Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases

Cell - Tập 120 - Trang 649-661 - 2005
Hideaki Kamata1,2,3, Shi-ichi Honda3, Shin Maeda1,2, Lufen Chang1,2, Hajime Hirata3, Michael Karin1,2
1Laboratory of Gene Regulation and Signal Transduction, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093
2Department of Pharmacology, School of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093
3Graduate School of Life Science, University of Hyogo, Khoto 3-2-1, Kamigori, Hyogo, 678-1297, Japan

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