Emerging Players in Prostate Cancer–Bone Niche Communication

Trends in Cancer - Tập 7 - Trang 112-121 - 2021
Giulia Furesi1, Martina Rauner1, Lorenz C. Hofbauer1
1Department of Medicine III and Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany

Tài liệu tham khảo

Bray, 2018, Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA Cancer J. Clin., 68, 394, 10.3322/caac.21492 Tay, 2016, Management of prostate cancer in the elderly, Clin. Geriatr. Med., 32, 113, 10.1016/j.cger.2015.08.001 Roudier, 2004, Histological, immunophenotypic and histomorphometric characterization of prostate cancer bone metastases, Cancer Treat. Res., 118, 311, 10.1007/978-1-4419-9129-4_13 Wong, 2019, Prostate cancer and bone metastases: the underlying mechanisms, IJMS, 20, 2587, 10.3390/ijms20102587 Sekita, 2017, Disruption of collagen/apatite alignment impairs bone mechanical function in osteoblastic metastasis induced by prostate cancer, Bone, 97, 83, 10.1016/j.bone.2017.01.004 Guise, 2002, The vicious cycle of bone metastases, J. Musculoskelet. Neuronal Interact., 2, 570 Guise, 2006, Basic mechanisms responsible for osteolytic and osteoblastic bone metastases, Clin. Cancer Res., 12, 6213s, 10.1158/1078-0432.CCR-06-1007 Fizazi, 2003, Prostate cancer cells-osteoblast interaction shifts expression of growth/survival-related genes in prostate cancer and reduces expression of osteoprotegerin in osteoblasts, Clin. Cancer Res., 9, 2587 Ottewell, 2016, The role of osteoblasts in bone metastasis, J. Bone Oncol., 5, 124, 10.1016/j.jbo.2016.03.007 Casimiro, 2016, Molecular mechanisms of bone metastasis: which targets came from the bench to the bedside?, Int. J. Mol. Sci., 17, 1415, 10.3390/ijms17091415 Roodman, 2015, Mechanisms of osteolytic and osteoblastic skeletal lesions, Bonekey Rep., 4, 753 Asadi, 2005, Parathyroid hormone-related protein in prostate cancer, Crit. Rev. Eukaryot. Gene Expr., 15, 15, 10.1615/CritRevEukaryotGeneExpr.v15.i1.20 Liu, 2016, Characteristics and significance of the pre-metastatic niche, Cancer Cell, 30, 668, 10.1016/j.ccell.2016.09.011 Shiao, 2016, Regulation of prostate cancer progression by the tumor microenvironment, Cancer Lett., 380, 340, 10.1016/j.canlet.2015.12.022 Willms, 2018, Extracellular vesicle heterogeneity: subpopulations, isolation techniques, and diverse functions in cancer progression, Front. Immunol., 9, 738, 10.3389/fimmu.2018.00738 Saber, 2020, Exosomes are the driving force in preparing the soil for the metastatic seeds: lessons from the prostate cancer, Cells, 9, 564, 10.3390/cells9030564 Yáñez-Mó, 2015, Biological properties of extracellular vesicles and their physiological functions, J. Extracell Vesicles, 4, 10.3402/jev.v4.27066 Vlaeminck-Guillem, 2018, Extracellular vesicles in prostate cancer carcinogenesis, diagnosis, and management, Front. Oncol., 8, 222, 10.3389/fonc.2018.00222 Huang, 2019, Current progresses of exosomes as cancer diagnostic and prognostic biomarkers, Int. J. Biol. Sci., 15, 1, 10.7150/ijbs.27796 Scimeca, 2018, Prostate osteoblast-like cells: a reliable prognostic marker of bone metastasis in prostate cancer patients, Contrast Media Mol. Imaging, 2018, 10.1155/2018/9840962 Decker, 2017, Biochemical changes in the niche following tumor cell invasion, J. Cell. Biochem., 118, 1956, 10.1002/jcb.25843 Wang, 2014, Prostate cancer cells preferentially home to osteoblast-rich areas in the early stages of bone metastasis: evidence from in vivo