Metabolic Engineering of Plants for Alkaloid Production
Tài liệu tham khảo
Belbahri, 2000, Different expression of an S-adenosylmethionine synthetase gene in transgenic tobacco callus modifies alkaloid biosynthesis, Biotechnol. Bioeng., 69, 11, 10.1002/(SICI)1097-0290(20000705)69:1<11::AID-BIT2>3.0.CO;2-J
Bell, 1990, Analysis of a cDNA encoding arginine decarboxylase from oat reveals similarity to the Escherichia coli arginine decarboxylase and evidence of protein processing, Mol. Gen. Genet., 224, 431, 10.1007/BF00262438
Berlin, 1993, Increased production of serotonin by suspension and root cultures of Peganum harmala transformed with a tryptophan decarboxylase cDNA clone from Catharanthus roseus, Transgenic Res., 2, 336, 10.1007/BF01976175
Canel, 1998, Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus, Planta, 205, 414, 10.1007/s004250050338
Chahed, 2000, 1-Deoxy-d-xylulose 5-phosphate synthase from periwinkle: cDNA identification and induced gene expression in terpenoid indole alkaloid-producing cells, Plant Physiol. Biochem., 38, 559, 10.1016/S0981-9428(00)00781-6
Chavadej, 1994, Redirection of tryptophan leads to production of low indole glucosinolate canola, Proc. Natl. Acad. Sci. USA, 91, 2166, 10.1073/pnas.91.6.2166
Contin, 1998, The iridoid glucoside secologanin is derived from the novel triose phosphate/pyruvate pathway in a Catharanthus roseus cell culture, FEBS Lett., 434, 413, 10.1016/S0014-5793(98)01022-9
De Luca, 1987, Subcellular localization of enzymes involved in indole alkaloid biosynthesis in Catharanthus roseus, Plant Physiol., 85, 1099, 10.1104/pp.85.4.1099
De Luca, 1989, Regulation of vindoline biosynthesis in Catharanthus roseus: Molecular cloning of the first and last steps in biosynthesis, 154
De Luca, 1998, Indole alkaloid biosynthesis in Catharanthus roseus: The establishment of a model system, 171
De Luca, 2000, The cell and developmental biology of alkaloid biosynthesis, Trends Plant Sci., 5, 168, 10.1016/S1360-1385(00)01575-2
DeScenzo, 1993, Modulation of cellular polyamines in tobacco by transfer and expression of mouse ornithine decarboxylase cDNA, Plant Mol. Biol., 22, 113, 10.1007/BF00039000
Facchini, 2001, Alkaloid biosynthesis in plants: Biochemistry, cell biology, molecular regulation, and metabolic engineering applications, Annu. Rev. Plant Physiol. Plant Mol. Biol., 52, 29, 10.1146/annurev.arplant.52.1.29
Flores, 1987, Use of plant cells and organ culture in the production of biological chemicals, 66
Geerlings, 1999, Alkaloid production by a Cinchona officinalis “Ledgeriana” hairy root culture containing constitutive expression constructs of tryptophan decarboxylase and strictosidine synthase cDNAs from Catharanthus roseus, Plant Cell Rep., 19, 191, 10.1007/s002990050732
Geerlings, 2000, Molecular cloning and analysis of strictosidine β-d-glucosidase, an enzyme in terpenoid indole alkaloid biosynthesis in Catharanthus roseus, J. Biol. Chem., 275, 3051, 10.1074/jbc.275.5.3051
Goddijn, 1995, Overexpression of a tryptophan decarboxylase cDNA in Catharanthus roseus crown gall calluses results in increased tryptamine levels but not in increased terpenoid indole alkaloid production, Transgenic Res., 4, 315, 10.1007/BF01972528
Hamill, 1990, Over-expressing a yeast ornithine decarboxylase gene in transgenic roots of Nicotiana rustica can lead to enhanced nicotine accumulation, Plant Mol. Biol., 15, 27, 10.1007/BF00017721
Hashimoto, 1993, Production of tropane alkaloids in genetically engineered root cultures, Phytochemistry, 32, 713, 10.1016/S0031-9422(00)95159-8
