High-yield production of erythritol from raw glycerol in fed-batch cultures of Yarrowia lipolytica

An acetate-negative mutant of Yarrowia lipolytica Wratislavia K1 was selected that, when grown with 300 g raw glycerol l−1 at pH 3, produced 170 g erythritol l−1 after 7 days, corresponding to a 56% yield and a productivity of 1 g l−1 h−1. The Wratislavia K1 strain did not produce citric acid.