012 Sirtori, 2010, Effect of water-matrix composition on Trimethoprim solar photodegradation kinetics and pathways, Water. Res., 44, 2735, 10.1016/j.watres.2010.02.006 Sirtori, 2011, Solar photo-Fenton degradation of nalidixic acid in waters and wastewaters of different composition. Analytical assessment by LC-TOF-MS, Water. Res., 45, 1736, 10.1016/j.watres.2010.11.023 Suárez, 2008, How are pharmaceutical and personal care products (PPCPs) removed from urban wastewaters?, Rev. Environ. Sci. Biotechnol., 7, 125, 10.1007/s11157-008-9130-2 Švorc, 2017, Advanced electrochemical platform for determination of cytostatic drug flutamide in various matrices using a boron-doped diamond electrode, Electrochim. Acta., 251, 621, 10.1016/j.electacta.2017.08.077 Szabó, 2018, Electron beam treatment for eliminating the antimicrobial activity of piperacillin in wastewater matrix, Ind. Eng. Chem. Res., 58, 24, 10.1016/j.jiec.2017.09.002 Tarpani, 2018, A methodology for estimating concentrations of pharmaceuticals and personal care products (PPCPs) in wastewater treatment plants and in freshwaters, Sci. Total. Environ., 622–623, 1417, 10.1016/j.scitotenv.2017.12.059 Ternes, 1998, Occurrence of drugs in German sewage treatment plants and rivers, Water. Res., 32, 3245, 10.1016/S0043-1354(98)00099-2 Ternes, 2002, Removal of pharmaceuticals during drinking water treatment, Environ. Sci. Technol., 36, 3855, 10.1021/es015757k Tran, 2018, Occurrence and fate of emerging contaminants in municipal wastewater treatment plants from different geographical regions-a review, Water. Res., 133, 182, 10.1016/j.watres.2017.12.029 Trawiński, 2017, Studies on photodegradation process of psychotropic drugs: a review, Environ. Sci. Pollut. Res., 24, 1152, 10.1007/s11356-016-7727-5 Trovó, 2011, Degradation of the antibiotic amoxicillin by photo-Fenton process - chemical and toxicological assessment, Water. Res., 45, 1394, 10.1016/j.watres.2010.10.029 Van Doorslaer, 2012, TiO2 mediated heterogeneous photocatalytic degradation of moxifloxacin: operational variables and scavenger study, Appl. Catal. B Environ., 111, 150, 10.1016/j.apcatb.2011.09.029 Van Doorslaer, 2015, Heterogeneous photocatalysis of moxifloxacin in hospital effluent: effect of selected matrix constituents, Chem. Eng. J., 261, 9, 10.1016/j.cej.2014.06.079 Veloutsou, 2014, Photo-Fenton decomposition of β-blockers atenolol and metoprolol; study and optimization of system parameters and identification of intermediates, Chemosphere, 107, 180, 10.1016/j.chemosphere.2013.12.031 Verlicchi, 2012, Occurrence of pharmaceutical compounds in urban wastewater: removal, mass load and environmental risk after a secondary treatment-A review, Sci. Total. Environ., 429, 123, 10.1016/j.scitotenv.2012.04.028 Villegas-Guzman, 2015, Evaluation of water matrix effects, experimental parameters, and the degradation pathway during the TiO2 photocatalytical treatment of the antibiotic dicloxacillin, J. Environ. Sci. Health. A. Tox. Hazard. Subst. Environ. Eng., 50, 40, 10.1080/10934529.2015.964606 Wang, 2017, Fe-based catalysts for heterogeneous catalytic ozonation of emerging contaminants in water and wastewater, Chem. Eng. J., 312, 79, 10.1016/j.cej.2016.11.118 Wang, 2016, Irradiation treatment of pharmaceutical and personal care products (PPCPs) in water and wastewater: an overview, Radiat. Phys. Chem., 125, 56, 10.1016/j.radphyschem.2016.03.012 Wang, 2016, Removal of pharmaceuticals and personal care products (PPCPs) from wastewater: a review, J. Environ. Manag., 182, 620 Wang, 2018, Degradation of carbamazepine by radiation-induced activation of peroxymonosulfate, Chem. Eng. J., 336, 595, 10.1016/j.cej.2017.12.068 Wang, 2012, Advanced oxidation processes for wastewater treatment: formation of hydroxyl radical and application, Crit. Rev. Environ. Sci. Technol., 42, 251, 10.1080/10643389.2010.507698 Wang, 2011, Degradation of tetracycline in aqueous media by ozonation in an internal loop-lift reactor, J. Hazard. Mater., 192, 35 Wang, 2018, Degradation of lincomycin in aqueous solution with hydrothermal treatment: kinetics, pathway, and toxicity evaluation, Chem. Eng. J., 343, 138, 10.1016/j.cej.2018.03.008 Xiang, 2018, The fate and risk assessment of psychiatric pharmaceuticals from psychiatric hospital effluent, Ecotox. Environ. Safe., 150, 289, 10.1016/j.ecoenv.2017.12.049 Yamamoto, 2009, Persistence and partitioning of eight selected pharmaceuticals in the aquatic environment: laboratory photolysis, biodegradation, and sorption experiments, Water. Res., 43, 351, 10.1016/j.watres.2008.10.039 Yang, 2017, Occurrences and removal of pharmaceuticals and personal care products (PPCPs) in drinking water and water/sewage treatment plants: a review, Sci. Total. Environ., 596–597, 303, 10.1016/j.scitotenv.2017.04.102 Yuan, 2009, Degradation of selected pharmaceuticals in aqueous solution with UV and UV/H2O2, Water. Res., 43, 1766, 10.1016/j.watres.2009.01.008 Zhao, 2017, Ozonation of indomethacin: kinetics, mechanisms and toxicity, J. Hazard. Mater., 323, 460, 10.1016/j.jhazmat.2016.05.023 Zheng, 2014, EB-radiolysis of carbamazepine: in pure-water with different ions and in surface water, J. Radioanal. Nucl. Chem., 302, 139, 10.1007/s10967-014-3322-8 Zhu, 2013, Photocatalytic degradation of tetracycline in aqueous solution by nanosized TiO2, Chemosphere, 92, 925, 10.1016/j.chemosphere.2013.02.066 Ziylan, 2011, The occurrence and fate of anti-inflammatory and analgesic pharmaceuticals in sewage and fresh water: treatability by conventional and non-conventional processes, J. Hazard. Mater., 187, 24, 10.1016/j.jhazmat.2011.01.057 Ziylan-Yavas, 2018, Single, simultaneous and sequential applications of ultrasonic frequencies for the elimination of ibuprofen in water, Ultrason. Sonochem., 40, 17, 10.1016/j.ultsonch.2017.01.032