Hashimoto, 1994, Alkaloid biogenesis: Molecular aspects, Annu. Rev. Plant Physiol. Plant Mol. Biol., 45, 257, 10.1146/annurev.pp.45.060194.001353
Herminghaus, 1996, Improved metabolic action of a bacterial lysine decarboxylase gene in tobacco hairy root cultures by its fusion to a rbcS transit peptide coding sequence, Transgenic Res., 5, 193, 10.1007/BF01969709
Hibi, 1994, Gene expression in tobacco low-nicotine mutants, Plant Cell, 6, 723, 10.1105/tpc.6.5.723
Irmler, 2000, Indole alkaloid biosynthesis in Catharanthus roseus: New enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase, Plant J., 24, 797, 10.1046/j.1365-313x.2000.00922.x
Jouhikainen, 1999, Enhancement of scopolamine production in Hyoscyamus muticus L. hairy root cultures by genetic engineering, Planta, 208, 545, 10.1007/s004250050592
Ketchum, 1999, The kinetics of taxoid accumulation in cell suspension cultures of Taxus following elicitation with methyl jasmonate, Biotechnol. Bioeng., 62, 97, 10.1002/(SICI)1097-0290(19990105)62:1<97::AID-BIT11>3.0.CO;2-C
Kutchan, 1995, Alkaloid biosynthesis—The basis for metabolic engineering of medicinal plants, Plant Cell, 7, 1059, 10.2307/3870057
Kutchan, 1996, Heterologous expression of alkaloid biosynthetic genes—A review, Gene, 179, 73, 10.1016/S0378-1119(96)00426-X
Leech, 1998, Expression of two consecutive genes of a secondary metabolic pathway in transgenic tobacco: Molecular diversity influences levels of expression and product accumulation, Plant Mol. Biol., 38, 765, 10.1023/A:1006000229229
Lichtenthaler, 1999, The 1-deoxy-d-xylulose-5-phosphate pathway of isoprenoid biosynthesis in plants, Annu. Rev. Plant Physiol. Plant Mol. Biol., 50, 47, 10.1146/annurev.arplant.50.1.47
Matsuda, 1991, Molecular cloning of hyoscyamine 6β-hydroxylase, a 2-oxoglutarate-dependent dioxygenase, from cultured roots of Hyoscyamus niger, J. Biol. Chem., 266, 9460, 10.1016/S0021-9258(18)92843-7
McKnight, 1990, Nucleotide sequence of a cDNA encoding the vacuolar protein strictosidine synthase from Catharanthus roseus, Nucleic Acids Res., 18, 4939, 10.1093/nar/18.16.4939
Meijer, 1993, Regulation of enzymes and genes involved in terpenoid indole alkaloid biosynthesis in Catharanthus roseus, J. Plant Res., 3, 145
Meijer, 1993, Isolation and characterization of a cDNA clone from Catharanthus roseus encoding NADPH: Cytochrome P-450 monooxygenases in plants, Plant J., 4, 47, 10.1046/j.1365-313X.1993.04010047.x
Michael, 1996, Molecular cloning and functional identification of a plant ornithine decarboxylase cDNA, Biochem. J., 314, 241, 10.1042/bj3140241
Misra, 1996, Enzymology of indole alkaloid biosynthesis in Catharanthus roseus, Indian J. Biochem. Biophys., 33, 261
Miura, 1988, Formation of vinblastine in multiple shoot culture of Catharanthus roseus, Planta Med., 54, 18, 10.1055/s-2006-962321
Morgan, 1999, Metabolic engineering for the production of plant secondary metabolites, 325
Morgan, 2000, Determination of metabolic rate-limitations by precursor feeding in Catharanthus roseus hairy root cultures, J. Biotechnol., 79, 137, 10.1016/S0168-1656(00)00221-2
Moreno-Valenzuela, 1998, Effect of differentiation on the regulation of indole alkaloid production in Catharanthus roseus hairy roots, Plant Cell Rep., 18, 99, 10.1007/s002990050539
Nakajima, 1993, Two tropinone reductases with different stereospecificities are short-chain dehydrogenases evolved from a common ancestor, Proc. Natl. Acad. Sci. USA, 90, 9591, 10.1073/pnas.90.20.9591