models, J. Bone Miner. Res., 29, 2688, 10.1002/jbmr.2300 Costa-Silva, 2015, Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver, Nat. Cell Biol., 17, 816, 10.1038/ncb3169 Peinado, 2017, Pre-metastatic niches: organ-specific homes for metastases, Nat. Rev. Cancer, 17, 302, 10.1038/nrc.2017.6 Psaila, 2009, The metastatic niche: adapting the foreign soil, Nat. Rev. Cancer, 9, 285, 10.1038/nrc2621 Hoshino, 2015, Tumour exosome integrins determine organotropic metastasis, Nature, 527, 329, 10.1038/nature15756 Zaborowski, 2015, Extracellular vesicles: composition, biological relevance, and methods of study, Bioscience, 65, 783, 10.1093/biosci/biv084 Turturici, 2014, Extracellular membrane vesicles as a mechanism of cell-to-cell communication: advantages and disadvantages, Am. J. Phys. Cell Phys., 306, C621, 10.1152/ajpcell.00228.2013 Théry, 2018, Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines, J. Extracell Vesicles, 7, 10.1080/20013078.2018.1535750 Zhang, 2018, Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation, Nat. Cell Biol., 20, 332, 10.1038/s41556-018-0040-4 Lorenc, 2020, Exosomes in prostate cancer diagnosis, prognosis and therapy, Int. J. Mol. Sci., 21, 2118, 10.3390/ijms21062118 Itoh, 2012, Microvesicles released from hormone-refractory prostate cancer cells facilitate mouse pre-osteoblast differentiation, J. Mol. Histol., 43, 509, 10.1007/s10735-012-9415-1 Probert, 2019, Communication of prostate cancer cells with bone cells via extracellular vesicle RNA; a potential mechanism of metastasis, Oncogene, 38, 1751, 10.1038/s41388-018-0540-5 Ye, 2017, Exosomal miR-141-3p regulates osteoblast activity to promote the osteoblastic metastasis of prostate cancer, Oncotarget, 8, 94834, 10.18632/oncotarget.22014 Foj, 2017, Exosomal and non-exosomal urinary miRNAs in prostate cancer detection and prognosis, Prostate, 77, 573, 10.1002/pros.23295 Li, 2019, Exosomes from LNCaP cells promote osteoblast activity through miR-375 transfer, Oncol. Lett., 17, 4463 Hashimoto, 2018, Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A, Proc. Natl. Acad. Sci. U. S. A., 115, 2204, 10.1073/pnas.1717363115 Scavo, 2019, Frizzled-10 extracellular vesicles plasma concentration is associated with tumoral progression in patients with colorectal and gastric cancer, J. Oncol., 2019, 10.1155/2019/2715968 Hu, 2019, Exosomal Wnt-induced dedifferentiation of colorectal cancer cells contributes to chemotherapy resistance, Oncogene, 38, 1951, 10.1038/s41388-018-0557-9 Isola, 2017, Exosomes: the messengers of health and disease, Curr. Neuropharmacol., 15, 157, 10.2174/1570159X14666160825160421 Inder, 2014, Cavin-1/PTRF alters prostate cancer cell-derived extracellular vesicle content and internalization to attenuate extracellular vesicle-mediated osteoclastogenesis and osteoblast proliferation, J. Extracell Vesicles, 3, 10.3402/jev.v3.23784 Moon, 2014, PTRF/cavin-1 neutralizes non-caveolar caveolin-1 microdomains in prostate cancer, Oncogene, 33, 3561, 10.1038/onc.2013.315 Panigrahi, 2018, Hypoxia-induced exosome secretion promotes survival of African-American and Caucasian prostate cancer cells, Sci. Rep., 8, 3853, 10.1038/s41598-018-22068-4 Datta, 2017, Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells, Cancer Lett., 408, 73, 10.1016/j.canlet.2017.08.020 Morhayim, 2015, Proteomic signatures of extracellular vesicles secreted by nonmineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth, FASEB J., 