Nakajima, 1999, Two tropinone reductases, that catalyse opposite stereospecific reductions in tropane alkaloid biosynthesis, are localized in plant root with different cell-specific patterns, Plant Cell Physiol., 40, 1099, 10.1093/oxfordjournals.pcp.a029494
O'Keefe, 1997, Stable vindoline production in transformed cell cultures of Catharanthus roseus, J. Nat. Prod., 60, 261, 10.1021/np960703n
Ratcliffe, 2001, Probing plant metabolism with NMR, Annu. Rev. Plant Physiol. Plant Mol. Biol., 52, 499, 10.1146/annurev.arplant.52.1.499
Rhodes, 1989, Regulation of secondary metabolism in transformed root cultures, 58
Roberts, 1999, Biochemistry and physiology of alkaloids and betalains, 17
Robins, 1994, Progress in the genetic engineering of the pyridine and tropane alkaloid biosynthetic pathways of Solanaceous plants, 1
Sato, 2001, Metabolic engineering of plant alkaloid biosynthesis, Proc. Natl. Acad. Sci. USA, 98, 367, 10.1073/pnas.98.1.367
Schroder, 1999, Light-induced cytochrome P450-dependent enzyme in indole alkaloid biosynthesis: Tabersonine 16-hydroxylase, FEBS Lett., 458, 97, 10.1016/S0014-5793(99)01138-2
Shu, 1998, Recent natural products based drug development: A pharmaceutical industry perspective, J. Nat. Prod., 61, 1053, 10.1021/np9800102
St-Pierre, 1998, The terminal O-acetyltransferase involved in vindoline biosynthesis defines a new class of proteins responsible for coenzyme A-dependent acyl transfer, Plant J., 14, 703, 10.1046/j.1365-313x.1998.00174.x
St-Pierre, 1999, Multicellular compartmentation of Catharanthus roseus alkaloid biosynthesis predicts intercellular translocation of a pathway intermediate, Plant Cell, 11, 887, 10.1105/tpc.11.5.887
Suzuki, 1999, Expression of Atropa belladonna putrescine N-methyltransferase gene in root pericycle, Plant Cell Physiol., 40, 189, 10.1093/oxfordjournals.pcp.a029540
van der Fits, 2000, ORCA3, a jasmonate-responsive transcriptional regulator of plant primary and secondary metabolism, Science, 289, 295, 10.1126/science.289.5477.295
Vazquez-Flota, 1997, Molecular cloning and characterization of deacetoxyvindoline 4-hydroxylase, a 2-oxoglutarate dependent dioxygenase involved in the biosynthesis of vindoline in Catharanthus roseus (L.) G. Don, Plant Mol. Biol., 34, 935, 10.1023/A:1005894001516
Veau, 2000, Cloning and expression of cDNAs encoding two enzymes of the MEP pathway in Catharanthus roseus, Biochim. Biophys. Acta, 1517, 159, 10.1016/S0167-4781(00)00240-2
Verpoorte, 2000, Pharmacognosy in the new millenium: Leadfinding and biotechnology, J. Pharm. Pharmacol., 52, 253, 10.1211/0022357001773931
Verpoorte, 1991, Plant biotechnology for the production of alkaloids: Present status and prospects, 1
Verpoorte, 1999, Metabolic engineering of plant secondary metabolite pathways for the production of fine chemicals, Biotech. Lett., 21, 467, 10.1023/A:1005502632053
Verpoorte, 2000, Engineering the plant cell factory for secondary metabolite production, Transgenic Res., 9, 323, 10.1023/A:1008966404981
Walton, 1988, Perturbation of alkaloid production by cadaverine in hairy root cultures of Nicotiana rustica, Plant Sci., 54, 125, 10.1016/0168-9452(88)90090-8
Whitmer, 1998, Influence of precursor availability on alkaloid accumulation by transgenic cell line of Catharanthus roseus, Plant Physiol., 116, 853, 10.1104/pp.116.2.853
Wink, 1999, Plant secondary metabolites: Biochemistry, function, and biotechnology, 1
Yun, 1992, Metabolic engineering of medicinal plants: Transgenic Atropa belladonna with an improved alkaloid composition, Proc. Natl. Acad. Sci. USA, 89, 11799, 10.1073/pnas.89.24.11799
Zenk, 1988, Future trends of exploration for the biotechnological production of isoquinoline alkaloids, 213