29, 274, 10.1096/fj.14-261404 Bilen, 2017, Proteomics profiling of exosomes from primary mouse osteoblasts under proliferation versus mineralization conditions and characterization of their uptake into prostate cancer cells, J. Proteome Res., 16, 2709, 10.1021/acs.jproteome.6b00981 Knerr, 2004, Bone metastasis: osteoblasts affect growth and adhesion regulons in prostate tumor cells and provoke osteomimicry, Int. J. Cancer, 111, 152, 10.1002/ijc.20223 Hagberg Thulin, 2014, Osteoblasts stimulate the osteogenic and metastatic progression of castration-resistant prostate cancer in a novel model for in vitro and in vivo studies, Clin. Exp. Metastasis, 31, 269, 10.1007/s10585-013-9626-1 Gardner, 2009, Differential expression of osteocalcin during the metastatic progression of prostate cancer, Oncol. Rep., 21, 903 van der Deen, 2010, The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells, J. Cell. Biochem., 109, 828, 10.1002/jcb.22463 Kim, 2020, A CTGF-RUNX2-RANKL axis in breast and prostate cancer cells promotes tumor progression in bone, J. Bone Miner. Res., 35, 155, 10.1002/jbmr.3869 Akech, 2010, Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions, Oncogene, 29, 811, 10.1038/onc.2009.389 Yuen, 2008, TWIST modulates prostate cancer cell-mediated bone cell activity and is upregulated by osteogenic induction, Carcinogenesis, 29, 1509, 10.1093/carcin/bgn105 Regard, 2012, Wnt signaling in bone development and disease: making stronger bone with Wnts, Cold Spring Harb. Perspect. Biol., 4, 10.1101/cshperspect.a007997 Houschyar, 2019, Wnt pathway in bone repair and regeneration – what do we know so far, Front. Cell Dev. Biol., 6, 170, 10.3389/fcell.2018.00170 Steinhart, 2018, Wnt signaling in development and tissue homeostasis, Development, 145, 10.1242/dev.146589 Zhan, 2017, Wnt signaling in cancer, Oncogene, 36, 1461, 10.1038/onc.2016.304 Thiele, 2018, Role of WNT5A receptors FZD5 and RYK in prostate cancer cells, Oncotarget, 9, 27293, 10.18632/oncotarget.25551 Hall, 2006, The role of Wnts in bone metastases, Cancer Metastasis Rev., 25, 551, 10.1007/s10555-006-9022-2 Zheng, 2013, Role of WNT7B-induced noncanonical pathway in advanced prostate cancer, Mol. Cancer Res., 11, 482, 10.1158/1541-7786.MCR-12-0520 Miyamoto, 2015, RNA-seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance, Science, 349, 1351, 10.1126/science.aab0917 Dai, 2008, Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms, Cancer Res., 68, 5785, 10.1158/0008-5472.CAN-07-6541 Darby, 2008, BMP-6 over-expression in prostate cancer is associated with increased Id-1 protein and a more invasive phenotype, J. Pathol., 214, 394, 10.1002/path.2292 Li, 2018, Prognostic value of serum alkaline phosphatase in the survival of prostate cancer: evidence from a meta-analysis, Cancer Manag. Res., 10, 3125, 10.2147/CMAR.S174237 Logothetis, 2005, Osteoblasts in prostate cancer metastasis to bone, Nat. Rev. Cancer, 5, 21, 10.1038/nrc1528 Yu-Lee, 2018, Osteoblast-secreted factors mediate dormancy of metastatic prostate cancer in the bone via activation of the TGFβRIII-p38MAPK-pS249/T252RB pathway, Cancer Res., 78, 2911, 10.1158/0008-5472.CAN-17-1051 Lee, 2018, Dual targeting c-met and VEGFR2 in osteoblasts suppresses growth and osteolysis of prostate cancer bone metastasis, Cancer Lett., 414, 205, 10.1016/j.canlet.2017.11.016 Yan, 2020, Effects of the bone/bone marrow microenvironments on prostate cancer cells and CD59 expression, Biomed. Res. Int., 2020, 10.1155/2020/2753414 Mishra, 2019, Epigenetic changes in fibroblasts drive cancer metabolism and differentiation, Endocr. Relat. Cancer, 26, R673, 10.1530/ERC-19-0347 Comito, 2014, Cancer-associated fibroblasts and M2-polarized macrophages synergize during prostate carcinoma progression, Oncogene, 33, 2423, 10.1038/onc.2013.191 Ortiz-Otero, 2020, Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression, Oncotarget, 11, 1037, 10.18632/oncotarget.27510 Kolb, 2019, Osteoblasts are ‘educated’ by crosstalk with metastatic breast cancer cells in the bone tumor microenvironment, Breast Cancer Res., 21, 31, 10.1186/s13058-019-1117-0 Shiozawa, 2011, Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow, J. Clin. Invest., 121, 1298, 10.1172/JCI43414 Pedersen, 2012, The prostate cancer bone marrow niche: more than just ‘fertile soil’, Asian J. Androl., 14, 423, 10.1038/aja.2011.164 Calvi, 2003, Osteoblastic cells regulate the haematopoietic stem cell niche, Nature, 425, 841, 10.1038/nature02040 Sun, 2007, Expression and activation of αvβ3 integrins by SDF-1/CXC12 increases the aggressiveness of prostate cancer cells, Prostate, 67, 61, 10.1002/pros.20500 Wang, 2007, The pivotal role of CXCL12 (SDF-1)/CXCR4 axis in bone metastasis, Cancer Metastasis Rev., 25, 573, 10.1007/s10555-006-9019-x Sun, 2005, Skeletal localization and neutralization of the SDF-1(CXCL12)/CXCR4 axis blocks prostate cancer metastasis and growth in osseous sites in vivo, J. Bone Miner. Res., 20, 318, 10.1359/JBMR.041109 Kimura, 2017, Alteration of osteoblast arrangement via direct attack by cancer cells: New insights into bone metastasis, Sci. Rep., 7, 10.1038/srep44824 Zhang, 2015, Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration, Oncotarget, 6, 11640, 10.18632/oncotarget.3449 Wu, 2019, Emerging roles of gap junction proteins connexins in cancer metastasis, chemoresistance and clinical application, J. Biomed. Sci., 26, 8, 10.1186/s12929-019-0497-x Wang, 2018, The osteogenic niche is a calcium reservoir of bone micrometastases and confers unexpected therapeutic vulnerability, Cancer Cell, 34, 823, 10.1016/j.ccell.2018.10.002 Waning, 2019, A ‘connexin’ responsible for the fatal attraction of cancer to bone, Cell Metab., 29, 6, 10.1016/j.cmet.2018.12.014 Meng, 2018, Loss of TGF-β signaling in osteoblasts increases basic-FGF and promotes prostate cancer bone metastasis, Cancer Lett., 418, 109, 10.1016/j.canlet.2018.01.018 Yoshimura, 2018, The chemokine MCP-1 (CCL2) in the host interaction with cancer: a foe or ally?, Cell. Mol. Immunol., 15, 335, 10.1038/cmi.2017.135 Verhoef, 2016, MET expression during prostate cancer progression, Oncotarget, 7, 31029, 10.18632/oncotarget.8829 Nordby, 2015, Stromal expression of VEGF-A and VEGFR-2 in prostate tissue is associated with biochemical and clinical recurrence after radical prostatectomy, Prostate, 75, 1682, 10.1002/pros.23048 Bertoldo, 2016 Wu, 2017, MAOA-dependent activation of Shh-IL6-RANKL signaling network promotes prostate cancer metastasis by engaging tumor-stromal cell interactions, Cancer Cell, 31, 368, 10.1016/j.ccell.2017.02.003 Hoey, 2019, Circulating miRNAs as non-invasive biomarkers to predict aggressive prostate cancer after radical prostatectomy, J. Transl. Med., 17, 173, 10.1186/s12967-019-1920-5 Barceló, 2019, Semen miRNAs contained in exosomes as non-invasive biomarkers for prostate cancer diagnosis, Sci. Rep., 9, 10.1038/s41598-019-50172-6